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公开(公告)号：US20220145328A1
公开(公告)日：2022-05-12
申请号：US17390777
申请日：2021-07-30
发明人： Kenneth Prentice , Sandhya Pande
IPC分类号： C12N15/864 , C07K14/005
摘要： Described herein are polynucleotide constructs and stable cell lines for inducible production of rAAV virions within which are packaged a payload polynucleotide.
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公开(公告)号：US20240360473A1
公开(公告)日：2024-10-31
申请号：US18600530
申请日：2024-03-08
发明人： Kenneth Prentice , Sandhya Pande
IPC分类号： C12N15/86
CPC分类号： C12N15/86 , C12N2750/14143 , C12N2800/60
摘要： Described herein are compositions and methods of using stable cells lines in combination with transient transfection to produce recombinant AAV (rAAV).
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公开(公告)号：US12054738B2
公开(公告)日：2024-08-06
申请号：US17390777
申请日：2021-07-30
发明人： Kenneth Prentice , Sandhya Pande
IPC分类号： C07K14/005 , C12N15/864
CPC分类号： C12N15/8645 , C07K14/005 , C12N2750/14143 , C12N2750/14152
摘要： Described herein are polynucleotide constructs and stable cell lines for inducible production of rAAV virions within which are packaged a payload polynucleotide.
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公开(公告)号：US20240124850A1
公开(公告)日：2024-04-18
申请号：US18277033
申请日：2022-03-03
CPC分类号： C12N7/00 , C07K14/005 , C12N5/0018 , C12N5/0682 , C12N5/0686 , C12N9/0016 , C12N9/1007 , C12N9/93 , C12N15/52 , C12N2500/32 , C12N2501/999 , C12N2750/14122 , C12N2750/14151 , C12Y114/16001 , C12Y201/01045 , C12Y603/01002
摘要： Disclosed herein are cells and cell lines that are selected for retention of at least two exogenous nucleic acid constructs using a single selective pressure. Also disclosed herein are compositions and methods for generating recombinant cells and cell lines using a single selective pressure.
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