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公开(公告)号：US20190091694A1
公开(公告)日：2019-03-28
申请号：US16199261
申请日：2018-11-26
申请人： STAR ARRAY PTE LTD
发明人： Haiqing GONG , Yan WEN , Xudong ZENG
CPC分类号： B01L7/5255 , B01F11/0005 , B01L3/5027 , B01L3/5082 , B01L7/02 , B01L7/52 , B01L9/00 , B01L9/06 , B01L2200/025 , B01L2200/06 , B01L2200/14 , B01L2300/0618 , B01L2300/0627 , B01L2300/0816 , B01L2300/0829 , B01L2300/0832 , B01L2300/0858 , B01L2300/1805 , B01L2300/1827 , B01L2300/185 , B01L2300/1894 , B01L2400/065 , C12Q1/6848 , C12Q1/686 , G01N35/00584 , G01N35/04 , G01N2035/00366 , G01N2035/00386 , G01N2035/00396 , G01N2035/0412
摘要： A method and an apparatus for thermal processing of nucleic acid in a thermal profile. The method employs at least a first bath and a second bath, the method further employing a reactor holder for holding reactor(s) accommodating reaction material containing the nucleic acid. The method includes maintaining bath mediums in the baths at two different temperatures; and alternately allowing the reactor(s) to be in the two baths in a plurality of thermal cycles to alternately attain a predetermined high target temperature THT, and a predetermined low target temperature TLT, wherein the bath medium in at least one of the baths is a high thermal conductivity powder.
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公开(公告)号：US20190134639A1
公开(公告)日：2019-05-09
申请号：US16211246
申请日：2018-12-06
申请人： STAR ARRAY PTE LTD
发明人： Haiqing GONG , Yan WEN , Xudong ZENG
摘要： An apparatus for thermal processing of nucleic acid in a thermal profile. The apparatus employs a reactor holder for holding reactors to accommodate reaction material containing nucleic acid. The apparatus includes at least two baths separated by thermally insulating partition plate(s) where bath mediums are each maintainable at a predetermined temperature; and a transfer means for allowing the reactors to change position once or plurality of times between any two adjacent baths by selectively opening the partition plate(s) and without lifting the reactors out of the baths.
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公开(公告)号：US20190105656A1
公开(公告)日：2019-04-11
申请号：US16211257
申请日：2018-12-06
申请人： STAR ARRAY PTE LTD
发明人： Haiqing GONG , Yan WEN , Xudong ZENG
摘要： An apparatus for thermal processing nucleic acid in a thermal profile. The apparatus employs a reactor holder for holding reactor(s) each accommodating reaction material containing the nucleic acid. The apparatus includes a first bath; and a second bath, bath mediums in the baths being respectively maintainable at two different temperatures; and a transfer means for allowing the reactor(s) to be in the two baths in a plurality of thermal cycles to alternately attain: a predetermined high target temperature THT, and a predetermined low target temperature TLT; and reciprocating means to enable relative reciprocating motion between the holder and at least one bath while the reactor(s) is/are placed in the at least one bath, the relative reciprocating motion being executable by shaking the bath or the holder or both.
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公开(公告)号：US20190111435A1
公开(公告)日：2019-04-18
申请号：US16215626
申请日：2018-12-10
申请人： STAR ARRAY PTE LTD
发明人： Haiqing GONG , Yan WEN , Xudong ZENG
摘要： An apparatus for thermally processing reaction material containing nucleic acid is provided. A reaction material is contained in reactors. The apparatus includes a reactor holder for statically holding the reactors; at least two heating means each being maintainable at a user specifiable temperature; and a transport means for positioning the heating means to make a contact with the reactors one at a time for specified duration. The positioning is conductable once or over a plurality of times for thermally processing the reactors between a plurality of temperatures.
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公开(公告)号：US20190118184A1
公开(公告)日：2019-04-25
申请号：US16093970
申请日：2017-06-09
申请人： STAR ARRAY PTE LTD
发明人： Haiqing GONG , Yan WEN , Xudong ZENG
摘要： Apparatus and method for thermal processing of nucleic acid in a thermal profile is provided. The apparatus employs a reactor holder for holding reactor(s) each accommodating reaction material containing the nucleic acid. The apparatus comprises a first bath; and a second bath, bath mediums in the baths being respectively maintainable at two different temperatures THIGH and TLOW; and a transfer means for allowing the reactor(s) to be in the two baths in a plurality of thermal cycles to alternately attain: a predetermined high target temperature THT, and a predetermined low target temperature TLT, while the apparatus adapts to a temperature-offset feature defined by at least one condition from the group consisting: a) the THT is lower than the THIGH, b) the TLT is higher than the TLOW, and c) the conditions at a) and b).
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