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公开(公告)号：US10543267B2
公开(公告)日：2020-01-28
申请号：US16196150
申请日：2018-11-20
Applicant: PFIZER INC.
Inventor： Kathrin Ute Jansen , Annaliesa Sybil Anderson , Judith Absalon , Jose Miguel Aste-Amezaga , Johannes Frederik Beeslaar , David Cooper , John Erwin Farley , Leah Diane Fletcher , Shannon Lea Harris , Thomas Richard Jones , Isis Kanevsky , Lakshmi Khandke , Paul Liberator , John Lance Perez , Lynn Marie Phelan , Gary Warren Zlotnick
IPC: A61K39/095 , A61K31/7028 , A61K47/10 , A61K47/18 , C07K14/22 , C07K16/12 , A61K47/26 , A61K47/64 , A61P31/00
Abstract: In one aspect, the invention relates to a composition including a factor H binding protein (fHBP) and a Neisseria meningitidis non-serogroup B capsular polysaccharide. The invention further relates to uses of a composition that includes fHBP, such as, for example, uses to elicit an immune response against N. meningitidis serogroup B strains and non-serogroup B strains. The compositions and methods described herein are directed to administration in humans, including adults, adolescents, toddlers, and infants.
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2.发明公开公开(公告)号：US20240189410A1
公开(公告)日：2024-06-13
申请号：US18535116
申请日：2023-12-11
Applicant: Pfizer Inc.
Inventor： Annaliesa Sybil Anderson , Marina A. Gonzalez-Garis , Lei Hu , Isis Kanevsky , Paul Arthur Liberator , Justin Keith Moran , Lynn Marie Phelan , Michael William Pride , Shuai Shi , Naveen Surendran
CPC classification number: A61K39/08 , A61K39/39 , A61P31/04 , A61K2039/55561
Abstract: The present invention relates to immunogenic compositions that comprise a Clostridioides difficile toxoid A and/or a C. difficile toxoid B, and an adjuvant, and methods of use thereof. The present invention further relate to a methods for eliciting an enhanced immune response in a human against a C. difficile infection. The methods include administering to the human an effective dose of an immunogenic composition, which includes a C. difficile toxoid and an adjuvant, wherein the composition is administered two times.
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公开(公告)号：US20230414737A1
公开(公告)日：2023-12-28
申请号：US18343968
申请日：2023-06-29
Applicant: PFIZER INC.
Inventor： Kathrin Ute Jansen , Annaliesa Sybil Anderson , Judith Absalon , Jose Miguel Aste-Amezaga , Johannes Frederik Beeslaar , David Cooper , John Erwin Farley , Leah Diane Fletcher , Shannon Lea Harris , Thomas Richard Jones , Isis Kanevsky , Lakshmi Khandke , Paul Liberator , John Lance Perez , Lynn Marie Phelan , Gary Warren Zlotnick
IPC: A61K39/095 , C07K14/22 , C07K16/12 , A61K47/18 , A61K47/10 , A61K47/26 , A61K31/7028 , A61K47/64 , A61P31/00 , A61K39/12
CPC classification number: A61K39/095 , C07K14/22 , C07K16/1217 , A61K47/183 , A61K47/10 , A61K47/26 , A61K31/7028 , A61K47/6415 , A61K47/646 , A61P31/00 , A61K39/12 , A61K2039/545
Abstract: In one aspect, the invention relates to a composition including a factor H binding protein (fHBP) and a Neisseria meningitidis non-serogroup B capsular polysaccharide. The invention further relates to uses of a composition that includes fHBP, such as, for example, uses to elicit an immune response against N. meningitidis serogroup B strains and non-serogroup B strains. The compositions and methods described herein are directed to administration in humans, including adults, adolescents, toddlers, and infants.
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公开(公告)号：US20200164056A1
公开(公告)日：2020-05-28
申请号：US16704701
申请日：2019-12-05
Applicant: PFIZER INC.
Inventor： Kathrin Ute Jansen , Annaliesa Sybil Anderson , Judith Absalon , Jose Miguel Aste-Amezaga , Johannes Frederik Beeslaar , David Cooper , John Erwin Farley , Leah Diane Fletcher , Shannon Lea Harris , Thomas Richard Jones , Isis Kanevsky , Lakshmi Khandke , Paul Liberator , John Lance Perez , Lynn Marie Phelan , Gary Warren Zlotnick
IPC: A61K39/095 , A61P31/00 , A61K47/64 , A61K31/7028 , A61K47/26 , A61K47/10 , A61K47/18 , C07K16/12 , C07K14/22 , A61K39/12
Abstract: In one aspect, the invention relates to a composition including a factor H binding protein (fHBP) and a Neisseria meningitidis non-serogroup B capsular polysaccharide. The invention further relates to uses of a composition that includes fHBP, such as, for example, uses to elicit an immune response against N. meningitidis serogroup B strains and non-serogroup B strains. The compositions and methods described herein are directed to administration in humans, including adults, adolescents, toddlers, and infants.
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公开(公告)号：US20190231861A1
公开(公告)日：2019-08-01
申请号：US16196150
申请日：2018-11-20
Applicant: PFIZER INC.
Inventor： Kathrin Ute Jansen , Annaliesa Sybil Anderson , Judith Absalon , Jose Miguel Aste-Amezaga , Johannes Frederik Beeslaar , David Cooper , John Erwin Farley , Leah Diane Fletcher , Shannon Lea Harris , Thomas Richard Jones , Isis Kanevsky , Lakshmi Khandke , Paul Liberator , John Lance Perez , Lynn Marie Phelan , Gary Warren Zlotnick
IPC: A61K39/095 , A61K31/7028 , C07K14/22 , A61K47/26 , A61K47/64 , A61K47/18 , C07K16/12 , A61P31/00 , A61K47/10
Abstract: In one aspect, the invention relates to a composition including a factor H binding protein (fHBP) and a Neisseria meningitidis non-serogroup B capsular polysaccharide. The invention further relates to uses of a composition that includes fHBP, such as, for example, uses to elicit an immune response against N. meningitidis serogroup B strains and non-serogroup B strains. The compositions and methods described herein are directed to administration in humans, including adults, adolescents, toddlers, and infants.
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Patent Agency Ranking
公开(公告)号：US20180214532A1
公开(公告)日：2018-08-02
申请号：US15883334
申请日：2018-01-30
Applicant: PFIZER INC.
Inventor： Kathrin Ute Jansen , Annaliesa Sybil Anderson , Judith Absalon , Jose Miguel Aste-Amezaga , Johannes Frederik Beeslaar , David Cooper , John Erwin Farley , Leah Diane Fletcher , Shannon Lea Harris , Thomas Richard Jones , Isis Kanevsky , Lakshmi Khandke , Paul Liberator , John Lance Perez , Lynn Marie Phelan , Gary Warren Zlotnick
IPC: A61K39/095 , C07K14/22 , C07K16/12 , A61K31/7028 , A61K47/10 , A61K47/26 , A61K47/18
CPC classification number: A61K39/095 , A61K31/7028 , A61K47/10 , A61K47/183 , A61K47/26 , A61K47/6415 , A61K47/646 , A61P31/00 , C07K14/22 , C07K16/1217
Abstract: In one aspect, the invention relates to a composition including a factor H binding protein (fHBP) and a Neisseria meningitidis non-serogroup B capsular polysaccharide. The invention further relates to uses of a composition that includes fHBP, such as, for example, uses to elicit an immune response against N. meningitidis serogroup B strains and non-serogroup B strains. The compositions and methods described herein are directed to administration in humans, including adults, adolescents, toddlers, and infants.
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公开(公告)号：US20240252612A1
公开(公告)日：2024-08-01
申请号：US18533167
申请日：2023-12-07
Applicant: PFIZER INC.
Inventor： Fanyu Meng , Lynn Marie Phelan , Pirada Suphaphiphat Allen , Nicholas Luksha , Bakul Subodh Bhatnagar , Ramin Darvari , Jayesh Vijay Sonje , Serguei Tchessalov , Advait Vijay Badkar , Michael David Bruchsaler , Wouter Joris Knapen , Parag Kolhe , Marjoh Anne Nauta , Naomi Sasha Ramesar , Vincent Jurgen L. Van Deyck , Bert Van Meervenne , Thijs Vanslembrouck , Sarah Elizabeth Weiser
CPC classification number: A61K39/145 , A61K9/0019 , A61K9/146 , A61K9/19 , A61K47/26 , A61K2039/55555 , A61K2039/575
Abstract: The present disclosure relates to compositions comprising RNA molecules encoding an antigen derived from influenza, wherein the RNA may be formulated in a lipid nanoparticle (LNP), and wherein the composition further includes a polypeptide antigen derived from respiratory syncytial virus (RSV) and/or RNA molecules encoding an antigen derived from RSV, wherein the RSV RNA may be may be formulated in an LNP. The present disclosure further relates to the use of the RNA molecules, RNA-LNPs and compositions for the prevention of influenza and RSV infection-induced illness.
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公开(公告)号：US11730800B2
公开(公告)日：2023-08-22
申请号：US17024618
申请日：2020-09-17
Applicant: PFIZER INC.
Inventor： Kathrin Ute Jansen , Annaliesa Sybil Anderson , Judith Absalon , Jose Miguel Aste-Amezaga , Johannes Frederik Beeslaar , David Cooper , John Erwin Farley , Leah Diane Fletcher , Shannon Lea Harris , Thomas Richard Jones , Isis Kanevsky , Lakshmi Khandke , Paul Liberator , John Lance Perez , Lynn Marie Phelan , Gary Warren Zlotnick
IPC: A61K39/095 , A61K47/64 , C07K14/22 , C07K16/12 , A61K39/00 , A61K47/18 , A61K47/10 , A61K47/26 , A61K31/7028 , A61P31/00 , A61K39/12
CPC classification number: A61K39/095 , A61K31/7028 , A61K39/12 , A61K47/10 , A61K47/183 , A61K47/26 , A61K47/646 , A61K47/6415 , A61P31/00 , C07K14/22 , C07K16/1217 , A61K2039/545 , A61K2039/55 , A61K2039/55505 , A61K2039/6037 , A61K2039/70 , C12N2770/32434
Abstract: In one aspect, the invention relates to a composition including a factor H binding protein (fHBP) and a Neisseria meningitidis non-serogroup B capsular polysaccharide. The invention further relates to uses of a composition that includes fHBP, such as, for example, uses to elicit an immune response against N. meningitidis serogroup B strains and non-serogroup B strains. The compositions and methods described herein are directed to administration in humans, including adults, adolescents, toddlers, and infants.
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公开(公告)号：US10813989B2
公开(公告)日：2020-10-27
申请号：US16704701
申请日：2019-12-05
Applicant: PFIZER INC.
Inventor： Kathrin Ute Jansen , Annaliesa Sybil Anderson , Judith Absalon , Jose Miguel Aste-Amezaga , Johannes Frederik Beeslaar , David Cooper , John Erwin Farley , Leah Diane Fletcher , Shannon Lea Harris , Thomas Richard Jones , Isis Kanevsky , Lakshmi Khandke , Paul Liberator , John Lance Perez , Lynn Marie Phelan , Gary Warren Zlotnick
IPC: A61K39/095 , A61K31/7028 , A61K47/10 , A61K47/18 , C07K14/22 , C07K16/12 , A61K47/26 , A61K47/64 , A61P31/00 , A61K39/12 , A61K39/00
Abstract: In one aspect, the invention relates to a composition including a factor H binding protein (fHBP) and a Neisseria meningitidis non-serogroup B capsular polysaccharide. The invention further relates to uses of a composition that includes fHBP, such as, for example, uses to elicit an immune response against N. meningitidis serogroup B strains and non-serogroup B strains. The compositions and methods described herein are directed to administration in humans, including adults, adolescents, toddlers, and infants.
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公开(公告)号：US10183070B2
公开(公告)日：2019-01-22
申请号：US15883334
申请日：2018-01-30
Applicant: PFIZER INC.
Inventor： Kathrin Ute Jansen , Annaliesa Sybil Anderson , Judith Absalon , Jose Miguel Aste-Amezaga , Johannes Frederik Beeslaar , David Cooper , John Erwin Farley , Leah Diane Fletcher , Shannon Lea Harris , Thomas Richard Jones , Isis Kanevsky , Lakshmi Khandke , Paul Liberator , John Lance Perez , Lynn Marie Phelan , Gary Warren Zlotnick
IPC: A61K39/095 , A61K31/7028 , A61K47/10 , A61K47/18 , C07K14/22 , C07K16/12 , A61K47/26 , A61K47/64 , A61P31/00
Abstract: In one aspect, the invention relates to a composition including a factor H binding protein (fHBP) and a Neisseria meningitidis non-serogroup B capsular polysaccharide. The invention further relates to uses of a composition that includes fHBP, such as, for example, uses to elicit an immune response against N. meningitidis serogroup B strains and non-serogroup B strains. The compositions and methods described herein are directed to administration in humans, including adults, adolescents, toddlers, and infants.
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