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1.发明授权Process for preparing thermosensitive (poly(ethylene oxide) poly(propylene oxide)) derivatives that can be used to functionalize chitosan 有权用于制备可用于官能化壳聚糖的热敏（聚（环氧乙烷）聚（环氧丙烷））衍生物的方法公开(公告)号：US08377418B2
公开(公告)日：2013-02-19
申请号：US12677211
申请日：2008-09-11
CPC分类号： A61L27/52 , A61K8/042 , A61K8/90 , A61K31/722 , A61L27/20 , A61Q19/00 , C08B37/003 , C08G65/331 , C08G65/3324 , C08G65/333 , C08G81/00 , C08G2261/126 , C08G2650/50 , C08J3/075 , C08J2387/00 , C08L5/08 , C08L71/02 , C08L3/00
摘要： The invention relates to a thermosensitive (poly(ethylene oxide) poly(propylene oxide))-acetal derivative, which can be used to functionalize chitosan, and to the process for the preparation thereof. The invention therefore also relates to a process for functionalizing chitosan by grafting this thermosensitive copolymer and optionally another thermosensitive polymer, poly(ethylene oxide). A subject of the invention is also a chitosan-(poly(ethylene oxide) poly(propylene oxide))-poly(ethylene oxide) derivative which has the advantage of being water-soluble at physiological pH. The invention therefore also relates to the aqueous compositions comprising this derivative and to the use of this composition for the manufacture of gel by heating.
摘要翻译： 本发明涉及可用于官能化壳聚糖的热敏（聚（环氧乙烷）聚（环氧丙烷）） - 缩醛衍生物及其制备方法。 因此，本发明还涉及通过接枝该热敏共聚物和任选的另一种热敏聚合物聚（环氧乙烷）官能化壳聚糖的方法。 本发明的主题也是在生理pH下具有水溶性的优点的壳聚糖（聚（环氧乙烷）聚（环氧丙烷）） - 聚（环氧乙烷）衍生物。 因此，本发明还涉及包含该衍生物的水性组合物以及该组合物用于通过加热制造凝胶的用途。
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2.发明申请PROCESS FOR PREPARING THERMOSENSITIVE (POLY(ETHYLENE OXIDE) POLY(PROPYLENE OXIDE)) DERIVATES THAT CAN BE USED TO FUNCTIONALIZE CHITOSAN 有权用于制备可以用于功能化CHITOSAN的热敏性（聚（乙烯氧化物）氧（丙烯氧化物））衍生物的方法公开(公告)号：US20100204177A1
公开(公告)日：2010-08-12
申请号：US12677211
申请日：2008-09-11
CPC分类号： A61L27/52 , A61K8/042 , A61K8/90 , A61K31/722 , A61L27/20 , A61Q19/00 , C08B37/003 , C08G65/331 , C08G65/3324 , C08G65/333 , C08G81/00 , C08G2261/126 , C08G2650/50 , C08J3/075 , C08J2387/00 , C08L5/08 , C08L71/02 , C08L3/00
摘要： The invention relates to a thermosensitive (poly(ethylene oxide) poly(propylene oxide))-acetal derivative, which can be used to functionalize chitosan, and to the process for the preparation thereof. The invention therefore also relates to a process for functionalizing chitosan by grafting this thermosensitive copolymer and optionally another thermosensitive polymer, poly(ethylene oxide). A subject of the invention is also a chitosan-(poly(ethylene oxide) poly(propylene oxide))-poly(ethylene oxide) derivative which has the advantage of being water-soluble at physiological pH. The invention therefore also relates to the aqueous compositions comprising this derivative and to the use of this composition for the manufacture of gel by heating.
摘要翻译： 本发明涉及可用于官能化壳聚糖的热敏（聚（环氧乙烷）聚（环氧丙烷）） - 缩醛衍生物及其制备方法。 因此，本发明还涉及通过接枝该热敏共聚物和任选的另一种热敏聚合物聚（环氧乙烷）官能化壳聚糖的方法。 本发明的主题也是在生理pH下具有水溶性的优点的壳聚糖（聚（环氧乙烷）聚（环氧丙烷）） - 聚（环氧乙烷）衍生物。 因此，本发明还涉及包含该衍生物的水性组合物以及该组合物用于通过加热制造凝胶的用途。
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3.发明授权Amphiphile cyclodextrins, preparation and use thereof for solubilizing organized systems and incorporating hydrophobic molecules 失效两亲环糊精，其制备和用途，用于溶解有组织的体系并掺入疏水性分子公开(公告)号：US06858723B1
公开(公告)日：2005-02-22
申请号：US09926413
申请日：2000-04-26
IPC分类号： A61K47/40 , A61K9/107 , A61K9/127 , A61K9/51 , A61K31/07 , A61K31/164 , A61K31/20 , A61K31/38 , A61K31/7048 , A61K47/48 , A61P3/02 , A61P9/14 , A61P31/04 , C08B37/16 , C08B30/18 , A01N43/04 , A61K31/715
CPC分类号： A61K9/5161 , A61K9/1075 , A61K9/1271 , A61K47/6951 , B82Y5/00 , C08B37/0012
摘要： The invention provides cyclodextrin derivatives that may be used to transport hydrophobic molecules for pharmaceutical or cosmetic applications, by forming organised systems in an aqueous medium, alone or with phospholipids. The cyclodextrin derivatives of the present invention have the formula: in which, R1 represents a steroid, R2 represents an alkyl or aryl group, substituted if applicable, R3 represents H or R2, all the R4 represent OR2, or one of the R4 represents —NHCO(CH2)mCONHR1, m is an integer ranging from 1 to 8, and n is equal to 5, 6 or 7.
摘要翻译： 本发明提供环糊精衍生物，其可用于通过在含水介质中单独或与磷脂形成有组织的系统来输送用于药物或化妆品应用的疏水性分子。 本发明的环糊精衍生物具有下式：其中R 1表示类固醇，R 2表示烷基或芳基，如果适用，R 3代表H或R 2，全部 R 4表示OR 2，或者R 4中的一个表示-NHCO（CH 2）m CONHR 1，m是1至8的整数，n等于5,6或7 。
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4.发明申请Preparation of polysaccharide betainate type compounds, compounds obtained, their use and compositions comprising them 审中-公开制备多糖甜菜碱型化合物，获得的化合物，其用途和包含它们的组合物公开(公告)号：US20070160557A1
公开(公告)日：2007-07-12
申请号：US11724289
申请日：2007-03-15
CPC分类号： A61K8/737 , A61K8/73 , A61K8/731 , A61K8/732 , A61K8/736 , A61K8/738 , A61K2800/5426 , A61Q5/00 , A61Q5/06 , A61Q5/12 , C08B3/14 , C08B31/04 , C08B33/02 , C08B35/02 , C08B37/00
摘要： A process for preparing compounds from the polysaccharide betainate family, novel compounds so obtained, and their use in. cosmetics or in dermatology, as well as the compositions, such as cosmetic or dermatological compositions, comprising said novel compounds.
摘要翻译： 一种从多糖甜菜碱家族制备化合物的方法，如此获得的新化合物及其在化妆品或皮肤病学中的用途，以及包含所述新化合物的组合物，例如化妆品或皮肤病学组合物。
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5.发明授权Preparation of polysaccharide betainate type compounds, compounds obtained, their use and compositions comprising them 失效制备多糖甜菜碱型化合物，获得的化合物，其用途和包含它们的组合物公开(公告)号：US07211268B2
公开(公告)日：2007-05-01
申请号：US10294685
申请日：2002-11-15
CPC分类号： A61K8/737 , A61K8/73 , A61K8/731 , A61K8/732 , A61K8/736 , A61K8/738 , A61K2800/5426 , A61Q5/00 , A61Q5/06 , A61Q5/12 , C08B3/14 , C08B31/04 , C08B33/02 , C08B35/02 , C08B37/00
摘要： A process for preparing compounds from the polysaccharide betainate family, novel compounds so obtained, and their use in cosmetics or in dermatology, as well as the compositions, such as cosmetic or dermatological compositions, comprising said novel compounds.
摘要翻译： 一种从多糖甜菜碱家族制备化合物的方法，如此获得的新化合物及其在化妆品或皮肤病学中的用途，以及包含所述新化合物的组合物，例如化妆品或皮肤病学组合物。
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