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    Injectable hydrogel with an enhanced remanence and with an enhanced ability to create volume
    7.
    发明授权
    Injectable hydrogel with an enhanced remanence and with an enhanced ability to create volume 有权
    可注射的水凝胶具有增强的剩磁性和增强的创造体积的能力

    公开(公告)号：US08574629B2

    公开(公告)日：2013-11-05

    申请号：US12512581

    申请日：2009-07-30

    申请人： Samuel Gavard Molliard

    发明人： Samuel Gavard Molliard

    IPC分类号： A61K8/64 ,  A61L9/14 ,  A61K8/73

    CPC分类号： A61L27/52 ,  A61L27/20 ,  C08L5/08

    摘要： An injectable hydrogel includes a hydrogel matrix based on (a) single-phase-type cross-linked biopolymer(s), characterized in that previously cross-linked biopolymer hydrogel particles are co-cross-linked with the matrix. A method of and a process for production of the above-mentioned hydrogel are also disclosed.

    摘要翻译： 可注射水凝胶包括基于（a）单相型交联生物聚合物的水凝胶基质，其特征在于先前交联的生物聚合物水凝胶颗粒与基质共交联。 还公开了上述水凝胶的制造方法和制造方法。

    INJECTABLE HYDROGEL FOR THE LONG-TERM SUPPLEMENTATION OF GLYCEROL IN THE SKIN
    8.
    发明申请
    INJECTABLE HYDROGEL FOR THE LONG-TERM SUPPLEMENTATION OF GLYCEROL IN THE SKIN 有权
    用于长期补充皮肤中的甘油的注射用水

    公开(公告)号：US20120108674A1

    公开(公告)日：2012-05-03

    申请号：US13322240

    申请日：2010-05-14

    申请人： Samuel Gavard Molliard ,  Cyrille Vinchon

    发明人： Samuel Gavard Molliard ,  Cyrille Vinchon

    IPC分类号： A61K31/047 ,  A61P17/02 ,  A61Q19/08 ,  A61K8/34

    CPC分类号： A61L27/52 ,  A61K8/042 ,  A61K8/735 ,  A61K2800/91 ,  A61L27/20 ,  A61L2400/06 ,  A61Q19/08 ,  C08L5/08

    摘要： An injectable hydrogel, includes, in weight, in a physiologically acceptable carrier fluid: 0.01 to 5% of glycerol and 0.1 to 5% of cross-linked hyaluronic acid, or one of the salts thereof; characterized in that the hyaluronic acid or one of the salts thereof is cross-linked by the formation of covalent bonds using bifunctional or polyfunctional molecules, the injectable hydrogel being sterilized in moist heat and having viscoelastic properties such that Tanδ at a frequency of 1 Hz is less than or equal to 1.10. A method for producing the hydrogel, to a kit containing the hydrogel, as well as to the use thereof in dermatology are also described.

    摘要翻译： 注射用水凝胶重量含有生理上可接受的载体液：0.01〜5％的甘油和0.1〜5％的交联透明质酸，或其盐之一; 其特征在于，所述透明质酸或其盐之一通过使用双功能或多官能分子形成共价键而交联，所述可注射水凝胶在湿热下进行灭菌并具有粘弹性，使得频率为1Hz的Tanδ为 小于或等于1.10。 还描述了制备水凝胶的方法，含有水凝胶的试剂盒及其在皮肤病学中的用途。