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公开(公告)号：US08808756B2
公开(公告)日：2014-08-19
申请号：US12444800
申请日：2007-10-11
CPC分类号： C04B41/009 , A01N59/20 , C04B20/1066 , C04B22/06 , C04B28/26 , C04B41/52 , C04B2111/00482 , C04B2111/00586 , C04B2111/2092 , C23C24/08 , C23C26/00 , C23C30/00 , E04D7/005 , E04D13/002 , Y10T428/24999 , Y10T428/256 , C04B40/0268 , C04B2103/0016 , C04B2103/67 , C04B41/5006 , C04B41/5033 , C04B41/5037 , C04B41/5075 , C04B41/5089 , C04B41/0072 , C04B41/5001 , C04B41/5041 , C04B41/5049 , A01N2300/00
摘要： The present application is directed to a coating composition comprising a ceramic binder and inorganic copper compound particles. Generally, the inorganic copper compound particles have a median particle size of less than 5 micrometers. In some embodiments, the particles have a median particle size of greater than 1 micrometer. The inorganic copper compound particles may be non-photocatalytic. The coating may also be placed on a structural layer.
摘要翻译： 本申请涉及包含陶瓷粘合剂和无机铜化合物颗粒的涂料组合物。 通常，无机铜化合物颗粒的中值粒径小于5微米。 在一些实施方案中，颗粒具有大于1微米的中值粒度。 无机铜化合物颗粒可以是非光催化的。 涂层也可以放置在结构层上。
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公开(公告)号：US20100098777A1
公开(公告)日：2010-04-22
申请号：US12444800
申请日：2007-10-11
CPC分类号： C04B41/009 , A01N59/20 , C04B20/1066 , C04B22/06 , C04B28/26 , C04B41/52 , C04B2111/00482 , C04B2111/00586 , C04B2111/2092 , C23C24/08 , C23C26/00 , C23C30/00 , E04D7/005 , E04D13/002 , Y10T428/24999 , Y10T428/256 , C04B40/0268 , C04B2103/0016 , C04B2103/67 , C04B41/5006 , C04B41/5033 , C04B41/5037 , C04B41/5075 , C04B41/5089 , C04B41/0072 , C04B41/5001 , C04B41/5041 , C04B41/5049 , A01N2300/00
摘要： The present application is directed to a coating composition comprising a ceramic binder and inorganic copper compound particles. Generally, the inorganic copper compound particles have a median particle size of less than 5 micrometers. In some embodiments, the particles have a median particle size of greater than 1 micrometer. The inorganic copper compound particles may be non-photocatalytic. The coating may also be placed on a structural layer.
摘要翻译： 本申请涉及包含陶瓷粘合剂和无机铜化合物颗粒的涂料组合物。 通常，无机铜化合物颗粒的中值粒径小于5微米。 在一些实施方案中，颗粒具有大于1微米的中值粒度。 无机铜化合物颗粒可以是非光催化的。 涂层也可以放置在结构层上。
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公开(公告)号：US08900194B2
公开(公告)日：2014-12-02
申请号：US10621620
申请日：2003-07-17
申请人： Graham M. Clarke , Michael D. Delmore , Michael K. Domroese , Richard H. Ferber , Jay D. Jacobs , Jamieson C. Keister , Franklyn L. Frederickson
发明人： Graham M. Clarke , Michael D. Delmore , Michael K. Domroese , Richard H. Ferber , Jay D. Jacobs , Jamieson C. Keister , Franklyn L. Frederickson
CPC分类号： A61M37/0015 , A61K9/0021 , A61K9/7023 , A61M2037/0023 , A61M2037/0046 , A61M2205/0244
摘要： Microneedle devices with microneedles having a truncated tapered shape are disclosed. The microneedles of microneedle devices may also have a controlled aspect ratio. Microneedle delivery apparatus are disclosed that include drivers designed to deliver microneedles at velocities that may enhance perforation of the stratum corneum while limiting the sensation of pain experienced at the delivery site.
摘要翻译： 公开了具有截头锥形形状的具有微针的微针装置。 微针装置的微针也可以具有受控的纵横比。 公开了一种微针输送装置，其包括设计成以可以增强角质层穿孔的速度递送微针的驱动器，同时限制在输送部位经历的疼痛的感觉。
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公开(公告)号：US07097853B1
公开(公告)日：2006-08-29
申请号：US08968519
申请日：1997-11-12
IPC分类号： A61M37/00
CPC分类号： A61K9/7053 , A61K9/7061 , C08F290/04 , C09J155/005
摘要： A transdermal drug delivery device involving a macromonomer-containing acrylate or methacrylate copolymer, a softener, and a drug. Also a pressure sensitive skin adhesive involving a macromonomer containing acrylate or methacrylate copolymer and a softener.
摘要翻译： 涉及含有大分子单体的丙烯酸酯或甲基丙烯酸酯共聚物，软化剂和药物的透皮药物递送装置。 也是涉及包含丙烯酸酯或甲基丙烯酸酯共聚物和软化剂的大分子单体的压敏皮肤粘合剂。
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公开(公告)号：US06881203B2
公开(公告)日：2005-04-19
申请号：US09947195
申请日：2001-09-05
申请人： Michael D. Delmore , Patrick R. Fleming , Douglas A. Huntley , Jamieson C. Keister , Cristina U. Thomas , Richard H. Ferber
发明人： Michael D. Delmore , Patrick R. Fleming , Douglas A. Huntley , Jamieson C. Keister , Cristina U. Thomas , Richard H. Ferber
CPC分类号： A61M37/0015 , A61B5/14514 , A61B5/150022 , A61B5/150099 , A61B5/150229 , A61B5/150282 , A61B5/150358 , A61B5/150969 , A61B5/150984 , A61B2562/0295 , A61M2037/0007 , A61M2037/003 , A61M2037/0038 , A61M2037/0053
摘要： Microneedle arrays, methods of manufacturing microneedles and methods of using microneedle arrays. The microneedles in the microneedle arrays may be in the form of tapered structures that include at least one channel formed in the outside surface of each microneedle. The microneedles may have bases that are elongated in one direction. The channels in microneedles with elongated bases may extend from one of the ends of the elongated bases towards the tips of the microneedles. The channels formed along the sides of the microneedles may optionally be terminated short of the tips of the microneedles. The microneedle arrays may also include conduit structures formed on the surface of the substrate on which the microneedle array is located. The channels in the microneedles may be in fluid communication with the conduit structures. One manner of using microneedle arrays of the present invention is in methods involving the penetration of skin to deliver medicaments or other substances and/or extract blood or tissue.
摘要翻译： 微针阵列，制造微针的方法和使用微针阵列的方法。 微针阵列中的微针可以是锥形结构的形式，其包括形成在每个微针的外表面中的至少一个通道。 微针可以具有在一个方向上伸长的基部。 具有细长基座的微针中的通道可以从细长基座的一端延伸到微针的尖端。 沿着微针的侧面形成的通道可以可选地终止于微针的尖端。 微针阵列还可以包括形成在基底上的微针阵列所在的表面上的导管结构。 微针中的通道可以与导管结构流体连通。 使用本发明的微针阵列的一种方式是涉及皮肤渗透以递送药物或其它物质和/或提取血液或组织的方法。
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公开(公告)号：US5403841A
公开(公告)日：1995-04-04
申请号：US108824
申请日：1993-08-18
IPC分类号： A61K9/08 , A61K9/00 , A61K31/53 , A61K47/36 , A61K31/54 , A61K31/415 , A61K31/715
CPC分类号： A61K9/0048 , Y10S514/912
摘要： Topical ophthalmic compositions of carrageenans which are administrable as a drop but which become more viscous or gel upon instillation in the eye are disclosed. Methods for use of the compositions as topical ophthalmic vehicles for pharmaceutically active agents, and alone as lubricants or tear supplements, are also disclosed.
摘要翻译： 公开了角叉菜胶的局部眼用组合物，其可以滴剂施用，但在滴眼时变得更粘或凝胶。 还公开了将组合物用作药物活性剂的局部眼用载体，以及单独用作润滑剂或泪液补充剂的方法。
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7.发明授权Use of monoacyl phosphoglycerides to enhance the corneal penetration of ophthalmic drugs 失效使用单酰基磷酸甘油酯来增强眼药物的角膜渗透
公开(公告)号：US5221696A
公开(公告)日：1993-06-22
申请号：US651886
申请日：1991-02-07
CPC分类号： A61K9/0048 , A61K47/24 , Y10S514/912 , Y10S514/947
摘要： The use of monoacyl phosphoglycerides to enhance the penetration of topically applied ophthalmic drugs through the corneal epithelium is described.
摘要翻译： 描述了使用单酰基磷酸甘油酯来增强局部施用的眼药物穿过角膜上皮的渗透性。
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