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公开(公告)号：US10519568B2
公开(公告)日：2019-12-31
申请号：US14244276
申请日：2014-04-03
Applicant: Patrick T. Mather , Amir Torbati , Ryan Mather
Inventor： Patrick T. Mather , Amir Torbati , Ryan Mather
Abstract: The present invention relates to a method for incorporating dye and/or nanoparticles into polymer films and into electrospun polymeric nanofibers, and, more specifically, to a method for electrospinning a molecularly homogenous solution of dye (and/or nanoparticles) and polymer dissolved in a mutual solvent leading to uniform distribution of dye across the cross-section of each constituent fiber and to resulting nanofibers with the dye/nanoparticles incorporated therein.
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公开(公告)号：US10368993B2
公开(公告)日：2019-08-06
申请号：US15648721
申请日：2017-07-13
Applicant: James Henderson , Patrick T. Mather
Inventor： James Henderson , Patrick T. Mather
Abstract: A three component system for repairing critically sized bone defects having a first shape memory polymer (SMP) component formed as a scaffold that fills the defects, a second SMP component formed as a restricting sleeve that stabilizes and supports osseointegration and osteoconduction, and a third SMP component formed as a two-dimensional cell culture substrate for engineering periosteal grafts.
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公开(公告)号：US09328209B2
公开(公告)日：2016-05-03
申请号：US12842602
申请日：2010-07-23
Applicant: Patrick T. Mather , Luo Xiaofan
Inventor： Patrick T. Mather , Luo Xiaofan
CPC classification number: C08J5/24 , C08G2280/00 , C08J5/046 , C08J2383/04 , D04H1/587 , D04H1/641 , D04H13/00 , Y10T442/2008 , Y10T442/2369
Abstract: A shape memory composite consisting of an electrospun non-woven fiber mat and an elastomeric resin matrix. The fiber mat is made from a semi-crystalline polymer, poly(ε-caprolactone) (PCL) and serves as the “switching phase” for shape fixing and recovery. The resin matrix, a crosslinked PDMS elastomer, imparts softness as well as entropic elasticity to the material. PCL is first electrospun from a chloroform/DMF solution. The resulting microfiber mat was then immersed in a two-part (base resin and crosslinking agent) mixture of Sylgard 184 with a vacuum applied to infiltrate the fiber mat with the mixture. The infiltrated fiber mat is then removed from the mixture and cured at room temperature for two days.
Abstract translation: 由电纺无纺纤维毡和弹性树脂基体组成的形状记忆复合材料。 纤维毡由半结晶聚合物，聚（ε-己内酯）（PCL）制成，用作形状固定和回收的“切换阶段”。 树脂基质，交联的PDMS弹性体，赋予材料柔软度以及熵弹性。 PCL首先从氯仿/ DMF溶液中电纺丝。 然后将所得的超细纤维垫浸入Sylgard 184的两部分（基础树脂和交联剂）混合物中，并施加真空以用该混合物渗透纤维垫。 然后将渗透的纤维垫从混合物中取出并在室温下固化两天。
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公开(公告)号：US20140303490A1
公开(公告)日：2014-10-09
申请号：US14244276
申请日：2014-04-03
Applicant: Patrick T. Mather , Amir Torbati , Ryan Mather
Inventor： Patrick T. Mather , Amir Torbati , Ryan Mather
CPC classification number: D01D5/0038 , A61B5/064 , A61B2090/3941 , A61B2090/3979 , B82Y30/00 , D01D5/0076 , D01F1/06 , D01F1/10
Abstract: The present invention relates to a method for incorporating dye and/or nanoparticles into polymer films and into electrospun polymeric nanofibers, and, more specifically, to a method for electrospinning a molecularly homogenous solution of dye (and/or nanoparticles) and polymer dissolved in a mutual solvent leading to uniform distribution of dye across the cross-section of each constituent fiber and to resulting nanofibers with the dye/nanoparticles incorporated therein.
Abstract translation: 本发明涉及一种将染料和/或纳米颗粒掺入聚合物膜和电纺聚合物纳米纤维中的方法，更具体地说，涉及一种将分子均匀的染料（和/或纳米颗粒）溶液和溶于 相互溶剂导致染料在每个构成纤维的横截面上均匀分布，并且所得的纳米纤维与其中掺入的染料/纳米颗粒结合。
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公开(公告)号：US20140135889A9
公开(公告)日：2014-05-15
申请号：US12880483
申请日：2010-09-13
Applicant: Ronald A Sahatjian , Francisca Tan , Patrick T. Mather , Changdeng Liu , Cheryl J. Campo
Inventor： Ronald A Sahatjian , Francisca Tan , Patrick T. Mather , Changdeng Liu , Cheryl J. Campo
IPC: A61F2/84
CPC classification number: C08G61/08 , A61F2/88 , A61F2/91 , A61F2/915 , A61F2002/8483 , A61F2002/91541 , A61F2002/9528 , A61F2220/0016 , A61F2250/0039 , A61F2250/0068 , A61L29/14 , A61L31/14 , A61M25/1027 , C08G18/3893 , C08G18/4277 , C08G18/4833 , C08G2230/00 , C08L65/00
Abstract: A medical device includes a balloon catheter having an expandable member, e.g., an inflatable balloon, at its distal end and a stent or other endoprosthesis. The stent is, for example, an apertured tubular member formed of a polymer and is assembled about the balloon. The stent has an initial diameter for delivery into the body and can be expanded to a larger diameter by inflating the balloon.
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Patent Agency Ranking
公开(公告)号：US20140135454A1
公开(公告)日：2014-05-15
申请号：US14079171
申请日：2013-11-13
Applicant: Patrick T. Mather , Gu Xinzhu
Inventor： Patrick T. Mather , Gu Xinzhu
IPC: C08G71/04
CPC classification number: C08G18/4833 , C08G18/4018 , C08G18/4277 , C08G18/771 , C08G2280/00
Abstract: Water-triggered shape memory polymers based on poly(ε-caprolactone) (PCL) and poly(ethylene glycol) (PEG) multiblock hybrid thermoplastic polyurethanes. Urethane linkages were formed through the addition reaction between isocyanate groups of the lysine methyl-ester diisocyanate (LDI) and the hydroxyl groups of either (PEG) or PCL diol.
Abstract translation: 基于聚（ε-己内酯）（PCL）和聚（乙二醇）（PEG）多嵌段杂化热塑性聚氨酯的水触发形状记忆聚合物。 通过赖氨酸甲酯二异氰酸酯（LDI）的异氰酸酯基与（PEG）或PCL二醇的羟基之间的加成反应形成氨基甲酸酯键。
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公开(公告)号：US20140067039A9
公开(公告)日：2014-03-06
申请号：US13493532
申请日：2012-06-11
Applicant: Ronald A. Sahatjian , Francisca Tan , Patrick T. Mather , ChangDeng Liu , Cheryl J. Campo
Inventor： Ronald A. Sahatjian , Francisca Tan , Patrick T. Mather , ChangDeng Liu , Cheryl J. Campo
IPC: A61F2/82
CPC classification number: C08G61/08 , A61F2/88 , A61F2/91 , A61F2/915 , A61F2002/8483 , A61F2002/91541 , A61F2002/9528 , A61F2220/0016 , A61F2250/0039 , A61F2250/0068 , A61L29/14 , A61L31/14 , A61M25/1027 , C08G18/3893 , C08G18/4277 , C08G18/4833 , C08G2230/00 , C08L65/00
Abstract: A medical device includes a balloon catheter having an expandable member, e.g., an inflatable balloon, at its distal end and a stent or other endoprosthesis. The stent is, for example, an apertured tubular member formed of a polymer and is assembled about the balloon. The stent has an initial diameter for delivery into the body and can be expanded to a larger diameter by inflating the balloon.
Abstract translation: 医疗装置包括球囊导管，其具有在其远端处具有可膨胀构件，例如可膨胀气囊，以及支架或其他内置假体。 支架是例如由聚合物形成的多孔管状构件，并围绕气囊组装。 支架具有用于输送到身体中的初始直径，并且可以通过使气囊膨胀而扩展到更大的直径。
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8.发明授权Nonionic telechelic polymers incorporating polyhedral oligosilsesquioxane (POSS) and uses thereof 失效加入多面体低聚倍半硅氧烷（POSS）的非离子遥爪聚合物及其用途公开(公告)号：US07067606B2
公开(公告)日：2006-06-27
申请号：US10620644
申请日：2003-07-16
Applicant: Patrick T. Mather , Byoung-Suhk Kim , Qing Ge , Changdeng Liu
Inventor： Patrick T. Mather , Byoung-Suhk Kim , Qing Ge , Changdeng Liu
IPC: C08G77/04
CPC classification number: C08G18/3893 , C08G18/4833 , C08G18/718 , C08G65/336 , C08L71/02 , C08L2205/05 , C08L83/00
Abstract: Amphiphilic telechelics incorporating polyhedraloligosilsesquioxane (POSS) synthesized by direct urethane linkage between the diol end groups of polyethylene glycol (PEG) homopolymers and the monoisocyanate group of POSS macromers. The hydrophobicity of the amphiphilic telechelics can be varied by using PEG homopolymers of increasing MW, providing for control over molecular architecture by hydrophilic/hydrophobic balance. Methods for synthesizing the amphiphilic telechelics and their use as surfactants, thickening agents, additives to plastic such as PMMA′(Plexiglass), epoxyadhesives for improving their properties are also disclosed.
Abstract translation: 通过在聚乙二醇（PEG）均聚物的二醇端基与POSS大单体的单异氰酸酯基团之间通过直接氨基甲酸酯键合成的多面体聚二甲基倍半硅氧烷（POSS）的两亲电视电影。 通过使用增加MW的PEG均聚物可以改变两亲性电视电泳的疏水性，通过亲水/疏水平衡提供对分子结构的控制。 还公开了合成两亲电视电影的方法及其作为表面活性剂，增稠剂，塑料添加剂如PMMA（有机玻璃）的用途，用于改善其性能的环氧树脂粘合剂。
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公开(公告)号：US20190301064A1
公开(公告)日：2019-10-03
申请号：US16367473
申请日：2019-03-28
Applicant: James Henderson , Patrick T. Mather , Shelby Buffington
Inventor： James Henderson , Patrick T. Mather , Shelby Buffington
IPC: D04H1/4358 , D04H1/728 , D04H1/435 , D04H1/4382 , C12N5/00
Abstract: An enzyme responsive shape memory polymer formed from a glassy, cross-linked shape memory polymer that incorporates ester bonds that are responsive to the present of an enzyme. PCL-based polyurethanes (featuring simple alternation of PCL diol and lysine-based diisocyanate) are degradable by Amano lipase PS. A non-degradable thermoplastic elastomer may be dual electrospun with a polycaprolactone based TPU with the fixing phase compressed so that the composite is ready for enzymatically triggered contraction. Alternatively, the elastomer may be a PCL copolymer-based polyurethane amorphous elastomer that is both degradable and elastomeric and put into compression so that upon enzymatic degradation of the elastomeric phase the scaffold expands.
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公开(公告)号：US10125233B2
公开(公告)日：2018-11-13
申请号：US15503065
申请日：2015-08-11
Applicant: Patrick T. Mather
Inventor： Patrick T. Mather
Abstract: A triple shape memory polymeric foam that is open cell in nature and features a two phase, crosslinked SMP with a glass transition temperature of one phase at a temperature lower than a melting transition of the second phase. The resulting soft material features high fidelity, repeatable triple shape behavior, and is useful for complex deployment using a combination of foam compression and bending.
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