-
1.发明申请NANOPARTICLE AND POLYMER FORMULATIONS FOR THYROID HORMONE ANALOGS, ANTAGONISTS, AND FORMULATIONS AND USES THEREOF 有权用于甲状腺激素类似物的纳米颗粒和聚合物配方，其拮抗剂及其制剂及其用途公开(公告)号：US20110052715A1
公开(公告)日：2011-03-03
申请号：US12816287
申请日：2010-06-15
CPC分类号： A61K9/5031 , A61K31/192 , A61K41/0038 , A61K45/06 , A61K47/58 , A61K47/593 , A61K47/60 , A61K47/61 , A61K47/64 , A61K47/643 , A61K47/645 , A61K47/6455 , A61K47/6937 , B82Y5/00 , Y10T428/2982
摘要： Disclosed are methods of treating subjects having conditions related to angiogenesis including administering an effective amount of a polymeric nanoparticle form of thyroid hormone agonist, partial agonist or an antagonist thereof, to promote or inhibit angiogenesis in the subject. Nanoparticle forms of thyroid hormone or thyroid hormone analogs as well as uses thereof are also disclosed.
摘要翻译： 公开了治疗具有与血管发生相关的病症的受试者的方法，包括施用有效量的甲状腺激素激动剂，部分激动剂或其拮抗剂的聚合物纳米颗粒形式，以促进或抑制受试者的血管发生。 还公开了甲状腺激素或甲状腺激素类似物的纳米颗粒形式及其用途。
-
2.发明授权Nanoparticle and polymer formulations for thyroid hormone analogs, antagonists, and formulations and uses thereof 有权用于甲状腺激素类似物，拮抗剂及其制剂和用途的纳米颗粒和聚合物制剂公开(公告)号：US09220788B2
公开(公告)日：2015-12-29
申请号：US12816287
申请日：2010-06-15
CPC分类号： A61K9/5031 , A61K31/192 , A61K41/0038 , A61K45/06 , A61K47/58 , A61K47/593 , A61K47/60 , A61K47/61 , A61K47/64 , A61K47/643 , A61K47/645 , A61K47/6455 , A61K47/6937 , B82Y5/00 , Y10T428/2982
摘要： Disclosed are methods of treating subjects having conditions related to angiogenesis including administering an effective amount of a polymeric nanoparticle form of thyroid hormone agonist, partial agonist or an antagonist thereof, to promote or inhibit angiogenesis in the subject. Nanoparticle forms of thyroid hormone or thyroid hormone analogs as well as uses thereof are also disclosed.
摘要翻译： 公开了治疗具有与血管发生相关的病症的受试者的方法，包括施用有效量的甲状腺激素激动剂，部分激动剂或其拮抗剂的聚合物纳米颗粒形式，以促进或抑制受试者的血管发生。 还公开了甲状腺激素或甲状腺激素类似物的纳米颗粒形式及其用途。
-
公开(公告)号：US08071134B2
公开(公告)日：2011-12-06
申请号：US11663047
申请日：2005-09-15
申请人： Shaker A. Mousa , Faith B. Davis , Paul J. Davis
发明人： Shaker A. Mousa , Faith B. Davis , Paul J. Davis
CPC分类号： A61K31/192 , A61K31/195 , A61K31/4365 , A61K31/60 , A61K31/7076 , A61K31/727 , A61K38/1825 , A61K38/1866 , A61K47/58 , A61K47/593 , A61K47/60 , A61K47/61 , A61K47/64 , A61K49/0008 , A61K49/085 , A61K49/10 , A61K49/12 , A61K51/0402 , A61K51/0497 , A61K51/065 , A61L27/34 , A61L27/54 , A61L29/085 , A61L29/16 , A61L31/10 , A61L31/16 , A61L2300/43 , A61L2300/606 , A61K2300/00
摘要： Disclosed are methods of treating subjects having conditions related to angiogenesis including administering an effective amount of a polymeric form of thyroid hormone, or an antagonist thereof, to promote or inhibit angiogenesis in the subject. Compositions of the polymeric forms of thyroid hormone, or thyroid hormone analogs, are also disclosed.
摘要翻译： 公开了治疗具有与血管发生相关的病症的受试者的方法，包括施用有效量的甲状腺激素或其拮抗剂的聚合形式，以促进或抑制受试者的血管生成。 还公开了甲状腺激素或甲状腺激素类似物的聚合形式的组合物。
-
公开(公告)号：US20140072646A1
公开(公告)日：2014-03-13
申请号：US13975725
申请日：2013-08-26
申请人： Shaker A. Mousa , Faith B. Davis , Paul J. Davis
发明人： Shaker A. Mousa , Faith B. Davis , Paul J. Davis
IPC分类号： A61K31/198 , A61K45/06 , A61K9/14 , A61K38/18
CPC分类号： A61K31/198 , A61K9/00 , A61K9/146 , A61K31/192 , A61K31/195 , A61K38/1825 , A61K45/06 , A61K47/58 , A61K47/60 , A61K47/61 , A61K2300/00
摘要： Disclosed are methods of treating subjects having conditions related to angiogenesis including administering an effective amount of a polymeric form of thyroid hormone, or an antagonist thereof, to promote or inhibit angiogenesis in the subject. Compositions of the polymeric forms of thyroid hormone, or thyroid hormone analogs, are also disclosed.
-
公开(公告)号：US20140072635A1
公开(公告)日：2014-03-13
申请号：US14078713
申请日：2013-11-13
申请人： Shaker A. Mousa , Faith B. Davis , Paul J. Davis
发明人： Shaker A. Mousa , Faith B. Davis , Paul J. Davis
IPC分类号： A61K31/192 , A61K45/06 , A61K31/7068 , A61K31/225 , A61K31/337
CPC分类号： A61K31/192 , A61K31/225 , A61K31/337 , A61K31/704 , A61K31/7068 , A61K45/06 , A61K2300/00
摘要： Disclosed are methods of treating subjects having conditions related to angiogenesis including administering an effective amount of a polymeric form of thyroid hormone, or an antagonist thereof, to promote or inhibit angiogenesis in the subject. Compositions of the polymeric forms of thyroid hormone, or thyroid hormone analogs, are also disclosed.
摘要翻译： 公开了治疗具有与血管发生相关的病症的受试者的方法，包括施用有效量的甲状腺激素或其拮抗剂的聚合形式，以促进或抑制受试者的血管生成。 还公开了甲状腺激素或甲状腺激素类似物的聚合形式的组合物。
-
公开(公告)号：US20100112079A1
公开(公告)日：2010-05-06
申请号：US12626068
申请日：2009-11-25
申请人： Shaker A. Mousa , Faith B. Davis , Paul J. Davis
发明人： Shaker A. Mousa , Faith B. Davis , Paul J. Davis
IPC分类号： A61K9/14 , A61K31/195 , A61K38/02 , A61K31/7076 , A61K31/727 , A61K38/14 , A61K31/60 , A61K31/4365 , A61K31/19 , A61P9/00
CPC分类号： A61K31/198 , A61K9/00 , A61K9/146 , A61K31/192 , A61K31/195 , A61K38/1825 , A61K45/06 , A61K47/58 , A61K47/60 , A61K47/61 , A61K2300/00
摘要： Disclosed are methods of treating subjects having conditions related to angiogenesis including administering an effective amount of a polymeric form of thyroid hormone, or an antagonist thereof, to promote or inhibit angiogenesis in the subject. Compositions of the polymeric forms of thyroid hormone, or thyroid hormone analogs, are also disclosed.
摘要翻译： 公开了治疗具有与血管发生相关的病症的受试者的方法，包括施用有效量的甲状腺激素或其拮抗剂的聚合形式，以促进或抑制受试者的血管生成。 还公开了甲状腺激素或甲状腺激素类似物的聚合形式的组合物。
-
公开(公告)号：US09198887B2
公开(公告)日：2015-12-01
申请号：US14078713
申请日：2013-11-13
申请人： Shaker A. Mousa , Faith B. Davis , Paul J. Davis
发明人： Shaker A. Mousa , Faith B. Davis , Paul J. Davis
IPC分类号： A61K31/192 , A61K45/06 , A61K31/7068 , A61K31/225 , A61K31/337 , A61K31/704
CPC分类号： A61K31/192 , A61K31/225 , A61K31/337 , A61K31/704 , A61K31/7068 , A61K45/06 , A61K2300/00
摘要： Disclosed are methods of treating subjects having conditions related to angiogenesis including administering an effective amount of a polymeric form of thyroid hormone, or an antagonist thereof, to promote or inhibit angiogenesis in the subject. Compositions of the polymeric forms of thyroid hormone, or thyroid hormone analogs, are also disclosed.
摘要翻译： 公开了治疗具有与血管发生相关的病症的受试者的方法，包括施用有效量的甲状腺激素或其拮抗剂的聚合形式，以促进或抑制受试者的血管生成。 还公开了甲状腺激素或甲状腺激素类似物的聚合形式的组合物。
-
8.发明授权Nanoparticle and polymer formulations for thyroid hormone analogs, antagonists, and formulations thereof 有权用于甲状腺激素类似物，拮抗剂及其制剂的纳米颗粒和聚合物制剂公开(公告)号：US08668926B1
公开(公告)日：2014-03-11
申请号：US11786723
申请日：2007-04-11
申请人： Shaker A. Mousa , Faith B. Davis , Paul J. Davis
发明人： Shaker A. Mousa , Faith B. Davis , Paul J. Davis
IPC分类号： A61K9/127
CPC分类号： A61K31/198 , A61K9/0048 , A61K9/5153 , A61K31/192 , A61K31/195 , A61K31/4365 , A61K31/60 , A61K31/65 , A61K31/7076 , A61K31/727 , A61K39/44 , A61K47/58 , A61K47/593 , A61K47/60 , A61K47/61 , A61K47/64 , A61K47/68 , A61K47/6801 , A61K47/6811 , A61K47/6937 , A61K47/6939 , A61K49/0008 , A61K49/085 , A61K49/10 , A61K49/12 , A61K51/0402 , A61K51/0497 , A61K51/065 , C07K16/2848 , C07K2317/76 , Y10T428/2982
摘要： Disclosed are methods of treating subjects having conditions related to angiogenesis including administering an effective amount of a polymeric Nanoparticle form of thyroid hormone agonist, partial agonist or an antagonist thereof, to promote or inhibit angiogenesis in the subject. Compositions of the polymeric forms of thyroid hormone, or thyroid hormone analogs, are also disclosed.
摘要翻译： 公开了治疗具有与血管发生相关的病症的受试者的方法，包括施用有效量的聚合物纳米颗粒形式的甲状腺激素激动剂，其部分激动剂或其拮抗剂，以促进或抑制受试者的血管生成。 还公开了甲状腺激素或甲状腺激素类似物的聚合形式的组合物。
-
公开(公告)号：US09980933B2
公开(公告)日：2018-05-29
申请号：US13975725
申请日：2013-08-26
申请人： Shaker A. Mousa , Faith B. Davis , Paul J. Davis
发明人： Shaker A. Mousa , Faith B. Davis , Paul J. Davis
IPC分类号： A61K47/48 , A61K31/198 , A61K31/192 , A61K31/195 , A61K45/06 , A61K38/18 , A61K9/14 , A61K47/60 , A61K47/58 , A61K47/61 , A61K9/00
CPC分类号： A61K31/198 , A61K9/00 , A61K9/146 , A61K31/192 , A61K31/195 , A61K38/1825 , A61K45/06 , A61K47/58 , A61K47/60 , A61K47/61 , A61K2300/00
摘要： Disclosed are methods of treating subjects having conditions related to angiogenesis including administering an effective amount of a polymeric form of thyroid hormone, or an antagonist thereof, to promote or inhibit angiogenesis in the subject. Compositions of the polymeric forms of thyroid hormone, or thyroid hormone analogs, are also disclosed.
-
公开(公告)号：US09180107B2
公开(公告)日：2015-11-10
申请号：US12751375
申请日：2010-03-31
申请人： Hung-Yun Lin , Faith B. Davis , Paul J. Davis , Shaker A. Mousa
发明人： Hung-Yun Lin , Faith B. Davis , Paul J. Davis , Shaker A. Mousa
IPC分类号： A01N59/22 , A61K9/14 , A61K9/16 , A61K9/50 , A61K39/00 , A61K39/395 , C07K16/00 , C12P21/08 , A61K31/192 , A61K45/06 , A61K47/48
CPC分类号： A61K31/192 , A61K39/3955 , A61K45/06 , A61K47/6921 , A61K47/6935 , A61K47/6937 , A61K2300/00
摘要： Provided herein are compositions and methods for treating cancer by increasing the inhibitory effect of cetuximab on HIF1α expression by administering cetuximab in combination with anti-angiogenic thyroid hormone analogs such as tetrac or triac.
摘要翻译： 本文提供了通过施用西妥昔单抗联合抗血管生成甲状腺激素类似物如四或三联报来增加西妥昔单抗对HIF1α表达的抑制作用来治疗癌症的组合物和方法。
-
-
-
-
-
-
-
-
-
搜索结果
17 条记录 (耗时 0.046 秒)
