Pyrrolobenzodiazepine derivatives, compositions comprising the same and methods related thereto
    1.
    发明授权
    Pyrrolobenzodiazepine derivatives, compositions comprising the same and methods related thereto 失效
    吡咯并苯并二氮杂衍生物,包含其的组合物及其相关方法

    公开(公告)号:US07511032B2

    公开(公告)日:2009-03-31

    申请号:US10576689

    申请日:2004-10-22

    CPC分类号: C07D487/04

    摘要: Disclosed are compounds of Formula (I) wherein X, Y, Ri-R7, T1, T2, Z, and p are as described herein; a pharmaceutical composition comprising a compound of Formula (I) and a carrier; a method of inhibiting growth of a cell, which method comprises administering in an amount effective to inhibit growth a compound of Formula (I); a method of treating cancer in a mammal, which method comprises administering in an amount effective to treat cancer a compound of Formula (I); a method of treating a viral, parasitic, or bacterial infection of a cell, which method comprises administering in an amount effective to treat a viral, parasitic, or bacterial infection a compound of Formula (I); and a method of preparing a compound of Formula (I) as described herein.

    摘要翻译: 公开了式(I)的化合物,其中X,Y,R 1 -R 7,T 1,T 2,Z和p如本文所述; 包含式(I)化合物和载体的药物组合物; 抑制细胞生长的方法,该方法包括以有效抑制生长的量施用式(I)化合物; 一种治疗哺乳动物癌症的方法,该方法包括以有效治疗癌症的量施用式(I)化合物; 治疗细胞的病毒,寄生或细菌感染的方法,所述方法包括以有效治疗病毒,寄生或细菌感染的量施用式(I)化合物; 和制备本文所述的式(I)化合物的方法。

    Pyrrolobenzodiazepine derivatives, compositions comprising the same and methods related thereto
    2.
    发明授权
    Pyrrolobenzodiazepine derivatives, compositions comprising the same and methods related thereto 有权
    吡咯并苯并二氮杂衍生物,包含其的组合物及其相关方法

    公开(公告)号:US07834005B2

    公开(公告)日:2010-11-16

    申请号:US12370856

    申请日:2009-02-13

    CPC分类号: C07D487/04

    摘要: Disclosed are compounds of Formula I wherein X, Y, R1-R7, T1, T2, Z, and p are as described herein; a pharmaceutical composition comprising a compound of Formula I and a carrier; a method of inhibiting growth of a cell, which method comprises administering in an amount effective to inhibit growth a compound of Formula I; a method of treating cancer in a mammal, which method comprises administering in an amount effective to treat cancer a compound of Formula I; a method of treating a viral, parasitic, or bacterial infection of a cell, which method comprises administering in an amount effective to treat a viral, parasitic, or bacterial infection a compound of Formula I; and a method of preparing a compound of Formula I as described herein.

    摘要翻译: 公开了式I的化合物,其中X,Y,R 1 -R 7,T 1,T 2,Z和p如本文所述; 包含式I化合物和载体的药物组合物; 一种抑制细胞生长的方法,该方法包括以有效抑制生长式I化合物的量给药; 一种治疗哺乳动物癌症的方法,该方法包括以有效治疗癌症的剂量施用式I化合物; 治疗细胞的病毒,寄生或细菌感染的方法,该方法包括以有效治疗式I化合物的病毒,寄生或细菌感染的量施用; 以及制备如本文所述的式I化合物的方法。

    PYRROLOBENZODIAZEPINE DERIVATIVES, COMPOSITIONS COMPRISING THE SAME AND METHODS RELATED THERETO
    3.
    发明申请
    PYRROLOBENZODIAZEPINE DERIVATIVES, COMPOSITIONS COMPRISING THE SAME AND METHODS RELATED THERETO 有权
    吡咯烷酮衍生物,包含该衍生物的组合物及其相关方法

    公开(公告)号:US20090149449A1

    公开(公告)日:2009-06-11

    申请号:US12370856

    申请日:2009-02-13

    CPC分类号: C07D487/04

    摘要: Disclosed are compounds of Formula I wherein X, Y, R1-R7, T1, T2, Z, and p are as described herein; a pharmaceutical composition comprising a compound of Formula I and a carrier; a method of inhibiting growth of a cell, which method comprises administering in an amount effective to inhibit growth a compound of Formula I; a method of treating cancer in a mammal, which method comprises administering in an amount effective to treat cancer a compound of Formula I; a method of treating a viral, parasitic, or bacterial infection of a cell, which method comprises administering in an amount effective to treat a viral, parasitic, or bacterial infection a compound of Formula I; and a method of preparing a compound of Formula I as described herein.

    摘要翻译: 公开了式I的化合物,其中X,Y,R 1 -R 7,T 1,T 2,Z和p如本文所述; 包含式I化合物和载体的药物组合物; 一种抑制细胞生长的方法,该方法包括以有效抑制生长式I化合物的量给药; 一种治疗哺乳动物癌症的方法,该方法包括以有效治疗癌症的剂量施用式I化合物; 治疗细胞的病毒,寄生或细菌感染的方法,该方法包括以有效治疗式I化合物的病毒,寄生或细菌感染的量施用; 以及制备如本文所述的式I化合物的方法。

    Baking treatment of lithographic printing plate
    4.
    发明授权
    Baking treatment of lithographic printing plate 失效
    平面印刷板的烘烤处理

    公开(公告)号:US5168813A

    公开(公告)日:1992-12-08

    申请号:US689875

    申请日:1991-05-22

    IPC分类号: G03F7/40

    CPC分类号: G03F7/40

    摘要: A method of processing a lithographic printing plate which comprises the steps of exposing, developing and baking the plate, in which a pre-baking liquid is applied to the plate prior to the baking step, and which is not tacky, has a long storage life, and does not require rinsing with water after baking. The pre-baking liquid includes one or more of a sulphosuccinamate or sulphosuccinate and a type and present in an amount sufficient to form a non-water soluble baked coating on the developed plate which acts as an effective barrier to contaminating material tending to come into contact with the developed areas of the plate during the baking step, and which has no adverse reaction with the image and non-image areas and allows the plate to be baked, and thereby to improve the durability of the processed plate for use on a press. The baked coating is removed subsequently by an alkaline solution.

    摘要翻译: PCT No.PCT / GB89 / 01167 Sec。 371日期1991年5月22日 102(e)日期1991年5月22日PCT提交1989年10月2日PCT公布。 出版物WO90 / 03275 日本1990年04月5日。一种处理平版印刷版的方法,包括以下步骤:在烘烤步骤之前将预烘烤液体施加到板上,并且不是 发粘,使用寿命长,烘烤后不需要用水冲洗。 预烘焙液体包括一种或多种磺基琥珀酸盐或磺基琥珀酸盐,并且其数量足以在显影板上形成非水溶性烘烤涂层,其作为有效阻隔污染物质倾向于接触 与烘烤步骤中的板的显影区域,并且其与图像和非图像区域没有不利的反应并且允许板被烘烤,从而提高用于压制机的加工板的耐久性。 随后用碱性溶液除去烘烤的涂层。

    Intelligent component management for fire and other life safety systems
    5.
    发明申请
    Intelligent component management for fire and other life safety systems 有权
    消防和其他生命安全系统的智能部件管理

    公开(公告)号:US20050285730A1

    公开(公告)日:2005-12-29

    申请号:US10878475

    申请日:2004-06-28

    申请人: Gregory Turner

    发明人: Gregory Turner

    摘要: Automated systems and methods provide for enhanced management of components of fire safety systems. Components are identified which require action to ensure compliance with a schedule associated with the components. User and/or electronic output is generated that identifies components and required actions, such actions including inspections, functional testing, maintenance and calibration activities. A record of the identified components may be stored in a system log along with maintenance information. The system log may be reviewed against the schedule based on conformance to ordinances or maintenance requirements. Required actions may be annunciated for the identified components, and the system log may be updated to indicate actions performed on system components. Components may be identified that will require action within a predetermined timeframe and an alert or report may be generated for components that are not in compliance with their associated schedule.

    摘要翻译: 自动系统和方法提供了对消防安全系统组件进行增强的管理。 确定组件需要采取措施确保符合与组件相关的计划。 产生用户和/或电子输出,其识别组件和所需的动作,包括检查,功能测试,维护和校准活动。 所识别的组件的记录可以与维护信息一起存储在系统日志中。 系统日志可根据符合条例或维护要求的时间表进行审核。 可以为所识别的组件报告所需的操作,并且可以更新系统日志以指示对系统组件执行的操作。 可以识别将在预定时间范围内需要动作的组件,并且可以为不符合其相关调度的组件生成警报或报告。

    Imagable articles and compositions therefor
    6.
    发明授权
    Imagable articles and compositions therefor 失效
    可想象的文章和作品

    公开(公告)号:US06790588B2

    公开(公告)日:2004-09-14

    申请号:US10013141

    申请日:2001-12-10

    IPC分类号: G03F709

    摘要: Disclosed is a thermally sensitive imagable article and compositions therefor. The imagable article comprises a coating on a substrate, the coating comprising an amino acid or amide, and a compound capable of generating an acid upon heating. The coating optionally comprises a radiation absorbing compound. When imagewise exposed the coating has the property that exposed regions become relatively insoluble in a developer liquid whereas regions that have not been exposed remain relatively soluble in the developer and dissolve in the developer, leaving the exposed substrate in those regions.

    摘要翻译: 公开了一种热敏成像制品及其组合物。 可成像制品包括在基材上的涂层,所述涂层包含氨基酸或酰胺,以及加热时能够产生酸的化合物。 涂层任选地包含辐射吸收化合物。 当成像曝光涂层具有曝光区域变得相对不溶于显影液体的性质,而未曝光的区域保持相对可溶于显影剂并溶解在显影剂中,从而将曝光的基底留在那些区域。

    Pyrrolobenzodiazepine derivatives, compositions comprising the same and methods related thereto
    7.
    发明申请
    Pyrrolobenzodiazepine derivatives, compositions comprising the same and methods related thereto 失效
    吡咯并苯并二氮杂衍生物,包含其的组合物及其相关方法

    公开(公告)号:US20070072846A1

    公开(公告)日:2007-03-29

    申请号:US10576689

    申请日:2004-10-22

    IPC分类号: A61K31/551 C07D487/04

    CPC分类号: C07D487/04

    摘要: Disclosed are compounds of Formula (I) wherein X, Y, Ri-R7,T1, T2, Z, and p are as described herein; a pharmaceutical composition comprising a compound of Formula (I) and a carrier; a method of inhibiting growth of a cell, which method comprises administering in an amount effective to inhibit growth a compound of Formula (I); a method of treating cancer in a mammal, which method comprises administering in an amount effective to treat cancer a compound of Formula (I); a method of treating a viral, parasitic, or bacterial infection of a cell, which method comprises administering in an amount effective to treat a viral, parasitic, or bacterial infection a compound of Formula (I); and a method of preparing a compound of Formula (I) as described herein.

    摘要翻译: 公开了式(I)的化合物,其中X,Y,R 1 -R 7,T 1,T 2,Z和p是 如本文所述; 包含式(I)化合物和载体的药物组合物; 抑制细胞生长的方法,该方法包括以有效抑制生长的量施用式(I)化合物; 一种治疗哺乳动物癌症的方法,该方法包括以有效治疗癌症的量施用式(I)化合物; 治疗细胞的病毒,寄生或细菌感染的方法,所述方法包括以有效治疗病毒,寄生或细菌感染的量施用式(I)化合物; 和制备本文所述的式(I)化合物的方法。

    Dual reflector antenna and associated methods
    8.
    发明申请
    Dual reflector antenna and associated methods 有权
    双反射天线及相关方法

    公开(公告)号:US20060267851A1

    公开(公告)日:2006-11-30

    申请号:US11140836

    申请日:2005-05-31

    申请人: Gregory Turner

    发明人: Gregory Turner

    IPC分类号: H01Q13/00

    摘要: An antenna system includes an antenna feed aligned with a subreflector and a main reflector. The subreflector has a concave surface defining a vertex. A main reflector having a concave surface is aligned with the subreflector to define an antenna focal area at the vertex of the subreflector. The antenna feed may be a phased array or fixed antenna feed. The antenna system may further include a controller cooperating with the phased array antenna feed for beamsteering or beamforming. The controller may cooperate with the phased array antenna feed to define and steer multiple beams, at different frequencies, for example.

    摘要翻译: 天线系统包括与副反射器和主反射器对准的天线馈电。 子反射器具有限定顶点的凹面。 具有凹表面的主反射器与子反射器对准以在子反射器的顶点处限定天线焦点区域。 天线馈电可以是相控阵或固定天线馈电。 天线系统还可以包括与用于波束导向或波束成形的相控阵天线馈送器协作的控制器。 例如,控制器可以与相控阵天线馈电协作以限定和转向不同频率处的多个波束。