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    METHODS AND SYSTEMS FOR LASER TREATMENT USING NON-UNIFORM OUTPUT BEAM
    3.
    发明申请
    METHODS AND SYSTEMS FOR LASER TREATMENT USING NON-UNIFORM OUTPUT BEAM 审中-公开
    使用非均匀输出光束激光治疗的方法和系统

    公开(公告)号：US20130178917A1

    公开(公告)日：2013-07-11

    申请号：US13685199

    申请日：2012-11-26

    申请人： Mirko Georgiev Mirkov ,  Rafael Armando Sierra ,  George E.S. Cho

    发明人： Mirko Georgiev Mirkov ,  Rafael Armando Sierra ,  George E.S. Cho

    IPC分类号： A61N5/06

    CPC分类号： A61N5/0616 ,  A61B18/203 ,  A61B2018/00011 ,  A61B2018/00452 ,  A61B2018/0047 ,  A61B2018/208 ,  A61B2018/2211 ,  G02B5/1885

    摘要： Disclosed herein are methods and systems for treatment, such as skin rejuvenation treatment, use non-uniform laser radiation. A high-intensity portion of the laser radiation causes collagen destruction and shrinkage within select portions of the treatment area, while a lower-intensity portion of the radiation causes fibroblast stimulation leading to collagen production across other portions of the treatment area. An output beam from a laser source, such as an Nd:NAG laser, is coupled into an optical system that modifies the beam to provide a large-diameter beam having a nonuniform energy profile, comprised of a plurality of high-intensity zones surrounded by lower-intensity zones within the treatment beam. The higher-intensity zones heat select portions of the tar et tissue to temperatures sufficient for a first treatment (e.g. collagen shrinkage), while the lower-intensity zones provide sufficient energy for a second treatment (e.g. stimulated collagen production).

    摘要翻译： 本文公开了用于治疗的方法和系统，例如皮肤年轻化治疗，使用不均匀的激光辐射。 激光辐射的高强度部分导致处理区域的选定部分内的胶原蛋白破坏和收缩，而辐射的较低强度部分引起成纤维细胞刺激，导致治疗区域的其它部分的胶原产生。 来自诸如Nd：NAG激光器的激光源的输出光束被耦合到光学系统中，该光学系统修改光束以提供具有不均匀能量分布的大直径光束，所述大直径光束包括被包围的多个高强度区域 处理梁内的较低强度区域。 较高强度区域将焦油和组织的部分热量选择为足以进行第一次处理（例如胶原收缩）的温度，而较低强度区域提供足够的能量进行第二次处理（例如刺激胶原产生）。

    METHODS AND SYSTEMS FOR LASER TREATMENT USING NON-UNIFORM OUTPUT BEAM
    7.
    发明申请
    METHODS AND SYSTEMS FOR LASER TREATMENT USING NON-UNIFORM OUTPUT BEAM 有权
    使用非均匀输出光束激光治疗的方法和系统

    公开(公告)号：US20110152847A1

    公开(公告)日：2011-06-23

    申请号：US12947310

    申请日：2010-11-16

    申请人： Mirko Georgiev Mirkov ,  Rafael Armando Sierra ,  George E.S. Cho

    发明人： Mirko Georgiev Mirkov ,  Rafael Armando Sierra ,  George E.S. Cho

    IPC分类号： A61B18/22 ,  A61B18/20

    CPC分类号： A61N5/0616 ,  A61B18/203 ,  A61B2018/00011 ,  A61B2018/00452 ,  A61B2018/0047 ,  A61B2018/208 ,  A61B2018/2211 ,  G02B5/1885

    摘要： Methods and apparatus for treatment, such as skin rejuvenation treatment, using non-uniform laser radiation. A high-intensity portion of the laser radiation causes collagen destruction and shrinkage within select portions of the treatment area, while a lower-intensity portion of the radiation causes fibroblast stimulation leading to collagen production across other portions of the treatment area. An output beam from a laser source, such as an Nd:YAG laser, is coupled into an optical system that modifies the beam to provide a large-diameter beam having a non-uniform energy profile, comprised of a plurality of high-intensity zones surrounded by lower-intensity zones within the treatment beam. The higher-intensity zones heat select portions of the target tissue to temperatures sufficient for a first treatment (e.g. collagen shrinkage), while the lower-intensity zones provide sufficient energy for a second treatment (e.g. stimulated collagen production). A large area of tissue, preferably 7-10 mm in diameter, can be treated simultaneously, while minimizing the risk of burning or other damage to the skin.In one embodiment, the invention uses a fiber bundle to provide a non-uniform energy output beam. In another embodiment, the invention uses a diffractive lens array to produce the non-uniform output beam. A cooling system can also be integrated with the laser treatment system.

    摘要翻译： 治疗方法和设备，如皮肤嫩肤治疗，使用不均匀的激光辐射。 激光辐射的高强度部分导致处理区域的选定部分内的胶原蛋白破坏和收缩，而辐射的较低强度部分引起成纤维细胞刺激，导致治疗区域的其它部分的胶原产生。 来自激光源（例如Nd：YAG激光器）的输出光束被耦合到光学系统中，该光学系统修改光束以提供具有不均匀能量分布的大直径光束，该光束由多个高强度区域 被处理梁内的低强度区域包围。 较高强度区域将目标组织的部分热量选择为足以进行第一次处理（例如胶原收缩）的温度，而较低强度区域为第二次处理提供足够的能量（例如刺激的胶原产生）。 可以同时治疗大面积的组织，优选直径为7-10mm，同时最小化对皮肤的燃烧或其它损伤的风险。 在一个实施例中，本发明使用纤维束来提供不均匀的能量输出束。 在另一个实施例中，本发明使用衍射透镜阵列来产生不均匀的输出光束。 冷却系统也可以与激光治疗系统集成。

    Method of treatment body tissue using a non-uniform laser beam
    8.
    发明授权
    Method of treatment body tissue using a non-uniform laser beam 有权
    使用不均匀输出光束进行激光治疗的方法和系统

    公开(公告)号：US07856985B2

    公开(公告)日：2010-12-28

    申请号：US11347672

    申请日：2006-02-03

    申请人： Mirko Georgiev Mirkov ,  Rafael Armando Sierra ,  George E. S. Cho

    发明人： Mirko Georgiev Mirkov ,  Rafael Armando Sierra ,  George E. S. Cho

    IPC分类号： A61B19/00

    CPC分类号： A61N5/0616 ,  A61B18/203 ,  A61B2018/00011 ,  A61B2018/00452 ,  A61B2018/0047 ,  A61B2018/208 ,  A61B2018/2211 ,  G02B5/1885

    摘要： Methods and apparatus for treatment, such as skin rejuvenation treatment, using non-uniform laser radiation. A high-intensity portion of the laser radiation causes collagen destruction and shrinkage within select portions of the treatment area, while a lower-intensity portion of the radiation causes fibroblast stimulation leading to collagen production across other portions of the treatment area. An output beam from a laser source, such as an Nd:YAG laser, is coupled into an optical system that modifies the beam to provide a large-diameter beam having a non-uniform energy profile, comprised of a plurality of high-intensity zones surrounded by lower-intensity zones within the treatment beam. The higher-intensity zones heat select portions of the target tissue to temperatures sufficient for a first treatment (e.g. collagen shrinkage), while the lower-intensity zones provide sufficient energy for a second treatment (e.g. stimulated collagen production). A large area of tissue, preferably 7-10 mm in diameter, can be treated simultaneously, while minimizing the risk of burning or other damage to the skin.In one embodiment, the invention uses a fiber bundle to provide a non-uniform energy output beam. In another embodiment, the invention uses a diffractive lens array to produce the non-uniform output beam. A cooling system can also be integrated with the laser treatment system.

    摘要翻译： 治疗方法和设备，如皮肤嫩肤治疗，使用不均匀的激光辐射。 激光辐射的高强度部分导致处理区域的选定部分内的胶原蛋白破坏和收缩，而辐射的较低强度部分引起成纤维细胞刺激，导致治疗区域的其它部分的胶原产生。 来自激光源（例如Nd：YAG激光器）的输出光束被耦合到光学系统中，该光学系统修改光束以提供具有不均匀能量分布的大直径光束，该光束由多个高强度区域 被处理梁内的低强度区域包围。 较高强度区域将目标组织的部分热量选择为足以进行第一次处理（例如胶原收缩）的温度，而较低强度区域为第二次处理提供足够的能量（例如刺激的胶原产生）。 可以同时治疗大面积的组织，优选直径为7-10mm，同时最小化对皮肤的燃烧或其它损伤的风险。 在一个实施例中，本发明使用纤维束来提供不均匀的能量输出束。 在另一个实施例中，本发明使用衍射透镜阵列来产生不均匀的输出光束。 冷却系统也可以与激光治疗系统集成。

    Methods and systems for laser treatment using non-uniform output beam
    9.
    发明授权
    Methods and systems for laser treatment using non-uniform output beam 有权
    使用不均匀输出光束进行激光治疗的方法和系统

    公开(公告)号：US08322348B2

    公开(公告)日：2012-12-04

    申请号：US12947310

    申请日：2010-11-16

    申请人： Mirko Georgiev Mirkov ,  Rafael Armando Sierra ,  George E. S. Cho

    发明人： Mirko Georgiev Mirkov ,  Rafael Armando Sierra ,  George E. S. Cho

    IPC分类号： A61B19/00

    CPC分类号： A61N5/0616 ,  A61B18/203 ,  A61B2018/00011 ,  A61B2018/00452 ,  A61B2018/0047 ,  A61B2018/208 ,  A61B2018/2211 ,  G02B5/1885

    摘要： Methods and apparatus for treatment, such as skin rejuvenation treatment, using non-uniform laser radiation. An output beam from a laser source is coupled into an optical system that modifies the beam to provide a large-diameter beam having a non-uniform energy profile, comprised of a plurality of high-intensity zones surrounded by lower-intensity zones within the treatment beam. A large area of tissue, preferably 7-10 mm in diameter, can be treated simultaneously, while minimizing the risk of burning or other damage to the skin.

    摘要翻译： 治疗方法和设备，如皮肤嫩肤治疗，使用不均匀的激光辐射。 来自激光源的输出光束被耦合到光学系统中，该光学系统修改光束以提供具有不均匀能量分布的大直径光束，所述大直径光束由处理中的较低强度区域包围的多个高强度区域组成 光束。 可以同时治疗大面积的组织，优选直径为7-10mm，同时最小化对皮肤的燃烧或其它损伤的风险。

    Methods And Systems For Laser Treatment Using Non-Uniform Output Beam
    10.
    发明申请
    Methods And Systems For Laser Treatment Using Non-Uniform Output Beam 有权
    使用非均匀输出光束的激光治疗方法和系统

    公开(公告)号：US20100217248A1

    公开(公告)日：2010-08-26

    申请号：US12635295

    申请日：2009-12-10

    申请人： Mirko Georgiev MIRKOV ,  Rafael Armando Sierra ,  George E.S. Cho

    发明人： Mirko Georgiev MIRKOV ,  Rafael Armando Sierra ,  George E.S. Cho

    IPC分类号： A61B18/22 ,  A61B18/20

    CPC分类号： A61N5/0616 ,  A61B18/203 ,  A61B2018/00011 ,  A61B2018/00452 ,  A61B2018/0047 ,  A61B2018/208 ,  A61B2018/2211 ,  G02B5/1885

    摘要： Disclosed herein are methods and systems for treatment, such as skin rejuvenation treatment, use non-uniform laser radiation. A high-intensity portion of the laser radiation causes collagen destruction and shrinkage within select portions of the treatment area, while a lower-intensity portion of the radiation causes fibroblast stimulation leading to collagen production across other portions of the treatment area. An output beam from a laser source, such as an Nd:YAG laser, is coupled into an optical system that modifies the beam to provide a large-diameter beam having a nonuniform energy profile, comprised of a plurality of high-intensity zones surrounded by lower-intensity zones within the treatment beam. The higher-intensity zones heat select portions of the target tissue to temperatures sufficient for a first treatment (e.g. collagen shrinkage), while the lower-intensity zones provide sufficient energy for a second treatment (e.g. stimulated collagen production).

    摘要翻译： 本文公开了用于治疗的方法和系统，例如皮肤年轻化治疗，使用不均匀的激光辐射。 激光辐射的高强度部分导致处理区域的选定部分内的胶原蛋白破坏和收缩，而辐射的较低强度部分引起成纤维细胞刺激，导致治疗区域的其它部分的胶原产生。 来自诸如Nd：YAG激光器的激光源的输出光束被耦合到光学系统中，该光学系统修改光束以提供具有不均匀能量分布的大直径光束，所述大直径光束包括被包围的多个高强度区域 处理梁内的较低强度区域。 较高强度区域将目标组织的部分热量选择为足以进行第一次处理（例如胶原收缩）的温度，而较低强度区域为第二次处理提供足够的能量（例如刺激的胶原产生）。