公开(公告)号：US08863749B2

公开(公告)日：2014-10-21

申请号：US13279152

申请日：2011-10-21

申请人： Philip Gooding ,  Christine Beltran ,  Jonathan Talamo

发明人： Philip Gooding ,  Christine Beltran ,  Jonathan Talamo

IPC分类号： A61B19/00 ,  A61F9/009 ,  A61F9/008

CPC分类号： A61F9/009 ,  A61B18/20 ,  A61F9/00812 ,  A61F9/00827 ,  A61F2009/0052 ,  A61F2009/00844 ,  A61F2009/00853 ,  A61F2009/00865 ,  A61F2009/0087 ,  A61F2009/00872 ,  A61F2009/00887 ,  A61F2009/00889

摘要： One embodiment is directed to a method for interfacing an ophthalmic intervention system with an eye of a patient, comprising: placing a patient interface assembly comprising a housing, an optical lens coupled to the housing, and an eye engagement assembly coupled to the housing, the eye engagement assembly comprising an inner seal and an outer seal, into contact with the eye of the patient by sealably engaging the eye with the inner and outer seals in a vacuum zone defined between the inner and outer seals; applying a vacuum load between the inner and outer seals to engage the eye using the vacuum load; and physically limiting an amount of distension of the eye in the vacuum zone.

摘要翻译： 一个实施例涉及一种用于将眼科干预系统与患者的眼睛接合的方法，包括：放置患者接口组件，其包括壳体，联接到所述壳体的光学透镜以及耦合到所述壳体的眼睛接合组件， 眼睛接合组件包括内部密封件和外部密封件，其通过在限定在内部和外部密封件之间的真空区域中将眼睛与内部密封件和外部密封件密封地接合而与患者的眼睛接触; 在内密封件和外密封件之间施加真空负载以使用真空负载接合眼睛; 并在物理上限制眼睛在真空区中的膨胀量。

公开(公告)号：US09044302B2

公开(公告)日：2015-06-02

申请号：US13279126

申请日：2011-10-21

申请人： Philip Gooding ,  Christine Beltran

发明人： Philip Gooding ,  Christine Beltran

IPC分类号： A61B13/00 ,  A61B18/18 ,  A61F9/008 ,  A61B3/14 ,  A61B5/00 ,  A61B18/20 ,  A61B8/10

CPC分类号： A61F9/009 ,  A61B3/14 ,  A61B5/0059 ,  A61B8/10 ,  A61B18/201 ,  A61F9/00802 ,  A61F9/00825 ,  A61F2009/0087 ,  A61F2009/00887 ,  A61F2009/00889 ,  A61F2009/00897

摘要： One embodiment is directed to a patient interface system for ophthalmic intervention on an eye of a patient, comprising: a housing; an optical lens coupled to the housing and having a focal axis; a eye surface engagement assembly coupled to the housing and comprising an inner seal having an inner seal diameter and being configured to circumferentially engage the eye, an outer seal having an outer seal diameter and being configured to circumferentially engage the eye, and a tissue migration bolster structure configured to be positioned circumferentially between the inner and outer circumferential seals and to prevent migration of tissue of the eye toward the eye surface engagement assembly when a vacuum load is applied within the assembly to cause vacuum engagement of the inner and outer seals against the eye.

摘要翻译： 一个实施例涉及用于患者眼睛上的眼科干预的患者接口系统，包括：壳体; 耦合到壳体并具有焦轴的光学透镜; 眼表面接合组件，其联接到所述壳体并且包括内密封件，所述内密封件具有内密封件直径并且构造成周向接合所述眼睛;外密封件，其具有外密封件直径并且构造成周向接合所述眼部;以及组织移植垫 结构构造成周向地定位在内外周密封之间并且当在组件内施加真空负载以防止内密封件和外密封件与眼睛的真空接合时，防止眼睛组织向眼表面接合组件移动 。

公开(公告)号：US20130103014A1

公开(公告)日：2013-04-25

申请号：US13279155

申请日：2011-10-21

申请人： Philip Gooding ,  Michael Wiltberger

发明人： Philip Gooding ,  Michael Wiltberger

IPC分类号： A61F9/01 ,  A61F9/008 ,  A61B3/10

CPC分类号： A61F9/00825 ,  A61B3/0008 ,  A61B3/0025 ,  A61B3/102 ,  A61B3/14 ,  A61B90/39 ,  A61B2090/3937 ,  A61B2090/3979 ,  A61B2090/3983 ,  A61F9/00814 ,  A61F9/00817 ,  A61F9/0084 ,  A61F9/009 ,  A61F2009/00851 ,  A61F2009/0087 ,  A61F2009/00887 ,  A61F2009/00897

摘要： An ophthalmic system may comprise an imaging device having a field of view oriented toward the eye of the patient; a patient interface housing defining a passage therethrough, having a distal end coupled to one or more seals configured to be directly engaged with one or more surfaces of the eye of the patient, and wherein the proximal end is configured to be coupled to the patient workstation such that at least a portion of the field of view of the imaging device passes through the passage; and two or more registration fiducials coupled to the patient interface housing in a predetermined geometric configuration relative to the patient interface housing within the field of view of the imaging device such that they may be imaged by the imaging device in reference to predetermined geometric markers on the eye of the patient which may also be imaged by the imaging device.

摘要翻译： 眼科系统可以包括具有朝向患者眼睛的视野的成像装置; 患者接口壳体限定穿过其中的通道，其具有联接到构造成与患者的眼睛的一个或多个表面直接接合的一个或多个密封件的远端，并且其中近端构造成联接到患者工作站 使得成像装置的视场的至少一部分通过通道; 以及两个或更多个配准基准，其以相对于成像装置的视野范围内的患者接口壳体的预定几何构型联接到患者接口壳体，使得它们可以通过成像装置参考所述成像装置上的预定几何标记进行成像 也可以由成像装置成像的患者的眼睛。

公开(公告)号：US20130102922A1

公开(公告)日：2013-04-25

申请号：US13279126

申请日：2011-10-21

申请人： Philip Gooding

发明人： Philip Gooding

IPC分类号： A61B13/00

CPC分类号： A61F9/009 ,  A61B3/14 ,  A61B5/0059 ,  A61B8/10 ,  A61B18/201 ,  A61F9/00802 ,  A61F9/00825 ,  A61F2009/0087 ,  A61F2009/00887 ,  A61F2009/00889 ,  A61F2009/00897

摘要： One embodiment is directed to a patient interface system for ophthalmic intervention on an eye of a patient, comprising: a housing; an optical lens coupled to the housing and having a focal axis; a eye surface engagement assembly coupled to the housing and comprising an inner seal having an inner seal diameter and being configured to circumferentially engage the eye, an outer seal having an outer seal diameter and being configured to circumferentially engage the eye, and a tissue migration bolster structure configured to be positioned circumferentially between the inner and outer circumferential seals and to prevent migration of tissue of the eye toward the eye surface engagement assembly when a vacuum load is applied within the assembly to cause vacuum engagement of the inner and outer seals against the eye.

摘要翻译： 一个实施例涉及用于患者眼睛上的眼科干预的患者接口系统，包括：壳体; 耦合到壳体并具有焦轴的光学透镜; 眼表面接合组件，其联接到所述壳体并且包括内密封件，所述内密封件具有内密封件直径并且构造成周向接合所述眼睛;外密封件，其具有外密封件直径并且构造成周向接合所述眼部;以及组织移植垫 结构构造成周向地定位在内外周密封之间并且当在组件内施加真空负载以防止内密封件和外密封件与眼睛的真空接合时，防止眼睛组织向眼表面接合组件移动 。

公开(公告)号：US07599591B2

公开(公告)日：2009-10-06

申请号：US11653663

申请日：2007-01-12

申请人： Dan E. Andersen ,  David G. Angeley ,  Philip Gooding ,  Michael W. Wiltberger ,  David H. Mordaunt

发明人： Dan E. Andersen ,  David G. Angeley ,  Philip Gooding ,  Michael W. Wiltberger ,  David H. Mordaunt

IPC分类号： G02B6/06

CPC分类号： A61B3/0008 ,  A61B3/135 ,  A61F9/008 ,  A61F9/00821 ,  A61F9/00823 ,  A61F9/009 ,  A61F2009/00863 ,  A61F2009/00872 ,  A61F2009/00897 ,  G02B6/32 ,  G02B6/3512 ,  G02B6/3548 ,  G02B6/357 ,  G02B6/3582 ,  G02B26/105

摘要： An optical device and method for varying an optical characteristic of an optical beam can include a plurality of optical fibers each having an input end, an output end, and a core, wherein each of the optical fibers has an effective area and a numerical aperture, and a beam-deviating component for moving at least one of the optical fiber input ends and the optical beam relative to each other such that the optical beam selectively enters the input ends one at a time and is transmitted out the output ends one at a time, wherein at least one of the effective areas and the numerical apertures varies among the plurality of optical fibers such that the optical beam transmitted out of the output ends has a varying optical characteristic.

摘要翻译： 用于改变光束的光学特性的光学装置和方法可以包括多个光纤，每个光纤具有输入端，输出端和芯，其中每个光纤具有有效面积和数值孔径， 以及光束偏离部件，用于相对于彼此移动光纤输入端和光束中的至少一个，使得光束一次一个地选择性地进入输入端，并且一次一个地输出输出端 其中，所述有效面积和所述数值孔径中的至少一个在所述多根光纤中变化，使得从所述输出端传出的光束具有变化的光学特性。

公开(公告)号：US20130102895A1

公开(公告)日：2013-04-25

申请号：US13279181

申请日：2011-10-21

申请人： Philip Gooding ,  Michael Wiltberger

发明人： Philip Gooding ,  Michael Wiltberger

IPC分类号： A61B6/00

CPC分类号： A61F9/00827 ,  A61B3/10 ,  A61F9/009 ,  A61F2009/00844 ,  A61F2009/00853 ,  A61F2009/00865 ,  A61F2009/0087 ,  A61F2009/00872 ,  A61F2009/00887

摘要： One or more geometric markers may be created on an eye preoperatively. Two or more fiducials coupled to or formed within a patient interface may be lined up with the geometric markers. An imaging device coupled to the patient interface and having a field of view oriented through the patient interface and toward the eye of the patient may be utilized to capture one or more images that contain not only image aspects pertinent to the positions of anatomical portions of the eye, but also image aspects pertinent to the locations of fiducials coupled to or formed within portions of the patient interface. The images may be analyzed to determine a geometric relationship between the anatomy of the eye and the associated system hardware.

摘要翻译： 术前可以在眼睛上创建一个或多个几何标记。 耦合到或形成在患者界面内的两个或更多个基准可以与几何标记排成一列。 耦合到患者界面并且具有定向穿过患者界面并朝向患者眼睛的视野的成像装置可用于捕获一个或多个图像，其不仅包含与所述患者的解剖部分的位置有关的图像方面 眼睛，还包括与患者界面的部分内耦合或形成的基准点的位置相关的图像方面。 可以分析图像以确定眼睛的解剖结构与相关联的系统硬件之间的几何关系。

公开(公告)号：US20100137850A1

公开(公告)日：2010-06-03

申请号：US12702242

申请日：2010-02-08

申请人： William Culbertson ,  Barry Seibel ,  Neil Friedman ,  Georg Schule ,  Philip Gooding

发明人： William Culbertson ,  Barry Seibel ,  Neil Friedman ,  Georg Schule ,  Philip Gooding

IPC分类号： A61F9/008

CPC分类号： A61F9/00754 ,  A61F2/16 ,  A61F2/1613 ,  A61F2/1637 ,  A61F2/1648 ,  A61F2/1662 ,  A61F9/00 ,  A61F9/008 ,  A61F9/00825 ,  A61F9/009 ,  A61F2002/1683 ,  A61F2009/00859 ,  A61F2009/0087 ,  A61F2009/00872 ,  A61F2009/0088 ,  A61F2009/00887 ,  A61F2009/00897 ,  A61F2220/0016

摘要： A method of treating a lens of a patient's eye includes generating a light beam, deflecting the light beam using a scanner to form a treatment pattern of the light beam, delivering the treatment pattern to the lens of a patient's eye to create a plurality of cuts in the lens in the form of the treatment pattern to break the lens up into a plurality of pieces, and removing the lens pieces from the patient's eye. The lens pieces can then be mechanically removed. The light beam can be used to create larger segmenting cuts into the lens, as well as smaller softening cuts that soften the lens for easier removal.

摘要翻译： 治疗患者眼睛的透镜的方法包括产生光束，使用扫描器偏转光束以形成光束的治疗图案，将治疗图案传送到患者眼睛的透镜，以产生多个切口 以处理图案的形式在透镜中将透镜打破成多个片，并且从患者的眼睛移除透镜片。 然后可以机械地移除透镜片。 光束可用于在镜头中产生更大的分割切口，以及较小的软化切口，从而软化透镜以便于移除。

公开(公告)号：US20090012507A1

公开(公告)日：2009-01-08

申请号：US12048185

申请日：2008-03-13

申请人： William Culbertson ,  Barry Seibel ,  Neil Friedman ,  Georg Schule ,  Philip Gooding

发明人： William Culbertson ,  Barry Seibel ,  Neil Friedman ,  Georg Schule ,  Philip Gooding

IPC分类号： A61F9/008

CPC分类号： A61F2/1613 ,  A61F2/16 ,  A61F2/1637 ,  A61F2/1648 ,  A61F2/1662 ,  A61F9/00 ,  A61F9/00754 ,  A61F9/008 ,  A61F9/00812 ,  A61F9/00825 ,  A61F9/009 ,  A61F2002/1683 ,  A61F2002/16901 ,  A61F2009/00859 ,  A61F2009/0087 ,  A61F2009/00872 ,  A61F2009/0088 ,  A61F2009/00887 ,  A61F2009/00897 ,  A61F2220/0016

摘要： A method of treating a lens of a patient's eye includes generating a light beam, deflecting the light beam using a scanner to form a treatment pattern of the light beam, delivering the treatment pattern to the lens of a patient's eye to create a plurality of cuts in the lens in the form of the treatment pattern to break the lens up into a plurality of pieces, and removing the lens pieces from the patient's eye. The lens pieces can then be mechanically removed. The light beam can be used to create larger segmenting cuts into the lens, as well as smaller softening cuts that soften the lens for easier removal.

摘要翻译： 治疗患者眼睛的透镜的方法包括产生光束，使用扫描器偏转光束以形成光束的治疗图案，将治疗图案传送到患者眼睛的透镜，以产生多个切口 以处理图案的形式在透镜中将透镜打破成多个片，并且从患者的眼睛移除透镜片。 然后可以机械地移除透镜片。 光束可用于在镜头中产生更大的分割切口，以及较小的软化切口，从而软化透镜以便于移除。

公开(公告)号：US20130103009A1

公开(公告)日：2013-04-25

申请号：US13279152

申请日：2011-10-21

申请人： Philip Gooding

发明人： Philip Gooding

IPC分类号： A61F9/009

CPC分类号： A61F9/009 ,  A61B18/20 ,  A61F9/00812 ,  A61F9/00827 ,  A61F2009/0052 ,  A61F2009/00844 ,  A61F2009/00853 ,  A61F2009/00865 ,  A61F2009/0087 ,  A61F2009/00872 ,  A61F2009/00887 ,  A61F2009/00889

摘要： One embodiment is directed to a method for interfacing an ophthalmic intervention system with an eye of a patient, comprising: placing a patient interface assembly comprising a housing, an optical lens coupled to the housing, and an eye engagement assembly coupled to the housing, the eye engagement assembly comprising an inner seal and an outer seal, into contact with the eye of the patient by sealably engaging the eye with the inner and outer seals in a vacuum zone defined between the inner and outer seals; applying a vacuum load between the inner and outer seals to engage the eye using the vacuum load; and physically limiting an amount of distension of the eye in the vacuum zone.

摘要翻译： 一个实施例涉及一种用于将眼科干预系统与患者的眼睛接合的方法，包括：放置患者接口组件，其包括壳体，联接到所述壳体的光学透镜以及耦合到所述壳体的眼睛接合组件， 眼睛接合组件包括内部密封件和外部密封件，其通过在限定在内部和外部密封件之间的真空区域中将眼睛与内部密封件和外部密封件密封地接合而与患者的眼睛接触; 在内密封件和外密封件之间施加真空负载以使用真空负载接合眼睛; 并在物理上限制眼睛在真空区中的膨胀量。

公开(公告)号：US20110202046A1

公开(公告)日：2011-08-18

申请号：US13011807

申请日：2011-01-21

申请人： David G Angeley ,  Philip Gooding ,  Bruce R. Woodley ,  George Marcellino

发明人： David G Angeley ,  Philip Gooding ,  Bruce R. Woodley ,  George Marcellino

IPC分类号： A61F9/008

CPC分类号： A61F9/00825 ,  A61B3/102 ,  A61B3/107 ,  A61B5/0066 ,  A61F9/008 ,  A61F9/0084 ,  A61F9/009 ,  A61F2009/00851 ,  A61F2009/00865 ,  A61F2009/0087 ,  A61F2009/00872 ,  A61F2009/00876 ,  A61F2009/00889 ,  A61F2009/00897 ,  G06T7/0012 ,  G06T7/13 ,  G06T7/149 ,  G06T2207/10101 ,  G06T2207/30041

摘要： Systems and methods are described for cataract intervention. In one embodiment a system comprises a laser source configured to produce a treatment beam comprising a plurality of laser pulses; an integrated optical system comprising an imaging assembly operatively coupled to a treatment laser delivery assembly such that they share at least one common optical element, the integrated optical system being configured to acquire image information pertinent to one or more targeted tissue structures and direct the treatment beam in a 3-dimensional pattern to cause breakdown in at least one of the targeted tissue structures; and a controller operatively coupled to the laser source and integrated optical system, and configured to adjust the laser beam and treatment pattern based upon the image information, and distinguish two or more anatomical structures of the eye based at least in part upon a robust least squares fit analysis of the image information.

摘要翻译： 描述白内障干预的系统和方法。 在一个实施例中，系统包括被配置为产生包括多个激光脉冲的治疗束的激光源; 一种集成光学系统，包括可操作地耦合到治疗激光输送组件的成像组件，使得它们共享至少一个公共光学元件，所述集成光学系统被配置为获取与一个或多个目标组织结构相关的图像信息，并且指导治疗束 在3维图案中以引起至少一个目标组织结构中的破坏; 以及控制器，其可操作地耦合到所述激光源和集成光学系统，并且被配置为基于所述图像信息来调整所述激光束和治疗图案，并且至少部分地基于鲁棒的最小二乘法来区分所述眼睛的两个或多个解剖结构 适合分析图像信息。