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1.发明授权公开(公告)号：US06399294B1
公开(公告)日：2002-06-04
申请号：US08817441
申请日：1997-07-11
申请人： Pierre Charneau , François Clavel , Andrew Borman , Caroline Quillent , Denise Guetard , Luc Montagnier , Jacqueline Donjon De Saint-Martin , Jacques Cohen
发明人： Pierre Charneau , François Clavel , Andrew Borman , Caroline Quillent , Denise Guetard , Luc Montagnier , Jacqueline Donjon De Saint-Martin , Jacques Cohen
IPC分类号： C12Q170
CPC分类号： C07K14/005 , C12N2740/16021 , C12N2740/16022 , C12N2740/16043 , C12N2740/16122 , C12N2740/16222 , C12N2740/16322 , G01N33/56988 , Y10S435/975
摘要： An HIV-1 type (or subtype) O retrovirus protein, or a natural or synthetic polypeptide or peptide including at least a part of said protein, which is capable of being recognised by antibodies isolated from a serum resulting from infection by an HIV-1 type O VAU strain or an HIV-1 type (or subtype) O DUR strain.
摘要翻译： HIV-1型（或亚型）O逆转录病毒蛋白，或包含至少一部分所述蛋白质的天然或合成多肽或肽，其能够被从HIV-1感染引起的血清分离的抗体识别 O型VAU菌株或HIV-1型（或亚型）O DUR菌株。
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2.发明授权Nucleotide sequences of HIV-1 group (or subgroup) O retroviral antigens 失效HIV-1组（或亚组）O逆转录病毒抗原的核苷酸序列公开(公告)号：US08236324B2
公开(公告)日：2012-08-07
申请号：US11591678
申请日：2006-11-02
申请人： Pierre Charneau , François Clavel , Andrew Borman , Caroline Quillent , Denise Guetard , Luc Montagnier , Jacqueline Donjon de Saint-Martin , Jacques Cohen
发明人： Pierre Charneau , François Clavel , Andrew Borman , Caroline Quillent , Denise Guetard , Luc Montagnier , Jacqueline Donjon de Saint-Martin , Jacques Cohen
IPC分类号： A61K39/21
CPC分类号： C07K14/005 , C12N2740/16021 , C12N2740/16022 , C12N2740/16043 , C12N2740/16122 , C12N2740/16222 , C12N2740/16322 , G01N33/56988 , Y10S435/975
摘要： An HIV-1 type (or subtype) O retrovirus protein, or a natural or synthetic polypeptide or peptide including at least a part of said protein, which is capable of being recognized by antibodies isolated from a serum resulting from infection by an HIV-1 type O VAU strain or an HIV-1 type (or subtype) O DUR strain.
摘要翻译： HIV-1型（或亚型）O逆转录病毒蛋白，或包含至少一部分所述蛋白质的天然或合成多肽或肽，其能够被从HIV-1感染引起的血清分离的抗体识别 O型VAU菌株或HIV-1型（或亚型）O DUR菌株。
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3.发明授权公开(公告)号：US07157225B2
公开(公告)日：2007-01-02
申请号：US10026741
申请日：2001-12-27
申请人： Pierre Charneau , François Clavel , Andrew Borman , Caroline Quillent , Denise Guetard , Luc Montagnier , Jacqueline Donjon De Saint-Martin , Jacques H. M. Cohen
发明人： Pierre Charneau , François Clavel , Andrew Borman , Caroline Quillent , Denise Guetard , Luc Montagnier , Jacqueline Donjon De Saint-Martin , Jacques H. M. Cohen
CPC分类号： C07K14/005 , C12N2740/16021 , C12N2740/16022 , C12N2740/16043 , C12N2740/16122 , C12N2740/16222 , C12N2740/16322 , G01N33/56988 , Y10S435/975
摘要： An HIV-1 type (or subtype) O retrovirus protein, or a natural or synthetic polypeptide or peptide including at least a part of said protein, which is capable of being recognised by antibodies isolated from a serum resulting from infection by an HIV-1 type O VAU strain or an HIV-1 type (or subtype) O DUR strain.
摘要翻译： HIV-1型（或亚型）O逆转录病毒蛋白，或包含至少一部分所述蛋白质的天然或合成多肽或肽，其能够被从HIV-1感染引起的血清分离的抗体识别 O型VAU菌株或HIV-1型（或亚型）O DUR菌株。
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4.发明申请Nucleotide sequences of HIV-1 group (or subgroup) O retroviral antigens 失效HIV-1组（或亚组）O逆转录病毒抗原的核苷酸序列公开(公告)号：US20080261197A1
公开(公告)日：2008-10-23
申请号：US11591678
申请日：2006-11-02
申请人： Pierre Charneau , Francois Clavel , Andrew Borman , Caroline Quillent , Denise Guetard , Luc Montagnier , Jacqueline Donjon De Saint-Martin , Jacques H.M. Cohen
发明人： Pierre Charneau , Francois Clavel , Andrew Borman , Caroline Quillent , Denise Guetard , Luc Montagnier , Jacqueline Donjon De Saint-Martin , Jacques H.M. Cohen
IPC分类号： C12Q1/70 , C07K14/16 , C07K5/06 , C07K5/08 , C07K5/10 , C07K16/10 , C12N1/00 , C12N1/20 , C12N7/00 , C12N15/63 , C07K7/06 , C07K7/08 , C07K14/00 , C07H21/00
CPC分类号： C07K14/005 , C12N2740/16021 , C12N2740/16022 , C12N2740/16043 , C12N2740/16122 , C12N2740/16222 , C12N2740/16322 , G01N33/56988 , Y10S435/975
摘要： An HIV-1 type (or subtype) O retrovirus protein, or a natural or synthetic polypeptide or peptide including at least a part of said protein, which is capable of being recognised by antibodies isolated from a serum resulting from infection by an HIV-1 type O VAU strain or an HIV-1 type (or subtype) O DUR strain.
摘要翻译： HIV-1型（或亚型）O逆转录病毒蛋白，或包含至少一部分所述蛋白质的天然或合成多肽或肽，其能够被从HIV-1感染引起的血清分离的抗体识别 O型VAU菌株或HIV-1型（或亚型）O DUR菌株。
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5.发明授权Human immunodeficiency virus co-receptor variants associated with resistance to virus infection 失效与抗病毒感染相关的人类免疫缺陷病毒共受体变体
公开(公告)号：US6153431A
公开(公告)日：2000-11-28
申请号：US87232
申请日：1998-05-28
IPC分类号： C07K14/715 , C12N15/12 , C12N5/10 , C07H21/04
CPC分类号： C07K14/7158 , C07K2319/00
摘要： The present invention relates to variants of the CCR5 human immunodeficiency virus ("HIV") co-receptor which result in a resistance of CCR5 expressing cells to HIV infection. The detection of such mutations may be used to identify individuals at lower risk for infection relative to the general population who, if infected, may exhibit slower progression to AIDS. Further, the present invention provides for methods of inhibiting HIV infection of a cell expressing the CCR5 receptor, comprising introducing, into the cell, a nucleic acid encoding a CCR5 variant.
摘要翻译： 本发明涉及CCR5人免疫缺陷病毒（“HIV”）共同受体的变体，其导致CCR5表达细胞对HIV感染的抗性。 这种突变的检测可用于鉴定相对于一般群体感染风险较低的个体，如果被感染，可能表现出较慢的AIDS进展。 此外，本发明提供了抑制表达CCR5受体的细胞的HIV感染的方法，包括向细胞中引入编码CCR5变体的核酸。
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