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公开(公告)号：US08096297B2
公开(公告)日：2012-01-17
申请号：US12702596
申请日：2010-02-09
CPC分类号： A61B5/029 , A61B5/0836 , A61M16/0045 , A61M16/0833 , A61M2016/0036 , A61M2230/432 , G01N33/004 , Y02A50/243
摘要： Apparatus and methods for non-invasively determining cardiac output using partial re-breathing techniques are disclosed in which the apparatus is constructed with an instantaneously adjustable deadspace for accommodating differences in breathing capacities of various patients. The apparatus is constructed of inexpensive elements, including a single two-way valve which renders the apparatus very simple to use and inexpensive so that the unit may be readily disposable. The method of the invention provides a novel means of estimating cardiac output based on alveolar CO2 values rather than end-tidal CO2 values as previously practiced. A program for calculating cardiac output is also disclosed.
摘要翻译： 公开了使用部分再呼吸技术非侵入性地确定心输出量的装置和方法，其中该装置构造有瞬时可调的死区，以适应各种患者的呼吸能力差异。 该设备由便宜的元件构成，包括单个双向阀，其使得该设备使用起来非常简单且便宜，使得该单元可以容易地被一次性使用。 本发明的方法提供了一种基于肺泡二氧化碳值估计心输出量的新方法，而不是如先前所述的潮汐CO 2值。 还公开了一种用于计算心输出量的程序。
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2.发明授权Portable pressure transducer, pneumotach for use therewith, and associated methods 有权便携式压力传感器，与其一起使用的气动换向器及相关方法公开(公告)号：US07654146B2
公开(公告)日：2010-02-02
申请号：US11705561
申请日：2007-02-12
申请人： Joseph A. Orr , Scott A. Kofoed , Kevin Durst
发明人： Joseph A. Orr , Scott A. Kofoed , Kevin Durst
IPC分类号： G01L7/00
摘要： A system for sensing respiratory pressure includes a portable pressure transducer configured to be carried by or proximate to a respiratory conduit, such as a breathing circuit or a nasal canula. The portable pressure transducer may removably couple with a pneumotach, in the form of an airway adapter, disposed along the respiratory conduit. The pneumotach may include two pressure ports positioned at opposite sides of an obstruction, which partially blocks flow through a primary conduit of the pneumotach. Corresponding sample conduits of the portable pressure transducer removably couple with the pressure ports. The pressure ports may have sealing elements which are configured to seal against piercing members of the sample conduits upon introduction of the piercing members therethrough. Upon removal of the piercing members, the sealing elements substantially reseal. Methods for using the system are also disclosed.
摘要翻译： 用于感测呼吸压力的系统包括便携式压力传感器，其配置为由呼吸管道（例如呼吸回路或鼻腔）携带或接近呼吸管道。 便携式压力传感器可以可移除地与沿着呼吸导管布置的呼吸道适配器形式的呼吸器联接。 冲击器可以包括位于障碍物的相对侧的两个压力端口，其部分地阻塞通过冲击器的主导管的流动。 便携式压力传感器的相应样品管路与压力端口可拆卸地联接。 压力端口可以具有密封元件，其被构造成在引入刺穿构件通过其时密封样品导管的刺穿构件。 在移除穿孔构件时，密封元件基本上重新密封。 还公开了使用该系统的方法。
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3.发明授权Portable pressure transducer, pneumotach for use therewith, and associated methods 有权便携式压力传感器，与其一起使用的气动换向器及相关方法公开(公告)号：US06968741B2
公开(公告)日：2005-11-29
申请号：US10729404
申请日：2003-12-05
申请人： Joseph A. Orr , Scott A. Kofoed , Kevin Durst
发明人： Joseph A. Orr , Scott A. Kofoed , Kevin Durst
摘要： A system for sensing respiratory pressure includes a portable pressure transducer configured to be carried by or proximate to a respiratory conduit, such as a breathing circuit or a nasal canula. The portable pressure transducer may removably couple with a pneumotach, in the form of an airway adapter, disposed along the respiratory conduit. The pneumotach may include two pressure ports positioned at opposite sides of an obstruction, which partially blocks flow through a primary conduit of the pneumotach. Corresponding sample conduits of the portable pressure transducer removably couple with the pressure ports. The pressure ports may have sealing elements which are configured to seal against piercing members of the sample conduits upon introduction of the piercing members therethrough. Upon removal of the piercing members, the sealing elements substantially reseal. Methods for using the system are also disclosed.
摘要翻译： 用于感测呼吸压力的系统包括便携式压力传感器，该便携式压力传感器被配置为由呼吸管道（例如呼吸回路或鼻腔）携带或接近呼吸管道。 便携式压力传感器可以可移除地与沿着呼吸导管布置的呼吸道适配器形式的呼吸器联接。 冲击器可以包括位于障碍物的相对侧的两个压力端口，其部分地阻塞通过冲击器的主导管的流动。 便携式压力传感器的相应样品管路与压力端口可拆卸地联接。 压力端口可以具有密封元件，其被构造成在引入刺穿构件通过其时密封样品导管的刺穿构件。 在移除穿孔构件时，密封元件基本上重新密封。 还公开了使用该系统的方法。
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公开(公告)号：US07686012B2
公开(公告)日：2010-03-30
申请号：US11120103
申请日：2005-05-02
CPC分类号： A61B5/029 , A61B5/0836 , A61M16/0045 , A61M16/0833 , A61M2016/0036 , A61M2230/432 , G01N33/004 , Y02A50/243
摘要： Apparatus and methods for non-invasively determining cardiac output using partial re-breathing techniques are disclosed in which the apparatus is constructed with an instantaneously adjustable deadspace for accommodating differences in breathing capacities of various patients. The apparatus is constructed of inexpensive elements, including a single two-way valve which renders the apparatus very simple to use and inexpensive so that the unit may be readily disposable. The method of the invention provides a novel means of estimating cardiac output based on alveolar CO2 values rather than end-tidal CO2 values as previously practiced. A program for calculating cardiac output is also disclosed.
摘要翻译： 公开了使用部分再呼吸技术非侵入性地确定心输出量的装置和方法，其中该装置构造有瞬时可调的死区，以适应各种患者的呼吸能力差异。 该设备由便宜的元件构成，包括单个双向阀，其使得该设备使用起来非常简单且便宜，使得该单元可以容易地被一次性使用。 本发明的方法提供了一种基于肺泡二氧化碳值估计心输出量的新方法，而不是如先前所述的潮汐CO 2值。 还公开了一种用于计算心输出量的程序。
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公开(公告)号：US07335164B2
公开(公告)日：2008-02-26
申请号：US09841451
申请日：2001-04-24
申请人： Leslie E. Mace , Lawrence L. Labuda , Perry R. Blazewicz , David R. Rich , Michael B. Jaffe , Joseph A. Orr , Scott A. Kofoed
发明人： Leslie E. Mace , Lawrence L. Labuda , Perry R. Blazewicz , David R. Rich , Michael B. Jaffe , Joseph A. Orr , Scott A. Kofoed
CPC分类号： G01N21/6428 , A61B5/083 , A61B5/0833 , A61B5/087 , A61B5/097 , G01F1/40 , G01F1/42 , G01N21/0303 , G01N21/05 , G01N21/3504 , G01N21/645 , G01N33/0036 , G01N33/497 , G01N2001/2244 , G01N2021/6432
摘要： An integrated airway adapter capable of monitoring any combination of respiratory flow, O2 concentration, and concentrations of one or more of CO2, N2O, and an anesthetic agent in real time, breath by breath. Respiratory flow may be monitored with differential pressure flow meters under diverse inlet conditions through improved sensor configurations which minimize phase lag and dead space within the airway. Molecular oxygen concentration may be monitored by way of luminescence quenching techniques. Infrared absorption techniques may be used to monitor one or more of CO2, N2O, and anesthetic agents.
摘要翻译： 能够监测呼吸流量O 2浓度的任何组合以及CO 2 2 N 2 N 2 N 2中的一种或多种的浓度的组合气道适配器， O和麻醉剂实时呼吸。 可以通过改进的传感器配置在不同入口条件下通过差压流量计监测呼吸流量，从而最小化气道内的相位滞后和死区。 可以通过发光淬灭技术监测分子氧浓度。 红外吸收技术可用于监测一种或多种CO 2，N 2 O和麻醉剂。
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公开(公告)号：US5535633A
公开(公告)日：1996-07-16
申请号：US287665
申请日：1994-08-09
申请人： Scott A. Kofoed , Joseph A. Orr
发明人： Scott A. Kofoed , Joseph A. Orr
摘要： A differential pressure sensor for measuring respiratory gas flow including a tubular housing having a bore containing a diametrically-oriented, longitudinally extending strut containing first and second lumens having longitudinally spaced pressure ports at axially spaced locations of the strut, the ports being located on opposite sides of a bore restriction.
摘要翻译： 一种用于测量呼吸气流的差压传感器，包括管状壳体，所述管状壳体具有包含径向定向的纵向延伸的支柱的孔，所述支柱包含第一和第二腔，所述第一和第二腔在所述支柱的轴向间隔开的位置处具有纵向隔开的压力端口，所述端口位于相对侧 的钻孔限制。
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公开(公告)号：US06475158B1
公开(公告)日：2002-11-05
申请号：US09694954
申请日：2000-10-24
申请人： Joseph A. Orr , Scott A. Kofoed , Kevin Durst
发明人： Joseph A. Orr , Scott A. Kofoed , Kevin Durst
IPC分类号： A61B508
CPC分类号： A61B5/024 , A61B5/0002 , A61B5/0833 , A61B5/087
摘要： A calorimeter configured to determine a metabolic rate of an individual based on measurements of the individual's respiration. The calorimeter includes an inlet, a flow sensor, a mixing chamber, a gas sensor, and a calibrator. Each of these elements is located along a flow path through the calorimeter. The calibrator of the calorimeter includes a fan that is configured to force calibration gases, such as room air, through or past the gas sensor. A cardiac rate monitor is associated with a processor of the calorimeter. The processor is configured to substantially simultaneously determine and establish a relationship between the cardiac rate of the individual and the measured respiratory parameters or the metabolic rate of the individual. Data representative of this relationship may be communicated to a processor or memory of a portable calorimeter to be subsequently used by the individual. The portable calorimeter, which can be worn by the individual, includes a cardiac rate monitor that measures the cardiac rate of the individual and communicates data representative of the individual's cardiac rate to the processor, which then determines the metabolic rate of the individual based on relationship data obtained from the respiratory-based calorimeter. Methods of calibrating and using the calorimeters are also disclosed.
摘要翻译： 配置成基于个体呼吸的测量来确定个体的代谢率的量热计。 量热计包括入口，流量传感器，混合室，气体传感器和校准器。 这些元件中的每一个沿着通过热量计的流动路径定位。 量热计的校准器包括被配置为迫使校准气体（例如室内空气）通过或经过气体传感器的风扇。 心率监测器与量热计的处理器相关联。 处理器被配置为基本上同时确定和建立个体的心率和测量的呼吸参数或个体的代谢率之间的关系。 表示该关系的数据可以传送到随后由个人使用的便携式量热计的处理器或存储器。 便携式量热计可以由个人佩戴，包括心率监测器，其测量个体的心率，并将表示个体心率的数据传达给处理器，然后处理器基于关系确定个体的代谢率 从呼吸型量热仪获得的数据。 还公开了校准和使用热量计的方法。
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公开(公告)号：USD423101S
公开(公告)日：2000-04-18
申请号：US102863
申请日：1999-04-02
申请人： Kevin Durst , Scott A. Kofoed , Joseph A. Orr
设计人： Kevin Durst , Scott A. Kofoed , Joseph A. Orr
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公开(公告)号：US5789660A
公开(公告)日：1998-08-04
申请号：US680492
申请日：1996-07-15
申请人： Scott A. Kofoed , Joseph A. Orr , David R. Rich
发明人： Scott A. Kofoed , Joseph A. Orr , David R. Rich
摘要： An integrated airway adapter capable of monitoring CO.sub.2 concentration in real time, breath by breath using infrared absorption techniques and monitoring respiratory flow with differential pressure flowmeters under diverse inlet conditions through improved sensor configurations which minimize phase lag and dead space within the airway adapter.
摘要翻译： 一种集成气道适配器，能够实时监测二氧化碳浓度，使用红外吸收技术进行呼吸呼吸，并通过改进的传感器配置在不同入口条件下通过差压流量计监测呼吸流量，从而最大限度地减少气道适配器内的相位滞后和死区。
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公开(公告)号：US07018340B2
公开(公告)日：2006-03-28
申请号：US10657577
申请日：2003-09-08
IPC分类号： A61B5/00
CPC分类号： A61B5/029 , A61B5/0836 , A61M16/0045 , A61M16/0833 , A61M2016/0036 , A61M2230/432 , G01N33/004 , Y02A50/243
摘要： Apparatus and methods for non-invasively determining the cardiac output or pulmonary capillary blood flow of a patient using partial re-breathing techniques. The apparatus includes a substantially instantaneously adjustable deadspace volume for accommodating differences in sizes or breathing capacities of various patients. The apparatus may be constructed of inexpensive elements, including one or more two-way valves, which render the apparatus very simple to use and inexpensive so that the unit may be employed as a disposable product. The method of the invention includes estimating the cardiac output or pulmonary capillary blood flow of a patient based on partial pressure of alveolar CO2, rather than on the partial pressure of end tidal CO2, as previously practiced. A computer program for calculating the cardiac output or pulmonary capillary blood flow of a patient is also disclosed.
摘要翻译： 使用部分再呼吸技术非侵入性地确定患者的心输出量或肺毛细血管血流量的装置和方法。 该装置包括基本上即时可调的死空间体积，用于适应各种患者的尺寸或呼吸能力的差异。 该设备可以由廉价的元件构成，包括一个或多个双向阀，这使得该设备使用起来非常简单并且便宜，使得该单元可以用作一次性产品。 本发明的方法包括基于肺泡CO 2 2的分压来估计患者的心输出量或肺毛细血管血流量，而不是基于潮气CO 2 2的分压， SUB>，如前所述。 还公开了一种用于计算患者的心输出量或肺毛细血管血流量的计算机程序。
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