摘要:
A dry powder inhaler for pulmonary or nasal use, comprising at least an inhaler body and a cartridge with one or more compartments each containing one dose of a drug. The compartment has holes to admit air and holes to deliver powder, which, in use, communicate with an inhalation channel in the inhaler body. To prevent the powder from leaking through the compartment holes before use, the air admission holes are of reduced dimension, thereby blocking or hindering powder exit under the force of gravity. When the cartridge is inserted inside the inhaler body, all its holes can be blocked. By sliding the cartridge in relation to the body until the inhalation position is reached, the holes come into in fluid communication with one another and with the inhalation channel, thereby allowing a flow of air to disperse and entrain the dose through the mouthpiece. Five embodiments are disclosed.
摘要:
Apparatus for orienting elongate objects, for example capsules of medicament, comprises a passage for receiving an individual capsule in a preferred orientation, a container for holding a bulk supply of capsules, and a ramp surface which directs a capsule towards the passage when the device is positioned such that the passage extends vertically downwardly from the container. It has been found that by appropriate choice of ramp angle, passage diameter and container diameter there is a high probability that a single capsule will be loaded into the dispensing passage when the apparatus is inverted to place the dispensing passage below the bulk supply. The apparatus is particularly useful in a dry medicament dispensing apparatus comprising, in addition to the orienting apparatus, a chamber for receiving capsules from the dispensing passage, means for piercing the ends of the capsule, and a mouthpiece for drawing air through the capsule and to entrain the medicament.
摘要:
A new inhalation device, which during operation causes an aerosol to be formed inside a chamber such as a capsule (4) which occludes one end (3) of the inhalation tube (1), the capsule having holes at its extremities (7,8) which admit airflow. The airflow causes the powder contained inside the capsule to be surprisingly transported to the capsule extremity contrary to the direction of inhalation, that is towards the air entry holes in the capsule, and then to form an aerosol until all powder has been removed from the capsule or chamber through the tube (1), the during of inhalation being chiefly regulated by the size and proportion of the capsule holes. The tube (1) has air inlets downstream of the capsule to permit a balanced airflow that will transport the finely suspended powder into the lungs, maximizing the fraction of medicament deposited therein.
摘要:
A dry powder inhaler for pulmonary or nasal use, comprising at least an inhaler body and a cartridge with one or more compartments each containing one dose of a drug. The compartment has holes to admit air and holes to deliver powder, which, in use, communicate with an inhalation channel in the inhaler body. To prevent the powder from leaking through the compartment holes before use, the air admission holes are of reduced dimension, thereby blocking or hindering powder exit under the force of gravity. When the cartridge is inserted inside the inhaler body, all its holes can be blocked. By sliding the cartridge in relation to the body until the inhalation position is reached, the holes come into in fluid communication with one another and with the inhalation channel, thereby allowing a flow of air to disperse and entrain the dose through the mouthpiece. Five embodiments are disclosed.
摘要:
An inhaler (1) for dispensing doses of medicament from a container under user activation said inhaling which comprises a body (7) which includes a mouthpiece (5) through which the medicament is dispensed and a cap (2) which can be place in a position to substantially occlude the mouthpiece (5). The cap (2) is attached to said body (7) by a strap (3) which pivots from said body (7), said cap (2) being arranged to slide on the strap (3) such that the cap (2) must translate away from the mouthpiece (5) prior to the pivoting of the strap (3).
摘要:
An inhaler (1) for dispensing doses of medicament from a container under user activation said inhaling which comprises a body (7) which includes a mouthpiece (5) through which the medicament is dispensed and a cap (2) which can be place in a position to substantially occlude the mouthpiece (5). The cap (2) is attached to said body (7) by a strap (3) which pivots from said body (7), said cap (2) being arranged to slide on the strap (3) such that the cap (2) must translate away from the mouthpiece (5) prior to the pivoting of the strap (3).