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1.发明申请公开(公告)号：US20080206212A1
公开(公告)日：2008-08-28
申请号：US12035705
申请日：2008-02-22
CPC分类号： A61K31/202 , A61K35/745 , A61K35/747 , A61K2300/00
摘要： A novel method and product utilizing or containing one or more inactivated probiotics.
摘要翻译： 一种利用或含有一种或多种灭活益生菌的新方法和产品。
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公开(公告)号：US20080206213A1
公开(公告)日：2008-08-28
申请号：US12035718
申请日：2008-02-22
CPC分类号： A61K31/202 , A61K35/745 , A61K35/747 , A61K2300/00
摘要： The present invention is directed to a novel method for treating or preventing systemic inflammation in a subject. The method administering to the subject a therapeutically effective amount of inactivated LGG.
摘要翻译： 本发明涉及用于治疗或预防受试者全身炎症的新方法。 向受试者施用治疗有效量的灭活LGG的方法。
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3.发明授权公开(公告)号：US09408818B2
公开(公告)日：2016-08-09
申请号：US12035705
申请日：2008-02-22
IPC分类号： A61K31/202 , A61K35/745 , A61K35/747
CPC分类号： A61K31/202 , A61K35/745 , A61K35/747 , A61K2300/00
摘要： A children's or infant's nutritional product utilizing or containing one or more inactivated probiotics for preventing or reducing systemic and/or respiratory inflammation in a child or infant.
摘要翻译： 使用或含有一种或多种灭活益生菌以预防或减少儿童或婴儿的全身和/或呼吸道炎症的儿童或婴儿营养产品。
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公开(公告)号：US09408819B2
公开(公告)日：2016-08-09
申请号：US12035718
申请日：2008-02-22
IPC分类号： A61K31/202 , A61K35/745 , A61K35/747
CPC分类号： A61K31/202 , A61K35/745 , A61K35/747 , A61K2300/00
摘要： The present disclosure is directed to a novel nutritional formula for treating or preventing systemic inflammation in a subject. The nutritional formula comprises a therapeutically effective amount of inactivated Lactobacillus rhamnosus GG (LGG).
摘要翻译： 本公开涉及用于治疗或预防受试者的全身性炎症的新型营养配方。 营养配方包含治疗有效量的失活的鼠李糖乳杆菌GG（LGG）。
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5.发明申请公开(公告)号：US20110217402A1
公开(公告)日：2011-09-08
申请号：US12879136
申请日：2010-09-10
申请人： Eric A.F. van Tol , William Michael Russell , Udo Herz , Harald Renz , Holger Garn , Machtelt Braaksma , Maria Johanna van der Werf , Karin M. Overkamp
发明人： Eric A.F. van Tol , William Michael Russell , Udo Herz , Harald Renz , Holger Garn , Machtelt Braaksma , Maria Johanna van der Werf , Karin M. Overkamp
CPC分类号： C12N1/20 , A23L29/065 , A23L33/12 , A23L33/135 , A23L33/21 , A23L33/40 , A61K35/74 , C12N1/38 , A61K2300/00
摘要： A process for the preparation of a non-viable probiotic composition having anti-allergic (i.e. allergy preventive and/or anti-allergic in a therapeutic sense) properties, the process including the steps of (a) subjecting LGG to cultivation in a suitable culture medium using a batch process; (b) harvesting the culture supernatant at a late exponential phase of the cultivation step; (c) removing liquid contents from the culture supernatant so as to obtain the composition. Also, a composition comprising a proteinaceous mixture, said composition being obtainable by the above process, and the use thereof in a dietetic product preferably for targeting expecting mother's, infants, or children as well as application in food for specific medical purposes.
摘要翻译： 一种用于制备具有抗过敏（即治疗意义上的过敏预防和/或抗过敏）性质的不可行的益生菌组合物的方法，该方法包括以下步骤：（a）使LGG在合适的培养物中培养 培养基采用批处理; （b）在培养步骤的晚期指数期收获培养上清液; （c）从培养上清液中除去液体内容物，得到组合物。 此外，包含蛋白质混合物的组合物，所述组合物可通过上述方法获得，并且其在饮食产品中的用途优选用于期望母亲，婴儿或儿童的靶向以及用于特定医疗目的的食品中。
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公开(公告)号：US08075934B2
公开(公告)日：2011-12-13
申请号：US12371100
申请日：2009-02-13
申请人： Dattatreya Banavara , Win-Chin Chiang , Deborah A. Schade , Joaquin A. Franco , Juan M. Gonzalez , Dirk Hondmann , Zeina E. Jouni , Yung-Hsiung Lee , Robert J. McMahon , Kristin Morris , Deshanie Rai , Gyan P. Rai , Nagendra Rangavajla , Francisco J. Rosales , William Michael Russell , Eric Van Tol , Hugh N. Tucker , Donald Carey Walker
发明人： Dattatreya Banavara , Win-Chin Chiang , Deborah A. Schade , Joaquin A. Franco , Juan M. Gonzalez , Dirk Hondmann , Zeina E. Jouni , Yung-Hsiung Lee , Robert J. McMahon , Kristin Morris , Deshanie Rai , Gyan P. Rai , Nagendra Rangavajla , Francisco J. Rosales , William Michael Russell , Eric Van Tol , Hugh N. Tucker , Donald Carey Walker
IPC分类号： A23L1/30
CPC分类号： A23L33/12 , A23L33/16 , A23L33/17 , A23L33/40 , A23V2002/00 , A61K38/1841 , A61K2300/00 , A23V2250/1578 , A23V2200/3204 , A23V2250/1868 , A23V2200/3202 , A23V2250/18
摘要： The present invention is directed an improved nutritional composition, methods of improving digestion, and methods of enhancing the bioavailability of TGF-β.
摘要翻译： 本发明涉及改进的营养组合物，改善消化的方法以及提高TGF-β的生物利用度的方法。
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公开(公告)号：US20100104696A1
公开(公告)日：2010-04-29
申请号：US12371100
申请日：2009-02-13
申请人： Dattatreya Banavara , Win-Chin Chiang , Deborah A. Schade , Joaquin A. Franco , Juan M. Gonzalez , Dirk Hondmann , Zeina E. Jouni , Yung-Hsiung Lee , Robert J. McMahon , Kristin Morris , Deshanie Rai , Gyan P. Rai , Nagendra Rangavajla , Francisco J. Rosales , William Michael Russell , Eric Van Tol , Hugh N. Tucker , Donald Carey Walker
发明人： Dattatreya Banavara , Win-Chin Chiang , Deborah A. Schade , Joaquin A. Franco , Juan M. Gonzalez , Dirk Hondmann , Zeina E. Jouni , Yung-Hsiung Lee , Robert J. McMahon , Kristin Morris , Deshanie Rai , Gyan P. Rai , Nagendra Rangavajla , Francisco J. Rosales , William Michael Russell , Eric Van Tol , Hugh N. Tucker , Donald Carey Walker
CPC分类号： A23L33/12 , A23L33/16 , A23L33/17 , A23L33/40 , A23V2002/00 , A61K38/1841 , A61K2300/00 , A23V2250/1578 , A23V2200/3204 , A23V2250/1868 , A23V2200/3202 , A23V2250/18
摘要： The present invention is directed an improved nutritional composition, methods of improving digestion, and methods of enhancing the bioavailability of TGF-β.
摘要翻译： 本发明涉及改进的营养组合物，改善消化的方法以及提高TGF-β的生物利用度的方法。
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公开(公告)号：US20100074870A1
公开(公告)日：2010-03-25
申请号：US12284208
申请日：2008-09-19
CPC分类号： A61K35/745 , A23L33/135 , A23L33/40 , A23Y2300/55 , A61K31/202 , A61K31/702 , A61K45/06 , Y02A50/47 , Y02A50/473 , Y02A50/481 , A61K2300/00
摘要： The present invention is directed to an infant formula or children's nutritional product comprising a protein source, a fat source, a carbohydrate source, and B. longum AH1206.
摘要翻译： 本发明涉及包含蛋白质源，脂肪源，碳水化合物源和长双歧杆菌AH1206的婴儿配方食品或儿童营养产品。
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9.发明授权Polynucleotide encoding a Lactobacillus gasseri beta-glucuronidase polypeptide 失效编码加氏乳杆菌β-葡糖苷酸酶多肽的多核苷酸公开(公告)号：US06664097B2
公开(公告)日：2003-12-16
申请号：US09862660
申请日：2001-05-21
IPC分类号： C12N120
CPC分类号： C12Y302/01031 , C12N9/2434
摘要： The present invention provides isolated &bgr;-Glucuronidase (GUS) having activity at acidic pH and nucleic acids encoding the same. The nucleic acids may be isolated from any suitable species, and in a preferable embodiment are isolated from Lactobacillus gasseri.
摘要翻译： 本发明提供了在酸性pH下具有活性的分离的β-葡糖醛酸糖苷酶（GUS）和编码其的核酸。 核酸可以从任何合适的种类中分离出来，优选的实施方式是从加氏乳杆菌中分离出来的。
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公开(公告)号：US08137718B2
公开(公告)日：2012-03-20
申请号：US12284230
申请日：2008-09-19
CPC分类号： A61K31/702 , A23L33/135 , A23L33/21 , A23L33/40 , A61K35/745
摘要： The present invention is directed to an infant formula or children's nutritional product comprising a protein source, a fat source, a carbohydrate source, and B. longum AH1205.
摘要翻译： 本发明涉及包含蛋白质源，脂肪源，碳水化合物源和长双歧杆菌AH1205的婴儿配方食品或儿童营养产品。
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