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    System and method for the detection and treatment of infection by a microbial agent associated with HIV infection
    3.
    发明授权
    System and method for the detection and treatment of infection by a microbial agent associated with HIV infection 有权
    用于检测和治疗与HIV感染相关的微生物剂感染的系统和方法

    公开(公告)号：US09580758B2

    公开(公告)日：2017-02-28

    申请号：US14537111

    申请日：2014-11-10

    申请人： Luc Montagnier

    发明人： Luc Montagnier

    IPC分类号： C12Q1/68 ,  A61K31/65 ,  A61K31/496 ,  A61K31/00 ,  C07H21/02

    CPC分类号： A61K31/65 ,  A61K9/0053 ,  A61K31/00 ,  A61K31/198 ,  A61K31/496 ,  A61K31/711 ,  A61K35/00 ,  A61K36/00 ,  A61K38/19 ,  C12Q1/689 ,  C12Q2600/158

    摘要： A method of treating a patient, comprising administering at least one antibiotic, e.g., doxycycline and ciprofloxacin, sufficient to substantially treat an intracellular bacterial organism present in at least erythrocytes, e.g., over a course of at least two weeks; and subsequently administering at least one immunostimulant, e.g., which directly or indirectly increases levels of immunostimulatory cytokines in the patient, and at least one antioxidant, e.g., glutathione, to effectively treat a coinfection of the patient with a virus. The intracellular bacterial organism may be a rickettsiales-like organism, and the virus may be HIV.

    摘要翻译： 一种治疗患者的方法，包括施用至少一种抗生素，例如多西环素和环丙沙星，其足以基本上治疗存在于至少红细胞中的细胞内细菌生物，例如在至少两周的过程中; 并且随后施用至少一种免疫刺激剂，例如其直接或间接增加患者体内的免疫刺激性细胞因子的水平，以及至少一种抗氧化剂，例如谷胱甘肽，以有效地治疗患有病毒的患者的共感染。 细胞内细菌生物体可能是立克次体样生物，病毒可能是HIV。

    METHOD FOR DIGITAL TRANSDUCTION OF DNA IN LIVING CELLS
    4.
    发明申请
    METHOD FOR DIGITAL TRANSDUCTION OF DNA IN LIVING CELLS 审中-公开
    数字转录生物细胞中DNA的方法

    公开(公告)号：US20160002620A1

    公开(公告)日：2016-01-07

    申请号：US14792039

    申请日：2015-07-06

    申请人： Luc Montagnier

    发明人： Luc Montagnier

    IPC分类号： C12N13/00

    CPC分类号： C12Q1/689 ,  C12Q1/6886 ,  G01N37/005

    摘要： A system and method for inducing cytotoxicity, comprising a receiver configured to receive an electromagnetic signal from a container, using a receiver configured to capture electromagnetic emissions from the container over a frequency range of at least 100 Hz to 10,000 Hz; an amplifier configured to amplify the received electromagnetic signal; and an emitter configured to emit the amplified electromagnetic signal in proximity to living cells. DNA from a pathogen is amplified using PCR, purified, and serially diluted. Electromagnetic signals from the diluted DNA are received, and optionally stored. The receive signal is amplified and emitted in proximity to living cells, to produce under selected circumstances, a cytopathic effect.

    摘要翻译： 一种用于诱导细胞毒性的系统和方法，包括接收器，其被配置为从容器接收电磁信号，所述接收器被配置为在至少100Hz至10,000Hz的频率范围上捕获来自所述容器的电磁发射; 放大器，被配置为放大所接收的电磁信号; 以及发射器，被配置为发射靠近活细胞的放大的电磁信号。 使用PCR扩增来自病原体的DNA，纯化并连续稀释。 接收来自稀释的DNA的电磁信号，并任选地储存。 接收信号被放大并发射在活细胞附近，在选定的情况下产生细胞病变效应。

    Detection of DNA sequences as risk factors for HIV infection
    5.
    发明授权
    Detection of DNA sequences as risk factors for HIV infection 有权
    检测DNA序列作为HIV感染的危险因素

    公开(公告)号：US09133525B2

    公开(公告)日：2015-09-15

    申请号：US13752003

    申请日：2013-01-28

    申请人： Luc Montagnier

    发明人： Luc Montagnier

    IPC分类号： C12P19/34 ,  C12Q1/68 ,  C12N1/20 ,  A61K31/7052 ,  A61K31/65 ,  C12Q1/70 ,  C12N15/11

    CPC分类号： C12Q1/703 ,  A61K31/65 ,  A61K31/7052 ,  C12N1/20 ,  C12N15/11 ,  C12Q1/689 ,  Y02A50/402

    摘要： A method for identifying a risk factor for diseases, disorders or conditions, such as those caused by human immunodeficiency virus, using the polymerase chain reaction and specific primers. Methods for treating patients having these diseases, disorders or conditions by antimicrobial treatment of the risk factor by combined antiviral and antibacterial treatment or by sustaining or stimulating the subject's immune system. Methods for screening biological products including red blood cell preparations. Primers and methods for detecting nucleic acids or microbial agents associated with red blood cells, such as those associated with red blood cells in subjects infected with HIV and undergoing antiretroviral therapy.

    摘要翻译： 使用聚合酶链式反应和特异性引物鉴定疾病，病症或病症（例如由人免疫缺陷病毒引起的危险因素）的方法。 通过联合抗病毒和抗菌治疗或通过维持或刺激受试者的免疫系统来对患有这些疾病，病症或病症的患者进行抗微生物治疗危险因素的方法。 筛选生物制品，包括红细胞制剂的方法。 用于检测与红细胞相关的核酸或微生物剂的引物和方法，例如与感染HIV并进行抗逆转录病毒治疗的受试者中与红细胞相关的那些。

    Nucleotide sequences derived from the genome of retroviruses of the HIV-1, HIV-2 and SIV type, and their uses in particular for the amplification of the genomes of these retroviruses and for the in vitro diagnosis of the diseases due to these viruses
    9.
    发明授权
    Nucleotide sequences derived from the genome of retroviruses of the HIV-1, HIV-2 and SIV type, and their uses in particular for the amplification of the genomes of these retroviruses and for the in vitro diagnosis of the diseases due to these viruses 有权
    衍生自HIV-1，HIV-2和SIV类型的逆转录病毒基因组的核苷酸序列及其用于特异性扩增这些逆转录病毒基因组的用途以及由于这些病毒引起的疾病的体外诊断

    公开(公告)号：US07022814B1

    公开(公告)日：2006-04-04

    申请号：US09670105

    申请日：2000-09-26

    申请人： Maurice Moncany ,  Luc Montagnier

    发明人： Maurice Moncany ,  Luc Montagnier

    IPC分类号： C07K1/00

    CPC分类号： C07K14/005 ,  C12N2740/15022 ,  C12N2740/16022

    摘要： The present invention relates to polypeptides encoded by a nucleotide sequence from an HIV-1, HIV-2, or SIV viral genome, in which the nucleotide sequence is amplified from the viral genome using a pair of primers that contain sequences that are conserved between different HIV and SIV strains. The primers are insensitive to variations in the genomes of different HIV and SIV isolates and, therefore, can be used to amplify nucleotide sequences from HIV-1, HIV-2, and SIV strains. The invention also relates to antibodies directed against these polypeptides and methods and kits for diagnosing viral infection.

    摘要翻译： 本发明涉及由HIV-1，HIV-2或SIV病毒基因组的核苷酸序列编码的多肽，其中使用包含不同序列之间保守的序列的一对引物从病毒基因组扩增核苷酸序列 HIV和SIV菌株。 引物对不同HIV和SIV分离株的基因组变化不敏感，因此可用于扩增HIV-1，HIV-2和SIV毒株的核苷酸序列。 本发明还涉及针对这些多肽的抗体以及用于诊断病毒感染的方法和试剂盒。