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公开(公告)号：US20110022129A1
公开(公告)日：2011-01-27
申请号：US12741334
申请日：2008-11-05
CPC分类号： A61K9/0009
摘要： Embodiments of the invention include nanoparticulate products of a flash nanoprecipitation process, the products comprising, in combination, pre-formed nanoparticles having properties of an upconversion phosphor and a hydrophobic organic compound having the properties of a photosensitizer, and a method of photodynamic therapy comprising the use of the nanoparticulate products is described.
摘要翻译： 本发明的实施方案包括快速纳米颗粒沉积方法的纳米颗粒产物，该组合物包含具有上转换荧光体和具有光敏剂性质的疏水性有机化合物的特性的预形成纳米颗粒，以及包含 描述了纳米颗粒产品的使用。
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公开(公告)号：US09943490B2
公开(公告)日：2018-04-17
申请号：US12265206
申请日：2008-11-05
申请人： Robert K. Prud'homme , Marian Gindy , Ying Liu
发明人： Robert K. Prud'homme , Marian Gindy , Ying Liu
CPC分类号： A61K9/5153 , A61K49/0019 , A61K49/0065 , A61K49/0093 , A61K49/1857 , Y10T428/2991
摘要： The invention described herein relates to sterically stabilized colloidal constructs comprising preformed colloidal particles encapsulated within a polymeric shell. The constructs, which are controllably sized, are nanoparticles comprising hydrophobic elements, electrostatically charged particles with hydrophobic surfaces, hydrophobic inorganic nanostructures, and amphiphilic copolymers with hydrophobic domains and hydrophilic domains. The constructs are made by a process that allows for the simultaneous encapsulation of a preformed colloidal agent as well as a dissolved hydrophobic active within the core of the polymeric nanoparticle. Among the actives incorporated in various embodiments are organic fluorescent dyes, metal nanostructures and superparamagnetic materials for use in combined fluorescence, optical and magnetic resonance imaging applications, and hydrophobic drugs for therapeutic applications.
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公开(公告)号：US20100330368A1
公开(公告)日：2010-12-30
申请号：US12265206
申请日：2008-11-05
申请人： Robert K. Prud'homme , Marian Gindy , Ying Liu
发明人： Robert K. Prud'homme , Marian Gindy , Ying Liu
IPC分类号： B32B15/04
CPC分类号： A61K9/5153 , A61K49/0019 , A61K49/0065 , A61K49/0093 , A61K49/1857 , Y10T428/2991
摘要： The invention described herein relates to sterically stabilized colloidal constructs comprising preformed colloidal particles encapsulated within a polymeric shell. The constructs, which are controllably sized, are nanoparticles comprising hydrophobic elements, electrostatically charged particles with hydrophobic surfaces, hydrophobic inorganic nanostructures, and amphiphilic copolymers with hydrophobic domains and hydrophilic domains. The constructs are made by a process that allows for the simultaneous encapsulation of a preformed colloidal agent as well as a dissolved hydrophobic active within the core of the polymeric nanoparticle. Among the actives incorporated in various embodiments are organic fluorescent dyes, metal nanostructures and superparamagnetic materials for use in combined fluorescence, optical and magnetic resonance imaging applications, and hydrophobic drugs for therapeutic applications.
摘要翻译： 本文描述的本发明涉及包含预先形成的包封在聚合物壳内的胶体颗粒的空间稳定的胶体构造物。 可控制尺寸的构造体是包含疏水性元素的纳米颗粒，具有疏水表面的带静电荷的颗粒，疏水性无机纳米结构和具有疏水域和亲水结构域的两亲共聚物。 构建体通过允许预先形成的胶体剂以及在聚合物纳米颗粒的核心内的溶解的疏水性活性物质同时包封的方法制备。 在各种实施方案中引入的活性物质是用于组合荧光，光学和磁共振成像应用的有机荧光染料，金属纳米结构和超顺磁性材料，以及用于治疗应用的疏水性药物。
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公开(公告)号：US11246568B2
公开(公告)日：2022-02-15
申请号：US16393976
申请日：2019-04-25
申请人： Ying Liu
发明人： Ying Liu
IPC分类号： B06B1/06 , H01L41/04 , A61B8/00 , A61B8/14 , B06B1/02 , B06B3/00 , G10K11/34 , G01S15/89 , H01H89/00 , H01G2/00 , H01G9/28 , H01L41/113
摘要： A circuit for 3D ultrasound imaging systems includes multiple sensor units, multiple unit circuits and multiple row sharing circuits. The unit circuits are connected with the sensor units respectively. Each row of unit circuits share a row sharing circuit. Each unit circuit includes a first electrically controlled switch, a second electrically controlled switch and a control circuit. Each row sharing circuit includes a signal transmission bus, a signal receiving bus and a row main control circuit. The signal transmission bus and the signal receiving bus of each row sharing circuit extend through a corresponding row of unit circuits. The row main control circuit of each row is configured to transmit main control signals, transmission control signals and receiving control signals to a corresponding row of unit circuits so as to select the corresponding sensor units to transmit or receive ultrasound signals.
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公开(公告)号：US09957564B2
公开(公告)日：2018-05-01
申请号：US13807660
申请日：2011-06-30
申请人： Jian Li , Shiping Chen , Xiandong Zhang , Ying Liu , Caifen Zhang , Tao Liu , Meiru Zhao
发明人： Jian Li , Shiping Chen , Xiandong Zhang , Ying Liu , Caifen Zhang , Tao Liu , Meiru Zhao
IPC分类号： C12Q1/68
CPC分类号： C12Q1/6881 , C12Q1/6844 , C12Q1/6869 , C12Q2600/156 , C12Q2600/16 , C12Q2600/172 , C12Q2525/191
摘要： The invention provides a PCR sequencing method, wherein the combination of primer indexes, DNA incomplete shearing strategy and the second generation sequencing technique (Paired-End sequencing technique) can make the length of PCR products that can be sequenced by a sequencer longer than the maximum sequencing length of the sequencer while making full use of the characteristics of the second generation sequencing technique such as high throughput and low cost, thereby greatly broadening its applicable scope. In addition, the present invention also provides primer indexes for the PCR sequencing method and the use of the method in genotyping, particularly in HLA analysis, and also provides the PCR primers used, particularly the PCR primers for HLA-A, B, HLA-C and HLA-DQB1 gene.
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公开(公告)号：US09057801B2
公开(公告)日：2015-06-16
申请号：US13347775
申请日：2012-01-11
申请人： John Jiang , Azizuddin Abdul Aziz , Ying Liu , Kurt-M. Strack
发明人： John Jiang , Azizuddin Abdul Aziz , Ying Liu , Kurt-M. Strack
摘要： A geophysical data acquisition system includes at least one geophysical sensor. The at least one geophysical sensor has associated therewith a signal generator configured to generate a signal corresponding to a type of the at least one geophysical sensor. The system includes at least one signal acquisition unit having a plurality of input channels. The at least one geophysical sensor is in signal communication with one of the plurality of input channels. The plurality of input channels each includes a detector for receiving and identifying the signal generated by the signal generator. The at least one signal acquisition unit includes amplification, filtering and digitizing circuits automatically configurable in response to the type of sensor identified by the detected signal.
摘要翻译： 地球物理数据采集系统包括至少一个地球物理传感器。 所述至少一个地球物理传感器具有与其相关联的信号发生器，其被配置为产生对应于所述至少一个地球物理传感器的类型的信号。 该系统包括具有多个输入通道的至少一个信号获取单元。 所述至少一个地球物理传感器与所述多个输入通道之一进行信号通信。 多个输入通道各自包括用于接收和识别由信号发生器产生的信号的检测器。 所述至少一个信号获取单元包括响应于由检测到的信号识别的传感器的类型而自动配置的放大，滤波和数字化电路。
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公开(公告)号：US09030470B2
公开(公告)日：2015-05-12
申请号：US13585807
申请日：2012-08-14
CPC分类号： G01B11/2509
摘要： The present invention discloses a non-contact measurement system for measuring the three-dimensional (3D) shape of an object rapidly by using a unique light pattern and the implementation method thereof. The system comprises a pattern generation unit, a projection unit, a sensing unit and a processing unit. The pattern generation unit generates an enhanced color sequence according to predetermined rules. The sensing unit of the system comprises a hybrid sensor which can be operated in fast mode or precise mode. A dedicated decoding method for the present invention is also disclosed.
摘要翻译： 本发明公开了一种通过使用独特的光图案快速测量物体的三维（3D）形状的非接触测量系统及其实现方法。 该系统包括图案生成单元，投影单元，感测单元和处理单元。 图案生成单元根据预定的规则生成增强的颜色序列。 该系统的感测单元包括可以在快速模式或精确模式下操作的混合传感器。 还公开了本发明的专用解码方法。
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公开(公告)号：US08977253B2
公开(公告)日：2015-03-10
申请号：US13143198
申请日：2009-12-24
申请人： Kun Liu , Zhaohua Lu , Ying Liu , Feng Xie , Yang Liu , Hongyun Qu
发明人： Kun Liu , Zhaohua Lu , Ying Liu , Feng Xie , Yang Liu , Hongyun Qu
摘要： The present invention discloses a method for sending auxiliary detection signaling, comprising: for each base station in a base station group, that is, a first base station, the other base stations in the base station group except the first base station respectively send auxiliary detection signaling at the carrier frequency of the first base station. The technical solution saves both signaling overhead and power and reduces the complexity of a search carried out by an MS.
摘要翻译： 本发明公开了一种发送辅助检测信令的方法，包括：对于基站组中的每个基站，即第一基站，基站组除第一基站之外的其他基站分别发送辅助检测 在第一基站的载波频率处的信令。 技术解决方案节省了信令开销和功率，并降低了MS进行的搜索的复杂性。
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公开(公告)号：US08962880B2
公开(公告)日：2015-02-24
申请号：US14006198
申请日：2012-03-21
申请人： Guobin Ren , Ying Liu , Jinyao Chen , Xiaoling Huang , Lin Xiao , Li Cai , Zhen Zhang , Xuejun Wu , Haiyan Sun , Quanhai Liu , Liling Jin , Minyu Liu , Yifang Deng , Zhiru Xu , Renhai Chen , Chungang Li , Xiangduan Tan , Yan Qin
发明人： Guobin Ren , Ying Liu , Jinyao Chen , Xiaoling Huang , Lin Xiao , Li Cai , Zhen Zhang , Xuejun Wu , Haiyan Sun , Quanhai Liu , Liling Jin , Minyu Liu , Yifang Deng , Zhiru Xu , Renhai Chen , Chungang Li , Xiangduan Tan , Yan Qin
IPC分类号： C07C227/14 , C07C215/10 , C07C229/38 , C07J63/00
CPC分类号： C07C227/14 , C07C215/10 , C07C229/38 , C07J63/008
摘要： An amorphous asiatic tromethamine salt and the preparation method thereof. The method includes the steps of: (1) dissolving asiatic acid in an organic solvent; step (2) mixing with tromethamine; step (3) stirring and salifying the same, and then removing the organic solvent. The method for preparing the amorphous asiatic tromethamine salt is easy and effective, and the water solubility and bioavailability of the asiatic tromethamine salt thus obtained are greatly compared with the prior art.
摘要翻译： 一种无定形亚洲氨丁三醇盐及其制备方法。 该方法包括以下步骤：（1）将积雪草酸溶解在有机溶剂中; 步骤（2）与氨丁三醇混合; 步骤（3）搅拌并使其成盐，然后除去有机溶剂。 无定形亚洲氨基丁三醇盐的制备方法容易有效，与现有技术相比，所得到的亚稳氨基甲基胺盐的水溶性和生物利用度大大降低。
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