Abstract:
Disclosed are films and a packaging for gas or vapor decontaminable packaging applications and a method for creating a sterile packaging using the same. These films are particularly useful for sterile storage and transport of objects for medical, pharmaceutical or cosmetic uses, in particular of sterile pharmaceutical primary packaging means, like vials, ampules, syringes, or cartridges. Said film comprises at least a layer of a selectively permeable non-woven, a layer of a punctured film, and an adhesive which can be activated by energy transmission. Optionally it comprises further film layers. The method for creating a sterile packaging comprises the step of hermetically closing the packaging by activating the adhesive thereby making the non-woven impermeable.
Abstract:
Disclosed is a process for the treatment or processing of containers that serve for storing, or contain, substances for medical, pharmaceutical or cosmetic applications, wherein the containers are conveyed automatically, by a conveyor, past at least one processing station or pass it for the treatment or processing. In the process, a plurality of containers is conveyed by the conveyor while being held by a carrier in a regular arrangement. The containers held on the carrier are raised to a raised position for the treatment or processing at or in the respective processing station and are lowered after the treatment or processing, to be held again on the carrier in the regular arrangement. The carrier is configured such that the containers can be held on the carrier during the entire process. A negative pressure acts on the bottoms of the containers in order to lower them.
Abstract:
A holding structure for concurrently holding a plurality of containers for substances for cosmetic, medical or pharmaceutical applications, in particular of vials, is provided. The holder includes a carrier having a plurality of apertures or receptacles into which the containers can be inserted and holding means for holding the containers in the apertures or receptacles. The holding means has at least two holding tabs, which are provided at the edge of a respective aperture or receptacle and protrude from an upper side of the carrier for holding the respective container. The holding tabs are resiliently pivoted or folded back as the containers are inserted into the apertures or receptacles and so that the holding tabs are matched to the containers such that these are held by the holding tabs with a radial clearance and low tension.
Abstract:
In a process and apparatus for treating or processing containers (2) that are used for storing substances for medical, pharmaceutical or cosmetic applications or contain the same, cylindrical containers open at least at one end are automatically led past or pass through processing stations for treatment or processing by means of a conveying device, while said containers are jointly held by a carrier (25; 134) in a regular two-dimensional arrangement. The carrier comprises a plurality of openings or receptacles (32; 39; 87; 120), which determine the regular arrangement.According to the invention, the treatment or processing of the containers is performed on or in at least one of the processing stations while the containers are supported by the carrier. This opens up new possibilities for treating or processing the containers, for example when crimping metal lids or during freeze-drying.
Abstract:
A method of filling pharmaceutical containers includes: filling a first plurality of containers, the first plurality of containers being supported by a first holder supported on a first step of a first transport and packaging container defining a first step height, the filling includes moving filling needles of a filling device to a filling needle height and dispensing a substance into each of the first plurality of containers; and filling a second plurality of containers, the second plurality of containers being supported by a second holder supported on a second step of a second transport and packaging container defining a second step height equal to the first step height, the filling includes moving the filling needles to the filling needle height and dispensing the substance into each of the second plurality of containers, the second plurality of containers differ from the first plurality of containers in at least one aspect.
Abstract:
A container holding device for holding one or more containers includes: a base plate having an upper surface, a bottom surface, and one or more holes each extending from the upper surface to the bottom surface and having a central symmetry axis Laxis orthogonal to the base plate; and two or more holding elements that are located around each hole beneath the bottom surface of the base plate. The holding elements are configured to: contact an outer surface of a container that is placed into the container holding device at a bottom edge of a top region of the container, such that the container hangs in the container holding device in a first position p1 in which the holding elements do not exert any force on the outer surface of the container that is radial; and contact the outer surface of the container in a shoulder region.
Abstract:
Disclosed is a method for packaging a plurality of containers for substances for medical, pharmaceutical or cosmetic applications in a packaging structure. The structure has a box-shaped upper part and a box-shaped lower part, forming a box-shaped receptacle in which the containers are accommodated. The plurality of containers are disposed directly on the bottom of the lower part that the containers are supported vertically on the bottom of the lower part, and the upper part is put onto the upper ends of the containers. The positions of the containers on the lower part are secured using side walls that project vertically from the bottom of the lower part and/or of the upper part, and the upper part and/or the lower part is configured and provided in a way that the containers are in direct contact with each other in the box-shaped receptacle and cannot be displaced relative to each other.
Abstract:
A supporting structure for concurrently supporting a plurality of vials is provided. The supporting structure includes a carrier having apertures or receptacles, into which the vials can be inserted to be supported therein on the carrier. The vials have a bottom that forms a base, a cylindrical side wall, and an annular transition region between the base and the cylindrical side wall. The carrier has a retaining protrusion at a lower end of the aperture or receptacle that extends into the respective aperture or receptacle inward in radial direction. The retaining protrusion supports the vial in cooperation with the transition region outside the base in such a manner that the bottoms or bases of the vials jut out of the apertures or receptacles of the carrier and are freely accessible from the lower side of the carrier.
Abstract:
A method for sterile packaging of a plurality of containers is provided that includes: providing a carrier in which a plurality of receptacles are formed, the receptacles being formed by a closed bottom and a circumferential side wall, the upper ends of the receptacles, which are opposite to the respective bottom, are open and circumferential connecting webs are provided at the upper ends; placing the containers in the receptacles; providing a gas-impermeable protective foil; bonding the protective foil along the connecting webs with the upper surface of the carrier to package all the receptacles with the containers accommodated individually therein; and sterilizing the receptacles with the containers accommodated therein and/or the inner volumes of the containers by a gas flowing into the receptacles and/or into the inner volumes of the containers through at least one gas-permeable portion.
Abstract:
Disclosed is a supporting structure for concurrently supporting a plurality of containers for substances for medical, pharmaceutical or cosmetic applications, comprising a flat, rectangular-shaped carrier having a plurality of apertures or receptacles and at least one supporting member, which is releasably coupled to the carrier, wherein the respective supporting member is configured to support a plurality of containers to said carrier by a positive-fit.According to the invention the positive-fit is formed by coupling the respective supporting member with the carrier such that the containers supported on the container extend into the apertures or receptacles of the carrier.By means of the supporting members tolerances, in particular with respect to the outer radius or the outer contour of the containers and to their length, can be compensated for in a simple manner. Because the containers extend through the apertures of the carrier, the bottoms of the containers are freely accessible from the underside of the carrier even if these are supported on the carrier. This offers significant advantages when processing or further processing the containers. Since the supporting means are clipped into the carrier, these are retained to the carrier in axial direction and thus are supported very reliably on the carrier.