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1.发明申请Recombinant lentiviral vector for expression of a flaviviridae protein and applications thereof as a vaccine 审中-公开用于表达黄病毒科蛋白的重组慢病毒载体及其作为疫苗的应用公开(公告)号：US20090214589A1
公开(公告)日：2009-08-27
申请号：US11596675
申请日：2005-05-16
IPC分类号： A61K39/12 , C12N15/867 , C12N5/00 , C12P21/06 , C12Q1/70
CPC分类号： C12N15/86 , A61K2039/53 , C07K14/005 , C12N2740/16043 , C12N2770/24134 , Y02A50/386 , Y02A50/388 , Y02A50/394
摘要： Use of a recombinant lentiviral vector comprising a polynucleotide fragment encoding at least one protein of a virus of the family Flaviviridae or an immunogenic peptide of at least 8 amino acids of said protein, for preparing a pharmaceutical composition intended for the prevention and/or the treatment of a Flaviviridae infection in a sensitive species.
摘要翻译： 使用重组慢病毒载体，其包含编码至少一种黄病毒科病毒蛋白的多核苷酸片段或所述蛋白质的至少8个氨基酸的免疫原性肽，用于制备用于预防和/或治疗的药物组合物 的敏感物种中的黄病毒科感染。
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2.发明授权Recombinant lentiviral vector for expression of a flaviviridae protein and applications thereof as a vaccine 有权用于表达黄病毒科蛋白的重组慢病毒载体及其作为疫苗的应用公开(公告)号：US08716013B2
公开(公告)日：2014-05-06
申请号：US12929215
申请日：2011-01-07
CPC分类号： C12N15/86 , A61K2039/53 , C07K14/005 , C12N2740/16043 , C12N2770/24134 , Y02A50/386 , Y02A50/388 , Y02A50/394
摘要： Use of a recombinant lentiviral vector comprising a polynucleotide fragment encoding at least one protein of a virus of the family Flaviviridae or an immunogenic peptide of at least 8 amino acids of said protein, for preparing a pharmaceutical composition intended for the prevention and/or the treatment of a Flaviviridae infection in a sensitive species.
摘要翻译： 使用重组慢病毒载体，其包含编码至少一种黄病毒科病毒蛋白的多核苷酸片段或所述蛋白质的至少8个氨基酸的免疫原性肽，用于制备用于预防和/或治疗的药物组合物 的敏感物种中的黄病毒科感染。
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3.发明申请Recombinant lentiviral vector for expression of a flaviviridae protein and applications thereof as a vaccine 有权用于表达黄病毒科蛋白的重组慢病毒载体及其作为疫苗的应用公开(公告)号：US20110206710A1
公开(公告)日：2011-08-25
申请号：US12929215
申请日：2011-01-07
CPC分类号： C12N15/86 , A61K2039/53 , C07K14/005 , C12N2740/16043 , C12N2770/24134 , Y02A50/386 , Y02A50/388 , Y02A50/394
摘要： Use of a recombinant lentiviral vector comprising a polynucleotide fragment encoding at least one protein of a virus of the family Flaviviridae or an immunogenic peptide of at least 8 amino acids of said protein, for preparing a pharmaceutical composition intended for the prevention and/or the treatment of a Flaviviridae infection in a sensitive species.
摘要翻译： 使用重组慢病毒载体，其包含编码至少一种黄病毒科病毒蛋白的多核苷酸片段或所述蛋白质的至少8个氨基酸的免疫原性肽，用于制备用于预防和/或治疗的药物组合物 的敏感物种中的黄病毒科感染。
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公开(公告)号：US20070128224A1
公开(公告)日：2007-06-07
申请号：US10581356
申请日：2004-12-02
申请人： Sylvie Van Der Werf , Nicolas Escriou , Bernadette Crescenzo-Chaigne , Jean-Claude Manuguerra , Frederick Kunst , Benoit Callendret , Jean-Michel Betton , Valerie Lorin , Sylvie Gerbaud , Ana Burguiere , Saliha Azebi , Pierre Charneau , Frederic Tangy , Chantal Combredet , Jean-Francois Delagneau , Monique Martin
发明人： Sylvie Van Der Werf , Nicolas Escriou , Bernadette Crescenzo-Chaigne , Jean-Claude Manuguerra , Frederick Kunst , Benoit Callendret , Jean-Michel Betton , Valerie Lorin , Sylvie Gerbaud , Ana Burguiere , Saliha Azebi , Pierre Charneau , Frederic Tangy , Chantal Combredet , Jean-Francois Delagneau , Monique Martin
IPC分类号： A61K39/215 , C12Q1/70 , C07H21/04 , C07K14/165 , C07K16/10 , C12N5/06
CPC分类号： C07K14/005 , C12N7/00 , C12N2770/20022 , G01N33/569
摘要： The invention relates to a novel strain of severe acute respiratory syndrome (SARS)-associated coronavirus, resulting from a sample collected in Hanoi (Vietnam), reference number 031589, nucleic acid molecules originating from the genome of same, proteins and peptides coded by said nucleic acid molecules and, more specifically, protein N and the applications thereof, for example, as diagnostic reagents and/or as a vaccine.
摘要翻译： 本发明涉及由河内（越南）收集的样品，参考号031589，源自其基因组的核酸分子产生的重症急性呼吸综合征（SARS）相关冠状病毒的新型菌株，由所述 核酸分子，更具体地，蛋白N及其应用，例如作为诊断试剂和/或疫苗。
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公开(公告)号：US08222029B2
公开(公告)日：2012-07-17
申请号：US12083532
申请日：2006-10-17
申请人： Pierre Charneau , Philippe Despres
发明人： Pierre Charneau , Philippe Despres
CPC分类号： A61K39/12 , A61K2039/5256 , C07K14/005 , C12N2740/15043 , C12N2770/24122 , C12N2770/24134 , C12N2770/24171 , Y02A50/394
摘要： Methods of eliciting humoral responses, methods of immunization, and methods of vaccination using lentiviral vector are disclosed. Additionally, immunogenic compositions and vaccines for West Nile Virus are disclosed.
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公开(公告)号：US08158413B2
公开(公告)日：2012-04-17
申请号：US11250616
申请日：2005-10-17
申请人： Pierre Charneau , Philippe Despres
发明人： Pierre Charneau , Philippe Despres
CPC分类号： C07K14/005 , A61K39/12 , A61K2039/5256 , C12N2740/15043 , C12N2770/24122 , C12N2770/24134 , C12N2770/24171 , Y02A50/394
摘要： Methods of eliciting humoral responses, methods of immunization, and methods of vaccination using lentiviral vector are disclosed. Additionally, immunogenic compositions and vaccines for West Nile Virus are disclosed.
摘要翻译： 公开了引起体液应答的方法，免疫方法和使用慢病毒载体的疫苗接种方法。 另外，公开了用于西尼罗河病毒的免疫原性组合物和疫苗。
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公开(公告)号：US20110086065A9
公开(公告)日：2011-04-14
申请号：US12083532
申请日：2006-10-17
申请人： Pierre Charneau , Philippe Despres
发明人： Pierre Charneau , Philippe Despres
CPC分类号： A61K39/12 , A61K2039/5256 , C07K14/005 , C12N2740/15043 , C12N2770/24122 , C12N2770/24134 , C12N2770/24171 , Y02A50/394
摘要： Methods of eliciting humoral responses, methods of immunization, and methods of vaccination using lentiviral vector are disclosed. Additionally, immunogenic compositions and vaccines for West Nile Virus are disclosed.
摘要翻译： 公开了引起体液应答的方法，免疫方法和使用慢病毒载体的疫苗接种方法。 另外，公开了用于西尼罗河病毒的免疫原性组合物和疫苗。
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8.发明申请Novel Isolated And Purified Strains Of Chikungunya Virus And Polynucleotides And Polypetide Sequences, Diagnostic And Immunogenical Uses Thereof 审中-公开基孔肯雅病毒和多核苷酸和多核苷酸序列的新型分离和纯化的菌株，其诊断和免疫应用公开(公告)号：US20100055105A1
公开(公告)日：2010-03-04
申请号：US12225111
申请日：2007-03-15
IPC分类号： A61K39/395 , C12N7/00 , C07H21/04 , C12N15/63 , C07K14/005 , C07K16/08 , C12Q1/70 , A61K35/76 , A61K31/7088 , A61K38/16
CPC分类号： G01N33/56983 , A61K38/00 , A61K39/00 , C07K14/005 , C07K16/1081 , C12N7/00 , C12N2770/36121 , C12N2770/36122 , C12N2770/36131 , G01N2333/181 , G01N2800/32 , Y02A50/383 , Y02A50/51
摘要： The present invention concerns wild-strains of Chikungunya virus isolated from patients exhibiting severe forms of infection and stemming from a human arbovirosis epidemy. The present invention also concerns polypeptide sequences and fragment thereof derived from their genome, the polynucleotide encoding same and their use as diagnostic products, as vaccine and/or as immunogenic compositions.
摘要翻译： 本发明涉及从表现出严重感染形式的患者和从人类阿博病病毒流行中产生的患者分离的基孔肯雅病毒的野生菌株。 本发明还涉及衍生自其基因组的多肽序列及其片段，编码它们的多核苷酸及其作为诊断产品的用途，作为疫苗和/或免疫原性组合物。
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公开(公告)号：US20100028382A1
公开(公告)日：2010-02-04
申请号：US12083532
申请日：2006-10-17
申请人： Pierre Charneau , Philippe Despres
发明人： Pierre Charneau , Philippe Despres
CPC分类号： A61K39/12 , A61K2039/5256 , C07K14/005 , C12N2740/15043 , C12N2770/24122 , C12N2770/24134 , C12N2770/24171 , Y02A50/394
摘要： Methods of eliciting humoral responses, methods of immunization, and methods of vaccination using lentiviral vector are disclosed. Additionally, immunogenic compositions and vaccines for West Nile Virus are disclosed.
摘要翻译： 公开了引起体液应答的方法，免疫方法和使用慢病毒载体的疫苗接种方法。 另外，公开了用于西尼罗河病毒的免疫原性组合物和疫苗。
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公开(公告)号：US20070087354A1
公开(公告)日：2007-04-19
申请号：US11250616
申请日：2005-10-17
申请人： Pierre Charneau , Philippe Despres
发明人： Pierre Charneau , Philippe Despres
CPC分类号： C07K14/005 , A61K39/12 , A61K2039/5256 , C12N2740/15043 , C12N2770/24122 , C12N2770/24134 , C12N2770/24171 , Y02A50/394
摘要： Methods of eliciting humoral responses, methods of immunization, and methods of vaccination using lentiviral vector are disclosed. Additionally, immunogenic compositions and vaccines for West Nile Virus are disclosed.
摘要翻译： 公开了引起体液应答的方法，免疫方法和使用慢病毒载体的疫苗接种方法。 另外，公开了用于西尼罗河病毒的免疫原性组合物和疫苗。
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