公开(公告)号：US09932305B2

公开(公告)日：2018-04-03

申请号：US14371333

申请日：2013-01-08

Applicant: STUDIENGESELLSCHAFT KOHLE MBH

Inventor： Benjamin List ,  Ilija Coric ,  Saihu Liao

IPC: C07C315/02 ,  B01J31/02 ,  C07B53/00 ,  C07B45/04 ,  C07D493/10 ,  C07F9/6571 ,  C07F9/6574

CPC classification number: C07C315/02 ,  B01J31/0258 ,  B01J31/0264 ,  B01J2231/70 ,  C07B45/04 ,  C07B53/00 ,  C07B2200/07 ,  C07C2601/14 ,  C07C2602/08 ,  C07D493/10 ,  C07F9/657154 ,  C07F9/65744 ,  C07C317/14 ,  C07C317/22 ,  C07C317/12 ,  C07C317/04 ,  C07C317/44

Abstract: The present invention relates to a process for the asymmetric oxidation of nucleophilic organic compounds, particularly metal-free, with peroxide compounds in the presence of a chiral Brønsted acid catalyst. In one detail, the present invention relates to a process for enantioselective sulfoxidation of thiocompounds with peroxide compounds in the presence of a chiral imidodiphosphate catalyst. In another detail, the present invention relates to a process for enantioselective sulfoxidation of thiocompounds with peroxide compounds in the presence of a chiral phosphoric acid catalyst.

公开(公告)号：US20140350268A1

公开(公告)日：2014-11-27

申请号：US14371238

申请日：2013-01-08

Applicant: STUDIENGESELLSCHAFT KOHLE MBH

Inventor： Benjamin List ,  Ilija Coric ,  Sreekumar Vellalath

IPC: C07F9/6574 ,  C07D493/10 ,  B01J31/02

CPC classification number: C07F9/65746 ,  B01J31/0264 ,  B01J31/0271 ,  B01J2231/52 ,  B01J2231/70 ,  C07C231/06 ,  C07D209/08 ,  C07D209/12 ,  C07D239/90 ,  C07D307/10 ,  C07D307/20 ,  C07D319/08 ,  C07D327/06 ,  C07D339/08 ,  C07D493/10 ,  C07F9/657154 ,  C07F9/65744 ,  C07C233/05

Abstract: The invention relates to chiral imidodiphosphates and derivatives thereof having the general formula I, The compounds are suitable as chiral Brønsted acid catalysts, phase-transfer catalysts, chiral anions for organic salts, metal salts or metal complexes for catalysis.

Abstract translation: 本发明涉及具有通式I的手性亚氨基二磷酸酯及其衍生物。该化合物适合作为手性布朗斯台德酸催化剂，相转移催化剂，有机盐的手性阴离子，用于催化的金属盐或金属配合物。

公开(公告)号：US09783561B2

公开(公告)日：2017-10-10

申请号：US14371238

申请日：2013-01-08

Applicant: STUDIENGESELLSCHAFT KOHLE MBH

Inventor： Benjamin List ,  Ilija Coric ,  Sreekumar Vellalath

IPC: C07F9/6574 ,  B01J31/02 ,  C07F9/6571 ,  C07D493/10 ,  C07D319/08 ,  C07D327/06 ,  C07D339/08 ,  C07D239/90 ,  C07C231/06 ,  C07D209/08 ,  C07D209/12 ,  C07D307/10 ,  C07D307/20

CPC classification number: C07F9/65746 ,  B01J31/0264 ,  B01J31/0271 ,  B01J2231/52 ,  B01J2231/70 ,  C07C231/06 ,  C07D209/08 ,  C07D209/12 ,  C07D239/90 ,  C07D307/10 ,  C07D307/20 ,  C07D319/08 ,  C07D327/06 ,  C07D339/08 ,  C07D493/10 ,  C07F9/657154 ,  C07F9/65744 ,  C07C233/05

Abstract: The invention relates to chiral imidodiphosphates and derivatives thereof having the general formula I, The compounds are suitable as chiral Brønsted acid catalysts, phase-transfer catalysts, chiral anions for organic salts, metal salts or metal complexes for catalysis.

公开(公告)号：US20150005527A1

公开(公告)日：2015-01-01

申请号：US14371333

申请日：2013-01-08

Applicant: STUDIENGESELLSCHAFT KOHLE MBH

Inventor： Benjamin List ,  Ilija Coric ,  Saihu Liao

IPC: C07C315/02 ,  B01J31/02

CPC classification number: C07C315/02 ,  B01J31/0258 ,  B01J31/0264 ,  B01J2231/70 ,  C07B45/04 ,  C07B53/00 ,  C07B2200/07 ,  C07C2601/14 ,  C07C2602/08 ,  C07D493/10 ,  C07F9/657154 ,  C07F9/65744 ,  C07C317/14 ,  C07C317/22 ,  C07C317/12 ,  C07C317/04 ,  C07C317/44

Abstract: The present invention relates to a process for the asymmetric oxidation of nucleophilic organic compounds, particularly metal-free, with peroxide compounds in the presence of a chiral Brønsted acid catalyst. In one detail, the present invention relates to a process for enantioselective sulfoxidation of thiocompounds with peroxide compounds in the presence of a chiral imidodiphosphate catalyst. In another detail, the present invention relates to a process for enantioselective sulfoxidation of thiocompounds with peroxide compounds in the presence of a chiral phosphoric acid catalyst.

Abstract translation: 本发明涉及在手性布朗斯台德酸催化剂存在下用过氧化物化合物对亲核有机化合物，特别是不含金属的不对称氧化的方法。 一方面，本发明涉及一种在手性酰亚胺二磷酸盐催化剂存在下用过氧化物化合物对硫代化合物进行对映选择性磺基氧化的方法。 另一个细节，本发明涉及在手性磷酸催化剂存在下用过氧化物化合物对硫代化合物进行对映选择性磺基氧化的方法。