摘要:
The present invention is based on the discovery of a set of genes that are involved in lipid-droplet formation and regulation. Accordingly, the present invention provides methods of increasing or decreasing lipid concentrations in eukaryotic cells by decreasing or increasing expression of one of these genes. Increased lipid concentrations may be useful, for example, in the generation of biofuels. Decreased lipid concentration may be useful in the treatment of diseases characterized by excessive lipid storage. In addition, the invention provides methods of identifying markers of diseases characterized by excessive lipid storage.
摘要:
The present invention is based on the discovery of a set of genes that are involved in lipid-droplet formation and regulation. Accordingly, the present invention provides methods of increasing or decreasing lipid concentrations in eukaryotic cells by decreasing or increasing expression of one of these genes. Increased lipid concentrations may be useful, for example, in the generation of biofuels. Decreased lipid concentration may be useful in the treatment of diseases characterized by excessive lipid storage. In addition, the invention provides methods of identifying markers of diseases characterized by excessive lipid storage.
摘要:
Disclosed herein are, inter alia, compositions for modulating Ire1, Src, or Abl, methods for identifying modulating activity in test compounds, and methods for treating diseases caused by the activity or inactivity of Ire1, Src, or Abl.
摘要:
A process for the preparation of pressure sensitive adhesive tapes where cationic cure is conducted against liners and substrates with low moisture content and in an environment where moisture ingress during cure is prevented.
摘要:
The invention relates to a lining for columns of automobiles comprising a base area (1) with fixing and holding elements (4) and at least one opening area (2) covering, for example, an airbag (3). According to the invention, the opening area (2) consists largely of a thermoplastic material with a Shore A hardness of more than 100 and has a hinge area (6) consisting of a thermopolastic material with a Shore A hardness of less than 95, which adjoins the base area (1).
摘要:
The application relates to a unitary case for a plurality of angular drives which comprises at least one bevel gear step with a first bevel gear and a second bevel gear, and which is provided for achieving various angles between a transmission input shaft and a transmission output shaft. The second bevel gear is coupled to the transmission output shaft in an indirect rotationally fixed manner. The unitary case is designed for a plurality of possible angular outputs wherein multiplication is substantially constant and the outer diameters of the individual bevel gears are substantially identical.
摘要:
A filling assembly for an aseptically operating deep-drawing packing machine, wherein a conveying region for the web of packing sheet is provided within a pipe held in sterile condition. Arranged behind a packing sheet-forming station is a filling station comprising at least one loading tube stationary with respect to the conveying region yet displaceable in a direction vertical to the conveying region. In order to enable the packing machine to continue to run also during cleaning of the filling station, two filling stations are arranged in series on the pipe maintained in sterile condition within openings displaceable on the sterile pipe above the conveying region. Only one of the said filling stations is respectively in the operating position while the other of said filling stations is in the cleaning position. The filling stations in view of their displaceable openings on the sterile pipe are reciprocable between an operating position and a cleaning position. For this purpose, the filling assemblies are comprised of a tank part accommodating the loading tube in the cleaning position, and of a loading tube-passage part.
摘要:
The invention relates to a labeling device (10) for a thermoforming system (100) comprising: a supply device (11) for at least one label reel (12) having a plurality of labels (1); a first cutting device (26) for separating each label (1) from the at least one label reel (12); a preferably drum-like transfer device (45) for transferring each label (1) separated from the at least one label reel (12) to a mold (102, 103) of a molding tool (101) for producing a container (80), wherein the molding tool (101) comprises several molds (102, 103), and wherein all containers (80) can be produced in the respective molds (102, 103) in one manufacturing cycle by the molding tool (101). According to the invention, the first cutting device (26) is assigned to multiple molds (102, 103) of the molding tool (101) and a label feed device (35) is provided, said device feeding each label (1) separated from the at least one label reel (12) by the cutting device (26) to the transfer devices (45) of the molds (102, 103).
摘要:
The invention relates to a labeling device (10) for a thermoforming system (100) comprising: a supply device (11) for at least one label reel (12) having a plurality of labels (1); a first cutting device (26) for separating each label (1) from the at least one label reel (12); a preferably drum-like transfer device (45) for transferring each label (1) separated from the at least one label reel (12) to a mold (102, 103) of a molding tool (101) for producing a container (80), wherein the molding tool (101) comprises several molds (102, 103), and wherein all containers (80) can be produced in the respective molds (102, 103) in one manufacturing cycle by the molding tool (101). According to the invention, the first cutting device (26) is assigned to multiple molds (102, 103) of the molding tool (101) and a label feed device (35) is provided, said device feeding each label (1) separated from the at least one label reel (12) by the cutting device (26) to the transfer devices (45) of the molds (102, 103).