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公开(公告)号：US09138338B2
公开(公告)日：2015-09-22
申请号：US13322091
申请日：2010-05-21
CPC分类号： A61F2/95 , A61F2/958 , A61F2002/9522 , Y10T29/49908
摘要： A two-stage method of compressing a stent entails providing an expandable stent (100,105) in a radially expanded state. An outward pressure is applied to an inner surface of the tubular framework to support the stent, and a diameter of the stent is reduced to a first compressed diameter (D1) while applying the outward pressure. The outward pressure is halted after reaching the first compressed diameter. According to an embodiment in which the stent is balloon-expandable, a delivery balloon catheter (130) comprising an uninflated balloon in a delivery configuration is inserted into the lumen after halting the outward pressure. The diameter of the stent is reduced to a second compressed diameter (D2) smaller than the first compressed diameter to crimp the stent onto the delivery balloon catheter.
摘要翻译： 压缩支架的两级方法需要提供处于放大状态的可扩张支架（100,105）。 向管状框架的内表面施加向外的压力以支撑支架，并且在施加向外的压力的同时将支架的直径减小到第一压缩直径（D1）。 达到第一压缩直径后，向外的压力停止。 根据其中支架是球囊可膨胀的实施例，包括具有输送构型的未膨胀气囊的输送气囊导管（130）在停止向外的压力之后插入腔内。 支架的直径减小到小于第一压缩直径的第二压缩直径（D2），以将支架卷曲到输送球囊导管上。
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公开(公告)号：US20120060348A1
公开(公告)日：2012-03-15
申请号：US13322091
申请日：2010-05-21
IPC分类号： B23P11/00
CPC分类号： A61F2/95 , A61F2/958 , A61F2002/9522 , Y10T29/49908
摘要： A two-stage method of compressing a stent entails providing an expandable stent (100,105) in a radially expanded state. An outward pressure is applied to an inner surface of the tubular framework to support the stent, and a diameter of the stent is reduced to a first compressed diameter (D1) while applying the outward pressure. The outward pressure is halted after reaching the first compressed diameter. According to an embodiment in which the stent is balloon-expandable, a delivery balloon catheter (130) comprising an uninflated balloon in a delivery configuration is inserted into the lumen after halting the outward pressure. The diameter of the stent is reduced to a second compressed diameter (D2) smaller than the first compressed diameter to crimp the stent onto the delivery balloon catheter.
摘要翻译： 压缩支架的两级方法需要提供处于放大状态的可扩张支架（100,105）。 向管状框架的内表面施加向外的压力以支撑支架，并且在施加向外的压力的同时将支架的直径减小到第一压缩直径（D1）。 达到第一压缩直径后，向外的压力停止。 根据其中支架是球囊可膨胀的实施例，包括具有输送构型的未膨胀气囊的输送气囊导管（130）在停止向外的压力之后插入腔内。 支架的直径减小到小于第一压缩直径的第二压缩直径（D2），以将支架卷曲到输送球囊导管上。
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公开(公告)号：US09163333B2
公开(公告)日：2015-10-20
申请号：US13548956
申请日：2012-07-13
CPC分类号： A61L31/041 , A61F2/07 , B29C47/0014 , B29C47/0064 , B29C47/06 , B29K2075/00 , B29K2083/00 , B29L2009/00 , B29L2023/20 , B29L2031/7546 , B32B2250/03 , D01D5/0038 , D01D5/0069 , D01D5/0084 , D04H1/728 , D04H3/073
摘要： A method for making a graft layer is provided. The graft layer has at least two layers with different porosities. The two layers are applied by electrospinning. The parameters of the electrospinning may be varied when applying the first and second layers in order to achieve different porosities of the first and second layers.
摘要翻译： 提供了制备接枝层的方法。 接枝层具有至少两层具有不同孔隙率的层。 通过静电纺丝应用两层。 当施加第一和第二层以便实现第一和第二层的不同孔隙率时，静电纺丝的参数可以变化。
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公开(公告)号：US20130018220A1
公开(公告)日：2013-01-17
申请号：US13548956
申请日：2012-07-13
IPC分类号： A61F2/06
CPC分类号： A61L31/041 , A61F2/07 , B29C47/0014 , B29C47/0064 , B29C47/06 , B29K2075/00 , B29K2083/00 , B29L2009/00 , B29L2023/20 , B29L2031/7546 , B32B2250/03 , D01D5/0038 , D01D5/0069 , D01D5/0084 , D04H1/728 , D04H3/073
摘要： A method for making a graft layer is provided. The graft layer has at least two layers with different porosities. The two layers are applied by electrospinning. The parameters of the electrospinning may be varied when applying the first and second layers in order to achieve different porosities of the first and second layers.
摘要翻译： 提供了制备接枝层的方法。 接枝层具有至少两层具有不同孔隙率的层。 通过静电纺丝应用两层。 当施加第一和第二层以便实现第一和第二层的不同孔隙率时，静电纺丝的参数可以变化。
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公开(公告)号：US20240058094A1
公开(公告)日：2024-02-22
申请号：US18234440
申请日：2023-08-16
申请人： Ram H. Paul, Jr. , Sean D. Chambers , David Gross , Neal Fearnot , Jesse Roll , Joshua F. Krieger , Carl A. Cook
发明人： Ram H. Paul, Jr. , Sean D. Chambers , David Gross , Neal Fearnot , Jesse Roll , Joshua F. Krieger , Carl A. Cook
CPC分类号： A61B90/39 , A61B5/055 , A61L31/022 , A61L31/14 , A61B2090/3954 , A61M2025/09075
摘要： The disclosure relates to methods of imaging a portion of a body vessel using magnetic resonance imaging (MRI), methods of performing interventional medical treatment under MRI, interventional medical devices, such as wire guides, useful in performing treatment under MRI, and methods of making interventional medical devices. A method of imaging a portion of a body vessel of a patient using MRI includes advancing through a body vessel an end of a wire guide comprising a continuous metal core member and a continuous jacket disposed over the entire core member through a body vessel and scanning the portion of the patient that is positioned within an MRI scanner and that includes a portion of the body vessel within which the end of the wire guide is disposed. A secondary medical device, such as a catheter, can be disposed over the wire guide and manipulated in the method.
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6.发明授权公开(公告)号：US08881365B2
公开(公告)日：2014-11-11
申请号：US13457949
申请日：2012-04-27
CPC分类号： A61F2/07 , A61F2/89 , A61F2002/065 , A61F2002/075 , A61F2250/0067 , Y10T29/49849
摘要： An implantable graft device having treated yarn is disclosed. The device comprises a graft body forming a lumen defining a longitudinal axis and comprising proximal and distal ends. The graft body comprises a woven fabric having warp yarns aligned in a first direction and a weft yarns aligned in a second direction. At least one of the weft yarns and the warp yarns has an agent applied thereto defining treated yarns of the graft body.
摘要翻译： 公开了一种具有经处理的纱线的可植入移植装置。 该装置包括形成限定纵向轴线并包括近端和远端的内腔的移植物主体。 移植物主体包括具有沿第一方向排列的经纱和沿第二方向排列的纬纱的机织织物。 纬纱和经纱中的至少一个具有施加到其上的试剂，其限定了移植物体的经处理的纱线。
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公开(公告)号：US08870816B2
公开(公告)日：2014-10-28
申请号：US13130420
申请日：2008-12-01
申请人： Sean D. Chambers , Steen Aggerholm , Joe Horn
发明人： Sean D. Chambers , Steen Aggerholm , Joe Horn
IPC分类号： A61M31/00 , A61M37/00 , A61B17/22 , A61B17/32 , A61D1/02 , A61M25/10 , A61B17/3207 , A61B17/00 , A61M25/00
CPC分类号： A61M25/104 , A61B17/320725 , A61B2017/00539 , A61B2017/00778 , A61B2017/22061 , A61M2025/0057 , A61M2025/1013 , A61M2025/105 , A61M2025/1061 , A61M2025/1086 , A61M2025/109
摘要： A balloon catheter is provided that may be used to dilate hardened regions of a stenosis on a vessel wall. The balloon catheter is provided with cutting elements that extend along a surface of a balloon. At least one bioactive is present, either on the cutting element, within the interior of the balloon, within the material of the balloon or on an outside surface of the balloon. The bioactive is delivered to the vessel wall upon dilation of the balloon.
摘要翻译： 提供了可用于扩张血管壁上的狭窄硬化区域的球囊导管。 气囊导管设置有沿气球表面延伸的切割元件。 在切割元件上，在球囊的内部，气囊的材料内或气球的外表面上存在至少一种生物活性物质。 气球膨胀后，生物活性物质被传送到血管壁。
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公开(公告)号：US20130079867A1
公开(公告)日：2013-03-28
申请号：US13681362
申请日：2012-11-19
申请人： Grant T. Hoffman , Sean D. Chambers , Ram H. Paul
发明人： Grant T. Hoffman , Sean D. Chambers , Ram H. Paul
IPC分类号： A61F2/24
CPC分类号： A61F2/2475 , A61F2/24 , A61F2/2418 , A61F2220/0008 , A61F2220/0016 , A61F2220/005 , A61F2220/0058
摘要： The disclosure relates to support frames for prosthetic implantable valves. The support frames may include a plurality of symmetrically arrayed interconnected U-shaped member structures. Preferred support frames are tubular structures enclosing a longitudinal axis and including a plurality of U-shaped member structures facing a distal or a proximal end of the support frame. Each U-shaped member structure may be connected to a single longitudinally adjacent U-shaped member facing in an opposite longitudinal direction, as well as two laterally adjacent U-shaped members.
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公开(公告)号：US08372140B2
公开(公告)日：2013-02-12
申请号：US12683670
申请日：2010-01-07
IPC分类号： A61F2/06
CPC分类号： A61F2/2412 , A61F2/2418 , A61F2/2475 , A61F2210/0076 , A61F2220/0016 , A61F2220/005 , A61F2220/0058 , A61F2220/0075 , A61F2230/0054
摘要： An implantable valve prosthesis is provided. The valve prosthesis includes a frame structure having first and second independent frame elements. A graft member is attached to both the first and second frame elements and includes a closure member, such as a valve leaflet. The closure member is movable between a first position that allows fluid flow through the prosthesis in a first, antegrade direction and a second position that restricts flow through the prosthesis in a second, retrograde direction.
摘要翻译： 提供可植入瓣膜假体。 瓣膜假体包括具有第一和第二独立框架元件的框架结构。 移植构件附接到第一和第二框架元件两者并且包括封闭构件，例如瓣膜单元。 闭合构件可在第一位置和第二位置之间移动，所述第一位置允许流体以第一顺行方向流过假体，而第二位置限制在第二逆行方向上流过假体的流动。
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公开(公告)号：US08128686B2
公开(公告)日：2012-03-06
申请号：US12425911
申请日：2009-04-17
申请人： Ram H. Paul, Jr. , Sean D. Chambers
发明人： Ram H. Paul, Jr. , Sean D. Chambers
IPC分类号： A61F2/06
CPC分类号： A61F2/86 , A61F2/2418 , A61F2/2475 , A61F2/856 , A61F2/954 , A61F2002/061 , A61F2002/065 , A61F2002/075 , A61F2002/825 , A61F2002/9505 , A61F2002/9511 , A61F2220/0016 , A61F2220/005 , A61F2220/0058 , A61F2220/0075 , A61F2230/0054
摘要： The present disclosure describes an implantable branched vessel prosthesis, such as a prosthetic valve, having both a radially expandable annular portion and a laterally extendable branch portion. Methods of delivering the branched vessel prosthesis to a branched body vessel are also provided, as well as delivery systems comprising the branched vessel prosthesis. The branched vessel prostheses are useful, for example, as implantable prosthetic venous valves for treating venous valve insufficiency. The delivery system is configured to deploy independently both the annular portion within a primary vessel and the branch portion within a branch vessel with only one delivery system.
摘要翻译： 本公开描述了一种可植入的分支血管假体，例如假体瓣膜，其具有径向可扩张的环形部分和可横向延伸的分支部分。 还提供将分支血管假体递送到分支体血管的方法，以及包括分支血管假体的递送系统。 分支血管假体可用作例如用于治疗静脉瓣膜功能不全的可植入假体静脉瓣。 输送系统被配置为仅在一个主容器内部的环形部分和仅具有一个输送系统的分支容器内的分支部分。
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