摘要:
The invention is to provide a method for fabricating a patterned chip with adjustable surface including of a basic layer, an insulating layer and a layer of biomolecules or cells. The method comprises of the following steps: pre-patterning a basic layer by photolithography; coating the pre-patterned basic layer with an insulating layer, the insulating layer is placed in solution containing biomolecules or cells with external voltage applied to the insulating layer. In addition, two steps—fabricating an pattern on the insulating layer matching the pattern of the basic layer by photolithography and treating the patterned insulating surface with chemical, physical or plasma surface process treatment—can be further followed by the step of pre-patterning a basic layer by photolithography, then proceeding the remaining steps.
摘要:
A microfluidic device that includes one or more microchannels configured to transport fluid, and one or more microchambers configured to receive the fluid, wherein each of the one or more microchannels is coupled in fluid communication to at least one of the one or more microchambers. The microfluidic device also includes a first set of electrodes, each of the electrodes electrically coupled to one of the one or more microchannels, and configured to selectively apply an adjustable voltage to the respective microchannel to cause the fluid in that microchannel to flow. The microfluidic device further includes a second set of electrodes, where each of the electrodes in the second set of electrodes is electrically coupled to corresponding microchambers and configured to apply an adjustable voltage to the corresponding microchambers to direct flowing fluid into those corresponding microchambers from the microchannels to which those corresponding microchambers are coupled.