Methods of modulating lipid concentrations in eukaryotic cells
    1.
    发明授权
    Methods of modulating lipid concentrations in eukaryotic cells 有权
    调节真核细胞中脂质浓度的方法

    公开(公告)号:US08435790B2

    公开(公告)日:2013-05-07

    申请号:US12508853

    申请日:2009-07-24

    IPC分类号: C12N15/01

    摘要: The present invention is based on the discovery of a set of genes that are involved in lipid-droplet formation and regulation. Accordingly, the present invention provides methods of increasing or decreasing lipid concentrations in eukaryotic cells by decreasing or increasing expression of one of these genes. Increased lipid concentrations may be useful, for example, in the generation of biofuels. Decreased lipid concentration may be useful in the treatment of diseases characterized by excessive lipid storage. In addition, the invention provides methods of identifying markers of diseases characterized by excessive lipid storage.

    摘要翻译: 本发明基于一组参与脂滴形成和调节的基因的发现。 因此,本发明提供通过减少或增加这些基因之一的表达来增加或减少真核细胞中的脂质浓度的方法。 增加的脂质浓度可能是有用的,例如生物燃料的产生。 降低的脂质浓度可用于治疗以过量脂质储存为特征的疾病。 此外,本发明提供鉴定以过量脂质储存为特征的疾病的标志物的方法。

    Lining for columns of automobiles
    5.
    发明授权
    Lining for columns of automobiles 失效
    衬里为汽车柱

    公开(公告)号:US06874809B1

    公开(公告)日:2005-04-05

    申请号:US09979541

    申请日:2000-05-05

    摘要: The invention relates to a lining for columns of automobiles comprising a base area (1) with fixing and holding elements (4) and at least one opening area (2) covering, for example, an airbag (3). According to the invention, the opening area (2) consists largely of a thermoplastic material with a Shore A hardness of more than 100 and has a hinge area (6) consisting of a thermopolastic material with a Shore A hardness of less than 95, which adjoins the base area (1).

    摘要翻译: 本发明涉及一种用于汽车柱的衬里,其包括具有固定和保持元件(4)的基部区域(1)和覆盖例如气囊(3)的至少一个开口区域(2)。 根据本发明,开口区域(2)主要由肖氏A硬度大于100的热塑性材料构成,并且具有由肖氏A硬度小于95的热弹性材料构成的铰链区域(6),其中 毗邻基地区(1)。

    Filling assembly for aseptically operating deep-drawing packing machines
    7.
    发明授权
    Filling assembly for aseptically operating deep-drawing packing machines 失效
    无菌操作深冲包装机的灌装装置

    公开(公告)号:US06179017B2

    公开(公告)日:2001-01-30

    申请号:US09491648

    申请日:2000-01-27

    申请人: Peter Walter

    发明人: Peter Walter

    IPC分类号: B65B104

    摘要: A filling assembly for an aseptically operating deep-drawing packing machine, wherein a conveying region for the web of packing sheet is provided within a pipe held in sterile condition. Arranged behind a packing sheet-forming station is a filling station comprising at least one loading tube stationary with respect to the conveying region yet displaceable in a direction vertical to the conveying region. In order to enable the packing machine to continue to run also during cleaning of the filling station, two filling stations are arranged in series on the pipe maintained in sterile condition within openings displaceable on the sterile pipe above the conveying region. Only one of the said filling stations is respectively in the operating position while the other of said filling stations is in the cleaning position. The filling stations in view of their displaceable openings on the sterile pipe are reciprocable between an operating position and a cleaning position. For this purpose, the filling assemblies are comprised of a tank part accommodating the loading tube in the cleaning position, and of a loading tube-passage part.

    摘要翻译: 一种用于无菌操作的深冲包装机的填充组件,其中包装片材的输送区域设置在保持无菌状态的管道内。 安装在包装片形成站后面的是一个填充站,该填充站包括相对于输送区静止的至少一个装载管,并且可沿垂直于输送区的方向移位。 为了使包装机能够在清洁加油站期间继续运行,两个加油站串联布置在保持无菌状态的管道上,可在可移动到输送区域上方的无菌管上的开口内。 所述加油站中只有一个分别处于操作位置,而另一个加油站处于清洁位置。 鉴于其在无菌管上的可移动开口的加油站在操作位置和清洁位置之间是往复运动的。 为此,填充组件包括容纳处于清洁位置的装载管的容器部分和装载管通道部分。

    Labeling device for a thermoforming system and method
    8.
    发明授权
    Labeling device for a thermoforming system and method 有权
    热成型系统和方法的标签装置

    公开(公告)号:US09481123B2

    公开(公告)日:2016-11-01

    申请号:US14345819

    申请日:2012-07-25

    IPC分类号: B29C51/16 B29C49/24

    摘要: The invention relates to a labeling device (10) for a thermoforming system (100) comprising: a supply device (11) for at least one label reel (12) having a plurality of labels (1); a first cutting device (26) for separating each label (1) from the at least one label reel (12); a preferably drum-like transfer device (45) for transferring each label (1) separated from the at least one label reel (12) to a mold (102, 103) of a molding tool (101) for producing a container (80), wherein the molding tool (101) comprises several molds (102, 103), and wherein all containers (80) can be produced in the respective molds (102, 103) in one manufacturing cycle by the molding tool (101). According to the invention, the first cutting device (26) is assigned to multiple molds (102, 103) of the molding tool (101) and a label feed device (35) is provided, said device feeding each label (1) separated from the at least one label reel (12) by the cutting device (26) to the transfer devices (45) of the molds (102, 103).

    摘要翻译: 本发明涉及一种用于热成型系统(100)的标签装置(10),包括:用于至少一个具有多个标签(1)的标签卷轴(12)的供应装置(11) 用于将每个标签(1)与所述至少一个标签卷轴(12)分离的第一切割装置(26); 用于将从至少一个标签卷轴(12)分离的每个标签(1)转移到用于制造容器(80)的模制工具(101)的模具(102,103)中的优选滚筒状转印装置(45) ,其中所述模制工具(101)包括多个模具(102,103),并且其中所有容器(80)可以通过所述模制工具(101)在一个制造周期中在相应的模具(102,103)中制造。 根据本发明,第一切割装置(26)被分配给模具(101)的多个模具(102,103),并且设置有标签馈送装置(35),所述装置将每个标签(1)与 所述至少一个标签卷轴(12)由所述切割装置(26)连接到所述模具(102,103)的所述传送装置(45)。

    LABELING DEVICE FOR A THERMOFORMING SYSTEM AND METHOD
    9.
    发明申请
    LABELING DEVICE FOR A THERMOFORMING SYSTEM AND METHOD 有权
    用于热成型系统和方法的标签装置

    公开(公告)号:US20140224428A1

    公开(公告)日:2014-08-14

    申请号:US14345819

    申请日:2012-07-25

    IPC分类号: B29C51/16

    摘要: The invention relates to a labeling device (10) for a thermoforming system (100) comprising: a supply device (11) for at least one label reel (12) having a plurality of labels (1); a first cutting device (26) for separating each label (1) from the at least one label reel (12); a preferably drum-like transfer device (45) for transferring each label (1) separated from the at least one label reel (12) to a mold (102, 103) of a molding tool (101) for producing a container (80), wherein the molding tool (101) comprises several molds (102, 103), and wherein all containers (80) can be produced in the respective molds (102, 103) in one manufacturing cycle by the molding tool (101). According to the invention, the first cutting device (26) is assigned to multiple molds (102, 103) of the molding tool (101) and a label feed device (35) is provided, said device feeding each label (1) separated from the at least one label reel (12) by the cutting device (26) to the transfer devices (45) of the molds (102, 103).

    摘要翻译: 本发明涉及一种用于热成型系统(100)的标签装置(10),包括:用于至少一个具有多个标签(1)的标签卷轴(12)的供应装置(11) 用于将每个标签(1)与所述至少一个标签卷轴(12)分离的第一切割装置(26); 用于将从至少一个标签卷轴(12)分离的每个标签(1)转移到用于制造容器(80)的模制工具(101)的模具(102,103)中的优选滚筒状转印装置(45) ,其中所述模制工具(101)包括多个模具(102,103),并且其中所有容器(80)可以通过所述模制工具(101)在一个制造周期中在相应的模具(102,103)中制造。 根据本发明,第一切割装置(26)被分配给模具(101)的多个模具(102,103),并且设置有标签馈送装置(35),所述装置将每个标签(1)与 所述至少一个标签卷轴(12)由所述切割装置(26)连接到所述模具(102,103)的所述传送装置(45)。