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    Methods and systems for in situ tissue marking and orientation stabilization
    1.
    发明申请
    Methods and systems for in situ tissue marking and orientation stabilization 审中-公开
    用于原位组织标记和取向稳定的方法和系统

    公开(公告)号：US20070198010A1

    公开(公告)日：2007-08-23

    申请号：US11737382

    申请日：2007-04-19

    申请人： Roberta LEE ,  James Vetter ,  Ary Chernomorsky

    发明人： Roberta LEE ,  James Vetter ,  Ary Chernomorsky

    IPC分类号： A61B18/00 ,  A61B10/00

    CPC分类号： A61B10/0266 ,  A61B18/148 ,  A61B2018/00333 ,  A61B2018/00601 ,  A61B2018/141 ,  A61B2018/1475 ,  A61B2090/3908 ,  A61B2090/3937 ,  A61B2090/395

    摘要： A method of marking an orientation of a cut specimen of tissue prior to excision thereof from a body includes steps of disposing a tissue-marking probe in the body adjacent the cut specimen, the tissue-marking probe including a tissue-marking tool configured to selectively mark the cut specimen. A surface of the cut specimen is then marked with the tissue-marking tool such that the orientation of the cut specimen within the body is discernable after the cut specimen is excised from the body. The tissue-marking tool may be configured to selectively bow out of and back into a window defined near a distal tip of the probe and the marking step may include a step of selectively bowing the tissue-marking tool out of the window and following the surface of the cut specimen while rotating the probe. The tissue-marking tool may include an RF cutting tool and the marking step may include a step of coagulating or cauterizing a selected portion of the surface of the cut specimen with the RF cutting tool. Alternatively, the marking step may include a step of delivering dye onto selected portions of the surface of the cut specimen.

    摘要翻译： 在从身体切除之前标记组织切割样本的取向的方法包括以下步骤：将组织标记探针设置在与切割的样本相邻的身体中，组织标记探针包括组织标记工具，其被配置为选择性地 标记切割标本。 然后用组织标记工具标记切割的样品的表面，使得在切割的样品从身体切除之后，切割的样品在体内的取向是可辨别的。 组织标记工具可以被配置为选择性地弯曲到限定在探针的远侧末端附近的窗口中，并且标记步骤可以包括将组织标记工具选择性地弯曲出窗户并且跟随表面的步骤 同时旋转探头。 组织标记工具可以包括RF切割工具，并且标记步骤可以包括用RF切割工具凝固或烧灼切割样品表面的选定部分的步骤。 或者，标记步骤可以包括将染料递送到切割样品的表面的选定部分上的步骤。

    Methods and systems for in situ tissue marking and orientation stabilization
    3.
    发明申请
    Methods and systems for in situ tissue marking and orientation stabilization 失效
    用于原位组织标记和取向稳定的方法和系统

    公开(公告)号：US20050027291A1

    公开(公告)日：2005-02-03

    申请号：US10871790

    申请日：2004-06-17

    申请人： Roberta Lee ,  James Vetter ,  Ary Chernomorsky

    发明人： Roberta Lee ,  James Vetter ,  Ary Chernomorsky

    IPC分类号： A61B10/02 ,  A61B18/14 ,  A61B19/00 ,  A61B18/18 ,  A61B10/00

    CPC分类号： A61B10/0266 ,  A61B18/148 ,  A61B2018/00333 ,  A61B2018/00601 ,  A61B2018/141 ,  A61B2018/1475 ,  A61B2090/3908 ,  A61B2090/3937 ,  A61B2090/395

    摘要： A method of marking an orientation of a cut specimen of tissue prior to excision thereof from a body includes steps of disposing a tissue-marking probe in the body adjacent the cut specimen, the tissue-marking probe including a tissue-marking tool configured to selectively mark the cut specimen. A surface of the cut specimen is then marked with the tissue-marking tool such that the orientation of the cut specimen within the body is discernable after the cut specimen is excised from the body. The tissue-marking tool may be configured to selectively bow out of and back into a window defined near a distal tip of the probe and the marking step may include a step of selectively bowing the tissue-marking tool out of the window and following the surface of the cut specimen while rotating the probe. The tissue-marking tool may include an RF cutting tool and the marking step may include a step of coagulating or cauterizing a selected portion of the surface of the cut specimen with the RF cutting tool. Alternatively, the marking step may include a step of delivering dye onto selected portions of the surface of the cut specimen.

    摘要翻译： 在从身体切除之前标记组织切割样本的取向的方法包括以下步骤：将组织标记探针设置在与切割的样本相邻的身体中，组织标记探针包括组织标记工具，其被配置为选择性地 标记切割标本。 然后用组织标记工具标记切割的样品的表面，使得在切割的样品从身体切除之后，切割的样品在体内的取向是可辨别的。 组织标记工具可以被配置为选择性地弯曲到限定在探针的远侧末端附近的窗口中，并且标记步骤可以包括将组织标记工具选择性地弯曲出窗户并且跟随表面的步骤 同时旋转探头。 组织标记工具可以包括RF切割工具，并且标记步骤可以包括用RF切割工具凝固或烧灼切割样品表面的选定部分的步骤。 或者，标记步骤可以包括将染料递送到切割样品的表面的选定部分上的步骤。

    Excisional biopsy devices and methods
    4.
    发明申请
    Excisional biopsy devices and methods 审中-公开
    切除活检装置和方法

    公开(公告)号：US20050182339A1

    公开(公告)日：2005-08-18

    申请号：US11045006

    申请日：2005-01-26

    申请人： Roberta Lee ,  James Vetter ,  Ary Chernomorsky

    发明人： Roberta Lee ,  James Vetter ,  Ary Chernomorsky

    IPC分类号： A61B10/02 ,  A61B8/12 ,  A61B10/00 ,  A61B10/04 ,  A61B17/22 ,  A61B18/12 ,  A61B18/14 ,  A61B19/00 ,  A61B17/32

    CPC分类号： A61B10/0266 ,  A61B10/0041 ,  A61B10/02 ,  A61B10/04 ,  A61B17/320725 ,  A61B18/1482 ,  A61B2018/00011 ,  A61B2018/00333 ,  A61B2018/1407 ,  A61B2018/1475 ,  A61B2090/3782 ,  A61B2090/3784 ,  A61B2218/002

    摘要： An excisional biopsy system includes a tubular member that has a proximal end and a distal end in which one or more windows are defined. A first removable probe has a proximal portion that includes a cutting tool extender and a distal portion that includes a cutting tool. The first removable probe may be configured to fit at least partially within the tubular member to enable the cutting tool to selectively bow out of and to retract within one of the windows when the cutting tool extender is activated. A second removable probe has a proximal section that includes a tissue collection device extender and a distal section that includes a tissue collection device. The second removable probe may also be configured to fit at least partially within the tubular member to enable the tissue collection device to extend out of and to retract within one of the windows when the tissue collection device extender is activated. A third removable probe may also be provided. The third removable probe may also be configured to fit at least partially within the tubular member and may include an imaging device, such as an ultrasound transducer, mounted therein. By selectively activating the cutting tool and the tissue collection device while rotating the excisional device, a tissue specimen may be cut from the surrounding tissue and collected for later analysis.

    摘要翻译： 切除活检系统包括管状构件，其具有限定一个或多个窗口的近端和远端。 第一可移除探针具有近端部分，其包括切削刀具延伸器和包括切削工具的远端部分。 第一可移除探针可以被配置为至少部分地配合在管状构件内，以使得当切割工具延伸器被激活时，切割工具能够选择性地弯曲在一个窗口内并缩回。 第二可移除探针具有近端部分，其包括组织收集装置延伸器和包括组织收集装置的远端部分。 第二可移除探针也可以被配置为至少部分地配合在管状构件内，以使组织收集装置在组织收集装置延伸器被启动时延伸出窗口内的一个窗口并缩回。 还可以提供第三可移除探针。 第三可移除探针也可以被配置为至少部分地配合在管状构件内，并且可以包括安装在其中的成像装置，例如超声换能器。 通过在旋转切除装置的同时选择性地激活切割工具和组织收集装置，可以从周围组织切割组织标本并收集用于随后的分析。

    Post-biopsy cavity treatmetn implants and methods
    5.
    发明申请
    Post-biopsy cavity treatmetn implants and methods 审中-公开
    活检后治疗植入物和方法

    公开(公告)号：US20050020899A1

    公开(公告)日：2005-01-27

    申请号：US10627960

    申请日：2003-07-25

    申请人： Ary Chernomorsky ,  James Vetter ,  Simon Chernomorsky

    发明人： Ary Chernomorsky ,  James Vetter ,  Simon Chernomorsky

    IPC分类号： A61B19/00 ,  A61K49/04 ,  A61B5/05

    CPC分类号： A61M31/005 ,  A61B17/0057 ,  A61B90/39 ,  A61B2017/00654 ,  A61B2090/3908 ,  A61B2090/3987 ,  A61K49/04 ,  A61L31/146 ,  A61L31/18

    摘要： An embodiment of a post-biopsy cavity treatment implant includes a first portion including a first porous matrix defining a first controlled pore architecture or crosslinking density, and a second portion coupled to the first portion. The second portion includes a second porous matrix that defines a second controlled pore architecture or a second crosslinking density that is different from the first controlled pore architecture or the first crosslinking density, causing the second portion to swell in a different manner than the first portion when the implant is placed in an aqueous environment.

    摘要翻译： 活检后腔腔治疗植入物的实施方案包括第一部分，其包括限定第一受控孔结构或交联密度的第一多孔基质，以及耦合到第一部分的第二部分。 第二部分包括限定第二受控孔结构的第二多孔基质或不同于第一受控孔结构或第一交联密度的第二交联密度，导致第二部分以与第一部分不同的方式膨胀， 将植入物置于含水环境中。

    Post-biopsy cavity treatment implants and methods
    6.
    发明申请
    Post-biopsy cavity treatment implants and methods 失效
    活检后腔内治疗植入物和方法

    公开(公告)号：US20080114329A1

    公开(公告)日：2008-05-15

    申请号：US12018170

    申请日：2008-01-22

    申请人： Ary CHERNOMORSKY ,  James Vetter ,  Simon Chernomorsky

    发明人： Ary CHERNOMORSKY ,  James Vetter ,  Simon Chernomorsky

    IPC分类号： A61M31/00

    CPC分类号： A61L31/146 ,  A61B17/0057 ,  A61B90/39 ,  A61B2017/00654 ,  A61B2090/3908 ,  A61B2090/3925 ,  A61B2090/3987 ,  A61K49/04 ,  A61L31/18

    摘要： A method of treating a cavity created by a percutaneous excisional procedure carried out through an incision includes steps of providing a post-procedure cavity implant, the post-procedure cavity implant including: a radiopaque element; a core portion coupled to the radiopaque element, the core portion including a first porous matrix defining a first controlled pore architecture, and a shell portion coupled to the core portion, the shell portion including a second porous matrix defining a second controlled pore architecture that is different from the first controlled pore architecture; implanting the post-procedure cavity implant into the cavity, and closing the incision.

    摘要翻译： 一种治疗由通过切口进行的经皮切除手术产生的腔的方法包括提供后程腔腔植入物的步骤，所述后程腔腔植入物包括：不透射线的元件; 芯部分，其连接到所述不透射线元件，所述芯部分包括限定第一受控孔结构的第一多孔基体和耦合到所述芯部分的壳部分，所述壳部分包括限定第二受控孔结构的第二多孔基体， 不同于第一受控孔结构; 将后程腔腔植入物植入腔中，并闭合切口。