Patterned chip with adjustable surface and method for manufacturing the same
    1.
    发明申请
    Patterned chip with adjustable surface and method for manufacturing the same 审中-公开
    具有可调表面的图案化芯片及其制造方法

    公开(公告)号:US20070235333A1

    公开(公告)日:2007-10-11

    申请号:US11400507

    申请日:2006-04-07

    IPC分类号: C07K1/26

    摘要: The invention is to provide a method for fabricating a patterned chip with adjustable surface including of a basic layer, an insulating layer and a layer of biomolecules or cells. The method comprises of the following steps: pre-patterning a basic layer by photolithography; coating the pre-patterned basic layer with an insulating layer, the insulating layer is placed in solution containing biomolecules or cells with external voltage applied to the insulating layer. In addition, two steps—fabricating an pattern on the insulating layer matching the pattern of the basic layer by photolithography and treating the patterned insulating surface with chemical, physical or plasma surface process treatment—can be further followed by the step of pre-patterning a basic layer by photolithography, then proceeding the remaining steps.

    摘要翻译: 本发明提供一种用于制造具有包括基本层,绝缘层和生物分子或细胞层的具有可调表面的图案化芯片的方法。 该方法包括以下步骤:通过光刻预先图案化基底层; 用绝缘层涂覆预图案化的基底层,将绝缘层放置在含有施加到绝缘层的外部电压的生物分子或电池的溶液中。 另外,通过光刻法在匹配基底层的图案的绝缘层上制造图案并用化学,物理或等离子体表面处理处理来处理图案化绝缘表面的两个步骤可以进一步遵循以下步骤:预图案化 基础层通过光刻,然后进行剩余的步骤。

    Electrically controlled addressable multi-dimensional microfluidic device and method
    2.
    发明申请
    Electrically controlled addressable multi-dimensional microfluidic device and method 审中-公开
    电控可寻址多维微流体装置及方法

    公开(公告)号:US20070095407A1

    公开(公告)日:2007-05-03

    申请号:US11262495

    申请日:2005-10-28

    IPC分类号: F16K11/20

    摘要: A microfluidic device that includes one or more microchannels configured to transport fluid, and one or more microchambers configured to receive the fluid, wherein each of the one or more microchannels is coupled in fluid communication to at least one of the one or more microchambers. The microfluidic device also includes a first set of electrodes, each of the electrodes electrically coupled to one of the one or more microchannels, and configured to selectively apply an adjustable voltage to the respective microchannel to cause the fluid in that microchannel to flow. The microfluidic device further includes a second set of electrodes, where each of the electrodes in the second set of electrodes is electrically coupled to corresponding microchambers and configured to apply an adjustable voltage to the corresponding microchambers to direct flowing fluid into those corresponding microchambers from the microchannels to which those corresponding microchambers are coupled.

    摘要翻译: 一种微流体装置,其包括构造成输送流体的一个或多个微通道,以及被配置为接收流体的一个或多个微室,其中所述一个或多个微通道中的每一个与所述一个或多个微室中的至少一个流体连通地耦合。 微流体装置还包括第一组电极,每个电极电耦合到一个或多个微通道之一,并且被配置为选择性地将可调电压施加到相应的微通道以使该微通道中的流体流动。 微流体装置还包括第二组电极,其中第二组电极中的每个电极电耦合到对应的微室,并且被配置为向相应的微室施加可调节的电压,以将流动流体引导到来自微通道的相应微室中 那些相应的微室耦合到这些微室。