公开(公告)号：US4030640A

公开(公告)日：1977-06-21

申请号：US630278

申请日：1975-11-10

申请人： Paul S. Citrin ,  Frank Gurski

发明人： Paul S. Citrin ,  Frank Gurski

IPC分类号： B05C5/02 ,  B05C11/10 ,  G01F11/02 ,  G01F11/08 ,  B65D37/00

CPC分类号： B05C11/1047 ,  B05C5/0225 ,  G01F11/02 ,  G01F11/082 ,  G01F11/088 ,  B05C11/1034

摘要： A method and apparatus for dispensing small quantities of viscous materials in a reliable and accurately repeatable manner are described. A deformable tube which couples material in a reservoir to a discharge port is pinched by a valve at the same time the reservoir is pressurized. The material is dispensed in correspondence with the amount of reduction of the tube volume by the pinch valve. A simultaneous depressurizing of the material in the reservoir and the opening of the pinch valve enables a suck-back for a crisp cut-off of the material.

摘要翻译： 描述了以可靠且准确可重复的方式分配少量粘性材料的方法和装置。 将储存器中的材料连接到排出口的可变形管在阀被压力的同时被阀夹住。 与通过夹管阀减小管体积的量对应地分配材料。 储存器中的材料的同时减压和夹紧阀的打开使得能够使回吸物料清脆地切断。

公开(公告)号：US4358203A

公开(公告)日：1982-11-09

申请号：US214998

申请日：1980-12-10

申请人： Paul S. Citrin

发明人： Paul S. Citrin

IPC分类号： G01N21/75 ,  C12M1/34 ,  G01N21/25 ,  G01N35/00 ,  G01N35/02 ,  C12Q1/00 ,  G01D9/00

CPC分类号： G01N21/253 ,  G01N35/00

摘要： An apparatus is described with which a plurality of microbiological tests made in wells located in a pattern of rows on a tray can be conveniently analyzed and evaluated. A housing is formed with a tray analysis section and over which an arm is mounted to move from row to row. A plurality of manually activated signal generators are mounted on the arm, with the generators being aligned with a well in a row to enable the operator, upon identification of a particular well in a row as representative of analysis, to actuate the signal generator in registration therewith. The signals are representative of a score value and are recorded on score forms located in a test scoring section over which the arm moves with recording elements, also mounted on the arm. An elongated illuminator for a row of wells is described and which is conveniently adjusted to view selected test wells against different background lighting. The apparatus is particularly effective in color analysis of test wells by use of an apertured mask having color markings adjacent corresponding well locations.

摘要翻译： 描述了一种装置，其可以方便地分析和评估在位于托盘上的行中的孔中进行的多个微生物测试。 壳体形成有托盘分析部分，并且其上安装有臂以从一行到另一列移动。 多个手动激活的信号发生器安装在臂上，其中发生器与井中的井对准，以使得操作员能够在代表分析的一行中识别特定的井时，在登记中致动信号发生器 随之而来。 这些信号代表得分值，并且记录在位于测试记分部分中的分数表格上，手臂与记录元件一起移动，记录元件也安装在手臂上。 描述了用于一排井的细长的照明器，并且其被方便地调节以针对不同的背景照明来查看所选择的测试井。 该设备通过使用具有与相应的井位置相邻的颜色标记的孔径掩模在测试孔的颜色分析中特别有效。

公开(公告)号：US3982724A

公开(公告)日：1976-09-28

申请号：US568123

申请日：1975-04-14

申请人： Paul S. Citrin

发明人： Paul S. Citrin

IPC分类号： F16K7/06

CPC分类号： F16K7/06

摘要： A material dispenser using a deformable tube through which the flow of material is controlled is described. The deformable tube is selectively mounted to expose a pinch region to a pressure element having a predetermined shape. The deformable tube is selectively supported to enable precise control over tube constriction for accurate material flow control. A micrometer stop is conveniently mounted to regulate the size of the tube restriction. Automatic and repeated actuation of the dispenser is obtained by locating the pressure element as a piston in a cylinder. Various deformable tube embodiments are described to reduce tube wall stresses for longer operating life and enable both positive closure and opening of the deformable tube.

摘要翻译： 描述了使用可变形管的材料分配器，通过该可变形管控制材料流动。 可变形管被选择性地安装以将夹紧区域暴露于具有预定形状的压力元件。 选择性地支撑可变形管，以便精确地控制管收缩以获得精确的物料流控制。 方便地安装千分尺，以调节管限制的尺寸。 通过将作为活塞的压力元件定位在气缸中来获得分配器的自动和重复致动。 描述了各种可变形管实施例以减小管壁应力以延长使用寿命并且能够使可变形管的正闭合和打开。

公开(公告)号：US4342407A

公开(公告)日：1982-08-03

申请号：US173628

申请日：1980-07-30

申请人： Paul S. Citrin

发明人： Paul S. Citrin

IPC分类号： G01N35/10 ,  B65B3/06

CPC分类号： G01N35/10

摘要： Apparatus for control of multiple liquid dispensing providing accurate metering, close spacing of the fluids dispensed and rapid cycling. One embodiment contemplates transferring liquids from a multiplicity of containers to a corresponding multiplicity of wells in a microtitration test tray, and includes a multiplicity of resilient conduits extending from the containers into a common pinch type valve that clamps the ends of the conduits closed or permits them to open for liquid discharge.

摘要翻译： 用于控制多个液体分配的装置，其提供准确的计量，分配的流体的紧密间隔和快速循环。 一个实施例设想将液体从多个容器转移到微量滴定试验盘中的相应多个孔，并且包括多个弹性管道，其从容器延伸到公共的夹紧型阀门中，该管道将管道的端部封闭或允许 打开液体排放。

公开(公告)号：US4022207A

公开(公告)日：1977-05-10

申请号：US670358

申请日：1976-03-25

申请人： Paul S. Citrin

发明人： Paul S. Citrin

IPC分类号： A61M5/20 ,  A61M5/315 ,  A61M5/00

CPC分类号： A61M5/20 ,  A61M5/31556 ,  A61M5/31578 ,  A61M5/31595

摘要： An actuator for a syringe is disclosed with which precise liquid quantities can be dispensed in an accurately repeatable manner with single-hand control. The actuator is formed with a main body shaped to support a syringe whose plunger is moved by a plunger actuator. A reciprocating finger actuatable pusher is mounted with the plunger actuator to the main body and a ratchet mechanism operative between the plunger actuator and the pusher provides discrete motions of the plunger actuator. The main components of the syringe actuator are formed of extruded material and shaped in cross section to conveniently fit together. A back motion inhibitor is employed in the form of a fibrous material capable of restraining reverse movement of the plunger actuator while allowing unobstructed operative movement thereof.

摘要翻译： 公开了一种用于注射器的致动器，其中可以以单手控制以精确可重复的方式分配精确的液体量。 致动器形成有主体，该主体成形为支撑柱塞由柱塞致动器移动的注射器。 往复式手指致动推动器安装有柱塞致动器到主体，并且在柱塞致动器和推动器之间操作的棘轮机构提供柱塞致动器的离散运动。 注射器致动器的主要部件由挤压材料形成并且成形为横截面以方便地配合在一起。 反向运动抑制剂以纤维材料的形式使用，其能够限制柱塞致动器的反向运动，同时允许其无阻碍的操作运动。

公开(公告)号：US4589870A

公开(公告)日：1986-05-20

申请号：US581801

申请日：1984-02-21

申请人： Paul S. Citrin ,  Nelson F. Murcko

发明人： Paul S. Citrin ,  Nelson F. Murcko

IPC分类号： G05G7/00 ,  B05C11/10 ,  F04B9/14 ,  A61M5/315

CPC分类号： B05C17/0126 ,  B05C11/10

摘要： A manually operated actuator is described with which small incremental motions of a rod are obtained to advance a piston of a prefilled syringe. The device employs a reciprocally actuated drive element with a hole through which the rod passes freely when the drive element is in a release position. When the drive element is pivoted to a rod engaging position a pair of edges formed by the hole engage the rod and advance it an increment depending upon the amount of linear movement of the drive element. A back-up inhibitor is employed to prevent the rod from moving back when the drive element is returned to a release position. The back-up inhibitor is syringe responsive by employing a mechanism which causes engagement of the rod by the inhibitor when a syringe is attached to the actuator housing. A syringe with specially adapted flanges is described for use with the actuator.

摘要翻译： 描述了一种手动操作的致动器，其中获得杆的小的增量运动以推动预填充注射器的活塞。 该装置采用具有孔的往复致动的驱动元件，当驱动元件处于释放位置时，杆通过该孔自由通过。 当驱动元件枢转到杆接合位置时，由孔形成的一对边缘与杆接合并且根据驱动元件的线性运动量将其增加。 当驱动元件返回到释放位置时，使用备用抑制器来防止杆返回。 备用抑制剂是通过使用当将注射器附接到致动器壳体时通过抑制剂使杆接合的机构的注射器响应。 描述了具有特殊适配法兰的注射器，用于执行机构。

公开(公告)号：US4187724A

公开(公告)日：1980-02-12

申请号：US948486

申请日：1978-10-04

申请人： Paul S. Citrin

发明人： Paul S. Citrin

IPC分类号： B01L3/02

CPC分类号： B01L3/0275

摘要： A replaceable pipette tip is described which forms a tight sealing engagement with the working end of a pipette. In one embodiment for a pipette tip a cam surface is provided to enable a slight tip rotation when the working end of a pipette is inserted in the tip. A particularly effective and reliable seal is obtained when a pipette tip having integrally molded ring seals and a cam surface is employed with a pipette working end having a resilient insert located to form an effective seal with the molded rings.

摘要翻译： 描述了与移液管的工作端形成紧密密封接合的可更换的吸头。 在移液管尖端的一个实施例中，提供凸轮表面以使得当移液管的工作端插入尖端时能够进行轻微的尖端旋转。 当采用具有整体模制的环形密封件和凸轮表面的移液管尖端时，获得特别有效和可靠的密封，其中移液管工作端具有定位成与模制环形成有效密封的弹性插入件。

公开(公告)号：US4369665A

公开(公告)日：1983-01-25

申请号：US33044

申请日：1979-04-25

申请人： Paul S. Citrin

发明人： Paul S. Citrin

IPC分类号： B01L3/02

CPC分类号： B01L3/0227

摘要： An automatic pipette is described which can be manually held yet provides a highly accurate instrument capable of precise handling of very small liquid samples. A main housing is provided sized to be conveniently held in the hand of an operator. The housing encloses a displacement mechanism of a size selected to provide a highly accurate handling of small liquid samples as well as a motor drive, control circuit and a power source. The control circuit provides a precise control over rate of intake and dispense and is selected to reduce power demand while maintaining safety features to simplify operator manual control. A technique is described to enhance engagement between the pipette and a replaceable tip for low air leakage and attendant enhanced take-up accuracy, as well as provide an integral method for gentle tip removal after contamination. A dilution pipette is described to provide a highly accurate dilution of small liquid samples.

摘要翻译： 描述了可以手动保持的自动移液器，但是提供了能够精确处理非常小的液体样品的高精度仪器。 主壳体的尺寸被设计成方便地保持在操作者的手中。 壳体包围一个尺寸选择的位移机构，以提供对小液体样品以及电机驱动，控制电路和电源的高精度处理。 控制电路提供了对进气和分配速率的精确控制，并且被选择以减少功率需求，同时保持安全特征以简化操作者手动控制。 描述了一种技术来增强移液器与可更换的尖端之间的接合，以减少空气泄漏和提高吸收精度，并提供一种完整的方法，以便在污染后缓和尖端去除。 描述稀释移液管以提供对小液体样品的高精度稀释。

公开(公告)号：US4176671A

公开(公告)日：1979-12-04

申请号：US879532

申请日：1978-02-21

申请人： Paul S. Citrin

发明人： Paul S. Citrin

IPC分类号： F16K7/02 ,  F16K31/02

CPC分类号： F16K7/02 ,  F16K31/02 ,  Y10T137/0318 ,  Y10T137/86421 ,  Y10T137/86461

摘要： A valve is described capable of rapid actuations. The valve includes a drive element disposed to pinchingly engage a collapsible tube at a high reciprocating speed. A follower is disposed on the other side of the tube and effectively coupled for reciprocation and cooperative movement with the drive element to maintain the tube pinched off. Control means and holder are provided to open the valve by retaining the follower at just that time when the follower is at a favorable reciprocated position so that further reciprocation by the drive element can open the tube. A normally open valve is also described and a control for operation of a plurality of valves is disclosed.

摘要翻译： 描述能够快速启动的阀。 阀包括设置成以高往复速度夹紧地接合可折叠管的驱动元件。 跟随器设置在管的另一侧上并且有效地联接以便与驱动元件往复运动和协同运动以保持管夹紧。 控制装置和保持器设置成通过在随动件处于良好的往复运动位置的同时保持随动件来打开阀，使得由驱动元件进一步的往复运动可以打开管。 还描述了常开的阀，并且公开了用于多个阀的操作的控制。

公开(公告)号：USD246115S

公开(公告)日：1977-10-18

申请号：US670163

申请日：1976-03-25

申请人： Paul S. Citrin

设计人： Paul S. Citrin