公开(公告)号：US07223961B2

公开(公告)日：2007-05-29

申请号：US10923239

申请日：2004-08-20

申请人： Holger Birk ,  Volker Seyfried ,  Rafael Storz

发明人： Holger Birk ,  Volker Seyfried ,  Rafael Storz

IPC分类号： G01J3/50 ,  G01J3/28

CPC分类号： G01N21/6458 ,  G01J3/0229 ,  G01J3/14 ,  G01J3/2803 ,  G01J3/36 ,  G01J3/4406

摘要： A device for selectively detecting specific wavelength components of a light beam includes a spectral spreading element for spectrally spreading the light beam, and a detector array arranged downstream of the element. The detector array includes light-insensitive regions and light-sensitive regions. The element and the detector array are matched to each other so that selectable wavelength components of the light beam hit the light-insensitive regions and remaining wavelength components of the light beam hit the light-sensitive regions.

摘要翻译： 用于选择性地检测光束的特定波长分量的装置包括用于光谱扩展光束的光谱扩展元件和布置在元件下游的检测器阵列。 检测器阵列包括光不敏感区域和光敏区域。 元件和检测器阵列彼此匹配，使得光束的可选择的波长分量撞击光不敏感区域，并且光束的剩余波长分量撞击光敏区域。

公开(公告)号：US20060215264A1

公开(公告)日：2006-09-28

申请号：US10568002

申请日：2004-04-02

申请人： Holger Birk ,  Rafael Storz ,  Volker Seyfried

发明人： Holger Birk ,  Rafael Storz ,  Volker Seyfried

IPC分类号： G02B27/28 ,  G02B5/30

CPC分类号： G02B21/26

摘要： An apparatus for detecting photons of a light beam emanating from a spatially limited source includes a detection device having a plurality of detectors forming a three-dimensional array with semitranslucent EMCCDs disposed one behind another. A light splitting device is disposed in a path of rays of the light beam for splitting the light beam so as to distribute the photons over the detectors for detection.

摘要翻译： 用于检测从空间有限的源发出的光束的光子的装置包括具有多个检测器的检测装置，所述检测器形成具有一个彼此设置的半透明EMCCD的三维阵列。 光分离装置设置在光束的光线路径中，用于分离光束，以将光子分布在检测器上用于检测。

公开(公告)号：US20050045812A1

公开(公告)日：2005-03-03

申请号：US10923239

申请日：2004-08-20

申请人： Holger Birk ,  Volker Seyfried ,  Rafael Storz

发明人： Holger Birk ,  Volker Seyfried ,  Rafael Storz

IPC分类号： G01J3/14 ,  G01J3/28 ,  G01J3/36 ,  G01J3/44 ,  G01N21/64 ,  G01J1/42

CPC分类号： G01N21/6458 ,  G01J3/0229 ,  G01J3/14 ,  G01J3/2803 ,  G01J3/36 ,  G01J3/4406

摘要： A device for selectively detecting specific wavelength components of a light beam includes a spectral spreading element for spectrally spreading the light beam, and a detector array arranged downstream of the element. The detector array includes light-insensitive regions and light-sensitive regions. The element and the detector array are matched to each other so that selectable wavelength components of the light beam hit the light-insensitive regions and remaining wavelength components of the light beam hit the light-sensitive regions.

摘要翻译： 用于选择性地检测光束的特定波长分量的装置包括用于光谱扩展光束的光谱扩展元件和布置在元件下游的检测器阵列。 检测器阵列包括光不敏感区域和光敏区域。 元件和检测器阵列彼此匹配，使得光束的可选择的波长分量撞击光不敏感区域，并且光束的剩余波长分量撞击光敏区域。

公开(公告)号：US07259366B2

公开(公告)日：2007-08-21

申请号：US10568002

申请日：2004-04-02

申请人： Holger Birk ,  Rafael Storz ,  Volker Seyfried

发明人： Holger Birk ,  Rafael Storz ,  Volker Seyfried

IPC分类号： H01L31/00

CPC分类号： G02B21/26

摘要： An apparatus for detecting photons of a light beam emanating from a spatially limited source includes a detection device having a plurality of detectors forming a three-dimensional array with semitranslucent EMCCDs disposed one behind another. A light splitting device is disposed in a path of rays of the light beam for splitting the light beam so as to distribute the photons over the detectors for detection.

摘要翻译： 用于检测从空间有限的源发出的光束的光子的装置包括具有多个检测器的检测装置，所述检测器形成具有一个彼此设置的半透明EMCCD的三维阵列。 光分离装置设置在光束的光线路径中，用于分离光束，以将光子分布在检测器上用于检测。

公开(公告)号：US20090059357A1

公开(公告)日：2009-03-05

申请号：US12195871

申请日：2008-08-21

申请人： Rafael STORZ ,  Volker Seyfried

发明人： Rafael STORZ ,  Volker Seyfried

IPC分类号： G02B21/36 ,  G02B21/00

CPC分类号： G02B21/361 ,  G02B6/06

摘要： An optical arrangement having an optical assembly (1) for generating an intermediate image (2) in a beam path is configured and further developed such that an optical element (3) having a plurality of optical waveguides (4) is arranged in the beam bath after the intermediate image (2) to enable the imaging of the intermediate image (2) in a plane on a zone-by-zone or point-by-point basis. Further, a microscope exhibiting such an optical arrangement is specified.

摘要翻译： 具有用于在光束路径中产生中间图像（2）的光学组件（1）的光学装置被配置和进一步显影，使得具有多个光波导（4）的光学元件（3）布置在光束槽 在中间图像（2）之后，以逐区或逐点为基础使平面中的中间图像（2）成像。 此外，规定了显示这种光学布置的显微镜。

公开(公告)号：US20080095200A1

公开(公告)日：2008-04-24

申请号：US11871389

申请日：2007-10-12

申请人： Volker Seyfried ,  Rafael Storz

发明人： Volker Seyfried ,  Rafael Storz

IPC分类号： H01S3/10 ,  H01S3/30

CPC分类号： H01S3/02 ,  G01N21/6458 ,  G01N2201/024 ,  G02B21/0032 ,  H01S3/2383

摘要： A device for generating a laser light beam includes a module. The module includes at least one laser light source, and a mechanical, an electrical and/or an optical interface defined towards an outside of the module.

摘要翻译： 用于产生激光束的装置包括模块。 该模块包括至少一个激光光源，以及朝向模块的外部限定的机械，电和/或光学接口。

公开(公告)号：US20050121603A1

公开(公告)日：2005-06-09

申请号：US10744205

申请日：2003-12-22

申请人： Volker Seyfried ,  Rafael Storz

发明人： Volker Seyfried ,  Rafael Storz

IPC分类号： G02B21/06 ,  G01J3/44 ,  G02B21/00 ,  G02B21/16 ,  H01J3/14 ,  H01J5/16

CPC分类号： G01J3/4406 ,  G02B21/16

摘要： A method for separating different emission wavelengths in a scanning microscope includes scanning a specimen with an illuminating light beam by passing the illuminating light beam over the specimen using a beam deflector, and selectively applying each of a plurality of excitation wavelengths to the illuminating light beam during the scanning according to a predefinable illumination scheme. Emission light coming from the specimen is detected using a detector, the emission light including emission wavelengths corresponding to the excitation wavelengths. The detector is read out when an excitation wavelength is applied so as to provide detected signals. The detected signals are associated with the respective excitation wavelengths using the illumination scheme.

摘要翻译： 用于在扫描显微镜中分离不同发射波长的方法包括使用光束偏转器将照射光束通过样本扫描具有照明光束的样本，并且选择性地将多个激发波长中的每一个施加到照明光束 根据预先确定的照明方案进行扫描。 使用检测器检测来自样本的发射光，发射光包括对应于激发波长的发射波长。 当施加激发波长以便提供检测信号时，检测器被读出。 使用照明方案，检测到的信号与各激发波长相关联。

公开(公告)号：US07835601B2

公开(公告)日：2010-11-16

申请号：US11871389

申请日：2007-10-12

申请人： Volker Seyfried ,  Rafael Storz

发明人： Volker Seyfried ,  Rafael Storz

IPC分类号： G02B6/28 ,  G02B6/36 ,  H01S3/30 ,  H01S3/10

CPC分类号： H01S3/02 ,  G01N21/6458 ,  G01N2201/024 ,  G02B21/0032 ,  H01S3/2383

摘要： A device for generating a laser light beam includes a module. The module includes at least one laser light source, and a mechanical, an electrical and/or an optical interface defined towards an outside of the module.

摘要翻译： 用于产生激光束的装置包括模块。 该模块包括至少一个激光光源，以及朝向模块的外部限定的机械，电和/或光学接口。

公开(公告)号：US07133130B2

公开(公告)日：2006-11-07

申请号：US10458958

申请日：2003-06-11

申请人： Rafael Storz ,  Volker Seyfried

发明人： Rafael Storz ,  Volker Seyfried

IPC分类号： G01J3/30

CPC分类号： G01N21/6458 ,  G01N21/6428 ,  G01N2021/6441 ,  G02B21/0032 ,  G02B21/0044 ,  G02B21/0064 ,  G02B21/0068 ,  G02B21/0076 ,  G02B21/0084 ,  G02B21/0096 ,  G02B21/06 ,  G02B21/16 ,  G02B21/241

摘要： In a method for scanning microscopy an illuminating light beam that contains at least first light of a first wavelength and second light of a second wavelength, is coded. The coded illuminating light beam is directed onto a specimen and detection light proceeding from the specimen is decoded.

公开(公告)号：US07038193B2

公开(公告)日：2006-05-02

申请号：US10744205

申请日：2003-12-22

申请人： Volker Seyfried ,  Rafael Storz

发明人： Volker Seyfried ,  Rafael Storz

IPC分类号： H01J3/14 ,  H01J40/14 ,  H01J5/16 ,  G01J5/02

CPC分类号： G01J3/4406 ,  G02B21/16

摘要： A method for separating different emission wavelengths in a scanning microscope includes scanning a specimen with an illuminating light beam by passing the illuminating light beam over the specimen using a beam deflector, and selectively applying each of a plurality of excitation wavelengths to the illuminating light beam during the scanning according to a predefinable illumination scheme. Emission light coming from the specimen is detected using a detector, the emission light including emission wavelengths corresponding to the excitation wavelengths. The detector is read out when an excitation wavelength is applied so as to provide detected signals. The detected signals are associated with the respective excitation wavelengths using the illumination scheme.

摘要翻译： 用于在扫描显微镜中分离不同发射波长的方法包括使用光束偏转器将照射光束通过样本扫描具有照明光束的样本，并且选择性地将多个激发波长中的每一个施加到照明光束 根据预先确定的照明方案进行扫描。 使用检测器检测来自样本的发射光，发射光包括对应于激发波长的发射波长。 当施加激发波长以便提供检测信号时，检测器被读出。 使用照明方案，检测到的信号与各激发波长相关联。