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12 条记录 (耗时 0.047 秒)

    Method for Identifying Allergenic Proteins And Peptides
    9.
    发明申请
    Method for Identifying Allergenic Proteins And Peptides 有权
    识别过敏原蛋白和肽的方法

    公开(公告)号：US20100143262A1

    公开(公告)日：2010-06-10

    申请号：US12581108

    申请日：2009-10-16

    申请人： Rudolph Valenta ,  Ric Van Tol ,  Udo Herz ,  Heidrun Hochwallner ,  Margarte Focke-Tejkl ,  Ines Swoboda ,  Ulrike Schulmeister

    发明人： Rudolph Valenta ,  Ric Van Tol ,  Udo Herz ,  Heidrun Hochwallner ,  Margarte Focke-Tejkl ,  Ines Swoboda ,  Ulrike Schulmeister

    IPC分类号： A61K49/00 ,  C40B30/06 ,  C07K7/08 ,  C07K14/00 ,  A61K38/08 ,  A61K38/10 ,  A61K38/16 ,  C07K7/06 ,  G01N33/53 ,  A61P37/06

    CPC分类号： G01N33/6854 ,  G01N2500/00 ,  G01N2800/24

    摘要： A method for identifying allergenic proteins and peptides. More specifically, a method for identifying allergenic milk proteins and/or peptides including the steps of: providing at least one expression library comprising DNA or cDNA derived from the mammary gland tissue of a lactating cow, expressing at least one protein or peptide encoded by said expression library, determining the binding capacity of said at least one protein or peptide to IgE of at least one serum of an individual who is sensitive to cow's milk, contacting the at least one protein or peptide exhibiting an IgE binding capacity as determined in step c) with basophil cells, eosinophil cells or mast cells and identifying the at least one protein or peptide as being allergenic when said basophil cells, eosinophil cells or mast cells release upon contact with at least one protein or peptide of step d) at least one mediator.

    摘要翻译： 识别过敏原蛋白和肽的方法。 更具体地，涉及一种用于鉴定过敏性乳蛋白和/或肽的方法，包括以下步骤：提供至少一种表达文库，其包含源自哺乳动物牛乳腺组织的DNA或cDNA，其表达至少一种由所述 表达文库，测定所述至少一种蛋白质或肽与至少一种对牛奶敏感的个体的血清的IgE的结合能力，使与所述至少一种表现IgE结合能力的蛋白质或肽接触，如步骤c ），嗜碱性粒细胞，嗜酸性粒细胞或肥大细胞，并且当所述嗜碱性粒细胞，嗜酸性粒细胞或肥大细胞与步骤d）的至少一种蛋白质或肽接触时释放时，将至少一种蛋白质或肽鉴定为过敏原。至少一种介体 。

    Male germ line cell-specific sequences
    10.
    发明申请
    Male germ line cell-specific sequences 审中-公开
    雄性种系细胞特异性序列

    公开(公告)号：US20050138690A1

    公开(公告)日：2005-06-23

    申请号：US11042574

    申请日：2005-01-24

    申请人： Mohan Singh ,  Prem Bhalla ,  Hui-Ling Xu ,  Ines Swoboda ,  Manjit Singh

    发明人： Mohan Singh ,  Prem Bhalla ,  Hui-Ling Xu ,  Ines Swoboda ,  Manjit Singh

    IPC分类号： C12N15/09 ,  A01H5/00 ,  C07K14/415 ,  C12N5/10 ,  C12N15/29 ,  C12N15/82 ,  A01H1/00 ,  C12N5/04 ,  C12Q1/68

    CPC分类号： C07K14/415 ,  C12N15/8231 ,  C12N15/8289

    摘要： The present invention relates generally to a novel nucleic acid molecule. More particularly, the present invention relates to a male germ line cell specific genetic sequence in plants. Male germ line cells include generative cells and sperm cells. Even more particularly, the present invention provides a male germ line specific gene or functional equivalent thereof. This invention is also directed to the promoter of said gene or its functional derivatives and their use in generating a range of mutant plants including male sterile plants and transposon tagged plants. Preferred nucleic acid molecules of the present invention include the LGC1 gene as well as homologs and derivatives thereof.

    摘要翻译： 本发明一般涉及新的核酸分子。 更具体地说，本发明涉及植物中的雄性种系细胞特异性遗传序列。 雄性生殖细胞包括生殖细胞和精子细胞。 更具体地，本发明提供了雄性种系特异性基因或其功能等同物。 本发明还涉及所述基因的启动子或其功能衍生物及其在产生一系列突变植物（包括雄性不育植物和转座子标记植物）中的用途。 本发明优选的核酸分子包括LGC1基因及其同源物及其衍生物。