-
1.发明申请3-Alpha-hydroxy 21-n-heteroaryl-pregnane derivatives for modulation of brain excitability and a process for the production thereof 审中-公开用于调节脑兴奋性的3-α-羟基21-n-杂芳基 - 孕烷衍生物及其制备方法公开(公告)号：US20090118248A1
公开(公告)日：2009-05-07
申请号：US11587138
申请日：2005-04-22
申请人： Ping W. Chang , Ning Zhong , Xinping Fang , Shao-Kun Pang , Chi-Nung Hsiao , Tsung-Cheng Hu
发明人： Ping W. Chang , Ning Zhong , Xinping Fang , Shao-Kun Pang , Chi-Nung Hsiao , Tsung-Cheng Hu
CPC分类号： C07J43/003 , C07J7/002 , C07J7/0085
摘要： The invention relates to a novel multi step process of making compounds of Formula I: wherein R1 is an alkoxy group and R2 is an optionally substituted, N-attached heteroaryl. The hydrogen at the 5-position can be α or β isomer, preferably α. Preferably the compound of Formula I is 17β isomer. The invention also relates to novel 3α-hydroxy-3β-substituted-17-substituted steroid compounds having GABAA receptor modulating activity, pharmaceutical compositions comprising these compounds, and the use of these compounds in a method of modulating brain excitability.
摘要翻译： 本发明涉及制备式I化合物的新型多步骤方法：其中R 1是烷氧基，R 2是任选取代的，N-连接的杂芳基。 5位氢可以是α或β异构体，最好是α。 优选地，式I的化合物是17β型异构体。 本发明还涉及具有GABA A受体调节活性的新的3α-羟基-3β-取代的-17-取代的类固醇化合物，包含这些化合物的药物组合物，以及这些化合物在调节脑兴奋性的方法中的用途。
-
公开(公告)号：US4772641A
公开(公告)日：1988-09-20
申请号：US746821
申请日：1985-06-20
IPC分类号： C08L61/32 , C07D251/70 , C08G12/40 , C08G12/46 , C08L61/00 , C08L61/20 , C09K8/04 , C09K8/508 , C09K8/88 , C08G14/12 , E21B33/138
CPC分类号： C09K8/885 , C08G12/40 , C08G12/46 , C09K8/5086
摘要： Aqueous gel-forming compositions are prepared by reacting for 1-10 hours at 50.degree.-95.degree. C., melamine, formaldehyde and a sulfurous acid salt with the optional addition of a gel-modifying agent and/or a gelling agent which is added to the composition immediately prior to use.
摘要翻译： 通过在50-95℃下反应1-10小时，三聚氰胺，甲醛和亚硫酸盐制备水凝胶形成组合物，任选加入凝胶改性剂和/或胶凝剂 在使用前立即使用组合物。
-
公开(公告)号：US5258194A
公开(公告)日：1993-11-02
申请号：US930888
申请日：1992-08-14
摘要： A browning composition is prepared by mixing an oil phase containing an emulsifier with an aqueous phase containing a colorant under shear conditions to form a dispersion of the aqueous phase in the oil phase.
摘要翻译： 通过在剪切条件下将含有乳化剂的油相与含有着色剂的水相混合以形成油相中水相的分散体来制备褐变组合物。
-
4.发明授权Aqueous sulfomethylated melamine gel-forming compositions and methods of use 失效水性磺甲基化三聚氰胺凝胶形成组合物及其使用方法
公开(公告)号：US4821802A
公开(公告)日：1989-04-18
申请号：US239062
申请日：1988-09-01
IPC分类号： C08G12/40 , C08G12/46 , C09K8/508 , C09K8/88 , E21B33/138
CPC分类号： C09K8/885 , C08G12/40 , C08G12/46 , C09K8/5086
摘要： Aqueous gel-forming compositions are prepared by reacting for 1-10 hours at 50.degree.-95.degree. C., melamine, formaldehyde and a sulfurous acid salt with the optional addition of a gel-modifying agent and/or a gelling agent which is added to the composition immediately prior to use.
摘要翻译： 通过在50-95℃下反应1-10小时，三聚氰胺，甲醛和亚硫酸盐制备水凝胶形成组合物，任选加入凝胶改性剂和/或胶凝剂 在使用前立即使用组合物。
-
公开(公告)号：US5139800A
公开(公告)日：1992-08-18
申请号：US608511
申请日：1990-11-02
摘要： There is disclosed a browning composition for uncooked foods comprising a colorant and a fat or an oil. Also disclosed is a process for imparting a brown color to cooked foods by using the composition of the present invention on foods cooked, for example, in a microwave oven.
摘要翻译： 公开了包含着色剂和脂肪或油的未煮过的食品的褐变组合物。 还公开了通过使用本发明的组合物对烹饪的食品例如微波炉中的烹调食物赋予棕色的方法。
-
6.发明授权
公开(公告)号：US4708974A
公开(公告)日：1987-11-24
申请号：US656801
申请日：1984-10-01
摘要： Hydrocarbon recovery from subterranean reservoirs that are penetrated by either injector or producer wells is enhanced by selective permeability modification of the strata of the reservoir with gel-forming phenolic compositions. The injection of the phenolic composition follows a pH sequence specific to the reservoir environment which allows emplacement of the gel-forming composition the desired distance away from the wellbore and production of a uniform gel throughout the treated hydrocarbon-bearing reservoir. The permeability of a treated subterranean reservoir can be restored by treatment of the reservoir with either aqueous hypochlorite or mineral acid.
摘要翻译： 通过用凝胶形成酚类组合物对储层的层的选择性渗透性改性来增强由注入井或生产井渗透的地下储层的烃回收。 酚类组合物的注入遵循对储层环境特异性的pH序列，其允许将凝胶形成组合物置于远离井筒的期望距离并在整个经处理的含烃储层中产生均匀的凝胶。 经处理的地下储层的渗透性可以通过用次氯酸盐水溶液或无机酸处理储层来恢复。
-
-
-
-
-
搜索结果
6 条记录 (耗时 0.027 秒)
