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公开(公告)号：US09138380B2
公开(公告)日：2015-09-22
申请号：US13805557
申请日：2011-06-20
申请人： Olof Jansson , Lennart Jonsson , Torbjorn Linden , Jan Sternby , Ragnar Tryggvason , Anders Wieslander
发明人： Olof Jansson , Lennart Jonsson , Torbjorn Linden , Jan Sternby , Ragnar Tryggvason , Anders Wieslander
CPC分类号： A61J1/20 , A61J1/2093 , A61M1/1656 , A61M1/1666 , A61M1/1668 , A61M1/167 , A61M1/287 , B65D31/14 , B65D81/18 , B65D81/20 , B65D81/2007 , B65D81/2023 , B65D81/2046
摘要： A package has a transport/storage state for storing powdery material which is to be mixed with a solvent to form a medical solution. The package includes a compartment which is at least partially defined by two opposing wall portions, and a connector. In the transport/storage state, the compartment contains the powdery material in the form of at least two distinct sets of powdery material of different compositions, where the opposing wall portions are brought into engagement with the powdery material so as to immobilize the sets of powdery material. When used for preparation of the medical solution, a fluid is selectively admitted into the package via the connector so as to expand the compartment and enable mixing of the sets of powdery material with the solvent in the compartment.
摘要翻译： 包装具有用于储存待与溶剂混合以形成医用溶液的粉末状材料的运输/储存状态。 该包装包括至少部分地由两个相对的壁部分限定的隔室和连接器。 在运输/储存状态下，隔室含有至少两组不同组成的粉末状材料形式的粉状材料，其中相对的壁部分与粉末材料接合，从而固定该组粉末状 材料。 当用于制备医用溶液时，通过连接器将流体选择性地进入包装中，以便使隔室膨胀并且使得能够将该组粉末材料与隔室中的溶剂混合。
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公开(公告)号：US20130190681A1
公开(公告)日：2013-07-25
申请号：US13805557
申请日：2011-06-20
申请人： Olof Jansson , Lennart Jonsson , Torbjorn Linden , Jan Sternby , Ragnar Tryggvason , Anders Wieslander
发明人： Olof Jansson , Lennart Jonsson , Torbjorn Linden , Jan Sternby , Ragnar Tryggvason , Anders Wieslander
CPC分类号： A61J1/20 , A61J1/2093 , A61M1/1656 , A61M1/1666 , A61M1/1668 , A61M1/167 , A61M1/287 , B65D31/14 , B65D81/18 , B65D81/20 , B65D81/2007 , B65D81/2023 , B65D81/2046
摘要： A package has a transport/storage state for storing powdery material which is to be mixed with a solvent to form a medical solution. The package includes a compartment which is at least partially defined by two opposing wall portions, and a connector. In the transport/storage state, the compartment contains the powdery material in the form of at least two distinct sets of powdery material of different compositions, where the opposing wall portions are brought into engagement with the powdery material so as to immobilize the sets of powdery material. When used for preparation of the medical solution, a fluid is selectively admitted into the package via the connector so as to expand the compartment and enable mixing of the sets of powdery material with the solvent in the compartment.
摘要翻译： 包装具有用于储存待与溶剂混合以形成医用溶液的粉末状材料的运输/储存状态。 该包装包括至少部分地由两个相对的壁部分限定的隔室和连接器。 在运输/储存状态下，隔室含有至少两组不同组成的粉末状材料形式的粉状材料，其中相对的壁部分与粉末材料接合，从而固定该组粉末状 材料。 当用于制备医用溶液时，通过连接器将流体选择性地进入包装中，以便使隔室膨胀并且使得能够将该组粉末材料与隔室中的溶剂混合。
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公开(公告)号：US09821102B2
公开(公告)日：2017-11-21
申请号：US14128130
申请日：2012-06-11
申请人： Olof Jansson , Torbjorn Linden , Anders Wieslander
发明人： Olof Jansson , Torbjorn Linden , Anders Wieslander
IPC分类号： A61M1/16 , A61K31/7004 , A61K33/06 , A61K33/14 , A61K33/10 , A61K31/19 , A61K31/191 , A61K31/194 , A61K31/198 , A61K31/366 , A61K31/385 , A61J1/05
CPC分类号： A61M1/1654 , A61J1/05 , A61K31/19 , A61K31/191 , A61K31/194 , A61K31/198 , A61K31/366 , A61K31/385 , A61K31/7004 , A61K33/06 , A61K33/10 , A61K33/14 , A61M1/1666 , A61K2300/00
摘要： The present invention concerns a dialysis acid precursor composition for use during preparation of a dialysis acid concentrate solution and for mixing with water, a sodium containing concentrate, and a bicarbonate containing concentrate into a ready-for-use dialysis solution. Said dialysis acid precursor composition consists of powder components comprising glucose, at least one dry acid and at least one calcium salt, and optionally potassium salt, and magnesium salt. According to the invention said glucose and said at least one calcium salt, are present as anhydrous components in said dialysis acid precursor composition.
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公开(公告)号：US20140377376A1
公开(公告)日：2014-12-25
申请号：US14128130
申请日：2012-06-11
申请人： Olof Jansson , Torbjorn Linden , Anders Wieslander
发明人： Olof Jansson , Torbjorn Linden , Anders Wieslander
IPC分类号： A61M1/16 , A61K33/10 , A61K31/7004 , A61K31/194 , A61K31/191 , A61J1/05 , A61K33/06
CPC分类号： A61M1/1654 , A61J1/05 , A61K31/19 , A61K31/191 , A61K31/194 , A61K31/198 , A61K31/366 , A61K31/385 , A61K31/7004 , A61K33/06 , A61K33/10 , A61K33/14 , A61M1/1666 , A61K2300/00
摘要： The present invention concerns a dialysis acid precursor composition for use during preparation of a dialysis acid concentrate solution and for mixing with water, a sodium containing concentrate, and a bicarbonate containing concentrate into a ready-for-use dialysis solution. Said dialysis acid precursor composition consists of powder components comprising glucose, at least one dry acid and at least one calcium salt, and optionally potassium salt, and magnesium salt. According to the invention said glucose and said at least one calcium salt, are present as anhydrous components in said dialysis acid precursor composition.
摘要翻译： 本发明涉及一种透析酸前体组合物，用于制备透析酸浓缩液，并与水，含钠浓缩物和含碳酸氢盐的浓缩液混合成即用型透析溶液。 所述透析酸前体组合物由包含葡萄糖，至少一种干酸和至少一种钙盐，任选的钾盐和镁盐的粉末组分组成。 根据本发明，所述葡萄糖和所述至少一种钙盐以所述透析酸前体组合物中的无水组分存在。
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公开(公告)号：US09616161B2
公开(公告)日：2017-04-11
申请号：US14128375
申请日：2012-06-11
申请人： Olof Jansson , Torbjorn Linden , Anders Wieslander
发明人： Olof Jansson , Torbjorn Linden , Anders Wieslander
IPC分类号： A61K9/14 , A61M1/16 , A61K9/00 , A61K31/185 , A61K31/7004 , A61K33/10 , B65B1/00 , B65B29/06
CPC分类号： A61K33/10 , A61K9/0029 , A61K9/0095 , A61K9/08 , A61K31/185 , A61K31/194 , A61K31/7004 , A61K33/14 , A61M1/1654 , B65B1/00 , B65B29/06 , A61K2300/00
摘要： The present invention concerns a dialysis acid precursor composition for use during preparation of a dialysis acid concentrate solution and for mixing with water and a bicarbonate containing concentrate into a ready-for-use dialysis solution. Said dialysis acid precursor composition consists of powder components comprising sodium chloride, at least one dry acid and at least one calcium salt, and optionally potassium salt, magnesium salt, and glucose. According to the invention said at least one calcium salt and said optional glucose, are present as anhydrous components in said dialysis acid precursor composition.
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公开(公告)号：US20140225033A1
公开(公告)日：2014-08-14
申请号：US14128375
申请日：2012-06-11
申请人： Olof Jansson , Torbjorn Linden , Anders Wieslander
发明人： Olof Jansson , Torbjorn Linden , Anders Wieslander
CPC分类号： A61K33/10 , A61K9/0029 , A61K9/0095 , A61K9/08 , A61K31/185 , A61K31/194 , A61K31/7004 , A61K33/14 , A61M1/1654 , B65B1/00 , B65B29/06 , A61K2300/00
摘要： The present invention concerns a dialysis acid precursor composition for use during preparation of a dialysis acid concentrate solution and for mixing with water and a bicarbonate containing concentrate into a ready-for-use dialysis solution. Said dialysis acid precursor composition consists of powder components comprising sodium chloride, at least one dry acid and at least one calcium salt, and optionally potassium salt, magnesium salt, and glucose. According to the invention said at least one calcium salt and said optional glucose, are present as anhydrous components in said dialysis acid precursor composition.
摘要翻译： 本发明涉及一种透析酸前体组合物，用于制备透析酸浓缩液，并与水和含碳酸氢盐的浓缩液混合成即用型透析溶液。 所述透析酸前体组合物由包含氯化钠，至少一种干酸和至少一种钙盐，以及任选的钾盐，镁盐和葡萄糖的粉末组分组成。 根据本发明，所述至少一种钙盐和任选的葡萄糖以所述透析酸前体组合物中的无水组分存在。
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公开(公告)号：US20130183389A1
公开(公告)日：2013-07-18
申请号：US13805040
申请日：2011-06-20
IPC分类号： A61K33/14
CPC分类号： A61K33/14 , A61K9/0029 , A61K9/0095 , A61K31/19 , A61K31/191 , A61K31/194 , A61K31/198 , A61K31/366 , A61K31/385 , A61K31/7004 , A61K33/00 , A61K33/06 , A61M1/287 , A61K2300/00
摘要： The present invention concerns a dialysis acid precursor composition for use during preparation of a dialysis acid concentrate solution and for mixing with water and a bicarbonate containing concentrate into a ready-for-use dialysis solution. Said dialysis acid precursor composition consist of powder components comprising sodium chloride, at least one dry acid and at least one magnesium salt, and optionally potassium salt, calcium salt, and glucose. According to the invention said at least one magnesium salt and said optional glucose, are present as anhydrous components in said dialysis acid precursor composition.
摘要翻译： 本发明涉及一种透析酸前体组合物，用于制备透析酸浓缩液，并与水和含碳酸氢盐的浓缩液混合成即用型透析溶液。 所述透析酸前体组合物由包含氯化钠，至少一种干酸和至少一种镁盐，以及任选的钾盐，钙盐和葡萄糖的粉末组分组成。 根据本发明，所述至少一种镁盐和所述任选的葡萄糖以所述透析酸前体组合物中的无水组分存在。
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公开(公告)号：US20090139930A1
公开(公告)日：2009-06-04
申请号：US12090230
申请日：2006-09-25
CPC分类号： A61M1/3472 , A61M1/3479 , A61M1/3482 , A61M1/3486 , A61M1/3686 , A61M1/3687 , A61M1/369 , A61M2205/055 , A61M2205/058
摘要： An apparatus (100) for extracorporeal blood cleaning includes a separation unit (110), at least two processing branches (120; 130) and a mixing unit (140). The separation unit (110) receives 5 incoming blood (B A) and divides off a first fraction (fC) from this blood. The first fraction (fC) contains predominantly blood cells. The separation unit (110) also divides off at least one second fraction (fP), which contains predominantly blood plasma. A first processing branch (120) processes the first fraction (fC) according to a first cleaning process, in which cell-bound substances are removed from the blood cells. As a result, a first cleaned fraction (fC c) containing washed blood cells is produced. A second processing branch (130) processes the second fraction (fP) according to a second cleaning process in which toxins bound on proteins within the plasma and/or toxins dissolved in 15 the plasma are removed, and a second cleaned fraction (fP c) is produced. The second cleaning process is different from the first cleaning process. Thereby each process can be tailored for the requirements of the respective fraction (fC, fP). The mixing unit 20 (140) receives the first and second cleaned fractions (fC c, fP c, combines these fractions (fC c, fP c, and outputs cleaned whole blood (BV).
摘要翻译： 用于体外血液清洁的装置（100）包括分离单元（110），至少两个处理分支（120; 130）和混合单元（140）。 分离单元（110）接收5个进入的血液（B A）并从该血液中分离第一分数（fC）。 第一部分（fC）主要含有血细胞。 分离单元（110）还分离出主要含有血浆的至少一个第二级分（fP）。 第一处理分支（120）根据第一清洁处理处理第一馏分（fC），其中细胞结合物质从血细胞中移除。 结果，产生含洗涤血细胞的第一清洗级分（fC c）。 第二处理分支（130）根据第二清洗过程处理第二馏分（fP），其中除去等离子体中溶解的血浆中的蛋白质和/或溶解于血浆中的毒素的毒素和第二清洗部分（fP c） 生产。 第二次清洗过程与第一次清洗过程不同。 因此，可以针对各个部分（fC，fP）的要求来定制每个过程。 混合单元20（140）接收第一和第二清洗级分（fC c，fP c，将这些级分（fC c，fP c）组合并输出清洁的全血（BV）。
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公开(公告)号：US20130189376A1
公开(公告)日：2013-07-25
申请号：US13805474
申请日：2011-06-20
IPC分类号： A61K33/14 , A61K31/19 , A61K31/7004 , A61K31/191 , A61K31/194
CPC分类号： A61K33/14 , A61K9/0029 , A61K9/0095 , A61K31/185 , A61K31/19 , A61K31/191 , A61K31/194 , A61K31/7004 , A61K33/00 , A61K33/06 , A61K33/10 , A61M1/1666 , A61M1/287 , A61K2300/00
摘要： The present invention concerns a dialysis acid precursor composition for use during preparation of a dialysis acid concentrate solution and for mixing with water, a sodium containing concentrate, and a bicarbonate containing concentrate into a ready-for-use dialysis solution. Said dialysis acid precursor composition consists of powder components comprising glucose, at least one dry acid and at least one magnesium salt, and optionally potassium salt, and calcium salt. According to the invention said glucose and said at least one magnesium salt, are present as anhydrous components in said dialysis acid precursor composition.
摘要翻译： 本发明涉及一种透析酸前体组合物，用于制备透析酸浓缩液，并与水，含钠浓缩物和含碳酸氢盐的浓缩液混合成即用型透析溶液。 所述透析酸前体组合物由包含葡萄糖，至少一种干酸和至少一种镁盐，以及任选的钾盐和钙盐的粉末组分组成。 根据本发明，所述葡萄糖和所述至少一种镁盐以所述透析酸前体组合物中的无水组分存在。
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公开(公告)号：US10993961B2
公开(公告)日：2021-05-04
申请号：US13805040
申请日：2011-06-20
IPC分类号： A61K33/14 , A61K33/00 , A61K9/00 , A61K31/7004 , A61K33/06 , A61M1/28 , A61K31/19 , A61K31/191 , A61K31/366 , A61K31/385 , A61K31/194 , A61K31/198
摘要： The present invention concerns a dialysis acid precursor composition for use during preparation of a dialysis acid concentrate solution and for mixing with water and a bicarbonate containing concentrate into a ready-for-use dialysis solution. Said dialysis acid precursor composition consist of powder components comprising sodium chloride, at least one dry acid and at least one magnesium salt, and optionally potassium salt, calcium salt, and glucose. According to the invention said at least one magnesium salt and said optional glucose, are present as anhydrous components in said dialysis acid precursor composition.
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