摘要:
Processing chamber for use with apheresis devices are described herein. An example centrifugal processing chamber includes first and second lateral walls spaced at a distance from one another. Additionally, the example centrifugal processing chamber includes a channel at least partially defined by the first and second lateral walls. Further, the centrifugal processing chamber includes an inlet fluidly coupled to the channel to convey blood to the channel. Further still, the centrifugal processing chamber includes a first outlet fluidly coupled to the channel having a first opening adjacent the first lateral wall. The first outlet is to convey separated plasma from the channel. Additionally, the centrifugal processing chamber includes a second fluid outlet fluidly coupled to the channel having a second opening adjacent the second lateral wall. The second outlet is to convey separated red blood cells from the channel. Additionally, the processing chamber includes a barrier formed along the second lateral wall to intercept platelets. The first and second lateral walls are spaced such that the distance between the first and second lateral walls enables at least one therapeutic unit of single dose platelets to pool adjacent the barrier without spilling into the first outlet or the second outlet.
摘要:
Blood processing systems and methods convey whole blood from a donor into a centrifugal separation device for separation into red blood cells and a plasma constituent. The plasma constituent and red blood cells are removed from the separation device at least in part while whole blood is conveyed into the separation device. The systems and methods generate, at least in part while whole blood is conveyed into the separation device and plasma constituent and red blood cells are removed from the separation device, a control command affecting separation within the separation device based, at least in part, upon a factor representing hematocrit of red blood cells separated in the separation device.
摘要:
A method of processing blood establishes communication between a donor and a blood flow path and pumps whole blood from the donor into a container through the blood flow path. The method centrifugally separates the whole blood in the container into concentrated red blood cells and a plasma constituent. After the method interrupts communication between the donor and the blood flow path, the method pumps the concentrated red blood cells from the container to mix the concentrated red blood cells with a nutritive solution to restore the hematocrit of the concentrated red blood cells to a desired value. The method also removes the plasma constituent.
摘要:
Automated systems and methods for withdrawing a selected compound from blood are disclosed. The systems and methods utilize a disposable fluid circuit mounted on a re-usable hardware component or module. The system withdraws blood from a donor or patient, separates the blood into two or more components and further combines the separated component with a solvent so as to remove a compound from the blood component.
摘要:
A chamber for use in a rotating field to separate blood components is described. An inlet port near one end of the chamber introduces blood into the chamber for flow circumferentially about the rotational axis toward the opposite end of the chamber for separation into at least one blood component. At least one outlet port is juxtaposed next to the inlet port near the one end of the chamber for conveying one separated blood component from the channel. The chamber directs the one separated blood component to a collection region near the opposite end of the chamber. An enclosed interior collection passage within the channel leads from the collection region and directs the one collected component to the outlet port for transport from the chamber.
摘要:
A mouthpiece for use with breathing devices of the type used by scuba divers is provided. The mouthpiece includes-at least one no-return valve to allow exhalation directly into the ambient environment. Additional no-return valves can be incorporated into the inhalation pathway to prevent fluids from flowing back into the regulator housing. In one embodiment, an inlet no-return valve is located in the respiratory port tube of the regulator. In other embodiments, an inlet no-return valve is located in the mouthpiece itself. The disclosed invention keeps the interior spaces of the regulator clean and dry even when the regulator is not in place, thus extending regulator life and preventing a dangerous and irritating free-flow condition from occurring due to icing during cold water use. Saliva and expired air with its attendant moistures and pathogenic entities are prevented from entering the regulator housing. The mouthpiece is easily detachable and can be sanitized between uses, making it particularly well suited for rental and instructional purposes. The mouthpiece can be variously constructed to differentiate common-use mouthpieces from those owned individually.
摘要:
Blood processing systems and methods separate whole blood into red blood cells and a plasma constituent within a rotating centrifugal separation device. The systems and methods convey whole blood into the separation device through an inlet path including a pump operable at a prescribed rate. The systems and methods remove plasma constituent from the separation device through an outlet path including a pump operable at a prescribed rate. The systems and methods derive a value H.sub.b representing an apparent hematocrit of whole blood entering the separation device, where: ##EQU1## and where H.sub.rbc is a value relating to hematocrit of red blood cells in the separation device. The systems and methods generate outputs and control commands based, at least in part, upon H.sub.b.
摘要:
Systems and methods convey anticoagulated blood suspension from a donor into a separation device for component separation. One or more components are retained for therapeutic use, while one or more are returned to the donor. The systems and methods monitor the rate at which anticoagulant carried in the returned components is being returned. The rate, expressed in terms of milligram (mg) of anticoagulant per kilogram (kg) of donor body weight per unit of time of blood processing, is compared to a nominal rate that is correlated with donor comfort.
摘要:
A centrifuge comprising a yoke element that rotates about a rotational axis and a processing chamber having an axis. The processing chamber includes a bowl element, a spool element, and a mechanism for joining the spool and bowl elements for relative movement between a mutually cooperating position for centrifugal processing and a mutually separated position for loading. A hinge attaches the processing chamber to the yoke element for pivotal movement between an operating position and an access position. In the operating position, the spool and bowl elements are in their mutually cooperating position and oriented for rotation with the yoke element about the rotational axis. In the access position, the processing chamber axis lies outside the axis of rotation and the spool and bowl elements are oriented for movement from their mutually cooperating position into their mutually separated position.
摘要:
A peristaltic pumping apparatus and associated method to control power to the pump rotor to establish, during a preestablished first time period, a selected first angular velocity and sequentially establishing during a preestablished second time period immediately following the first time period a second angular velocity different than the first angular velocity. In this fashion, the apparatus and method achieve flow rates well below the minimum continuous flow rate of the rotor.