Raman spectral analysis of pathogens
    5.
    发明授权
    Raman spectral analysis of pathogens 有权
    拉曼光谱分析病原体

    公开(公告)号:US07428045B2

    公开(公告)日:2008-09-23

    申请号:US11206007

    申请日:2005-08-17

    IPC分类号: G01J3/44 G01N21/65

    摘要: Raman scattering of radiation applied to a water sample is used to assess occurrence of a pathogen in the sample. The method is useful for detecting pathogens that are difficult to detect using other methods, such as protozoa. Examples of organisms that can be detected in water samples using these methods include protozoa of the genus Cryptosporidium and the genus Giardia. The methods described herein have important applications, such as for detection of Cryptosporidium organisms in municipal water systems.

    摘要翻译: 使用施加到水样品的辐射的拉曼散射来评估样品中病原体的发生。 该方法可用于检测使用其他方法(如原生动物)难以检测的病原体。 使用这些方法可以在水样中检测的生物体的实例包括隐孢子虫属和贾第虫属的原生动物。 本文描述的方法具有重要的应用,例如用于在市政水系统中检测隐孢子虫生物体。

    Raman Chemical Imaging of Threat Agents Using Pulsed Laser Excitation and Time-Gated Detection
    10.
    发明申请
    Raman Chemical Imaging of Threat Agents Using Pulsed Laser Excitation and Time-Gated Detection 审中-公开
    使用脉冲激光激发和时间门控检测的威胁剂的拉曼化学成像

    公开(公告)号:US20100309464A1

    公开(公告)日:2010-12-09

    申请号:US12619336

    申请日:2009-11-16

    IPC分类号: G01J3/44

    摘要: The disclosure provides for a system and method for detecting a threat agent. A sample is illuminated to produce photons Raman scattered and emitted by the sample. The Raman scattered photons are collected using time-gated detection without collecting the emitted photons. A Raman spectroscopic data set is generated from said Raman scattered photons wherein said Raman spectroscopic data comprises at least one of a Raman spectrum and a Raman chemical image. The Raman spectroscopic data is assessed to thereby determine the presence or absence of a threat agent in the sample. The sample may be in a target area. The sample may be illuminated using a pulsed laser or an intensity modulated laser. The illumination source may be synchronized with a gating element that enables time-gated detection.

    摘要翻译: 本公开提供了用于检测威胁代理的系统和方法。 样品被照亮以产生被样品分散和发射的光子拉曼。 使用时间门控检测收集拉曼散射的光子,而不收集发射的光子。 从所述拉曼散射光子产生拉曼光谱数据集,其中所述拉曼光谱数据包括拉曼光谱和拉曼化学图像中的至少一个。 评估拉曼光谱数据,从而确定样品中威胁剂的存在或不存在。 样本可能在目标区域。 可以使用脉冲激光或强度调制激光来照亮样品。 照明源可以与启用时间门控检测的门控元件同步。