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44 条记录 (耗时 0.025 秒)

    Post-surgical anti-adhesion device
    1.
    发明授权
    Post-surgical anti-adhesion device 失效
    手术后抗粘连装置

    公开(公告)号：US5795584A

    公开(公告)日：1998-08-18

    申请号：US385007

    申请日：1995-02-07

    申请人： Nagabhushanam Totakura ,  Ross R. Muth ,  Roy D. Gravener ,  Matthew Hain ,  Ilya S. Koyfman

    发明人： Nagabhushanam Totakura ,  Ross R. Muth ,  Roy D. Gravener ,  Matthew Hain ,  Ilya S. Koyfman

    IPC分类号： A61L31/06 ,  A61L31/14 ,  A61K9/70

    CPC分类号： A61L31/148 ,  A61L31/06 ,  Y10S602/904

    摘要： Surgical adhesion barriers and methods of using such surgical adhesion barriers are provided. Surgical adhesion barriers according to the present invention have at least one layer of a bioabsorbable material comprising copolymers and/or block copolymers derived from trimethylene carbonate. Alternatively, a multilayer surgical structure having one or more bioabsorbable layers superimposed on a non-absorbable layer is useful for minimizing or preventing formation of fibrous adhesions between a healing trauma site and adjacent surrounding tissue. Alternatively, a bioabsorbable non-woven fabric in adherent contact with at least one bioabsorbable layer of foam, film, mesh, web or woven fabric is also provided. One or more medicinal agents may be interposed between or disposed within any of the aforementioned layers.

    摘要翻译： 提供了外科粘连屏障和使用这种手术粘合屏障的方法。 根据本发明的手术粘合屏障具有至少一层生物可吸收材料，其包含衍生自三亚甲基碳酸酯的共聚物和/或嵌段共聚物。 或者，具有叠加在不可吸收层上的一个或多个生物可吸收层的多层手术结构可用于最小化或防止愈合创伤部位与相邻周围组织之间的纤维粘连的形成。 或者，还提供了与泡沫，膜，网，网或机织织物的至少一个生物可吸收层粘附接触的生物可吸收性无纺织物。 一种或多种药剂可插入或设置在任何上述层内。

    Forming latchless surgical clip and fixture for use therein
    4.
    发明授权
    Forming latchless surgical clip and fixture for use therein 失效
    形成无闩锁手术夹具和夹具用于其中

    公开(公告)号：US5474732A

    公开(公告)日：1995-12-12

    申请号：US281885

    申请日：1994-07-28

    申请人： Herbert W. Korthoff ,  Daniel Shichman ,  Ross R. Muth ,  Charles E. Gorman, Jr.

    发明人： Herbert W. Korthoff ,  Daniel Shichman ,  Ross R. Muth ,  Charles E. Gorman, Jr.

    IPC分类号： A61B17/122 ,  F16B2/22 ,  B29C61/06 ,  B29C59/18

    CPC分类号： F16B2/22 ,  A61B17/122

    摘要： A method for forming a surgical clip and fixture for use therein includes molding a polymeric clip body, the clip body having hinged legs, the polymer of the clip body being substantially amorphous. The clip body can then be moved to a desired configuration while being subjected to a temperature above the glass transition temperature. The molded clip body is then heated to a temperature within the crystallization range for a period of time sufficient to impart at least 20% crystallinity thereto to impart a spring back property. Also disclosed herein is a fixture for forming a surgical clip in accordance with this method.

    摘要翻译： 用于形成用于其中的手术夹子和夹具的方法包括模制聚合物夹体，夹体具有铰接的腿，夹体的聚合物基本上是无定形的。 然后可以将夹子主体移动到期望的构造，同时经受高于玻璃化转变温度的温度。 然后将模制夹体加热至结晶范围内的温度一段足以给其至少20％结晶度的时间以赋予回弹性能。 本文还公开了根据该方法形成外科夹的夹具。

    Method for improving the storage stability of a polymeric article susceptible to hydrolytic degradation and resulting article
    9.
    发明授权
    Method for improving the storage stability of a polymeric article susceptible to hydrolytic degradation and resulting article 失效
    改善易受水解降解和最终制品影响的聚合物制品的储存稳定性的方法

    公开(公告)号：US5051272A

    公开(公告)日：1991-09-24

    申请号：US221308

    申请日：1988-07-19

    申请人： Matthew E. Hermes ,  Ross R. Muth

    发明人： Matthew E. Hermes ,  Ross R. Muth

    IPC分类号： A01N37/36 ,  A61L17/14 ,  A61L27/58 ,  A61L31/14

    CPC分类号： A61L31/148 ,  A01N37/36 ,  A61L17/14 ,  A61L27/58 ,  Y10T428/31504

    摘要： The storage stability of a polymeric article susceptible to hydrolytic degradation, e.g., an absorbable suture, is improved by applying a storage stabilizing amount of a mixture comprising at least one water soluble hygroscopic polyhydroxy compound and/or ester thereof, e.g., glycerol, monoacetin, diacetin, and the like, and at least one compound having the general formula ##STR1## and hydreates thereof to the article as storage stabilizing agent, said agent being retained by the article prior to sealing of the enclosure in which the suture is packaged.

    摘要翻译： 通过施加储存稳定量的包含至少一种水溶性吸湿性多羟基化合物和/或其酯的混合物，例如甘油，单醋酸甘油酯， 二乙酸甘油酯等，以及至少一种具有通式“IMAGE”的化合物和其水合物作为储存稳定剂的制品，所述试剂在密封缝合线封装的外壳之前由制品保留。