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公开(公告)号：US20240371479A1
公开(公告)日：2024-11-07
申请号：US18636375
申请日：2024-04-16
Applicant: Roche Diagnostics Operations, Inc.
Inventor： Michael Glauser , Oliver Gutmann , Gabriele Piero Janner , Emad Sarofim , Stephan Schweighauser , Marcel Thomann , Urs Vollenweider
IPC: G16H10/40
Abstract: A computer-implemented method for optimising an assignment of one or more medical samples to one or more analytical tests to be conducted on those medical samples. The method comprises the steps of: obtaining an initial assignment of the one or more medical samples to the one or more analytical tests; determining a compliance status for the or each medical sample, the compliance status indicating: (i) whether a sample quality metric of the or each medical sample violates an analytical test specification of the medical sample's assigned analytical test(s) in the initial assignment and/or (ii) whether the or each medical sample is unprocessable; and performing a mitigation action if one or more compliance status indicate: (i) that the sample quality metric of a given medical sample violates the analytical test specification and/or (ii) a given medical sample is unprocessable.
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公开(公告)号：US20230258680A1
公开(公告)日：2023-08-17
申请号：US18137254
申请日：2023-04-20
Inventor： Andreas Drechsler , Oliver Gutmann , Melis Hazar , Reto Huesser , Raymond T. Kozikowski, III , Daniel Mueller , Chris Steinert
CPC classification number: G01N35/1016 , G01N1/312 , G01N35/1002 , G01N35/1011 , G01N35/1009 , G01N2001/317 , G01N2035/1041
Abstract: A system and method for treatment of biological samples is disclosed. In some embodiments, an automated biological sample staining system (100), comprising at least one microfluidic reagent applicator (118); at least one bulk fluid applicator (116); at least one fluid aspirator; at least one sample substrate holder; at least one relative motion system; and a control system (102) that is programmed to execute at least one staining protocol on a sample mounted on a substrate that is held in the at least one sample substrate holder.
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Patent Agency Ranking
公开(公告)号：US11668726B2
公开(公告)日：2023-06-06
申请号：US16388797
申请日：2019-04-18
Inventor： Andreas Drechsler , Oliver Gutmann , Melis Hazar , Reto Huesser , Raymond T. Kozikowski, III , Daniel Mueller , Chris Steinert
CPC classification number: G01N35/1016 , G01N1/312 , G01N35/1002 , G01N35/1009 , G01N35/1011 , G01N2001/317 , G01N2035/1041
Abstract: A system and method for treatment of biological samples is disclosed. In some embodiments, an automated biological sample staining system (100), comprising at least one microfluidic reagent applicator (118); at least one bulk fluid applicator (116); at least one fluid aspirator; at least one sample substrate holder; at least one relative motion system; and a control system (102) that is programmed to execute at least one staining protocol on a sample mounted on a substrate that is held in the at least one sample substrate holder.
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4.发明申请公开(公告)号：US20190285660A1
公开(公告)日：2019-09-19
申请号：US16291562
申请日：2019-03-04
Applicant: Roche Diagnostics Operations, Inc.
Inventor： Martin Kopp , Oliver Gutmann , Norbert Schmitt
Abstract: A laboratory system for a laboratory automation system is presented. The laboratory system comprises a sample container carrier. The sample container carrier is configured to carry a laboratory sample container and comprises a removal detector. The removal detector is configured to interact with the laboratory sample container to detect a removal of the carried laboratory sample container from the sample container carrier. Furthermore, the laboratory system is configured to determine based on the detected removal that a before valid logic assignment of the sample container carrier to the carried laboratory sample container is invalid.
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公开(公告)号：US09606140B2
公开(公告)日：2017-03-28
申请号：US14286194
申请日：2014-05-23
Applicant: Roche Diagnostics Operations, Inc.
Inventor： Geza Burghardt , Michael Glauser , Oliver Gutmann , Daniel Mueller , Edwin Oosterbroek , Roger Sandoz , Emad Sarofim , Goran Savatic
CPC classification number: G01P15/02 , B01L3/5021 , B01L3/5453 , B01L2200/14 , B01L2200/143 , B01L2300/021 , B01L2300/025 , B01L2300/0663 , B01L2400/0409
Abstract: An acceleration sensitive indicator for indicating a centrifugation status of a biological sample, a sample container comprising the indicator, a centrifuge for centrifuging samples and an analytical system for analyzing centrifuged samples are disclosed. The indicator comprises at least one closed chamber, formed between two opposite surfaces, that comprises an indication zone that comprises at least two fluid transfer zones or at least one particle transfer zone. The at least one fluid transfer zone comprises a solid carrier phase and a fluid stabilized in the solid carrier phase or at least one non-stabilized non-Newtonian fluid having thixotropic and/or shear thinning properties. The at least one particle transfer zone comprises a particle stabilizing fluid comprising stabilized dispersed particles. The fluid or particles have a distribution with respect to the indication zone changeable upon application of a g-force above a threshold value, the change of distribution indicating the centrifugation status.
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6.发明授权公开(公告)号：US11709171B2
公开(公告)日：2023-07-25
申请号：US16291562
申请日：2019-03-04
Applicant: Roche Diagnostics Operations, Inc.
Inventor： Martin Kopp , Oliver Gutmann , Norbert Schmitt
CPC classification number: G01N35/00732 , G01N35/04 , G01R33/0035 , G01N2035/00633 , G01N2035/00643 , G01N2035/00762 , G01N2035/00801 , G01N2035/0401 , G01N2035/0477
Abstract: A laboratory system for a laboratory automation system is presented. The laboratory system comprises a sample container carrier. The sample container carrier is configured to carry a laboratory sample container and comprises a removal detector. The removal detector is configured to interact with the laboratory sample container to detect a removal of the carried laboratory sample container from the sample container carrier. Furthermore, the laboratory system is configured to determine based on the detected removal that a before valid logic assignment of the sample container carrier to the carried laboratory sample container is invalid.
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公开(公告)号：US20190242921A1
公开(公告)日：2019-08-08
申请号：US16388797
申请日：2019-04-18
Inventor： Andreas Drechsler , Oliver Gutmann , Melis Hazar , Reto Huesser , Raymond T. Kozikowski, III , Daniel Mueller , Chris Steinert
CPC classification number: G01N35/1016 , G01N1/312 , G01N35/1002 , G01N35/1009 , G01N35/1011 , G01N2001/317 , G01N2035/1041
Abstract: A system and method for treatment of biological samples is disclosed. In some embodiments, an automated biological sample staining system (100), comprising at least one microfluidic reagent applicator (118); at least one bulk fluid applicator (116); at least one fluid aspirator; at least one sample substrate holder; at least one relative motion system; and a control system (102) that is programmed to execute at least one staining protocol on a sample mounted on a substrate that is held in the at least one sample substrate holder.
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