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公开(公告)号：US09216286B2
公开(公告)日：2015-12-22
申请号：US13265098
申请日：2010-04-28
CPC分类号： A61N1/08 , A61B90/39 , A61B2090/3966 , A61N1/05 , A61N1/0551 , A61N1/086 , A61N1/3718 , A61N1/3752 , A61N2001/058 , A61N2001/0582 , A61N2001/086 , Y10T29/49016 , Y10T29/49117 , Y10T29/4921 , Y10T29/49227 , Y10T29/49826
摘要： Implantable medical leads include a shield that is guarded at a termination by having a first portion and second portion of the shield, where the first portion is between a termination of the shield at the second portion and an inner insulation layer surrounding the filars. The first portion may reduce the coupling of RF energy from the termination of the shield at the second portion to the filars. The first and second portions may be part of a continuous shield, where the first and second portions are separated by an inversion of the shield. The first and second portions may instead be separate pieces. The first portion may be noninverted residing between the termination at the second portion and inner layers, or the first portion may be inverted to create first and second sub-portions. The shield termination at the second portion is between the first and second sub-portions.
摘要翻译： 可植入医疗引线包括通过具有屏蔽件的第一部分和第二部分在端子处被保护的屏蔽件，其中第一部分位于第二部分处的屏蔽件的终端和围绕线圈的内部绝缘层之间。 第一部分可以减少RF能量从第二部分处的屏蔽端接到丝状体的耦合。 第一和第二部分可以是连续屏蔽的一部分，其中第一和第二部分被屏蔽的反转分开。 第一和第二部分可以是分开的部分。 第一部分可以位于第二部分的终端和内层之间，或者第一部分可以被倒置以产生第一和第二子部分。 第二部分处的屏蔽终端位于第一和第二子部分之间。
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2.发明授权公开(公告)号：US08588914B2
公开(公告)日：2013-11-19
申请号：US11450127
申请日：2006-06-09
IPC分类号： A61N1/375
CPC分类号： A61N1/375 , A61N1/0504 , A61N1/0531 , A61N1/0534 , A61N1/0553 , A61N1/36071 , A61N1/3756
摘要： An implantable medical device (IMD) with a housing and electrodes on at least two surfaces of the housing is described. The surfaces may be, for example, opposed, substantially parallel surfaces, e.g., top and bottom surfaces. Location of electrodes on multiple surfaces of the housing may allow the IMD to deliver stimulation to a variety of tissues and with a variety of current field configurations. For example, the IMD may deliver peripheral nerve field stimulation (PNFS) to one or more tissue areas via electrodes selected from one or both of the surfaces to, for example, reduce the sensation of pain in a tissue area proximate to an implantation site of the IMD without targeting a specific nerve. The IMD may be implanted between or within intra-dermal, deep dermal, or subcutaneous layers of the tissue of the patient to deliver PNFS to any one or more of these layers.
摘要翻译： 描述了在壳体的至少两个表面上具有壳体和电极的可植入医疗装置（IMD）。 表面可以是例如相对的基本上平行的表面，例如顶部和底部表面。 电极在壳体的多个表面上的位置可以允许IMD将刺激递送到各种组织以及各种当前的现场配置。 例如，IMD可以通过选自一个或两个表面的电极将外周神经区域刺激（PNFS）递送到一个或多个组织区域，以例如减少接近植入部位的组织区域中的疼痛感觉 IMD没有针对特定的神经。 IMD可以植入在患者组织的真皮内，深层皮肤或皮下层之间或内，以将PNFS递送到这些层中的任何一个或多个层。
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3.发明授权Electrical and activation field models for programming a stimulation lead with complex electrode array geometry 有权用于通过复杂电极阵列几何编程刺激引线的电和激活场模型公开(公告)号：US08452415B2
公开(公告)日：2013-05-28
申请号：US11591187
申请日：2006-10-31
IPC分类号： A61N1/08
CPC分类号： A61N1/0529 , A61N1/0531 , A61N1/0534 , A61N1/0553 , A61N1/36071 , A61N1/36082 , A61N1/36185 , A61N1/37247
摘要： The disclosure is directed to programming implantable stimulators to deliver stimulation energy via one or more implantable leads having complex electrode array geometries. A programmer is configured to generate an electrical field model from selected stimulation parameters and patient anatomy data. The electrical field model indicates how the electrical field propagation would occur in the patient during therapy. In addition, the programmer may be configured to generate an activation field model from the electrical field model and a neuron model. The activation field indicates which neurons within the electrical field will be activated during the therapy. Either of these field models may be presented to the user via a user interface that also displays a representation of the lead implanted within the patient. The user interface may allow the user to adjust the stimulation therapy by manipulating displayed field or activation model representations.
摘要翻译： 本公开涉及编程可植入刺激器以通过具有复杂电极阵列几何形状的一个或多个可植入引线输送刺激能量。 编程器被配置为从所选择的刺激参数和患者解剖数据生成电场模型。 电场模型指示治疗期间患者的电场传播如何发生。 此外，程序员可以被配置为从电场模型和神经元模型生成激活场模型。 激活区域指示在治疗期间电场内的哪些神经元将被激活。 这些现场模型中的任一个可以经由还显示植入患者体内的引线的表示的用户界面呈现给用户。 用户界面可以允许用户通过操纵显示的场或激活模型表示来调整刺激疗法。
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公开(公告)号：US20120316619A1
公开(公告)日：2012-12-13
申请号：US13592918
申请日：2012-08-23
IPC分类号： A61N1/36
CPC分类号： A61N1/0534 , A61N1/36071 , A61N1/36157 , A61N1/36185 , A61N1/37247
摘要： The disclosure is directed to programming implantable stimulators to deliver stimulation energy via one or more implantable leads having complex electrode array geometries. The disclosure also contemplates guided programming to select electrode combinations and parameter values to support efficacy. The techniques may be applied to a programming interface associated with a clinician programmer, a patient programmer, or both. A user interface permits a user to view electrodes from different perspectives relative to the lead. For example, the user interface provides a side view of a lead and a cross-sectional view of the lead. The user interface may include an axial control medium to select and/or view electrodes at different axial positions along the length of a lead, and a rotational control medium to select and/or view electrodes at different angular positions around a circumference of the lead.
摘要翻译： 本公开涉及编程可植入刺激器以通过具有复杂电极阵列几何形状的一个或多个可植入引线输送刺激能量。 本公开还考虑了引导编程以选择电极组合和参数值以支持功效。 这些技术可以应用于与临床医生程序员，患者程序员或两者相关联的编程接口。 用户界面允许用户从相对于铅的不同角度来观察电极。 例如，用户界面提供引线的侧视图和引线的横截面图。 用户界面可以包括轴向控制介质，用于选择和/或查看沿引线长度的不同轴向位置处的电极;以及旋转控制介质，用于选择和/或查看围绕引线圆周的不同角位置处的电极。
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公开(公告)号：US20120035696A1
公开(公告)日：2012-02-09
申请号：US13264179
申请日：2010-04-27
申请人： Michael J. Kern , James M. Olsen , Michael R. Klardie , Richard T. Stone , Chad Q. Cai , Spencer M. Bondhus , Mark J. Conroy , Timothy R. Abraham , Brian T. Stolz
发明人： Michael J. Kern , James M. Olsen , Michael R. Klardie , Richard T. Stone , Chad Q. Cai , Spencer M. Bondhus , Mark J. Conroy , Timothy R. Abraham , Brian T. Stolz
CPC分类号： A61N1/08 , A61B90/39 , A61B2090/3966 , A61N1/05 , A61N1/0551 , A61N1/086 , A61N1/3718 , A61N1/3752 , A61N2001/058 , A61N2001/0582 , A61N2001/086 , Y10T29/49016 , Y10T29/49117 , Y10T29/4921 , Y10T29/49227 , Y10T29/49826
摘要： A shield located within an implantable medical lead may be terminated in various ways. The shield may be terminated by butt, scarf, lap, or other joints between insulation layers surrounding the lead and an insulation extension. For lap joints, a portion of an outer insulation layer may be removed and a replacement outer insulation layer is positioned in place of the removed outer insulation layer, where the replacement layer extends beyond an inner insulation layer and the shield. The replacement layer may also lap onto a portion of the insulation extension. Barbs may be located between the replacement layer and the inner insulation layer or the insulation extension. The shield wires have ends at the termination point that may be folded over individually or may be capped with a ring located within one of the insulation layers of the jacket.
摘要翻译： 位于可植入医疗引线内的护罩可以以各种方式终止。 护罩可以通过对接，围巾，搭接或围绕导线的绝缘层与绝缘延伸部分之间的其他接头来终止。 对于搭接接头，可以去除外部绝缘层的一部分，并且替换外部绝缘层被定位成代替去除的外部绝缘层，其中替换层延伸超出内部绝缘层和屏蔽。 替换层也可以搭接在绝缘延伸部分的一部分上。 倒钩可以位于替换层和内绝缘层之间或绝缘延伸部分之间。 屏蔽线在终止点处具有可以单独折叠的端部，或者可以用位于护套的绝缘层之一内的环来封盖。
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公开(公告)号：US20110056076A1
公开(公告)日：2011-03-10
申请号：US12948592
申请日：2010-11-17
申请人： Michael Hegland , Richard T. Stone
发明人： Michael Hegland , Richard T. Stone
IPC分类号： H01R43/16
CPC分类号： A61N1/0551 , A61B5/0422 , A61B2562/125 , B29C45/14639 , B29L2031/753 , Y10T29/49117 , Y10T29/49151 , Y10T29/49169 , Y10T29/49176 , Y10T29/49181 , Y10T29/49204 , Y10T29/4922
摘要： A method of manufacturing a segmented electrode assembly. An electrically conducting tube is coupled to an electrically insulating material. The tube is generally cylindrical and hollow and defines one or more gaps at a first axial position. The tube also includes one or more bridges located at a second axial position. The method includes removing at least a portion of the bridge resulting in a segmented electrode assembly having at least one segment. A number embodiments of making a tube are also provided. In another embodiment a method of manufacturing a medical lead using a segmented electrode assembly is provided.
摘要翻译： 一种制造分段电极组件的方法。 导电管耦合到电绝缘材料。 管通常为圆柱形且中空并且在第一轴向位置限定一个或多个间隙。 管还包括位于第二轴向位置的一个或多个桥。 该方法包括去除桥的至少一部分，产生具有至少一个段的分段电极组件。 还提供了制造管的多个实施例。 在另一个实施例中，提供了使用分段电极组件制造医疗引线的方法。
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7.发明授权Programming interface with a concentric axial view of a stimulation lead with complex electrode array geometry 有权具有复杂电极阵列几何形状的刺激引线的同心轴视图的编程界面公开(公告)号：US07848802B2
公开(公告)日：2010-12-07
申请号：US11591280
申请日：2006-10-31
IPC分类号： A61N1/08
CPC分类号： A61N1/37247 , A61N1/36007 , A61N1/36071 , A61N1/36082 , A61N1/36185
摘要： The disclosure is directed to programming implantable stimulators to deliver stimulation energy via one or more implantable leads having complex electrode array geometries. The disclosure also contemplates guided programming to select electrode combinations and parameter values to support efficacy. The techniques may be applied to a programming interface associated with a clinician programmer, a patient programmer, or both. A user interface permits a user to view electrodes from different perspectives relative to the lead. For example, the user interface provides a side view of a lead and a concentric axial view of the lead. The user interface may include an axial control medium to select and/or view electrodes at different axial positions along the length of a lead, and a rotational control medium to select and/or view electrodes at different angular positions around a circumference of the lead.
摘要翻译： 本公开涉及编程可植入刺激器以通过具有复杂电极阵列几何形状的一个或多个可植入引线输送刺激能量。 本公开还考虑了引导编程以选择电极组合和参数值以支持功效。 这些技术可以应用于与临床医生程序员，患者程序员或两者相关联的编程接口。 用户界面允许用户从相对于铅的不同角度来观察电极。 例如，用户界面提供引线的侧视图和引线的同心轴向视图。 用户界面可以包括轴向控制介质，用于选择和/或查看沿引线长度的不同轴向位置处的电极;以及旋转控制介质，用于选择和/或查看围绕引线圆周的不同角位置处的电极。
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公开(公告)号：US07826902B2
公开(公告)日：2010-11-02
申请号：US11591178
申请日：2006-10-31
IPC分类号： A61N1/00
CPC分类号： A61N1/0529 , A61N1/0531 , A61N1/0534 , A61N1/0553 , A61N1/3605 , A61N1/36082 , A61N1/37247
摘要： The disclosure describes a method and system that allows a user to configure electrical stimulation therapy by defining a stimulation field. After a stimulation lead is implanted in a patient, a clinician manipulates a stimulation field on the display to encompass desired anatomical regions of the patient. In this manner, the clinician determines which anatomical regions to stimulate, and the system generates the necessary stimulation parameters. In some cases, a lead icon representing the implanted lead is displayed to show the clinician where the lead is relative to anatomical regions of the patient.
摘要翻译： 本公开描述了允许用户通过定义刺激场来配置电刺激治疗的方法和系统。 在刺激引线植入患者体内之后，临床医生操纵显示器上的刺激场以包围病人的所需解剖区域。 以这种方式，临床医生确定要刺激的解剖区域，并且系统产生必要的刺激参数。 在一些情况下，显示代表植入引线的引线图标，以显示临床医师，其中引线相对于患者的解剖区域。
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9.发明授权公开(公告)号：US07822483B2
公开(公告)日：2010-10-26
申请号：US11591299
申请日：2006-10-31
IPC分类号： A61N1/00
CPC分类号： A61N1/37247 , A61N1/0529 , A61N1/0531 , A61N1/0534 , A61N1/0551 , A61N1/36082
摘要： The disclosure describes a method and system that generates an electrical field model of defined stimulation therapy and displays the electrical field model to a user via a user interface. The electrical field model is generated based upon a patient anatomy and stimulation parameters to illustrate which areas of a patient anatomical region will be covered by the electrical field during therapy. In addition, a neuron model may be applied to the electrical field model to generate an activation field model. The activation field model indicates which neurons will be activated by the electrical field in the anatomical region. These field models may be used by a clinician to determine effective therapy prior to stimulation delivery. In particular, the field models may be beneficial when programming non axi-symmetric, or three-dimensional (3D), leads which allow greater flexibility in creating stimulation fields.
摘要翻译： 本公开描述了一种产生定义的刺激疗法的电场模型并通过用户界面向用户显示电场模型的方法和系统。 基于患者解剖学和刺激参数产生电场模型，以说明在治疗期间患者解剖区域的哪些区域将被电场覆盖。 此外，神经元模型可以应用于电场模型以产生激活场模型。 激活场模型指示哪个神经元将被解剖区域中的电场激活。 临床医生可以使用这些现场模型来确定在刺激递送之前的有效治疗。 特别地，当编程非轴对称或三维（3D））引线时，场模型可能是有益的，这些引导允许在创建刺激场方面具有更大的灵活性。
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10.发明授权Stimulation templates for programming a stimulation lead with complex electrode array geometry 有权用于用复杂电极阵列几何编程刺激引线的刺激模板公开(公告)号：US07676273B2
公开(公告)日：2010-03-09
申请号：US11591189
申请日：2006-10-31
IPC分类号： A61N1/00
CPC分类号： A61N1/37247 , A61N1/0529 , A61N1/0531 , A61N1/0534 , A61N1/0553 , A61N1/36082 , A61N1/36185
摘要： The disclosure is directed to programming implantable stimulators to deliver stimulation energy via one or more implantable leads having complex electrode array geometries. A user interface of a programmer allows a user to define stimulation therapy by interacting with one or more representations of the lead that delivers the therapy. The disclosure also contemplates selecting stimulation parameters to satisfy a user defined stimulation field by selecting one or more volumetric stimulation templates that best fit the stimulation field. The user interface may display the stimulation templates in relation to different perspectives of a lead and the stimulation field. Use of stimulation templates may simplify the determination of stimulation parameters in response to any of a variety of types of user definition of a stimulation field.
摘要翻译： 本公开涉及编程可植入刺激器以通过具有复杂电极阵列几何形状的一个或多个可植入引线输送刺激能量。 程序员的用户界面允许用户通过与递送治疗的引线的一个或多个表示相互作用来定义刺激治疗。 本公开还考虑通过选择最适合刺激场的一个或多个体积刺激模板来选择刺激参数以满足用户定义的刺激场。 用户界面可以显示与铅和刺激场的不同观点相关的刺激模板。 刺激模板的使用可以响应于刺激场的各种类型的用户定义中的任一种来简化刺激参数的确定。
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