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公开(公告)号：US20050272989A1
公开(公告)日：2005-12-08
申请号：US10861837
申请日：2004-06-04
申请人： Rajiv Shah , Bahar Reghabi , Rebecca Gottlieb , Udo Hoss , John Mastrototaro
发明人： Rajiv Shah , Bahar Reghabi , Rebecca Gottlieb , Udo Hoss , John Mastrototaro
CPC分类号： C12Q1/006 , A61B5/14532 , A61B5/1486 , C12Q1/005 , C12Q1/26 , G01N33/4905
摘要： Embodiments of the invention provide analyte sensors having stabilized coating compositions and methods for making and using such sensors. Illustrative embodiments include electrochemical glucose sensors having stabilized glucose oxidase coatings.
摘要翻译： 本发明的实施方案提供了具有稳定的涂料组合物的分析物传感器和用于制造和使用这种传感器 示例性实施方案包括具有稳定的葡萄糖氧化酶涂层的电化学葡萄糖传感器。
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公开(公告)号：US20070079836A1
公开(公告)日：2007-04-12
申请号：US11610269
申请日：2006-12-13
申请人： Bahar Reghabi , Rajiv Shah , Eunjoo Jin , Rebecca Gottlieb , Michael Miller , Nannette Van Antwerp , Bradley Enegren , William Van Antwerp , John Mastrototaro
发明人： Bahar Reghabi , Rajiv Shah , Eunjoo Jin , Rebecca Gottlieb , Michael Miller , Nannette Van Antwerp , Bradley Enegren , William Van Antwerp , John Mastrototaro
IPC分类号： A61B19/00
CPC分类号： A61B5/14532 , A61B5/076 , A61B5/14503 , A61B5/14546 , A61B5/1459 , A61B5/14865 , A61M39/0208
摘要： A reusable analyte sensor site for use with a replaceable analyte sensor for determining a level of an analyte includes a site housing and a resealable insertion site coupled to one end of the site housing. Preferably, the site housing is formed to have an interior cavity, and includes an outer membrane made of a material selected to promote vascularization and having a first pore size, and an inner membrane made of a material selected to be free of tissue ingress. Also, the site housing permits the analyte to pass through the site housing to the interior cavity to permit measurement by the replaceable analyte sensor. The resealable insertion site is provided for inserting the replaceable analyte sensor into the interior cavity of the site housing.
摘要翻译： 与用于确定分析物水平的可更换分析物传感器一起使用的可重复使用的分析物传感器位点包括与站点外壳的一端连接的现场外壳和可重新密封的插入位置。 优选地，所述部位壳体形成为具有内部空腔，并且包括由选择用于促进血管形成并具有第一孔径的材料制成的外膜和由选择为不具有组织进入的材料制成的内膜。 此外，现场外壳允许分析物通过现场外壳进入内腔，以允许通过可更换的分析物传感器进行测量。 可重新密封的插入位置用于将可更换的分析物传感器插入到现场外壳的内部空腔中。
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公开(公告)号：US20110130988A1
公开(公告)日：2011-06-02
申请号：US13004677
申请日：2011-01-11
申请人： RAJIV SHAH , Bahar Reghabi , James L. Henke , Wayne A. Morgan , Gopikrishnan Soundararajan , David Y. Choy , Peter Schultz , Udo Hoss
发明人： RAJIV SHAH , Bahar Reghabi , James L. Henke , Wayne A. Morgan , Gopikrishnan Soundararajan , David Y. Choy , Peter Schultz , Udo Hoss
摘要： A blood glucose sensing system includes a sensor and a sensor electronics device. The sensor includes a plurality of electrodes. The sensor electronics device includes stabilization circuitry. The stabilization circuitry causes a first voltage to be applied to one of the electrodes for a first timeframe and causes a second voltage to be applied to one of the electrodes for a second timeframe. The stabilization circuitry repeats the application of the first voltage and the second voltage to continue the anodic-cathodic cycle. The sensor electronics device may include a power supply, a regulator, and a voltage application device, where the voltage application device receives a regulated voltage from the regulator, applies a first voltage to an electrode for the first timeframe, and applies a second voltage to an electrode for the second timeframe.
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公开(公告)号：US20110101995A1
公开(公告)日：2011-05-05
申请号：US13004660
申请日：2011-01-11
申请人： RAJIV SHAH , Bahar Reghabi , James L. Henke , Wayne A. Morgan , Gopikrishnan Soundararajan , David Y. Choy , Peter Schultz , Udo Hoss
发明人： RAJIV SHAH , Bahar Reghabi , James L. Henke , Wayne A. Morgan , Gopikrishnan Soundararajan , David Y. Choy , Peter Schultz , Udo Hoss
摘要： A blood glucose sensing system includes a sensor and a sensor electronics device. The sensor includes a plurality of electrodes. The sensor electronics device includes stabilization circuitry. The stabilization circuitry causes a first voltage to be applied to one of the electrodes for a first timeframe and causes a second voltage to be applied to one of the electrodes for a second timeframe. The stabilization circuitry repeats the application of the first voltage and the second voltage to continue the anodic-cathodic cycle. The sensor electronics device may include a power supply, a regulator, and a voltage application device, where the voltage application device receives a regulated voltage from the regulator, applies a first voltage to an electrode for the first timeframe, and applies a second voltage to an electrode for the second timeframe.
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公开(公告)号：US08591416B2
公开(公告)日：2013-11-26
申请号：US12887451
申请日：2010-09-21
申请人： Rajiv Shah , Wayne A. Morgan , David Y. Choy , James L. Henke , Bahar Reghabi , Gopikrishnan Soundararajan , Peter Schultz , Udo Hoss
发明人： Rajiv Shah , Wayne A. Morgan , David Y. Choy , James L. Henke , Bahar Reghabi , Gopikrishnan Soundararajan , Peter Schultz , Udo Hoss
CPC分类号： G01N27/403 , A61B5/14532 , A61B5/1473 , A61B2560/0223 , A61B2562/02 , C12Q1/006 , G01N27/327 , G01N27/416
摘要： A sensor system includes a sensor and a sensor electronics device. The sensor includes a plurality of electrodes. The sensor electronics device includes a connection detection device, a power source, and a delay circuit. The connection detection device determines if the sensor electronics device is connected to the sensor and transmits a connection signal. The delay circuit receives the connection signal, waits a preset hydration time, and couples the regulated voltage from the power source to an electrode in the sensor after the preset hydration time has elapsed. Alternatively, the sensor electronics device may include an electrical detection circuit and a microcontroller. The electrical detection circuit determines if the plurality of electrodes are hydrated and generates an interrupt if the electrodes are hydrated. A microcontroller receives the interrupt and transmits a signal representative of a voltage to an electrode of the plurality of electrodes.
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公开(公告)号：US20110106480A1
公开(公告)日：2011-05-05
申请号：US13004631
申请日：2011-01-11
申请人： RAJIV SHAH , Bahar Reghabi , James L. Henke , Wayne A. Morgan , Gopikrishnan Soundararajan , David Y. Choy , Peter Schultz , Udo Hoss
发明人： RAJIV SHAH , Bahar Reghabi , James L. Henke , Wayne A. Morgan , Gopikrishnan Soundararajan , David Y. Choy , Peter Schultz , Udo Hoss
摘要： A blood glucose sensing system includes a sensor and a sensor electronics device. The sensor includes a plurality of electrodes. The sensor electronics device includes stabilization circuitry. The stabilization circuitry causes a first voltage to be applied to one of the electrodes for a first timeframe and causes a second voltage to be applied to one of the electrodes for a second timeframe. The stabilization circuitry repeats the application of the first voltage and the second voltage to continue the anodic-cathodic cycle. The sensor electronics device may include a power supply, a regulator, and a voltage application device, where the voltage application device receives a regulated voltage from the regulator, applies a first voltage to an electrode for the first timeframe, and applies a second voltage to an electrode for the second timeframe.
摘要翻译： 血糖感测系统包括传感器和传感器电子设备。 传感器包括多个电极。 传感器电子设备包括稳定电路。 稳定电路使得第一电压被施加到第一时间帧中的一个电极，并且使得第二电压被施加到第二时间范围中的一个电极。 稳定电路重复施加第一电压和第二电压以继续阳极 - 阴极循环。 传感器电子设备可以包括电源，调节器和电压施加装置，其中电压施加装置从调节器接收调节电压，在第一时间帧向电极施加第一电压，并施加第二电压 第二时间段的电极。
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公开(公告)号：US20110048938A1
公开(公告)日：2011-03-03
申请号：US12887465
申请日：2010-09-21
申请人： RAJIV SHAH , Wayne A. Morgan , David Y. Choy , James L. Henke , Bahar Reghabi , Gopikrishnan Soundararajan , Peter Schultz , Udo Hoss
发明人： RAJIV SHAH , Wayne A. Morgan , David Y. Choy , James L. Henke , Bahar Reghabi , Gopikrishnan Soundararajan , Peter Schultz , Udo Hoss
IPC分类号： G01N27/403
CPC分类号： G01N27/403 , A61B5/14532 , A61B5/1473 , A61B2560/0223 , A61B2562/02 , C12Q1/006 , G01N27/327 , G01N27/416
摘要： A sensor system includes a sensor and a sensor electronics device. The sensor includes a plurality of electrodes. The sensor electronics device includes a connection detection device, a power source, and a delay circuit. The connection detection device determines if the sensor electronics device is connected to the sensor and transmits a connection signal. The delay circuit receives the connection signal, waits a preset hydration time, and couples the regulated voltage from the power source to an electrode in the sensor after the preset hydration time has elapsed. Alternatively, the sensor electronics device may include an electrical detection circuit and a microcontroller. The electrical detection circuit determines if the plurality of electrodes are hydrated and generates an interrupt if the electrodes are hydrated. A microcontroller receives the interrupt and transmits a signal representative of a voltage to an electrode of the plurality of electrodes.
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公开(公告)号：US20110010105A1
公开(公告)日：2011-01-13
申请号：US12887460
申请日：2010-09-21
申请人： RAJIV SHAH , Wayne A. Morgan , David Y. Choy , James L. Henke , Bahar Reghabi , Gopikrishnan Soundararajan , Peter Schultz , Udo Hoss
发明人： RAJIV SHAH , Wayne A. Morgan , David Y. Choy , James L. Henke , Bahar Reghabi , Gopikrishnan Soundararajan , Peter Schultz , Udo Hoss
CPC分类号： G01N27/403 , A61B5/14532 , A61B5/1473 , A61B2560/0223 , A61B2562/02 , C12Q1/006 , G01N27/327 , G01N27/416
摘要： A sensor system includes a sensor and a sensor electronics device. The sensor includes a plurality of electrodes. The sensor electronics device includes a connection detection device, a power source, and a delay circuit. The connection detection device determines if the sensor electronics device is connected to the sensor and transmits a connection signal. The delay circuit receives the connection signal, waits a preset hydration time, and couples the regulated voltage from the power source to an electrode in the sensor after the preset hydration time has elapsed. Alternatively, the sensor electronics device may include an electrical detection circuit and a microcontroller. The electrical detection circuit determines if the plurality of electrodes are hydrated and generates an interrupt if the electrodes are hydrated. A microcontroller receives the interrupt and transmits a signal representative of a voltage to an electrode of the plurality of electrodes.
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公开(公告)号：US20070173712A1
公开(公告)日：2007-07-26
申请号：US11322977
申请日：2005-12-30
申请人： Rajiv Shah , Bahar Reghabi , James L. Henke , Wayne A. Morgan , Gopikrishnan Soundararajan , David Y. Choy , Peter Schultz , Udo Hoss
发明人： Rajiv Shah , Bahar Reghabi , James L. Henke , Wayne A. Morgan , Gopikrishnan Soundararajan , David Y. Choy , Peter Schultz , Udo Hoss
摘要： A blood glucose sensing system includes a sensor and a sensor electronics device. The sensor includes a plurality of electrodes. The sensor electronics device includes stabilization circuitry. The stabilization circuitry cases a first voltage to be applied to one of the electrodes for a first timeframe and causes a second voltage to be applied to one of the electrodes for a second timeframe. The stabilization circuitry repeats the application of the first voltage and the second voltage to continue the anodic-cathodic cycle. The sensor electronics device may include a power supply, a regulator, and a voltage application device, where the voltage application device receives a regulator voltage from the regulator, applies a first voltage to an electrode for the first timeframe, and applies a second voltage to an electrode for the second timeframe.
摘要翻译： 血糖感测系统包括传感器和传感器电子设备。 传感器包括多个电极。 传感器电子设备包括稳定电路。 稳定电路将第一时间帧施加到电极中的一个施加第一电压，并且将第二电压施加到第二时间框架中的一个电极。 稳定电路重复施加第一电压和第二电压以继续阳极 - 阴极循环。 传感器电子设备可以包括电源，调节器和电压施加装置，其中电压施加装置从调节器接收调节器电压，在第一时间帧向电极施加第一电压，并将第二电压施加到 第二时间段的电极。
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公开(公告)号：US20110125447A1
公开(公告)日：2011-05-26
申请号：US13004691
申请日：2011-01-11
申请人： Rajiv Shah , Bahar Reghabi , James L. Henke , Wayne A. Morgan , Gopikrishnan Soundararajan , David Y. Choy , Peter Schultz , Udo Hoss
发明人： Rajiv Shah , Bahar Reghabi , James L. Henke , Wayne A. Morgan , Gopikrishnan Soundararajan , David Y. Choy , Peter Schultz , Udo Hoss
摘要： A blood glucose sensing system includes a sensor and a sensor electronics device. The sensor includes a plurality of electrodes. The sensor electronics device includes stabilization circuitry. The stabilization circuitry causes a first voltage to be applied to one of the electrodes for a first timeframe and causes a second voltage to be applied to one of the electrodes for a second timeframe. The stabilization circuitry repeats the application of the first voltage and the second voltage to continue the anodic-cathodic cycle. The sensor electronics device may include a power supply, a regulator, and a voltage application device, where the voltage application device receives a regulated voltage from the regulator, applies a first voltage to an electrode for the first timeframe, and applies a second voltage to an electrode for the second timeframe.
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