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公开(公告)号：US07790876B2
公开(公告)日：2010-09-07
申请号：US10538590
申请日：2003-12-19
IPC分类号： C07H21/04 , A61K39/135
CPC分类号： C12Q1/6883 , C07H21/04 , C12N2770/32111
摘要： Methods and materials for the detection of the foot and mouth disease virus (FMDV). The methods may utilize PCR amplification, with or without an internal positive control, and appropriate primer pairs. The reagents to perform these methods can be supplied as a kit and/or in tablet form.
摘要翻译： 用于检测口蹄疫病毒（FMDV）的方法和材料。 该方法可以利用具有或不具有内部阳性对照的PCR扩增和适当的引物对。 执行这些方法的试剂可以作为试剂盒和/或片剂形式提供。
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公开(公告)号：US20080032285A1
公开(公告)日：2008-02-07
申请号：US10538590
申请日：2003-12-19
CPC分类号： C12Q1/6883 , C07H21/04 , C12N2770/32111
摘要： Methods and materials for the detection of the foot and mouth disease virus (FMDV). The methods may utilize PCR amplification, with or without an internal positive control, and appropriate primer pairs. The reagents to perform these methods can be supplied as a kit and/or in tablet form.
摘要翻译： 用于检测口蹄疫病毒（FMDV）的方法和材料。 该方法可以利用具有或不具有内部阳性对照的PCR扩增和适当的引物对。 执行这些方法的试剂可以作为试剂盒和/或片剂形式提供。
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公开(公告)号：US20110020794A1
公开(公告)日：2011-01-27
申请号：US12501527
申请日：2009-07-13
申请人： LAURA A. BEDZYK , Daniel R. Demarco , Richard C. Ebersole , Raymond E. Jackson , Stephen Varkey , Rick Ye
发明人： LAURA A. BEDZYK , Daniel R. Demarco , Richard C. Ebersole , Raymond E. Jackson , Stephen Varkey , Rick Ye
IPC分类号： C12Q1/68
CPC分类号： C12Q1/68 , C12Q1/689 , C12Q2600/158
摘要： Methods for the direct detection of diagnostic target RNA have been developed, which obviate the need for time consuming RNA purification and isolation procedures.
摘要翻译： 已经开发了用于直接检测诊断靶RNA的方法，其消除了对时间的RNA纯化和分离程序的需要。
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公开(公告)号：US07732142B2
公开(公告)日：2010-06-08
申请号：US11840261
申请日：2007-08-17
CPC分类号： C12Q1/701
摘要： Primers have been isolated that are diagnostic for the detection of the infectious hypodermal and hematopoietic necorsis virus (IHHNV). The primers are based on a new portion of the IHHNV genome and may be used in primer directed amplification or nucleic acid hybridization assay methods.
摘要翻译： 已经分离了用于检测感染性皮下和造血Necorsis病毒（IHHNV）的引物。 引物基于IHHNV基因组的新部分，并且可以用于引物定向扩增或核酸杂交测定方法。
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公开(公告)号：US20080166722A1
公开(公告)日：2008-07-10
申请号：US11873497
申请日：2007-10-17
CPC分类号： C12Q1/689
摘要： Primers have been isolated that are diagnostic for the detection of Vibrio harveyi. The primers are based on a portion of the Vibrio harveyi LuxR gene and may be used in primer directed amplification or nucleic acid hybridization assay methods.
摘要翻译： 已经分离了用于检测哈氏弧菌的引物。 这些引物是基于一部分的哈氏弧菌（Luxor）基因，可用于引物定向扩增或核酸杂交测定方法。
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公开(公告)号：US06511809B2
公开(公告)日：2003-01-28
申请号：US09858994
申请日：2001-05-16
IPC分类号： C12Q168
CPC分类号： C12Q1/6804 , C12Q2521/501 , C12Q2563/179
摘要： A process is disclosed for the detection of an analyte utilizing a nucleic acid label as a reporter. The analyte is detected by the binding of at least two reporter conjugates, each conjugate comprising a member of a binding pair and a nucleic acid label. The binding of the reporter conjugates to the analyte facilitates the juxtaposition of the nucleic acid labels, forming a single nucleic acid amplicon. The amplicon may then be detected directly, or may be used as a template of the generation of amplification products. Detection of the analyte by this process significantly reduces assay background caused by non-specific reporter conjugate binding.
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7.发明授权
公开(公告)号：US5578460A
公开(公告)日：1996-11-26
申请号：US424753
申请日：1995-04-18
IPC分类号： C12Q1/24 , G01N27/447 , C12Q1/02 , C12N13/00
CPC分类号： C12Q1/24 , G01N27/44704 , G01N27/44765
摘要： The present invention sorts microorganism populations from a mixture which contains more than one microorganism population. Microorganisms of different types vary in size, shape, and surface charge characteristics. These characteristics we believe contribute to the rate of migration for microorganisms under the influence of an electric field. Microorganisms of the same population (genus and species) will migrate similarly. By applying an electric field in a direction opposite the direction of fluid flow, separation is enhanced.
摘要翻译： 本发明从含有多于一个微生物种群的混合物中分选微生物种群。 不同类型的微生物在尺寸，形状和表面电荷特性上都有所不同。 我们认为这些特征有助于微电子在电场影响下的迁移速率。 同一群体（属和种）的微生物将同样迁移。 通过沿与流体流动方向相反的方向施加电场，分离增强。
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公开(公告)号：US4940760A
公开(公告)日：1990-07-10
申请号：US418007
申请日：1989-10-06
摘要： Group Transfer Polymerization (GTP) process for preparing a "living" polymer, the process comprising contacting under polymerizing conditions in a polymerization medium, at least one acrylic or maleimide monomer with an initiator which is a tetracoordinate organosilicon, organotin or organogermanium compound having at least one GTP initiating site and a catalyst which is or is a source of an anion selected from the group consisting of bifluoride, fluoride, cyanide, azide or a selected oxyanion, or a selected Lewis acid or Lewis base, the process further characterized in that the initiator or the anion or Lewis acid catalyst is chemically attached (grafted) to a solid support that is insoluble in the polymerization medium.
摘要翻译： 用于制备“活性”聚合物的组转移聚合（GTP）方法，该方法包括在聚合条件下在聚合介质中，至少一种丙烯酸或马来酰亚胺单体与引发剂接触，所述引发剂是四配位有机硅，有机锡或有机锗化合物，至少具有 一个GTP起始位点和一种催化剂，其是选自二氟化物，氟化物，氰化物，叠氮化物或选择的氧阴离子或选择的路易斯酸或路易斯碱的阴离子的来源，其进一步的特征在于， 引发剂或阴离子或路易斯酸催化剂化学连接（接枝）到不溶于聚合介质的固体载体上。
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公开(公告)号：US4704198A
公开(公告)日：1987-11-03
申请号：US604586
申请日：1984-04-27
IPC分类号： C08F2/00 , C07K1/26 , C08F2/46 , C08F2/54 , C08F20/52 , C08F220/00 , C08F220/56 , G01N27/447 , B01D13/02 , C08F20/56 , G01N27/40 , G03C5/00
CPC分类号： G01N27/44704 , G01N27/44747 , Y10S522/91
摘要： Describes a process for controlling the polymerization and cross-linked density of electrophoretic gel products useful for separation of bioorganic molecules, which process does not use initiators common to processes of the art. Electron beam polymerized gels afford the desired advantages of being ultra thin and having a high electrophoretic resolution with programmable porosity profiles.
摘要翻译： 描述了一种用于控制用于分离生物有机分子的电泳凝胶产物的聚合和交联密度的方法，该方法不使用本领域工艺通用的引发剂。 电子束聚合凝胶提供了超薄的所需优点，并且具有高的电泳分辨率和可编程的孔隙率分布。
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公开(公告)号：US07951540B2
公开(公告)日：2011-05-31
申请号：US12707762
申请日：2010-02-18
CPC分类号： C12Q1/689
摘要： Primers have been isolated that are diagnostic for the detection of Vibrio harveyi. The primers are based on a portion of the Vibrio harveyi LuxR gene and may be used in primer directed amplification or nucleic acid hybridization assay methods.
摘要翻译： 已经分离了用于检测哈氏弧菌的引物。 这些引物是基于一部分的哈氏弧菌（Luxor）基因，可用于引物定向扩增或核酸杂交测定方法。
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