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1.发明授权公开(公告)号：US08642659B2
公开(公告)日：2014-02-04
申请号：US13001562
申请日：2009-05-28
申请人： Oliver Springer , Peter Muss , Burghard Gruening , Ursula Maczkiewitz , Mike Farwick , Peter Lersch
发明人： Oliver Springer , Peter Muss , Burghard Gruening , Ursula Maczkiewitz , Mike Farwick , Peter Lersch
IPC分类号： A61K31/155 , C07C279/02
CPC分类号： A61Q5/006 , A61K8/43 , A61Q5/02 , A61Q5/12 , C07C279/08
摘要： The invention relates to ether guanidines of the general formulae (I) and/or salts or hydrates thereof, in which R1=—CH2—CH2—CH2—O—R3 where R3 is, independently of the others, hydrocarbon radicals having greater than or equal to 10 carbon atoms, where part of the ether guanidines has radicals R3 which are branched and part of the ether guanidines has radicals R3 which are unbranched, and R2=independently of the others H or an optionally branched, optionally double-bond-containing hydrocarbon radical having 1 to 30 carbon atoms, and use thereof in hair treatment compositions and hair aftertreatment compositions, in particular for preventing damage by chemical treatment compositions and for repairing hair which is already damaged.
摘要翻译： 本发明涉及通式（I）和/或其盐或水合物的醚胍，其中R 1 = -CH 2 -CH 2 -CH 2 -O-R 3，其中R 3独立地为具有大于或者 等于10个碳原子，其中部分醚胍具有支链的基团R3，部分醚胍具有未分支的基团R 3，R 2 =独立地为H或任选支链的任选含双键的 具有1至30个碳原子的烃基，以及其在头发处理组合物和毛发后处理组合物中的用途，特别是用于防止化学处理组合物的损伤和用于修复已经损坏的毛发。
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2.发明申请HAIR TREATMENT PRODUCT AND HAIR AFTER-TREATMENT PRODUCT CONTAINING ETHER GUANIDINES AS ACTIVE SUBSTANCES, FOR PROTECTING FROM DAMAGE CAUSED BY CHEMICAL TREATMENT AND FOR REPAIRING ALREADY DAMAGED HAIR 失效头发处理产品和头发后处理含有作为活性物质的含量的产品，用于保护化学处理造成的损坏和修复已损坏的发胶公开(公告)号：US20110117219A1
公开(公告)日：2011-05-19
申请号：US13001562
申请日：2009-05-28
申请人： Oliver Springer , Peter Muss , Burghard Gruening , Ursula Maczkiewitz , Mike Farwick , Peter Lersch
发明人： Oliver Springer , Peter Muss , Burghard Gruening , Ursula Maczkiewitz , Mike Farwick , Peter Lersch
IPC分类号： A61K36/254 , C07C277/00 , A61K31/155 , A61K36/886 , A61K31/197 , A61K31/40 , A61K31/555 , A61K36/00 , A61K36/752 , A61K36/82 , A61Q5/00
CPC分类号： A61Q5/006 , A61K8/43 , A61Q5/02 , A61Q5/12 , C07C279/08
摘要： The invention relates to ether guanidines of the general formulae (I) and/or salts or hydrates thereof, in which R1=—CH2—CH2—CH2—O—R3 where R3 is, independently of the others, hydrocarbon radicals having greater than or equal to 10 carbon atoms, where part of the ether guanidines has radicals R3 which are branched and part of the ether guanidines has radicals R3 which are unbranched, and R2=independently of the others H or an optionally branched, optionally double-bond-containing hydrocarbon radical having 1 to 30 carbon atoms, and use thereof in hair treatment compositions and hair aftertreatment compositions, in particular for preventing damage by chemical treatment compositions and for repairing hair which is already damaged.
摘要翻译： 本发明涉及通式（I）和/或其盐或水合物的醚胍，其中R 1 = -CH 2 -CH 2 -CH 2 -O-R 3，其中R 3独立地为具有大于或者 等于10个碳原子，其中部分醚胍具有支链的基团R3，部分醚胍具有未分支的基团R 3，R 2 =独立地为H或任选支链的任选含双键的 具有1至30个碳原子的烃基，以及其在头发处理组合物和毛发后处理组合物中的用途，特别是用于防止化学处理组合物的损伤和用于修复已经损坏的毛发。
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公开(公告)号：US20120134948A1
公开(公告)日：2012-05-31
申请号：US13389115
申请日：2010-07-19
申请人： Oliver Springer , Peter Muss , Peter Lersch , Ursula Maczkiewitz , Mike Farwick
发明人： Oliver Springer , Peter Muss , Peter Lersch , Ursula Maczkiewitz , Mike Farwick
IPC分类号： A61K8/43 , A61K31/155 , A61Q15/00 , A01P1/00 , A61P31/00 , A61P31/04 , A01N37/52 , C07C279/08 , A61P17/10
CPC分类号： A61K31/155 , A01N47/44 , A61K8/43 , A61K9/0014 , A61Q15/00 , A61Q17/005 , A01N31/02 , A01N33/12 , A01N43/90 , A01N59/16 , A01N2300/00
摘要： The present invention relates to the use of at least one ether guanidine of the general formula (I) and/or of a salt or hydrate thereof, in which R1═—CH2—CH2—CH2—O—R3, where R3 is a linear or branched hydrocarbon radical having 6 to 22 carbon atoms, and R2═H or an optionally branched hydrocarbon radical which has 1 to 22 C atoms and which optionally comprises double bonds, for reducing the growth of microorganisms, and to cosmetic and pharmaceutical formulations comprising at least one ether guanidine of the general formulae (I).
摘要翻译： 本发明涉及至少一种通式（I）和/或其盐或水合物的醚胍，其中R 1 = -CH 2 -CH 2 -CH 2 -O-R 3，其中R 3是直链的 或具有6至22个碳原子的支链烃基，以及R2 = H或具有1至22个C原子且任选包含双键的任选支化的烃基，用于减少微生物的生长，以及包含在 至少一种通式（I）的醚胍。
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4.发明申请Topical cosmetic formulations for regulating and improving the moisture content of the skin 审中-公开用于调节和改善皮肤含水量的局部化妆品配方公开(公告)号：US20060275238A1
公开(公告)日：2006-12-07
申请号：US11441659
申请日：2006-05-26
申请人： Heike Blasko-Begoihn , Mike Farwick , Peter Lersch , Ursula Maczkiewitz , Maria Mecking , Ralph Scheuermann , Christian Weitemeyer
发明人： Heike Blasko-Begoihn , Mike Farwick , Peter Lersch , Ursula Maczkiewitz , Maria Mecking , Ralph Scheuermann , Christian Weitemeyer
摘要： Cosmetic and/or dermatological formulations for the topical treatment of the skin for regulating and improving the moisture content of the skin, comprising as active ingredient combination a) at least one anionic polyamino acid matrix, b) at least one polysaccharide, and optionally c) one or more osmoprotectants for topical application are provided.
摘要翻译： 用于局部治疗皮肤以调节和改善皮肤水分含量的化妆品和/或皮肤病学制剂，其包含作为活性成分的组合a）至少一种阴离子聚氨基酸基质，b）至少一种多糖，以及任选地c） 提供一种或多种用于局部应用的渗透保护剂。
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5.发明授权公开(公告)号：US09456973B2
公开(公告)日：2016-10-04
申请号：US14453161
申请日：2014-08-06
摘要： The present invention relates to a cosmetic formulation comprising certain methionyl-methionine stereoisomers and to the use of methionyl-methionine for nail and/or hair treatment.
摘要翻译： 本发明涉及包含某些甲硫氨酰 - 甲硫氨酸立体异构体的化妆品制剂以及甲硫氨酰甲硫氨酸用于指甲和/或毛发处理的用途。
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公开(公告)号：US08420137B2
公开(公告)日：2013-04-16
申请号：US13106532
申请日：2011-05-12
IPC分类号： A61K36/906 , A61K36/00
CPC分类号： A61K36/9066 , A61K8/97 , A61K2800/522 , A61Q19/004 , A61Q19/007 , A61Q19/08
摘要： The invention relates to a process for the preparation of a plant extract from Curcuma plants, characterized by the process steps process step A) liquid extraction of Curcuma rhizomes, process step B) optionally, separation of a curcuminoid-containing solid obtained by precipitation from the extraction mixture obtained in process step A), process step C) removal of solvents present from the extraction mixture obtained in process step A) or B) to obtain a concentrate and process step D) distillation of the concentrate at a pressure of less than 1 bar to give the extract as distillate.
摘要翻译： 本发明涉及一种从姜黄植物制备植物提取物的方法，其特征在于步骤A）液体提取姜黄根茎，方法步骤B）任选地，通过沉淀得到的含有姜黄素的固体分离 在方法步骤A）中获得的萃取混合物，方法步骤C）从方法步骤A）或B）中获得的萃取混合物中除去存在的溶剂，以获得浓缩物和方法步骤D）在小于1的压力下蒸馏浓缩物 酒精提取物作为馏出物。
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公开(公告)号：US20100266512A1
公开(公告)日：2010-10-21
申请号：US12809809
申请日：2008-12-10
申请人： Hans Henning Wenk , Mike Farwick , Sandra Nattland , Ursula MacZkiewitz , Birgitte Moelholm Malle
发明人： Hans Henning Wenk , Mike Farwick , Sandra Nattland , Ursula MacZkiewitz , Birgitte Moelholm Malle
IPC分类号： A61K9/12 , A61K8/18 , A61K8/73 , A61Q1/00 , A61Q5/00 , C12P19/04 , C08B37/08 , A61Q17/04 , A61Q15/00 , A61Q19/00 , A61Q3/00 , A61Q11/00 , A61K8/00 , C11D17/00 , A61Q13/00
CPC分类号： C08B37/0072 , A61K8/025 , A61K8/37 , A61K8/375 , A61K8/608 , A61K8/735 , A61K8/894 , A61Q19/08 , C08J3/07 , C08J3/26 , C08J2305/08 , C08L5/08 , Y10T428/2982
摘要： The present invention relates to methods of producing crosslinked hyaluronic acid microbeads, as well as the produced microbeads, said method comprising the steps of: (a) providing an aqueous alkaline solution comprising hyaluronic acid, or a salt thereof; (b) forming microdroplets having a desired size from the mixed solution of step (a) in an organic or oil phase to form a water in organic or water in oil (VWO) emulsion, wherein the amount of oil phase used is of from 20 to less than 50% by weight based on the sum of oil phase and water; (c) adding a solution comprising a crosslinking agent to the emulsion, whereby the reaction of hyaluronic acid with the crosslinking agent takes place to provide crosslinked hyaluronic acid microbeads; and (d) optionally working up the dispersion of crosslinked hyaluronic acid microbeads obtained in step (c).
摘要翻译： 本发明涉及生产交联透明质酸微珠的方法以及生产的微珠，所述方法包括以下步骤：（a）提供包含透明质酸或其盐的碱性水溶液; （b）从有机或油相的步骤（a）的混合溶液中形成具有所需尺寸的微滴，以形成有机油或水包油（VWO）乳液中的水，其中使用的油相量为20 至小于50重量％，基于油相和水的总和; （c）向乳液中加入包含交联剂的溶液，由此发生透明质酸与交联剂的反应以提供交联的透明质酸微珠; 和（d）任选处理步骤（c）中获得的交联透明质酸微珠的分散体。
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公开(公告)号：US09109051B2
公开(公告)日：2015-08-18
申请号：US12809809
申请日：2008-12-10
申请人： Hans Henning Wenk , Mike Farwick , Sandra Nattland , Ursula Maczkiewitz , Birgitte Moelholm Malle
发明人： Hans Henning Wenk , Mike Farwick , Sandra Nattland , Ursula Maczkiewitz , Birgitte Moelholm Malle
IPC分类号： C08B37/08 , A61K8/37 , A61K8/60 , A61K8/73 , A61K8/894 , A61Q19/08 , C08J3/07 , C08J3/26 , C08L5/08 , A61K8/02
CPC分类号： C08B37/0072 , A61K8/025 , A61K8/37 , A61K8/375 , A61K8/608 , A61K8/735 , A61K8/894 , A61Q19/08 , C08J3/07 , C08J3/26 , C08J2305/08 , C08L5/08 , Y10T428/2982
摘要： The present invention relates to methods of producing crosslinked hyaluronic acid microbeads, as well as the produced microbeads, said method comprising the steps of: (a) providing an aqueous alkaline solution comprising hyaluronic acid, or a salt thereof; (b) forming microdroplets having a desired size from the mixed solution of step (a) in an organic or oil phase to form a water in organic or water in oil (VWO) emulsion, wherein the amount of oil phase used is of from 20 to less than 50% by weight based on the sum of oil phase and water; (c) adding a solution comprising a crosslinking agent to the emulsion, whereby the reaction of hyaluronic acid with the crosslinking agent takes place to provide crosslinked hyaluronic acid microbeads; and (d) optionally working up the dispersion of crosslinked hyaluronic acid microbeads obtained in step (c).
摘要翻译： 本发明涉及生产交联透明质酸微珠的方法以及生产的微珠，所述方法包括以下步骤：（a）提供包含透明质酸或其盐的碱性水溶液; （b）从有机或油相的步骤（a）的混合溶液中形成具有所需尺寸的微滴，以形成有机油或水包油（VWO）乳液中的水，其中使用的油相量为20 至小于50重量％，基于油相和水的总和; （c）向乳液中加入包含交联剂的溶液，由此发生透明质酸与交联剂的反应以提供交联的透明质酸微珠; 和（d）任选处理步骤（c）中获得的交联透明质酸微珠的分散体。
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公开(公告)号：US20120258155A1
公开(公告)日：2012-10-11
申请号：US13529425
申请日：2012-06-21
申请人： Hans Henning Wenk , Mike Farwick , Sandra Nattland , Ursula Maczkiewitz , Birgitte Moelholm Malle
发明人： Hans Henning Wenk , Mike Farwick , Sandra Nattland , Ursula Maczkiewitz , Birgitte Moelholm Malle
IPC分类号： A61K8/73 , A61Q17/04 , A61Q15/00 , A61Q19/04 , A61K8/11 , A61Q19/08 , A61Q5/00 , A61Q19/00 , C08B37/08 , A61Q1/02
CPC分类号： C08B37/0072 , A61K8/025 , A61K8/37 , A61K8/375 , A61K8/608 , A61K8/735 , A61K8/894 , A61Q19/08 , C08J3/07 , C08J3/26 , C08J2305/08 , C08L5/08 , Y10T428/2982
摘要： The present invention relates to methods of producing crosslinked hyaluronic acid microbeads, as well as the produced microbeads, said method comprising the steps of: (a) providing an aqueous alkaline solution comprising hyaluronic acid, or a salt thereof; (b) forming microdroplets having a desired size from the mixed solution of step (a) in an organic or oil phase to form a water in organic or water in oil (W/O) emulsion, wherein the amount of oil phase used is of from 20 to less than 50% by weight based on the sum of oil phase and water; (c) adding a solution comprising a crosslinking agent to the emulsion, whereby the reaction of hyaluronic acid with the crosslinking agent takes place to provide crosslinked hyaluronic acid microbeads; and (d) optionally working up the dispersion of crosslinked hyaluronic acid microbeads obtained in step (c).
摘要翻译： 本发明涉及生产交联透明质酸微珠的方法以及生产的微珠，所述方法包括以下步骤：（a）提供包含透明质酸或其盐的碱性水溶液; （b）从有机或油相的步骤（a）的混合溶液中形成具有所需尺寸的微滴以在有机或水包油（W / O）乳液中形成水，其中使用的油相的量为 基于油相和水的总和为20至小于50重量％; （c）向乳液中加入包含交联剂的溶液，由此发生透明质酸与交联剂的反应以提供交联的透明质酸微珠; 和（d）任选处理步骤（c）中获得的交联透明质酸微珠的分散体。
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公开(公告)号：US20120244094A1
公开(公告)日：2012-09-27
申请号：US13502261
申请日：2010-10-18
申请人： Mike Farwick , Ursula Maczkiewitz , Tim Koehler
发明人： Mike Farwick , Ursula Maczkiewitz , Tim Koehler
摘要： The invention relates to the use of the tetrapeptide PKEK for brightening human skin, for bleaching pigmented spots and/or for leveling out irregularities in skin coloration.
摘要翻译： 本发明涉及四肽PKEK用于增亮人皮肤，漂白色素斑点和/或调平皮肤着色不规则的用途。
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