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公开(公告)号:US07914460B2
公开(公告)日:2011-03-29
申请号:US11504335
申请日:2006-08-15
申请人: Richard J. Melker , David G. Bjoraker , Donn M. Dennis , Jon D. Stewart , Christopher D. Batich , Matthew M. Booth , John Frederick Horn, Jr. , Ronald E. Youngblood
发明人: Richard J. Melker , David G. Bjoraker , Donn M. Dennis , Jon D. Stewart , Christopher D. Batich , Matthew M. Booth , John Frederick Horn, Jr. , Ronald E. Youngblood
CPC分类号: A61B5/083 , A61B5/1486 , A61B5/413 , Y10T436/144444
摘要: The present invention provides systems and methods for analyzing glucose present in exhaled breath condensate (EBC). In certain embodiments of the invention, electrochemical- or coulometric-based sensing technologies are used to analyze EBC for the presence and/or concentration of glucose.
摘要翻译: 本发明提供了用于分析呼出气凝缩物(EBC)中存在的葡萄糖的系统和方法。 在本发明的某些实施方案中,使用电化学或基于库仑的感测技术来分析葡萄糖的存在和/或浓度。
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公开(公告)号:US20080045825A1
公开(公告)日:2008-02-21
申请号:US11504335
申请日:2006-08-15
申请人: Richard J. Melker , David G. Bjoraker , Donn M. Dennis , Jon D. Stewart , Christopher D. Batich , Matthew M. Booth , John Frederick Horn , Ronald E. Youngblood
发明人: Richard J. Melker , David G. Bjoraker , Donn M. Dennis , Jon D. Stewart , Christopher D. Batich , Matthew M. Booth , John Frederick Horn , Ronald E. Youngblood
IPC分类号: A61B5/00
CPC分类号: A61B5/083 , A61B5/1486 , A61B5/413 , Y10T436/144444
摘要: The present invention provides systems and methods for analyzing glucose present in exhaled breath condensate (EBC). In certain embodiments of the invention, electrochemical- or coulometric-based sensing technologies are used to analyze EBC for the presence and/or concentration of glucose.
摘要翻译: 本发明提供了用于分析呼出气凝缩物(EBC)中存在的葡萄糖的系统和方法。 在本发明的某些实施方案中,使用电化学或基于库仑的感测技术来分析葡萄糖的存在和/或浓度。
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公开(公告)号:US20100216175A1
公开(公告)日:2010-08-26
申请号:US12374564
申请日:2007-08-15
申请人: Richard J. Melker , David G. Bjoraker , Donn Michael Dennis , Jon Dale Stewart , Christopher D. Batich , Matthew M. Booth , John Frederick Horn , Ronald Youngblood , Timothy E. Morey
发明人: Richard J. Melker , David G. Bjoraker , Donn Michael Dennis , Jon Dale Stewart , Christopher D. Batich , Matthew M. Booth , John Frederick Horn , Ronald Youngblood , Timothy E. Morey
IPC分类号: C12Q1/54 , C12M1/34 , G01N33/497 , G01N27/26
CPC分类号: A61B5/083 , A61B5/1486 , A61B5/413 , Y10T436/144444
摘要: Systems and methods for analyzing glucose present in exhaled breath condensate (EBC). In certain embodiments, electrochemical- or coulometnc-based sensing technologies are used to analyze EBC for the presence and/or concentration of glucose. Based on the detected glucose m EBC, the subject invention provides systems and methods for non-invasive, accurate assessment of blood glucose levels.
摘要翻译: 用于分析呼出气凝缩物(EBC)中存在的葡萄糖的系统和方法。 在某些实施方案中,使用基于电化学或库仑法的感测技术来分析葡萄糖的存在和/或浓度。 基于检测到的葡萄糖EBC,本发明提供了用于非侵入性,准确评估血糖水平的系统和方法。
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公开(公告)号:US08211035B2
公开(公告)日:2012-07-03
申请号:US11512856
申请日:2006-08-29
CPC分类号: A61M16/01 , A61B5/082 , A61B5/14532 , A61B5/14546 , A61B5/411 , A61B5/4821 , A61B5/7267 , A61M16/0051 , A61M16/026 , A61M16/0808 , A61M16/0841 , A61M16/1045 , A61M16/18 , A61M16/22 , A61M2016/0036 , A61M2016/1035 , A61M2202/0275 , A61M2202/0486 , A61M2205/18 , A61M2205/3553 , A61M2205/3561 , A61M2205/3584 , A61M2205/52 , A61M2205/80 , A61M2230/43 , A61M2230/432 , A61M2230/435 , A61M2230/437 , G01N33/497
摘要: The present invention includes systems and methods for monitoring endogenous compound concentration in blood by detecting markers, such as odors, upon exhalation by a patient, wherein such markers are the endogenous compound itself or result from the endogenous compound. In the case of olfactory markers, the invention preferably utilizes electronic sensor technology, such as the commercial devices referred to as “artificial” or “electronic” noses or tongues, to non-invasively monitor endogenous compound levels in blood. The invention further includes a reporting system capable of tracking endogenous compound concentrations in blood (remote or proximate locations) and providing the necessary alerts with regard to emergent or harmful conditions in a patient.
摘要翻译: 本发明包括通过在患者呼出时检测诸如气味等标记物的血液中的内源性化合物浓度的系统和方法,其中所述标志物是内源性化合物本身或由内源化合物产生。 在嗅觉标记的情况下,本发明优选利用诸如称为“人造”或“电子”鼻子或舌头的商业装置的电子传感器技术非侵入性地监测血液中的内源性化合物水平。 本发明还包括能够跟踪血液中的内源性化合物浓度(偏远或近处)并提供关于患者的紧急或有害状况的必要警报的报告系统。
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公开(公告)号:US20120016252A1
公开(公告)日:2012-01-19
申请号:US13246436
申请日:2011-09-27
IPC分类号: A61B5/08
CPC分类号: A61M16/01 , A61B5/082 , A61B5/14532 , A61B5/14546 , A61B5/411 , A61B5/4821 , A61B5/7267 , A61M16/0051 , A61M16/026 , A61M16/0808 , A61M16/0841 , A61M16/1045 , A61M16/18 , A61M16/22 , A61M2016/0036 , A61M2016/1035 , A61M2202/0275 , A61M2202/0486 , A61M2205/18 , A61M2205/3553 , A61M2205/3561 , A61M2205/3584 , A61M2205/52 , A61M2205/80 , A61M2230/43 , A61M2230/432 , A61M2230/435 , A61M2230/437 , G01N33/497
摘要: The present invention includes systems and methods for monitoring endogenous compound concentration in blood by detecting markers, such as odors, upon exhalation by a patient, wherein such markers are the endogenous compound itself or result from the endogenous compound. In the case of olfactory markers, the invention preferably utilizes electronic sensor technology, such as the commercial devices referred to as “artificial” or “electronic” noses or tongues, to non-invasively monitor endogenous compound levels in blood. The invention further includes a reporting system capable of tracking endogenous compound concentrations in blood (remote or proximate locations) and providing the necessary alerts with regard to emergent or harmful conditions in a patient.
摘要翻译: 本发明包括通过在患者呼出时检测诸如气味等标记物的血液中的内源性化合物浓度的系统和方法,其中所述标志物是内源性化合物本身或由内源化合物产生。 在嗅觉标记的情况下,本发明优选利用诸如称为“人造”或“电子”鼻子或舌头的商业装置的电子传感器技术非侵入性地监测血液中的内源性化合物水平。 本发明还包括能够跟踪血液中的内源性化合物浓度(偏远或近处)并提供关于患者的紧急或有害状况的必要警报的报告系统。
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6.
公开(公告)号:US07104963B2
公开(公告)日:2006-09-12
申请号:US10054619
申请日:2002-01-22
CPC分类号: A61B5/4821 , A61B5/082 , A61B5/0836 , A61B5/7264
摘要: A method and system is provided for detecting the depth of anesthesia wherein at least one anesthetic agent is absorbed in a patient's bloodstream during the administration of anesthesia, which includes sampling a patient's expired breath; analyzing the breath for concentration of at least one substance indicative of the anesthetic agent using sensor technology such as free (unmetabolized) anesthetic agent or its metabolites; determining the effect of the agent based on that concentration; and determining depth of anesthesia based thereon. The method also detects endogenous compounds such as ketones and ammonia in exhaled breath as well as other pathologic organisms.
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