公开(公告)号：US20230011382A1

公开(公告)日：2023-01-12

申请号：US17783831

申请日：2020-12-10

Applicant: S.D. Sight Diagnostics Ltd.

Inventor： Dan GLUCK ,  Amir ZAIT ,  Arnon HOURI YAFIN ,  Yonatan HALPERIN ,  Yochay Shlomo ESHEL ,  Sarah LEVY ,  Joseph Joel POLLAK ,  Sharon PECKER ,  Peretz YAFIN ,  Dana BENBASSAT ,  David BRAILOVSKY ,  Uriyah PUMERANTZ

IPC: G02B21/00 ,  G06T7/00

Abstract: Apparatus and methods are described use with a bodily sample that contains cells. A microscope (24) is focused, such that a focal plane of the microscope (24) at least approximately coincides with a level at which at least some cells belonging to the sample are at least partially disposed. At least one on-focus microscopic image of the sample, while the focal plane of the microscope (24) approximately coincides with the level. The microscope (24) is focused such that the focal plane of the microscope is offset with respect to the level, at least one off-focus microscopic image of the sample is acquired, while the focal plane of the microscope (24) is offset with respect to the level. A property of at least a portion of the sample is determined, at least partially based upon the on-focus and off-focus images. Other applications are also described.

公开(公告)号：US20230003622A1

公开(公告)日：2023-01-05

申请号：US17783930

申请日：2020-12-10

Applicant: S.D. SIGHT DIAGNOSTICS LTD

Inventor： Peretz YAFIN ,  Dan GLUCK ,  Amir ZAIT ,  Yochay Shlomo ESHEL ,  Sarah LEVY ,  Joseph Joel POLLAK

IPC: G01N1/28 ,  G01N15/14

Abstract: Apparatus and methods are provided including imaging a blood sample that is a cell suspension deposited in a sample chamber. The cells are allowed to settle in the sample chamber to form a monolayer of cells. At least one microscopic image is acquired of the monolayer of cells using a microscope (24) while the microscope is focused at a monolayer-depth-level, and a first platelet count of platelets that have settled within the monolayer, is determined. An additional microscopic image of the simple is acquired, while the microscope is focused at a different depth level from the monolayer-depth-level, and a second platelet count of platelets that have not settled within the monolayer is determined. An output is generated based upon the first and second platelet counts. Other applications are also described.