公开(公告)号：US20230131993A1

公开(公告)日：2023-04-27

申请号：US17909342

申请日：2020-03-06

Applicant: SYMRISE AG

Inventor： Sabine Lange ,  Martina Herrmann ,  Sebastian Bruncke ,  Holger Joppe ,  Kalpana Palani

IPC: A61K31/196 ,  A61K36/899 ,  A61K47/12 ,  A61K47/10 ,  A61K47/08 ,  A61K8/9794 ,  A61Q17/04 ,  A61Q19/00

Abstract: The present invention relates generally to: a composition comprising or consisting at least one avenanthramide or an analogue thereof or an oat extract comprising an avenanthramide or an analogue thereof with an improved stability; its cosmetic or medical use; the use of such composition for the preparation of foods, food supplements, cosmetic, pharmaceutical or veterinary preparations; and foods, food supplements, cosmetic, pharmaceutical or veterinary preparations comprising such a composition. Finally, the present invention relates to specific stabilizers for the stabilisation of avenanthramide(s).

公开(公告)号：US20230118435A1

公开(公告)日：2023-04-20

申请号：US17909340

申请日：2021-03-05

Applicant: SYMRISE AG

Inventor： Sabine Lange ,  Martina Herrmann ,  Imke Meyer ,  Sebastian Bruncke ,  Holger Joppe ,  Kalpana Palani

IPC: A61K31/196 ,  A61K8/44 ,  A61Q19/10 ,  A61Q5/02

Abstract: The present invention relates generally to: a composition comprising or consisting of a specific avenanthramide and at least one penetration enhancer with an improved skin penetration; a method for preparing said composition; the use of such compositions as cosmetics or pharmaceuticals; and cosmetics or pharmaceuticals comprising said composition.

公开(公告)号：US09125936B2

公开(公告)日：2015-09-08

申请号：US14185157

申请日：2014-02-20

Applicant: Symrise AG

Inventor： Imke Meyer ,  Martina Herrmann ,  Dominik Stuhlmann ,  Holger Joppe

IPC: A61K36/9068 ,  A61K31/12 ,  A61K8/97 ,  A61K8/35 ,  A61Q19/00 ,  A61Q7/00 ,  A61Q19/08 ,  A61Q5/00 ,  A61Q5/12 ,  A61Q15/00 ,  A61Q19/02 ,  A61Q19/06

CPC classification number: A61K36/9068 ,  A61K8/35 ,  A61K8/97 ,  A61K31/12 ,  A61K2236/37 ,  A61K2236/39 ,  A61K2800/75 ,  A61Q5/006 ,  A61Q5/12 ,  A61Q7/00 ,  A61Q15/00 ,  A61Q19/00 ,  A61Q19/02 ,  A61Q19/06 ,  A61Q19/08 ,  A61K2300/00

Abstract: Ginger extract compositions containing 25 to 30% b.w. [6]-gingerol, 5 to 10% b.w. [8]-gingerol, 5 to 10% b.w. [10]-gingerol, 1.5 to 4% b.w. [6]-shogaol, 0.3 to 1.3% b.w. [8]-shogaol, 0.03 to 1% b.w. [10]-shogaol and 0.01 to 1% b.w. zingerone, with the amount of gingerols totaling 35 to 50% b.w. and the amount of shogaols totaling 1.5 to 6% b.w.

Abstract translation: 姜提取物组合物含25-30％b.w. [6] - 强啡灵，5〜10％b.w [8] - 强啡多，5至10％b.w. [10] - 烯草醇，1.5〜4％b.w。 [6] -shogaol，0.3〜1.3％b.w。 [8] -shogaol，0.03〜1％b.w。 [10] -shogaol和0.01至1％b.w。 姜油酮，姜油总量为35〜50％b.w。 和shogaols的总量为1.5到6％b.w.

公开(公告)号：US20140242020A1

公开(公告)日：2014-08-28

申请号：US14185157

申请日：2014-02-20

Applicant: Symrise AG

Inventor： Imke Meyer ,  Martina Herrmann ,  Dominik Stuhlmann ,  Holger Joppe

IPC: A61K36/9068 ,  A61Q19/00 ,  A61K8/35 ,  A61Q5/00 ,  A61K31/12 ,  A61K8/97

CPC classification number: A61K36/9068 ,  A61K8/35 ,  A61K8/97 ,  A61K31/12 ,  A61K2236/37 ,  A61K2236/39 ,  A61K2800/75 ,  A61Q5/006 ,  A61Q5/12 ,  A61Q7/00 ,  A61Q15/00 ,  A61Q19/00 ,  A61Q19/02 ,  A61Q19/06 ,  A61Q19/08 ,  A61K2300/00

Abstract: Suggested is a ginger extract, comprising (a) 25 to 30% b.w. [6]-gingerol (b) 5 to 10% b.w. [8]-gingerol (c) 5 to 10% b.w. [10]-gingerol (d) 1.5 to 4% b.w. [6]-shogaol (e) 0.3 to 1.3% b.w. [8]-shogaol; (f) 0.03 to 1% b.w. [10]-shogaol; (g) 0.01 to 1% b.w. zingerone, on condition that the amount of gingerols sums up to 35 to 50% b.w. and the amount of shogaols sums up to 1.5 to 6% b.w.

Abstract translation: 建议是姜提取物，包括（a）25-30％b.w. [6] - er烯醇（b）5〜10％b.w。 [8]庚烯酚（c）5至10％b.w。 [10]庚烯酚（d）1.5〜4％b.w。 [6] -shogaol（e）0.3〜1.3％b.w。 [8] -shogaol; （f）0.03〜1％b.w [10] -shogaol; （g）0.01至1％b.w。 姜黄酮，条件是姜醇含量达到35〜50％b.w。 并且shogaols的总量达到1.5到6％b.w.

公开(公告)号：US20200222730A1

公开(公告)日：2020-07-16

申请号：US16571882

申请日：2019-09-16

Applicant: SYMRISE AG

Inventor： Martina Herrmann ,  Holger Joppe ,  Paolo Pertile ,  Lorenzo Zanella

IPC: A61Q19/04 ,  A61Q7/02 ,  A61Q19/02 ,  A61Q7/00 ,  A61K8/9706

Abstract: The present invention relates to extracts of Isochrysis sp., preferably Tahitian Isochrysis, its cosmetic, dermatological and/or therapeutic uses and compositions and cosmetic, dermatological or therapeutic products comprising such an extract of Isochrysis sp., preferably Tahitian Isochrysis.

公开(公告)号：US09974721B2

公开(公告)日：2018-05-22

申请号：US15021489

申请日：2014-09-26

Applicant: Symrise AG

Inventor： Imke Meyer ,  Mirjam Knupfer ,  Holger Joppe ,  Antje Köhler ,  Bernd Hölscher ,  Marc Mansfeld

IPC: A61Q19/02 ,  A61K8/97 ,  A61K8/34 ,  A61Q5/00 ,  A61Q5/02 ,  A61Q5/08 ,  A61Q11/00 ,  A61Q15/00 ,  A61Q17/04 ,  A61Q19/00 ,  A61Q19/08 ,  A61Q5/06 ,  A61Q19/10

CPC classification number: A61K8/345 ,  A61K2800/92 ,  A61Q5/00 ,  A61Q5/02 ,  A61Q5/06 ,  A61Q5/08 ,  A61Q11/00 ,  A61Q15/00 ,  A61Q17/04 ,  A61Q19/00 ,  A61Q19/02 ,  A61Q19/08 ,  A61Q19/10

Abstract: Suggested is a composition comprising (a) larixol and at least one of the components (b1) to (b5) selected from (b1) tyrosinase inhibitors; (b2) sun protection factors; (b3) antioxidants; (b4) anti-inflammatory agents; and (b5) desquamating agents.

公开(公告)号：US20170112736A1

公开(公告)日：2017-04-27

申请号：US15021489

申请日：2014-09-26

Applicant: Symrise AG

Inventor： Imke Meyer ,  Mirjam Knupfer ,  Holger Joppe ,  Antje Köhler ,  Bernd Hölscher ,  Marc Mansfeld

IPC: A61K8/34 ,  A61Q19/00 ,  A61Q17/04 ,  A61Q11/00 ,  A61Q5/02 ,  A61Q5/00 ,  A61Q15/00 ,  A61Q5/08 ,  A61Q19/08

CPC classification number: A61K8/345 ,  A61K2800/92 ,  A61Q5/00 ,  A61Q5/02 ,  A61Q5/06 ,  A61Q5/08 ,  A61Q11/00 ,  A61Q15/00 ,  A61Q17/04 ,  A61Q19/00 ,  A61Q19/02 ,  A61Q19/08 ,  A61Q19/10

Abstract: Suggested is a composition comprising (a) larixol and at least one of the components (b1) to (b5) selected from (b1) tyrosinase inhibitors; (b2) sun protection factors; (b3) antioxidants; (b4) anti-inflammatory agents; and (b5) desquamating agents.

公开(公告)号：US20230124050A1

公开(公告)日：2023-04-20

申请号：US17909333

申请日：2020-03-18

Applicant: SYMRISE AG

Inventor： Martina Herrmann ,  Holger Joppe

IPC: A61K8/9794 ,  A61K36/899 ,  A61Q19/00 ,  A61K8/42 ,  A61K31/167 ,  A61K8/73 ,  A61K31/716 ,  A23L33/105

Abstract: The present invention relates generally to a composition or an oat extract comprising at least one avenanthramide compound or an analogue thereof and at least one β-glucan compound at predetermined ratios and having a low salt content. In addition, the present invention relates to a method for preparing such an oat extract, an oat extract obtained by said method, and the use of said composition or oat extract for the preparation of foods, food supplements, cosmetic, pharmaceutical or veterinary preparations. Finally, the present invention relates to foods, food supplements, cosmetics, pharmaceuticals or veterinary preparations comprising said composition or oat extract.

公开(公告)号：US12128257B2

公开(公告)日：2024-10-29

申请号：US16571882

申请日：2019-09-16

Applicant: SYMRISE AG

Inventor： Martina Herrmann ,  Holger Joppe ,  Paolo Pertile ,  Lorenzo Zanella

IPC: A61Q19/04 ,  A61K8/9706 ,  A61K8/9711 ,  A61K8/9789 ,  A61Q7/00 ,  A61Q7/02 ,  A61Q19/02

CPC classification number: A61Q19/04 ,  A61K8/9706 ,  A61K8/9711 ,  A61K8/9789 ,  A61Q7/00 ,  A61Q7/02 ,  A61Q19/02

Abstract: The present invention relates to extracts of Isochrysis sp., preferably Tahitian Isochrysis, its cosmetic, dermatological and/or therapeutic uses and compositions and cosmetic, dermatological or therapeutic products comprising such an extract of Isochrysis sp., preferably Tahitian Isochrysis.

公开(公告)号：US20230118467A1

公开(公告)日：2023-04-20

申请号：US17909693

申请日：2020-03-06

Applicant: SYMRISE AG

Inventor： Martina Herrmann ,  Gerhard Schmaus ,  Nikolas Bugdahn ,  Dominik Stuhlmann ,  Katharina Striewe ,  Holger Joppe

IPC: A61K8/42 ,  A61K8/9794 ,  A61Q19/00 ,  A61Q19/02 ,  A61Q3/00 ,  A61Q5/00 ,  A61K31/164 ,  A61K36/899 ,  A23L33/105

Abstract: The present invention relates generally to: the cosmetic or pharmaceutical use of avenanthramide L or an oat extract comprising avenanthramide L; avenanthramide L or an oat extract comprising avenanthramide L as a neurokinin-1 receptor NK1R antagonist; and a method for preparing of preparing avenalumic acid and/or avenanthramide L.