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    STABLE NANOPARTICULATE DRUG SUSPENSION
    1.
    发明申请
    STABLE NANOPARTICULATE DRUG SUSPENSION 审中-公开
    稳定的纳米脂肪酸药物悬浮液

    公开(公告)号：US20100323020A1

    公开(公告)日：2010-12-23

    申请号：US12817640

    申请日：2010-06-17

    申请人： Rajeev Gokhale ,  Kennan C. Marsh ,  Yi Shi

    发明人： Rajeev Gokhale ,  Kennan C. Marsh ,  Yi Shi

    IPC分类号： A61K31/5377 ,  A61K9/14 ,  A61P35/04 ,  A61P35/00 ,  A61P7/00

    CPC分类号： A61K9/10 ,  A61K9/0095 ,  A61K31/5377 ,  A61K47/02 ,  A61K47/10

    摘要： A liquid pharmaceutical composition comprises an aqueous medium having suspended therein a solid particulate Bc1-2 family protein inhibitory compound such as ABT-263, having a D90 particle size not greater than about 3 μm; wherein the aqueous medium further comprises at least one pharmaceutically acceptable surfactant and at least one pharmaceutically acceptable basifying agent such as sodium bicarbonate in amounts that are effective together to inhibit particle size increase. The composition is suitable for oral or parenteral administration to a subject in need thereof for treatment of a disease characterized by overexpression of one or more anti-apoptotic Bc1-2 family proteins, for example cancer.

    摘要翻译： 液体药物组合物包含其中悬浮有固体颗粒Bc1-2家族蛋白质抑制化合物如ABT-263的水性介质，其D90粒度不大于约3μm; 其中所述水性介质还包含至少一种药学上可接受的表面活性剂和至少一种药学上可接受的碱化剂如碳酸氢钠，其量可以一起有效抑制粒度增加。 该组合物适合于需要其的受试者口服或肠胃外给药，用于治疗以一种或多种抗凋亡Bc1-2家族蛋白（例如癌症）过表达为特征的疾病。

    CLOUD NUMERICAL CONTROL SYSTEM
    4.
    发明申请
    CLOUD NUMERICAL CONTROL SYSTEM 审中-公开
    数字数控系统

    公开(公告)号：US20150185727A1

    公开(公告)日：2015-07-02

    申请号：US14414903

    申请日：2013-06-08

    申请人： Yi SHI

    发明人： Yi Shi

    IPC分类号： G05B19/418

    CPC分类号： G05B19/418 ,  G05B19/4148 ,  G05B19/4185 ,  G05B2219/31001 ,  G05B2219/31208 ,  G05B2219/31241 ,  G05B2219/31337 ,  G05B2219/32345 ,  Y02P90/04 ,  Y02P90/14 ,  Y02P90/18 ,  Y02P90/20 ,  Y02P90/26 ,  Y02P90/265

    摘要： The invention provides an implementing method of cloud numerical control system. The method implements a numerical control system with functions of online error compensation, CAD/CAPP/CAM/CNC integrating and interactively cooperative assembling machining control. The cloud numerical control system includes a small cloud numerical control system a large cloud numerical control system. The small cloud numerical control system focuses on inside control of a single numerical control machining device and includes a cloud control core node, cloud measure and control subnodes and fine-tuning driving units. The large cloud numerical control system is based on the small cloud numerical control system and performs interactively cooperative machining between multiple numerical control machining devices for different workpieces to be assembled.

    摘要翻译： 本发明提供了云数字控制系统的实现方法。 该方法实现了具有在线误差补偿，CAD / CAPP / CAM / CNC集成和交互协作组装加工控制功能的数控系统。 云数控系统包括一个小云数值控制系统，一个大型云数值控制系统。 小云数控系统侧重于单个数控加工设备的内部控制，包括云控核心节点，云测量控制子节点和微调驱动单元。 大型云数值控制系统基于小云数值控制系统，对不同工件要组装的多台数控加工装置之间进行交互式协同加工。

    Photosensitive Detector with Composite Dielectric Gate MOSFET Structure and Its Signal Readout Method
    5.
    发明申请
    Photosensitive Detector with Composite Dielectric Gate MOSFET Structure and Its Signal Readout Method 有权
    具有复合介电栅极MOSFET结构的光敏检测器及其信号读出方法

    公开(公告)号：US20110215227A1

    公开(公告)日：2011-09-08

    申请号：US13126079

    申请日：2010-02-10

    申请人： Feng Yan ,  Rong Zhang ,  Yi Shi ,  Lin Pu ,  Yue Xu ,  Fuwei Wu ,  Xiaofeng Bo ,  Haoguang Xia

    发明人： Feng Yan ,  Rong Zhang ,  Yi Shi ,  Lin Pu ,  Yue Xu ,  Fuwei Wu ,  Xiaofeng Bo ,  Haoguang Xia

    IPC分类号： H01L31/112 ,  H03F3/08

    CPC分类号： H01L27/14643 ,  H01L27/14614 ,  H01L31/1136

    摘要： The present invention relates to a photosensitive detector with a composite dielectric gate MOSFET structure and its signal readout method. The MOSFET structure detector is formed on a p-type semiconductor substrate. N-type semiconductor regions locate on the two sides of the top part of the p-type semiconductor substrate to form a source and a drain. An underlying dielectric layer, a photo-electron storage layer, a top dielectric layer, and a control gate are stacked on the substrate in sequence. The top insulating dielectric layer can prevent the photoelectrons stored in the photo-electron storage layer from leaking into the control gate. The source and the drain are floating when photoelectrons are collected and injected into the photoelectron storing layer to be held therein. There is a transparent or semi-transparent window for detecting incident light forming on the substrate or gate surface. This invented detector has excellent scalability, basic compatibility with the flash memory fabricating technology, low leakage current, higher imaging speed than CCD, non-sensitivity to processing defects, larger dynamic range than other structures and higher accuracy of signal readout.

    摘要翻译： 本发明涉及一种具有复合介电栅极MOSFET结构的光敏检测器及其信号读出方法。 MOSFET结构检测器形成在p型半导体衬底上。 N型半导体区域位于p型半导体衬底的顶部的两侧，以形成源极和漏极。 依次将基底电介质层，光电子存储层，顶部电介质层和控制栅极堆叠在基板上。 顶部绝缘介电层可以防止存储在光电子存储层中的光电子泄漏到控制栅极中。 当光电子被收集并注入到要保持在其中的光电子储存层时，源极和漏极是浮置的。 存在用于检测基板或栅极表面上的入射光形成的透明或半透明窗口。 本发明的检测器具有优异的可扩展性，与闪存制造技术的基本兼容性，低漏电流，比CCD更高的成像速度，对处理缺陷的灵敏度，对其他结构的动态范围更大，信号读出精度更高。

    Cryptogram lock system with automatically variable true random code tonglingge
    6.
    发明授权
    Cryptogram lock system with automatically variable true random code tonglingge 失效
    密码锁系统具有自动变量真随机代码

    公开(公告)号：US06415386B1

    公开(公告)日：2002-07-02

    申请号：US09230890

    申请日：1999-02-02

    申请人： Yi Shi ,  Weizhi Tan

    发明人： Yi Shi ,  Weizhi Tan

    IPC分类号： G06F704

    CPC分类号： G07C9/00309 ,  G07C2009/00412 ,  G07C2009/005 ,  G07C2009/00761 ,  G07C2009/00793

    摘要： This invention provides an autonomous random dynamic cryptogram lock system which comprises a lock body and a key body. There are non-volatile memories in both the lock body and key body respectively and each memory stores a set of cryptogram corresponding. When unlocking the microprocessor in the lock body checks the cryptograms. If matching, the lock is unlocked, otherwise it gives up alarm. After unlocking, the microprocessor renews a set of the corresponding real random cryptogram in both memories for unlocking next time. It accomplishes one cryptoguard function every time.

    摘要翻译： 本发明提供了一种自主的随机动态密码锁系统，其包括锁体和钥匙体。 锁体和钥匙体分别有非易失性存储器，每个存储器存储一组对应的密码。 当解锁锁体中的微处理器时，会检查密码。 如果匹配，锁定解锁，否则放弃报警。 解锁后，微处理器在两个存储器中更新一组相应的实际随机密码，以便下次解锁。 它每次都完成一个cryptoguard功能。

    OPEN ROOF ASSEMBLY HAVING A DRIVE ASSEMBLY FOR OPERATING A SUNSHADE MEMBER AND A CLOSURE MEMBER SEQUENTIALLY
    7.
    发明申请
    OPEN ROOF ASSEMBLY HAVING A DRIVE ASSEMBLY FOR OPERATING A SUNSHADE MEMBER AND A CLOSURE MEMBER SEQUENTIALLY 审中-公开

    公开(公告)号：US20200254857A1

    公开(公告)日：2020-08-13

    申请号：US16785261

    申请日：2020-02-07

    申请人： Sunny Sun ,  Hardy Shen ,  Yi Shi

    发明人： Sunny Sun ,  Hardy Shen ,  Yi Shi

    IPC分类号： B60J7/043 ,  B60J7/057 ,  B60J7/19

    摘要： An open roof assembly comprises a drive assembly having a slider member. The slider member comprising a coupling member, a first lever member coupled to a sunshade member and a second lever member coupled to a closure member. Each lever member comprises a mating member for coupling with the slider member and a locking lever for releasably engaging a respective locking recess. The slider member is sequentially couplable to one of the lever members. When the slider member is coupled to the first lever member, the sunshade member may be opened or closed by moving the slider member. When the slider member is coupled to the second lever member, the closure member may be opened or closed by moving the slider member.

    CONDUCTIVE POLYMER, SYNTHESIS METHOD THEREOF, AND ELECTROACTIVE ELECTRODE COVERED WITH SAID CONDUCTIVE POLYMER
    10.
    发明申请
    CONDUCTIVE POLYMER, SYNTHESIS METHOD THEREOF, AND ELECTROACTIVE ELECTRODE COVERED WITH SAID CONDUCTIVE POLYMER 有权
    导电聚合物，其合成方法以及覆盖有导电聚合物的电极电极

    公开(公告)号：US20130171338A1

    公开(公告)日：2013-07-04

    申请号：US13819609

    申请日：2011-03-31

    申请人： Lijia Pan ,  Dongyuan Zhai ,  Yi Shi ,  Hao Qiu

    发明人： Lijia Pan ,  Dongyuan Zhai ,  Yi Shi ,  Hao Qiu

    IPC分类号： H01B1/12

    CPC分类号： H01B1/12 ,  C08G61/124 ,  C08G61/126 ,  C08G73/0266 ,  C08J9/283 ,  C08J2201/0504 ,  C08J2205/022 ,  C08J2205/042 ,  C08J2207/00 ,  C08J2365/00 ,  C08K5/09 ,  C08K5/521 ,  H01G11/48 ,  H01M4/1399 ,  H01M4/606 ,  H01M4/608 ,  Y02E60/122 ,  Y02E60/13 ,  Y02P70/54 ,  C08L65/00 ,  C08L79/02

    摘要： The present invention provides a conducting polymer, a synthesis method thereof, and an electroactive electrode covered with the said conducting polymer. The conducting polymer is synthesized as follows: use the polybasic acid as dopant and crosslinking agent, and polymerize monomers into conducting polymer hydrogel. The monomers are selected one or more from pyrrole or its derivatives, thiophene or its derivatives, aniline or its derivatives. The acid group of the polybasic acid contains phosphate or polybasic acid which contains at least two substituents per molecule selected from sulfate, nitrate or carboxylic in which the molecular weight of at least one acid group is no more than 800. The mole ratio of the acid group in polybasic acid to monomers of the conducting polymer is 1:12-12:1. The preparation applied in the invention is simple, and need not to import any impurity. The conducting polymer hydrogel has high ionic conductivity, super hydrophilicity, and good biocompatibility.

    摘要翻译： 本发明提供一种导电聚合物，其合成方法和用所述导电聚合物覆盖的电活性电极。 导电聚合物如下合成：使用多元酸作为掺杂剂和交联剂，并将单体聚合成导电聚合物水凝胶。 单体选自吡咯或其衍生物，噻吩或其衍生物，苯胺或其衍生物中的一种或多种。 多元酸的酸基含有磷酸酯或多元酸，其含有至少两个选自硫酸根，硝酸根或羧酸的分子中的至少两个取代基，其中至少一个酸基的分子量不大于800。酸的摩尔比 多元酸与导电聚合物的单体组成为1：12-12：1。 本发明所用的制剂简单，不需要任何杂质。 导电聚合物水凝胶具有高离子电导率，超亲水性和良好的生物相容性。