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公开(公告)号：USRE35233E
公开(公告)日：1996-05-07
申请号：US180780
申请日：1994-01-10
IPC分类号： A61K31/195
CPC分类号： A61K31/195
摘要： The invention relates to a method of treating a catabolic dysfunction in an animal, which comprises administering to an animal a therapeutically effective amount of glutamine, or an analog thereof.
摘要翻译： 本发明涉及一种治疗动物分解代谢功能障碍的方法，其包括向动物施用治疗有效量的谷氨酰胺或其类似物。
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公开(公告)号：US5039704A
公开(公告)日：1991-08-13
申请号：US261649
申请日：1988-10-24
IPC分类号： A61K31/195
CPC分类号： A61K31/195
摘要： The invention relates to a method of treating a catabolic dysfunction in an animal, which comprises administering to an animal a therapeutically effective amount of glutamine, or an analog thereof.
摘要翻译： 本发明涉及一种治疗动物分解代谢功能障碍的方法，其包括向动物施用治疗有效量的谷氨酰胺或其类似物。
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公开(公告)号：US4857555A
公开(公告)日：1989-08-15
申请号：US906530
申请日：1986-09-12
IPC分类号： A61K31/195
CPC分类号： A61K31/195
摘要： The invention relates to a method of treating a catabolic dysfunction in an animal, which comprises administering to an animl a therapeutically effective amount of glutamine or an analog thereof.
摘要翻译： 本发明涉及一种治疗动物分解代谢功能障碍的方法，其包括给药一种治疗有效量的谷氨酰胺或其类似物。
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公开(公告)号：US20120070884A1
公开(公告)日：2012-03-22
申请号：US13232459
申请日：2011-09-14
IPC分类号： C12M1/40
CPC分类号： B01L7/5255 , B01L7/52 , B01L2200/147 , B01L2300/1822 , B01L2300/1827 , G01N35/0098 , G01N35/0099 , G01N2035/00356 , G01N2035/00524 , G01N2035/0437 , G01N2035/0455 , G01N2035/103 , Y10T436/11 , Y10T436/113332 , Y10T436/115831 , Y10T436/119163 , Y10T436/25 , Y10T436/2575
摘要： An automated analyzer for performing multiple diagnostic assays includes multiple modules in which aspects of the assay are performed on fluid samples contained in reaction receptacles. The analyzer includes stations for automatically preparing a sample, pre-heating the sample, incubating the sample, performing an analyte isolation procedure, and ascertaining the presence of a target analyte. A receptacle transporting system moves reaction receptacles from one station to the next. A method for performing an assay includes an automated process for isolating and amplifying a target analyte. The process is performed by moving each of a plurality of reaction receptacles containing a solid support material and a fluid sample between stations for pre-heating and incubating the contents of the reaction receptacle and for separating the target analyte bound to the solid support from the fluid sample. An amplification reagent is added to the analyte after the separation step and before incubation.
摘要翻译： 用于执行多个诊断测定的自动化分析仪包括多个模块，其中对反应容器中包含的流体样品进行测定的方面。 分析仪包括用于自动准备样品，预加热样品，孵育样品，进行分析物分离程序和确定目标分析物的存在的站。 插座运输系统将反应容器从一个站移动到另一个站。 用于进行测定的方法包括用于分离和扩增靶分析物的自动化方法。 该过程是通过在站之间移动包含固体支持材料和流体样品的多个反应容器中的每一个进行的，以预热和温育反应容器的内容物，并将与固体支持物结合的目标分析物与流体分离 样品。 在分离步骤之后和孵育前将扩增试剂加入到分析物中。
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公开(公告)号：US08137620B2
公开(公告)日：2012-03-20
申请号：US11869300
申请日：2007-10-09
IPC分类号： C12M1/36
CPC分类号： C12Q1/6834 , B01F9/0001 , B01F9/0014 , B01F9/0021 , B01F2009/0074 , B01L7/52 , B01L7/5255 , B01L9/06 , B01L2200/147 , B01L2300/1822 , B01L2300/1827 , B03C1/282 , B03C1/288 , B03C1/30 , B03C2201/26 , C12Q1/6813 , C12Q1/6832 , C12Q2537/10 , G01N35/0098 , G01N35/0099 , G01N35/025 , G01N35/1065 , G01N2035/00356 , G01N2035/00524 , G01N2035/0437 , G01N2035/0455 , G01N2035/103 , Y10T29/53657 , Y10T29/53683 , Y10T29/53843 , Y10T156/1105 , Y10T156/1906 , Y10T436/11 , Y10T436/111666 , Y10T436/113332 , Y10T436/114998 , Y10T436/119163 , Y10T436/2575
摘要： An automated analyzer for performing multiple diagnostic assays simultaneously includes multiple stations, or modules, in which discrete aspects of the assay are performed on fluid samples contained in reaction receptacles. The analyzer includes stations for automatically preparing a specimen sample, incubating the sample at prescribed temperatures for prescribed periods, performing an analyte isolation procedure, and ascertaining the presence of a target analyte. An automated receptacle transporting system moves the reaction receptacles from one station to the next. The analyzer further includes devices for carrying a plurality of specimen tubes and disposable pipette tips in a machine-accessible manner, a device for agitating containers of target capture reagents comprising suspensions of solid support material and for presenting the containers for machine access thereto, and a device for holding containers of reagents in a temperature controlled environment and presenting the containers for machine access thereto. A method for performing an automated diagnostic assay includes an automated process for isolating and amplifying a target analyte. The process is performed by automatically moving each of a plurality of reaction receptacles containing a solid support material and a fluid sample between stations for incubating the contents of the reaction receptacle and for separating the target analyte bound to the solid support from the fluid sample. An amplification reagent is added to the separated analyte after the analyte separation step and before a final incubation step.
摘要翻译： 用于执行多个诊断测定的自动分析仪同时包括多个站或模块，其中对反应容器中包含的流体样品进行分析方面的分析。 分析仪包括用于自动准备标本样品的台站，在规定温度下培养样品规定的时间，进行分析物分离程序，并确定目标分析物的存在。 自动插座输送系统将反应容器从一个站移动到另一个站。 分析仪还包括用于以机器可接近的方式携带多个样本管和一次性移液管尖端的装置，用于搅拌包含固体支持材料的悬浮液并用于提供用于机器通入的容器的靶捕获试剂的容器的装置，以及 用于在温度受控的环境中容纳试剂容器的装置，并且提供用于机器通入的容器。 执行自动诊断测定的方法包括用于分离和扩增靶分析物的自动化方法。 该过程通过在站之间自动移动包含固体支持材料和流体样品的多个反应容器中的每一个来进行，用于孵育反应容器的内容物并将与固体支持物结合的目标分析物与流体样品分离。 在分析物分离步骤之后和最终孵育步骤之前，将分离的分析物加入扩增试剂。
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公开(公告)号：US07910140B2
公开(公告)日：2011-03-22
申请号：US11559169
申请日：2006-11-13
CPC分类号： A61K36/185 , A01N65/00 , A01N65/08 , A23L3/3472 , A23L3/3481 , A23L3/3508 , A01N2300/00 , A01N25/02 , A01N31/02 , A01N61/00
摘要： The alkali metal salts form of β-acids dissolved in propylene glycol is used to control microbial growth in food products, process streams and other applications, including in cosmetic formulations.
摘要翻译： 用于溶解在丙二醇中的碱金属盐形式用于控制食品，工艺流和其它应用中的微生物生长，包括在化妆品制剂中。
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7.发明授权Automated process for detecting the presence of a target nucleic acid in a sample 有权用于检测样品中靶核酸的存在的自动化过程公开(公告)号：US07560256B2
公开(公告)日：2009-07-14
申请号：US11168374
申请日：2005-06-29
申请人： Kelly G. Ammann , Ralph E. Burns , Ernest V. Hansberry , Glenn A. Horner , Cheryl A. Jakub , John E. Kling , Donald J. Nieglos , Robert E. Schneider , Robert J. Smith
发明人： Kelly G. Ammann , Ralph E. Burns , Ernest V. Hansberry , Glenn A. Horner , Cheryl A. Jakub , John E. Kling , Donald J. Nieglos , Robert E. Schneider , Robert J. Smith
CPC分类号： C12Q1/6834 , B01F9/0001 , B01F9/0014 , B01F9/0021 , B01F2009/0074 , B01L7/52 , B01L7/5255 , B01L9/06 , B01L2200/147 , B01L2300/1822 , B01L2300/1827 , B03C1/282 , B03C1/288 , B03C1/30 , B03C2201/26 , C12Q1/6813 , C12Q1/6832 , C12Q2537/10 , G01N35/0098 , G01N35/0099 , G01N35/025 , G01N35/1065 , G01N2035/00356 , G01N2035/00524 , G01N2035/0437 , G01N2035/0455 , G01N2035/103 , Y10T29/53657 , Y10T29/53683 , Y10T29/53843 , Y10T156/1105 , Y10T156/1906 , Y10T436/11 , Y10T436/111666 , Y10T436/113332 , Y10T436/114998 , Y10T436/119163 , Y10T436/2575
摘要： An automated process for detecting the presence of a target nucleic acid in a sample. The process includes separating the target nucleic acid from other material present in the sample at a first station, transferring the separated target nucleic acid from the first station to a second station using a rotatable transport mechanism, combining the transferred target nucleic acid and reagents for performing an amplification reaction at the second station, and performing an amplification reaction. A product of the amplification reaction is detected as an indication of the presence of the target nucleic acid in the sample.
摘要翻译： 用于检测样品中靶核酸的存在的自动化过程。 该方法包括在第一站将目标核酸与样品中存在的其他物质分离，使用可转移的转运机制将分离的目标核酸从第一站转移到第二站，将转移的靶核酸和试剂结合，以进行 第二站的扩增反应，进行扩增反应。 检测扩增反应的产物作为样品中靶核酸的存在的指示。
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公开(公告)号：US20090095419A1
公开(公告)日：2009-04-16
申请号：US12335814
申请日：2008-12-16
申请人： Kelly G. Ammann , Ralph E. Burns , Ernest V. Hansberry , Glenn A. Horner , Cheryl A. Jakub , John E. Kling , Donald J. Nieglos , Robert E. Schneider , Robert J. Smith
发明人： Kelly G. Ammann , Ralph E. Burns , Ernest V. Hansberry , Glenn A. Horner , Cheryl A. Jakub , John E. Kling , Donald J. Nieglos , Robert E. Schneider , Robert J. Smith
IPC分类号： B29C63/00
CPC分类号： C12Q1/6834 , B01F9/0001 , B01F9/0014 , B01F9/0021 , B01F2009/0074 , B01L7/52 , B01L7/5255 , B01L9/06 , B01L2200/147 , B01L2300/1822 , B01L2300/1827 , B03C1/282 , B03C1/288 , B03C1/30 , B03C2201/26 , C12Q1/6813 , C12Q1/6832 , C12Q2537/10 , G01N35/0098 , G01N35/0099 , G01N35/025 , G01N35/1065 , G01N2035/00356 , G01N2035/00524 , G01N2035/0437 , G01N2035/0455 , G01N2035/103 , Y10T29/53657 , Y10T29/53683 , Y10T29/53843 , Y10T156/1105 , Y10T156/1906 , Y10T436/11 , Y10T436/111666 , Y10T436/113332 , Y10T436/114998 , Y10T436/119163 , Y10T436/2575
摘要： An automated analyzer for performing multiple diagnostic assays simultaneously includes multiple stations, or modules, in which discrete aspects of the assay are performed on fluid samples contained in reaction receptacles. The analyzer includes stations for automatically preparing a specimen sample, incubating the sample at prescribed temperatures for prescribed periods, performing an analyte isolation procedure, and ascertaining the presence of a target analyte. An automated receptacle transporting system moves the reaction receptacles from one station to the next. The analyzer further includes devices for carrying a plurality of specimen tubes and disposable pipette tips in a machine-accessible manner, a device for agitating containers of target capture reagents comprising suspensions of solid support material and for presenting the containers for machine access thereto, and a device for holding containers of reagents in a temperature controlled environment and presenting the containers for machine access thereto. A method for performing an automated diagnostic assay includes an automated process for isolating and amplifying a target analyte. The process is performed by automatically moving each of a plurality of reaction receptacles containing a solid support material and a fluid sample between stations for incubating the contents of the reaction receptacle and for separating the target analyte bound to the solid support from the fluid sample. An amplification reagent is added to the separated analyte after the analyte separation step and before a final incubation step.
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9.发明申请公开(公告)号：US20090067280A1
公开(公告)日：2009-03-12
申请号：US11875306
申请日：2007-10-19
IPC分类号： B01F15/06
CPC分类号： C12Q1/6834 , B01F9/0001 , B01F9/0014 , B01F9/0021 , B01F2009/0074 , B01L7/52 , B01L7/5255 , B01L9/06 , B01L2200/147 , B01L2300/1822 , B01L2300/1827 , B03C1/282 , B03C1/288 , B03C1/30 , B03C2201/26 , C12Q1/6813 , C12Q1/6832 , C12Q2537/10 , G01N35/0098 , G01N35/0099 , G01N35/025 , G01N35/1065 , G01N2035/00356 , G01N2035/00524 , G01N2035/0437 , G01N2035/0455 , G01N2035/103 , Y10T29/53657 , Y10T29/53683 , Y10T29/53843 , Y10T156/1105 , Y10T156/1906 , Y10T436/11 , Y10T436/111666 , Y10T436/113332 , Y10T436/114998 , Y10T436/119163 , Y10T436/2575
摘要： An automated analyzer for performing multiple diagnostic assays simultaneously includes multiple stations, or modules, in which discrete aspects of the assay are performed on fluid samples contained in reaction receptacles. The analyzer includes stations for automatically preparing a specimen sample, incubating the sample at prescribed temperatures for prescribed periods, performing an analyte isolation procedure, and ascertaining the presence of a target analyte. An automated receptacle transporting system moves the reaction receptacles from one station to the next. The analyzer further includes devices for carrying a plurality of specimen tubes and disposable pipette tips in a machine-accessible manner, a device for agitating containers of target capture reagents comprising suspensions of solid support material and for presenting the containers for machine access thereto, and a device for holding containers of reagents in a temperature controlled environment and presenting the containers for machine access thereto. A method for performing an automated diagnostic assay includes an automated process for isolating and amplifying a target analyte. The process is performed by automatically moving each of a plurality of reaction receptacles containing a solid support material and a fluid sample between stations for incubating the contents of the reaction receptacle and for separating the target analyte bound to the solid support from the fluid sample. An amplification reagent is added to the separated analyte after the analyte separation step and before a final incubation step.
摘要翻译： 用于执行多个诊断测定的自动分析仪同时包括多个站或模块，其中对反应容器中包含的流体样品进行分析方面的分析。 分析仪包括用于自动准备标本样品，在规定温度下规定时间孵育样品，进行分析物分离程序，以及确定目标分析物的存在的站。 自动插座输送系统将反应容器从一个站移动到另一个站。 分析仪还包括用于以机器可接近的方式携带多个样本管和一次性移液管尖端的装置，用于搅拌包含固体支持材料的悬浮液并用于提供用于机器通入的容器的靶捕获试剂的容器的装置，以及 用于在温度受控的环境中容纳试剂容器的装置，并且提供用于机器通入的容器。 执行自动诊断测定的方法包括用于分离和扩增靶分析物的自动化方法。 该过程通过在站之间自动移动包含固体支持材料和流体样品的多个反应容器中的每一个来进行，用于孵育反应容器的内容物并将与固体支持物结合的目标分析物与流体样品分离。 在分析物分离步骤之后和最终孵育步骤之前，将分离的分析物加入扩增试剂。
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公开(公告)号：US07475199B1
公开(公告)日：2009-01-06
申请号：US09694071
申请日：2000-10-19
申请人： Jared E. Bobbitt , Jiong (Justin) Chen , Stephan A. Doll , John W. Fawcett , Marc T. Friedman , Robert C. Hickman , Edward P. Johnson , Ty Lam , Patrick Wing Sang Lau , Joseph P. Mullally , Robert J. Smith , Jeffrey C. Tanner
发明人： Jared E. Bobbitt , Jiong (Justin) Chen , Stephan A. Doll , John W. Fawcett , Marc T. Friedman , Robert C. Hickman , Edward P. Johnson , Ty Lam , Patrick Wing Sang Lau , Joseph P. Mullally , Robert J. Smith , Jeffrey C. Tanner
IPC分类号： G06F12/00
CPC分类号： G06F17/30233 , G06F3/0607 , G06F3/0647 , G06F3/0665 , G06F3/067 , G06F17/30079 , G06F17/30194 , Y10S707/99953 , Y10S707/99955
摘要： An incrementally-scalable file system and method. The system architecture enables file systems to be scaled by adding resources, such as additional filers and/or file servers, without requiring that the system be taken offline or being known to client applications. The system also provides for load balancing file accesses by distributing files across the various file storage resources in the system, as dictated by the relative capacities of said storage resources. The system provides one or more “virtual” file system volumes in a manner that makes it appear to client applications that all of the file system's storage space resides on the virtual volume(s), while in reality the files may be stored on many more physical volumes on the filers and/or file servers in the system.
摘要翻译： 一种递增可扩展的文件系统和方法。 系统架构可以通过添加资源（如附加的文件管理器和/或文件服务器）来扩展文件系统，而不需要将系统脱机或被客户端应用程序所知。 该系统还通过根据所述存储资源的相对容量来指定跨系统中的各种文件存储资源分发文件来提供负载平衡文件访问。 系统提供一个或多个“虚拟”文件系统卷，以使客户端应用程序看到所有文件系统的存储空间驻留在虚拟卷上，而实际上文件可能存储在更多的文件系统上 系统中文件管理器和/或文件服务器上的物理卷。
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