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1.发明授权Blood processing systems and methods which optically monitor incremental platelet volumes in a plasma constituent 有权血液处理系统和光学监测血浆成分中血小板增加量的方法公开(公告)号：US06312607B1
公开(公告)日：2001-11-06
申请号：US09419727
申请日：1999-10-16
申请人： Richard I Brown , John T Foley , Timothy J Patno
发明人： Richard I Brown , John T Foley , Timothy J Patno
IPC分类号： B01D1712
CPC分类号： B01D21/26 , A61M1/30 , A61M1/302 , A61M1/303 , A61M1/308 , A61M1/3693 , A61M1/3696 , A61M2202/0427 , A61M2205/331 , A61M2205/50 , B01D17/0217 , B01D21/0003 , B01D21/2405 , B01D21/245 , B01D21/262 , B01D21/32 , B01D2221/08 , B01D2221/10 , B04B5/0442 , B04B13/00 , A61M2202/0071
摘要： Blood processing systems and methods separate blood into constituents including a plasma constituent that includes a platelet volume. The systems and methods detect the optical density of the plasma constituent and generate a first output indicative of the optical density. A processing element integrates the first output relative to the volume of plasma constituent and generates an integrated output. The integrated output correlates to the platelet volume. A second processing element generates an output based, at least in part, upon the integrated output, which comprises a value indicating a blood volume that needs be processed to obtain a desired platelet volume.
摘要翻译： 血液处理系统和方法将血液分成包括血小板体积的血浆成分的成分。 系统和方法检测等离子体成分的光密度并产生表示光密度的第一输出。 处理元件将第一输出相对于等离子体成分的体积积分并产生积分输出。 综合输出与血小板体积相关。 第二处理元件至少部分地基于积分输出生成输出，其包括指示需要处理以获得期望的血小板体积的血液体积的值。
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2.发明授权Blood collection systems and methods that derive estimated effects upon the donor's blood volume and hematocrit 有权血液收集系统和方法可以推测出对捐献者的血量和血细胞比容的影响公开(公告)号：US06730054B2
公开(公告)日：2004-05-04
申请号：US09789183
申请日：2001-02-20
IPC分类号： A61M3700
CPC分类号： A61M1/3693 , A61M1/02 , A61M1/0209 , A61M1/0222 , A61M1/302 , A61M1/303 , A61M1/308 , A61M1/3603 , A61M1/3633 , A61M1/3696 , A61M1/385 , A61M2202/0427 , A61M2202/0429 , A61M2205/33 , A61M2205/3393 , A61M2205/60 , A61M2230/207 , A61M2202/0014 , A61M2202/0021
摘要： Blood processing systems and methods convey blood drawn from a donor through a blood processing circuit to separate the blood into at least one targeted blood component for collection. The systems and methods derive an estimated effect of the procedure upon the donor. The estimated effect can be expressed in terms of a net blood fluid volume loss, or as a hematocrit of the donor after completion of the desired blood collection procedure. The systems and methods present the estimated effect to an operator for viewing, reading, or offloading.
摘要翻译： 血液处理系统和方法通过血液处理电路传送从供体抽出的血液，以将血液分离成至少一个目标血液成分用于收集。 这些系统和方法可以估计给予者的程序效应。 估计的效果可以表示为净血液体积损失，或作为所需血液收集程序完成后供体的血细胞比容。 系统和方法对运营商提供了查看，阅读或卸载的估计效果。
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3.发明授权Blood processing systems and methods which optically derive the volume of platelets contained in a plasma constituent 失效血液处理系统和光学导出血浆成分中所含的血小板体积的方法
公开(公告)号：US5958250A
公开(公告)日：1999-09-28
申请号：US896665
申请日：1997-07-18
申请人： Richard I Brown , John T Foley , Kyungyoon Min , Mark Sahlin
发明人： Richard I Brown , John T Foley , Kyungyoon Min , Mark Sahlin
IPC分类号： G01N33/49 , A61B5/145 , A61K35/14 , A61M1/02 , A61M1/36 , A61P7/00 , B01D17/02 , B01D17/12 , B01D21/24 , B01D21/26 , B04B5/04 , B04B13/00 , G01N21/35
CPC分类号： B01D17/0217 , A61M1/3693 , A61M1/3696 , B01D21/003 , B01D21/2405 , B01D21/245 , B01D21/262 , B01D21/32 , B04B13/00 , B04B5/0442 , A61M2202/0427 , A61M2205/331 , B01D2221/10
摘要： Blood processing systems and methods separate blood into constituents including a plasma constituent that includes a platelet volume. The systems and methods detect the optical density of the plasma constituent and generate a first output indicative of the optical density. A processing element integrates the first output relative to the volume of plasma constituent and generates an integrated output. The integrated output correlates to the platelet volume. A second processing element generates a third output based, at least in part, upon the integrated output, which comprises parameters for storing the platelet volume.
摘要翻译： 血液处理系统和方法将血液分成包括血小板体积的血浆成分的成分。 系统和方法检测等离子体成分的光密度并产生表示光密度的第一输出。 处理元件将第一输出相对于等离子体成分的体积积分并产生积分输出。 综合输出与血小板体积相关。 第二处理元件至少部分地基于集成输出产生第三输出，其包括用于存储血小板体积的参数。
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4.发明授权Blood processing systems and methods which optically monitor plasma opacity 有权血液处理系统和光学监测等离子体不透明度的方法公开(公告)号：US06183651B2
公开(公告)日：2001-02-06
申请号：US09382893
申请日：1999-08-25
申请人： Richard I Brown , John T Foley , Kyungyoon Min , Mark Sahlin
发明人： Richard I Brown , John T Foley , Kyungyoon Min , Mark Sahlin
IPC分类号： B01D1712
CPC分类号： B01D17/0217 , A61M1/3693 , A61M1/3696 , A61M2202/0427 , A61M2205/331 , B01D21/003 , B01D21/2405 , B01D21/245 , B01D21/26 , B01D21/262 , B01D21/32 , B01D2221/10 , B04B5/0442 , B04B13/00 , A61M2202/0071
摘要： Blood processing systems and methods separate blood into constituents including a plasma constituent that includes a platelet volume. The systems and methods detect the optical density of the plasma constituent and generate a first output indicative of the optical density. A processing element integrates the first output relative to the volume of plasma constituent and generates an integrated output. The integrated output correlates to the platelet volume. A second processing element generates a third output based, at least in part, upon the integrated output, which comprises parameters for storing the platelet volume.
摘要翻译： 血液处理系统和方法将血液分成包括血小板体积的血浆成分的成分。 系统和方法检测等离子体成分的光密度并产生表示光密度的第一输出。 处理元件将第一输出相对于等离子体成分的体积积分并产生积分输出。 综合输出与血小板体积相关。 第二处理元件至少部分地基于集成输出产生第三输出，其包括用于存储血小板体积的参数。
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公开(公告)号：US5980757A
公开(公告)日：1999-11-09
申请号：US922880
申请日：1997-09-03
申请人： Richard I Brown , John T Foley , Kyungoon Min , Mark Sahlin
发明人： Richard I Brown , John T Foley , Kyungoon Min , Mark Sahlin
CPC分类号： B01D21/262 , B04B13/00 , B04B5/0442 , G01F23/292 , B01D2221/08 , B01D2221/10 , B04B2013/006
摘要： A viewing area in a blood separation chamber is monitored for the presence of an interface region between plasma and cellular blood components. Sensed optical density values for the viewing area are compared to a calibrated threshold value to generate a time pulse output. A calibration element derives the calibrated threshold value based upon either (i) a comparison of a sensed reference optical density value in the viewing area to an expected optical density value for the reference material, or (ii) a sensed optical density value of plasma exiting the blood separation chamber, or both.
摘要翻译： 监测血液分离室中的观察区域是否存在血浆和细胞血液成分之间的界面区域。 将观察区域的感测光密度值与校准的阈值进行比较以产生时间脉冲输出。 校准元件基于（i）将观察区域中的感测参考光密度值与参考材料的预期光密度值进行比较，或（ii）等离子体出射的感测光密度值 血液分离室，或两者。
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