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公开(公告)号：US20070282202A1
公开(公告)日：2007-12-06
申请号：US10588421
申请日：2005-02-09
申请人： Roch Maurice , Guy Cloutier , Jacques Ohayon , Gilles Soulez
发明人： Roch Maurice , Guy Cloutier , Jacques Ohayon , Gilles Soulez
IPC分类号： A61B8/00
CPC分类号： A61B5/02007 , A61B5/0066 , A61B8/08 , A61B8/0891 , A61B8/485 , A61B8/587 , G06T7/0012 , G06T7/20 , G06T2207/10132 , G06T2207/30101 , G06T2207/30241
摘要： The method for vascular elastography comprises: i) obtaining a sequence of radio-frequency (RF) images including pre-tissue-motion and post-tissue-motion images in digital form of a vessel delimited by a vascular wall; the pre-tissue-motion and post-tissue-motion images being representative of first and second time-delayed configuration, of the whole vessel; ii) partitioning both the pre-tissue-motion and post-tissue-motion images within the vascular wall into corresponding data windows; approximating a trajectory between the pre- and post-tissue-motion for corresponding data windows; and using the trajectory for each data window to compute the full strain tensor in each data window, which allow determining the Von Mises coefficient. The method can be adapted for non-invasive vascular elastography (NIVE), for non-invasive vascular micro-elastography (MicroNIVE) on small vessels, and for endovascular elastography (EVE).
摘要翻译： 用于血管弹性成像的方法包括：i）获得包括由血管壁限定的血管数字形式的组织前运动和组织后运动图像的射频（RF）图像序列; 组织运动和组织后运动图像代表整个血管的第一和第二时间延迟构型; ii）将血管壁内的组织前运动和组织后运动图像分成相应的数据窗口; 逼近相应数据窗口的组织前和组织运动之间的轨迹; 并且使用每个数据窗口的轨迹来计算每个数据窗口中的全应变张量，这允许确定Von Mises系数。 该方法可适用于非侵入性血管弹性成像（NIVE），用于小血管的非侵入性血管微弹性成像（MicroNIVE）和血管内弹性成像（EVE）。
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公开(公告)号：US20100312092A1
公开(公告)日：2010-12-09
申请号：US12590715
申请日：2009-11-12
IPC分类号： A61B5/055
CPC分类号： A61B5/02007 , A61B5/0066 , A61B8/08 , A61B8/0891 , A61B8/485 , A61B8/587 , G06T7/0012 , G06T7/20 , G06T2207/10132 , G06T2207/30101 , G06T2207/30241
摘要： The method for vascular elastography comprises: i) obtaining a sequence of radio-frequency (RF) images including pre-tissue-motion and post-tissue-motion images in digital form of a vessel delimited by a vascular wall; the pre-tissue-motion and post-tissue-motion images being representative of first and second time-delayed configuration, of the whole vessel; ii) partitioning both the pre-tissue-motion and post-tissue-motion images within the vascular wall into corresponding data windows; approximating a trajectory between the pre- and post-tissue-motion for corresponding data windows; and using the trajectory for each data window to compute the full strain tensor in each data window, which allow determining the Von Mises coefficient. The method can be adapted for non-invasive vascular elastography (NIVE), for non-invasive vascular micro-elastography (MicroNlVE) on small vessels, and for endovascular elastography (EVE).
摘要翻译： 用于血管弹性成像的方法包括：i）获得包括由血管壁限定的血管数字形式的组织前运动和组织后运动图像的射频（RF）图像序列; 组织运动和组织后运动图像代表整个血管的第一和第二时间延迟构型; ii）将血管壁内的组织前运动和组织后运动图像分成相应的数据窗口; 逼近相应数据窗口的组织前和组织运动之间的轨迹; 并且使用每个数据窗口的轨迹来计算每个数据窗口中的全应变张量，这允许确定Von Mises系数。 该方法可适用于非侵入性血管弹性成像（NIVE），用于小血管上的非侵入性血管微弹性成像（MicroNlVE）和血管内弹性成像（EVE）。
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3.发明授权公开(公告)号：US07925064B2
公开(公告)日：2011-04-12
申请号：US10579381
申请日：2004-11-15
IPC分类号： G06K9/00
CPC分类号： A61B5/02007 , A61B8/0858 , G06K9/34 , G06K9/6278 , G06K2209/05 , G06T7/12 , G06T7/149 , G06T2207/10132 , G06T2207/20161 , G06T2207/30101
摘要： The present invention generally relates to intravascular ultrasound (IVUS) image segmentation methods, and is more specifically concerned with an intravascular ultrasound image segmentation method for characterizing blood vessel vascular layers. The proposed image segmentation method for estimating boundaries of layers in a multi-layered vessel provides image data which represent a plurality of image elements of the multi-layered vessel. The method also determines a plurality of initial interfaces corresponding to regions of the image data to segment and further concurrently propagates the initial interfaces corresponding to the regions to segment. The method thereby allows to estimate the boundaries of the layers of the multi-layered vessel by propagating the initial interfaces using a fast marching model based on a probability function which describes at least one characteristic of the image elements.
摘要翻译： 本发明一般涉及血管内超声（IVUS）图像分割方法，更具体地涉及用于表征血管血管层的血管内超声图像分割方法。 用于估计多层容器中的层的边界的所提出的图像分割方法提供了表示多层容器的多个图像元素的图像数据。 该方法还确定对应于图像数据的区域的多个初始界面以分段，并且进一步同时地将对应于该区域的初始界面传播到段。 因此，该方法允许通过使用基于描述图像元素的至少一个特征的概率函数的快速行进模型传播初始界面来估计多层容器的层的边界。
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4.发明申请公开(公告)号：US20050123178A1
公开(公告)日：2005-06-09
申请号：US10495407
申请日：2002-11-05
申请人： Pierre Teppaz , Salah Qanadli , Guy Cloutier , Gilles Soulez , Richard Cimon , Louis-Gilles Durand
发明人： Pierre Teppaz , Salah Qanadli , Guy Cloutier , Gilles Soulez , Richard Cimon , Louis-Gilles Durand
CPC分类号： A61B6/583 , A61B5/0035 , A61B5/055 , A61B8/587 , B33Y80/00 , G01R33/58 , G09B23/286
摘要： A multimodality imaging phantom is disclosed which is useful for calibrating devices for imaging vascular conduits. The phantom is compatible with X-ray, ultrasound and magnetic resonance imaging techniques. It allows testing, calibration, and inter-modality comparative study of imaging devices, in static or dynamic flow conditions. It also provides a geometric reference for evaluation of accuracy of imaging devices. The tissue-mimicking material is preferably an agar-based solidified gel. A vessel of known desired geometry runs throughout the gel and is connected to an inlet and outlet at its extremities for generating a flow circulation in the vessel. Said phantom also contains fiducial markers detectable in the above-mentioned modalities. The markers are preferably made of glass and are embedded in a layer of agar gel containing a fat component. The markers are implanted at precise known locations to allow identification and orientation of plane views, and they can be used for calibration, resealing and fusion of 3D images obtained from different modalities, and 3D image reconstruction from angiographic plane views. Also disclosed is a process for manufacturing said phantom.
摘要翻译： 公开了一种多模态成像体模，其用于校准用于成像血管导管的装置。 幻影与X射线，超声和磁共振成像技术兼容。 它允许在静态或动态流动条件下的成像装置的测试，校准和模式间比较研究。 它还提供了用于评估成像设备精度的几何参考。 组织模拟材料优选为基于琼脂的固化凝胶。 具有已知所需几何形状的容器在整个凝胶中运行，并连接到其末端的入口和出口，以在容器中产生流动循环。 所述幻影还包含在上述方式中可检测的基准标记。 标记物优选由玻璃制成并嵌入含有脂肪成分的琼脂凝胶层中。 标记植入在精确的已知位置以允许平面视图的识别和取向，并且它们可用于从不同模态获得的3D图像的校准，重新密封和融合以及来自血管造影平面视图的3D图像重建。 还公开了用于制造所述体模的方法。
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5.发明授权公开(公告)号：US07439493B2
公开(公告)日：2008-10-21
申请号：US10495407
申请日：2002-11-05
申请人： Pierre Teppaz , Salah Dine Qanadli , Guy Cloutier , Gilles Soulez , Richard Cimon , Louis-Gilles Durand
发明人： Pierre Teppaz , Salah Dine Qanadli , Guy Cloutier , Gilles Soulez , Richard Cimon , Louis-Gilles Durand
IPC分类号： G01D18/00
CPC分类号： A61B6/583 , A61B5/0035 , A61B5/055 , A61B8/587 , B33Y80/00 , G01R33/58 , G09B23/286
摘要： A multimodality imaging phantom is disclosed which is useful for calibrating devices for imaging vascular conduits. The phantom is compatible with X-ray, ultrasound and magnetic resonance imaging techniques. It allows testing, calibration, and inter-modality comparative study of imaging devices, in static or dynamic flow conditions. It also provides a geometric reference for evaluation of accuracy of imaging devices. The tissue-mimicking material is preferably an agar-based solidified gel. A vessel of known desired geometry runs throughout the gel and is connected to an inlet and outlet at its extremities for generating a flow circulation in the vessel. Said phantom also contains fiducial markers detectable in the above-mentioned modalities. The markers are preferably made of glass and are embedded in a layer of agar gel containing a fat component. The markers are implanted at precise known locations to allow identification and orientation of plane views, and they can be used for calibration, resealing and fusion of 3D images obtained from different modalities, and 3D image reconstruction from angiographic plane views. Also disclosed is a process for manufacturing said phantom.
摘要翻译： 公开了一种多模态成像体模，其用于校准用于成像血管导管的装置。 幻影与X射线，超声和磁共振成像技术兼容。 它允许在静态或动态流动条件下的成像装置的测试，校准和模式间比较研究。 它还提供了用于评估成像设备精度的几何参考。 组织模拟材料优选为基于琼脂的固化凝胶。 具有已知所需几何形状的容器在整个凝胶中运行，并连接到其末端的入口和出口，以在容器中产生流动循环。 所述幻影还包含在上述方式中可检测的基准标记。 标记物优选由玻璃制成并嵌入含有脂肪成分的琼脂凝胶层中。 标记植入在精确的已知位置以允许平面视图的识别和取向，并且它们可用于从不同模态获得的3D图像的校准，重新密封和融合以及来自血管造影平面视图的3D图像重建。 还公开了用于制造所述体模的方法。
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6.发明申请公开(公告)号：US20070165916A1
公开(公告)日：2007-07-19
申请号：US10579381
申请日：2004-11-15
IPC分类号： G06K9/00
CPC分类号： A61B5/02007 , A61B8/0858 , G06K9/34 , G06K9/6278 , G06K2209/05 , G06T7/12 , G06T7/149 , G06T2207/10132 , G06T2207/20161 , G06T2207/30101
摘要： The present invention generally relates to intravascular ultrasound (IVUS) image segmentation methods, and is more specifically concerned with an intravascular ultrasound image segmentation method for characterizing blood vessel vascular layers. The proposed image segmentation method for estimating boundaries of layers in a multi-layered vessel provides image data which represent a plurality of image elements of the multi-layered vessel. The method also determines a plurality of initial interfaces corresponding to regions of the image data to segment and further concurrently propagates the initial interfaces corresponding to the regions to segment. The method thereby allows to estimate the boundaries of the layers of the multi-layered vessel by propagating the initial interfaces using a fast marching model based on a probability function which describes at least one characteristic of the image elements.
摘要翻译： 本发明一般涉及血管内超声（IVUS）图像分割方法，更具体地涉及用于表征血管血管层的血管内超声图像分割方法。 用于估计多层容器中的层的边界的所提出的图像分割方法提供了表示多层容器的多个图像元素的图像数据。 该方法还确定对应于图像数据的区域的多个初始界面以分段，并且进一步同时地将对应于该区域的初始界面传播到段。 因此，该方法允许通过使用基于描述图像元素的至少一个特征的概率函数的快速行进模型传播初始界面来估计多层容器的层的边界。
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公开(公告)号：US20080108898A1
公开(公告)日：2008-05-08
申请号：US11867234
申请日：2007-10-04
申请人： Ali MEGHOUFEL , Jacques De Guise , Guy Cloutier
发明人： Ali MEGHOUFEL , Jacques De Guise , Guy Cloutier
IPC分类号： A61B8/00
CPC分类号： A61B8/08 , A61B5/4523 , A61B5/4533 , A61B8/14 , A61B8/483 , G06T7/11 , G06T7/155 , G06T17/00 , G06T2207/10132 , G06T2207/30024
摘要： A method for producing models of fibrous structure of fibrous tissue comprises obtaining a sequence of two-dimensional ultrasound images along the fibrous tissue. A three-dimensional model of an external portion of the fibrous tissue is created using the two-dimensional ultrasound images. Selected fibrous structure data is segmented from the two-dimensional ultrasound images. A three-dimensional model of the fibrous tissue is created with the fibrous structure by combining the three-dimensional model of the external portion of the fibrous tissue with the selected fibrous structure data.
摘要翻译： 用于生产纤维组织的纤维结构模型的方法包括沿纤维组织获得二维超声图像序列。 使用二维超声图像产生纤维组织的外部部分的三维模型。 选择的纤维结构数据从二维超声图像分割。 通过将纤维组织的外部部分的三维模型与所选择的纤维结构数据相结合，通过纤维结构产生纤维组织的三维模型。
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公开(公告)号：US08600128B2
公开(公告)日：2013-12-03
申请号：US12558786
申请日：2009-09-14
申请人： François Destrempes , Guy Cloutier , Jean Meunier
发明人： François Destrempes , Guy Cloutier , Jean Meunier
IPC分类号： G06K9/00
CPC分类号： G06T7/143 , G06T7/12 , G06T2207/10132 , G06T2207/20096 , G06T2207/30101
摘要： A method for segmenting an image comprising: determining an initial estimation of a boundary between at least two components in a region of an image to be segmented; providing image data from the region of the image to be segmented, the image data representing gray level values of a plurality of image elements of the components; modelling the image data on a mixture of at least two statistical distributions, each statistical distribution having more than one parameter, and each component being associated with certain weights of the statistical distributions in the mixture; estimating the parameters of the statistical distributions in the mixture; for each component, estimating the weights of the statistical distributions in the mixture based on the estimated parameters and the image data of each image element; and optimizing the initial estimation of the boundary between the components based on the estimated parameters and estimated weights.
摘要翻译： 一种用于分割图像的方法，包括：确定要分割的图像的区域中的至少两个分量之间的边界的初始估计; 从要分割的图像的区域提供图像数据，所述图像数据表示所述分量的多个图像元素的灰度值; 对至少两个统计分布的混合物对图像数据进行建模，每个统计分布具有多于一个参数，并且每个分量与混合物中的统计分布的某些权重相关联; 估计混合物中统计分布的参数; 对于每个组件，基于估计的参数和每个图像元素的图像数据估计混合中的统计分布的权重; 并且基于估计的参数和估计的权重优化组件之间的边界的初始估计。
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公开(公告)号：US09389204B2
公开(公告)日：2016-07-12
申请号：US12595649
申请日：2008-04-10
申请人： Guy Cloutier , François Yu , Emilie Franceschini , David Savery
发明人： Guy Cloutier , François Yu , Emilie Franceschini , David Savery
CPC分类号： G01N29/069 , A61B8/06 , A61B8/13 , G01N29/4418 , G01N29/4472 , G01N2291/014 , G01N2291/02408 , G01N2291/02416 , G01N2291/02466 , G01N2291/02836 , G01S7/52036
摘要： A method for characterizing ultrasound scatterers in a medium comprising providing ultrasound data representing a region of interest comprising a plurality of scatterers in a medium, the plurality of scatterers including clusters of scatterer sub-units, the scatterers having a physical property value to be estimated and the scatterer sub-units having at least one known physical parameter value; modelling the ultrasound data using an at least second order function of a spatial organization parameter defining the spatial organization of the scatterers; and estimating the physical property value of the scatterers from the modelled ultrasound data and the at least one known physical parameter of the sub-units by a regression of the spatial organization parameter as a function of frequency. A system for characterizing ultrasound scatterers is also included.
摘要翻译： 一种用于表征介质中的超声波散射体的方法，包括提供表示在介质中包括多个散射体的感兴趣区域的超声数据，所述多个散射体包括散射体子单元的簇，所述散射体具有待估计的物理属性值， 具有至少一个已知物理参数值的散射体子单元; 使用定义散射体的空间组织的空间组织参数的至少二阶函数对超声数据建模; 以及通过作为频率的函数的空间组织参数的回归，从建模的超声数据和子单元的至少一个已知物理参数估计散射体的物理属性值。 还包括用于表征超声波散射体的系统。
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10.发明申请SYSTEM AND METHOD FOR DETECTION, CHARACTERIZATION AND IMAGING OF HETEROGENEITY USING SHEAR WAVE INDUCED RESONANCE 审中-公开使用剪切波诱导谐振检测，表征和成像异构体的系统和方法公开(公告)号：US20110130660A1
公开(公告)日：2011-06-02
申请号：US13056224
申请日：2009-07-30
IPC分类号： A61B8/00
CPC分类号： A61B8/406 , A61B5/0051 , A61B5/0057 , A61B5/02007 , A61B8/08 , A61B8/0825 , A61B8/4218 , A61B8/4405 , A61B8/4461 , A61B8/485 , A61B8/5215 , A61B8/587 , A61N7/02 , G01H13/00 , G01N29/0654 , G01N29/12 , G01N2291/02475 , G01N2291/0422
摘要： A system and a method for inducing resonance of a heterogeneity or a sample within a body, the system comprising a shear wave generator, and a detection unit; the shear wave generator generating shear waves applied to the body and selectively inducing mechanical resonances of the heterogeneity, the detection unit detecting the induced mechanical resonances. The induced resonance of the heterogeneity is achieved by applying to the body one of: i) shear waves substantially parallel to a longitudinal axis of the heterogeneity; ii) shear waves polarised substantially perpendicularly to said longitudinal axis; iii) shear waves substantially circumferential to the heterogeneity; and iv) planar shear waves.
摘要翻译： 一种用于诱发体内异质性或样品共振的系统和方法，所述系统包括剪切波发生器和检测单元; 剪切波发生器产生施加到身体的剪切波并选择性地诱导异质性的机械共振，检测单元检测感应的机械共振。 不均匀性的诱导共振通过向身体施加以下一个来实现：i）基本上平行于异质性的纵轴的剪切波; ii）基本上垂直于所述纵向轴线偏振的剪切波; iii）基本上与异质性圆周的剪切波; 和iv）平面剪切波。
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