摘要:
The disclosure relates to methods of imaging a portion of a body vessel using magnetic resonance imaging (MRI), methods of performing interventional medical treatment under MRI, interventional medical devices, such as wire guides, useful in performing treatment under MRI, and methods of making interventional medical devices. A method of imaging a portion of a body vessel of a patient using MRI includes advancing through a body vessel an end of a wire guide comprising a continuous metal core member and a continuous jacket disposed over the entire core member through a body vessel and scanning the portion of the patient that is positioned within an MRI scanner and that includes a portion of the body vessel within which the end of the wire guide is disposed. A secondary medical device, such as a catheter, can be disposed over the wire guide and manipulated in the method.
摘要:
The disclosure relates to support frames for prosthetic implantable valves. The support frames may include a plurality of symmetrically arrayed interconnected U-shaped member structures. Preferred support frames are tubular structures enclosing a longitudinal axis and including a plurality of U-shaped member structures facing a distal or a proximal end of the support frame. Each U-shaped member structure may be connected to a single longitudinally adjacent U-shaped member facing in an opposite longitudinal direction, as well as two laterally adjacent U-shaped members.
摘要:
The present disclosure describes an implantable branched vessel prosthesis, such as a prosthetic valve, having both a radially expandable annular portion and a laterally extendable branch portion. Methods of delivering the branched vessel prosthesis to a branched body vessel are also provided, as well as delivery systems comprising the branched vessel prosthesis. The branched vessel prostheses are useful, for example, as implantable prosthetic venous valves for treating venous valve insufficiency. The delivery system is configured to deploy independently both the annular portion within a primary vessel and the branch portion within a branch vessel with only one delivery system.
摘要:
Prosthetic medical devices with delayed valve function and in situ remodeling of a portion thereof are provided, as well as methods of manufacturing the medical devices and methods of treatment using the medical devices. The medical devices may be adapted to initially maintain a remodelable material within a body vessel in a first configuration suitable to contact the remodelable material with a body fluid contacting the remodelable material for a first time period or a second configuration adapted to regulate the flow of body fluid contacting the remodelable material. The medical devices may include a releasable holding member configured to retain the remodelable material in the first configuration.
摘要:
A device for implantation in a body vessel is provided. The device includes a frame that accommodates dynamic variation in the size of the vessel. At least one leaflet is attached to the frame. The leaflet is deformable between a first position allowing fluid flow in a first, antegrade direction and a second position restricting fluid flow in a second, retrograde direction. Methods for delivering the device to a body vessel and methods and kits for treating a subject using such a device are also provided.
摘要:
Medical devices for implantation in a body vessel, and methods of using and making the same, are provided. A medical device includes a support frame having struts and a weakened frame portion, and a remodelable material tensionably attached to the support frame. The weakened frame portion has a first configuration in which the support frame has a first outward radial force and a second configuration in which the support frame has a second, lesser outward radial force. The remodelable material restricts expansion of the frame from a radially compressed configuration to a radially expanded configuration when the weakened frame portion is in the first configuration. The remodelable material can form one or more valve leaflets adapted to regulate fluid flow in a body vessel, such as a vein.
摘要:
Among other things, there are disclosed apparatuses and methods for medically sealing an opening in a vessel or wall. For example, in medical applications, a delivery tube is provided for insertion through a sheath into a vessel (e.g. a blood vessel). A dome-shaped seal fixed to a filament, an absorbent and/or compressible buffer, and a locking member are provided in the delivery tube. The delivery tube is configured so that it can be inserted into the vessel through a sheath. Tension is maintained on the filament to hold the seal against the tube or sheath. The sheath is pulled out, which pulls out the tube at the same time, leaving the seal over the opening in the vessel wall. The locking member compresses the buffer against the outside of the vessel and with the filament holds the seal in place against the inside of a vessel.
摘要:
Described are devices, methods, and systems useful for deploying one or more occlusive prostheses within the vasculature of a patient. Illustrative devices can include a deployment tube or sheath that contains an occlusive prosthesis, wherein a segment of the sheath is reversible by a user so as to deploy the prosthesis from the sheath lumen within a bodily lumen of a patient.
摘要:
A method for open surgical repair of a damaged portion of an artery or vein. A tubular medical assembly may include one or more shaped members, such as microbarbs, configured to anchor into the tunica intima and the tunica media of the vessel wall, and not to the tunic adventitia and vasa vasorum. The medical assembly is delivered to the damaged vessel portion via a delivery device through an open air pathway, and forms a conduit between transected ends of the damaged vessel.
摘要:
The disclosure relates to an expandable valve prosthesis for regulating flow through a body vessel. The prosthesis comprises a frame configured to form a laterally asymmetric partial sinus and a valve member.