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    Method of separating alpha-L-aspartyl-L-phenylalanine methyl ester through crystallization
    1.
    发明授权
    Method of separating alpha-L-aspartyl-L-phenylalanine methyl ester through crystallization 失效
    通过结晶分离α-L-天冬氨酰-L-苯丙氨酸甲酯的方法

    公开(公告)号：US4994605A

    公开(公告)日：1991-02-19

    申请号：US342894

    申请日：1989-04-25

    申请人： Shinichi Kishimoto ,  Katsumi Sugiyama

    发明人： Shinichi Kishimoto ,  Katsumi Sugiyama

    IPC分类号： C07C231/00 ,  C07K1/14 ,  C07K5/072 ,  C07K5/075

    CPC分类号： C07K5/0613

    摘要： A method for crystallizing alpha-L-aspartyl-L-phenylalanine methyl ester (APM) is disclosed. The APM is crystallized from a C.sub.1 -C.sub.3 -alcohol/water solution (30-80:70-20 (v/v)). The ester crystallized by (i) concentrating the solution, (ii) cooling the solution, (iii) adjusting the water:alcohol ratio, or (iv) a combination thereof.

    摘要翻译： 公开了一种结晶α-L-天冬氨酰-L-苯丙氨酸甲酯（APM）的方法。 APM从C1-C3-醇/水溶液（30-80:70-20（v / v））中结晶。 所述酯通过（i）浓缩溶液，（ii）冷却溶液，（iii）调节水：醇比例，或（iv）其组合来结晶。

    MICRO RELAY
    3.
    发明申请
    MICRO RELAY 审中-公开
    微型继电器

    公开(公告)号：US20100182111A1

    公开(公告)日：2010-07-22

    申请号：US12664704

    申请日：2008-06-25

    申请人： Yosuke Hagihara ,  Takeshi Hashimoto ,  Riichi Uotome ,  Hideki Enomoto ,  Katsumi Kakimoto ,  Koji Yokoyama ,  Shinichi Kishimoto

    发明人： Yosuke Hagihara ,  Takeshi Hashimoto ,  Riichi Uotome ,  Hideki Enomoto ,  Katsumi Kakimoto ,  Koji Yokoyama ,  Shinichi Kishimoto

    IPC分类号： H01H45/00

    CPC分类号： H01H50/005 ,  H01H2001/0042 ,  H01H2050/007

    摘要： A micro relay includes a magnetic member and a permanent magnet in addition to a main substrate, a stationary contact, an armature and a coil. The magnetic member includes a core located in a first though hole of the main substrate. The permanent magnet is located at an end of the magnetic member or at a place within the magnetic member. The main substrate has a plurality of laminated layers. The coil is formed of a plurality of planer coils connected in series. The plurality of planer coils are formed on the plurality of laminated layers, respectively and are located around the core.

    摘要翻译： 除了主基板，固定触头，电枢和线圈之外，微型继电器还包括磁性构件和永磁体。 磁性构件包括位于主衬底的第一通孔中的芯。 永磁体位于磁性部件的端部或磁性部件内的位置。 主基板具有多个层叠层。 线圈由多个串联连接的平面线圈形成。 多个平面线圈分别形成在多个层叠层上，并且位于芯周围。

    Method and system for measuring blood coagulation time
    6.
    发明授权
    Method and system for measuring blood coagulation time 失效
    血液凝固时间测定方法及系统

    公开(公告)号：US4252536A

    公开(公告)日：1981-02-24

    申请号：US957927

    申请日：1978-11-06

    申请人： Shinichi Kishimoto ,  Masahiro Yoshioka

    发明人： Shinichi Kishimoto ,  Masahiro Yoshioka

    IPC分类号： G01N21/51 ,  C12Q1/56 ,  G01N11/00 ,  G01N21/27 ,  G01N21/47 ,  G01N33/49 ,  G01N33/86

    CPC分类号： G01N33/4905 ,  G01N21/272

    摘要： A blood coagulation time measuring method comprising irradiating a mixture of blood plasma and reagent with a beam of specified amount of light, detecting changes in the amount of light scattered by the mixture, converting the resulting scattered light output signals to digital form at specified time interval, feeding the digital data to a computer, computing the difference between each input value and the input value immediately adjacent thereto with respect to time and storing the results, and determining the time, prior to the time at which a maximum difference value is obtained, at which a computed difference value corresponding to 1/n of the maximum difference value is obtained. The time thus determined is the end point of the coagulation time. A system for practicing this method is also disclosed.

    摘要翻译： 一种凝血时间测定方法，其特征在于，使用规定量的光照射血浆和试剂的混合物，检测混合物散射的光的变化，将所得到的散射光输出信号以指定的时间间隔 将数字数据馈送到计算机，计算每个输入值和与其相邻的时间相对于其的输入值之间的差异并存储结果，并且确定在获得最大差值之前的时间， 其中获得对应于最大差值的1 / n的计算差值。 这样确定的时间是凝结时间的终点。 还公开了一种用于实施该方法的系统。

    Micro relay
    7.
    发明授权
    Micro relay 失效
    微型继电器

    公开(公告)号：US07482900B2

    公开(公告)日：2009-01-27

    申请号：US10556349

    申请日：2005-01-25

    申请人： Takeshi Hashimoto ,  Noriteru Furumoto ,  Naoki Okumura ,  Hideki Enomoto ,  Takeshi Sadamori ,  Shinichi Kishimoto ,  Tsutomu Shimomura ,  Kouji Sakai ,  Masami Hori

    发明人： Takeshi Hashimoto ,  Noriteru Furumoto ,  Naoki Okumura ,  Hideki Enomoto ,  Takeshi Sadamori ,  Shinichi Kishimoto ,  Tsutomu Shimomura ,  Kouji Sakai ,  Masami Hori

    IPC分类号： H01H67/02

    CPC分类号： H01H50/005 ,  H01H2050/007

    摘要： The micro relay of the present invention comprises a base substrate 3, an armature block 5, and a cover 7. The base substrate 3 has a storage recess 41 for accommodating an electromagnetic device 1. The storage recess is composed of a hole 41a penetrating the base substrate 3 and a thin storage recess lid fixed on the one surface of the base substrate to close the hole. The electromagnetic device 1 is isolated from a contact mechanism by the storage recess lid 41b to increase the reliability of the contacts. The electromagnetic device 1 includes a yoke 10, a coil 11 wound around the yoke to generate a flux in response to an exciting current, and a permanent magnet 12 secured to the yoke to generate a flux flowing through an armature 51 and the yoke 10. Because the permanent magnet 12 is secured to the yoke 10, this micro relay can reduce the thickness.

    摘要翻译： 本发明的微型继电器包括基底基板3，电枢块5和盖7.基底基板3具有用于容纳电磁装置1的储存凹部41.储存凹部由贯穿 基底基板3和固定在基底基板的一个表面上的薄的储存凹部盖以封闭孔。 电磁装置1通过存储凹部盖41b与接触机构隔离，以提高触点的可靠性。 电磁装置1包括磁轭10，卷绕在磁轭上以产生响应于励磁电流的磁通的线圈11和固定到磁轭的永磁体12，以产生流过电枢51和磁轭10的磁通。 因为永磁体12被固定到磁轭10上，所以这个微型继电器可以减小厚度。

    Micro relay
    8.
    发明申请
    Micro relay 失效
    微型继电器

    公开(公告)号：US20060250201A1

    公开(公告)日：2006-11-09

    申请号：US10556349

    申请日：2005-01-25

    申请人： Takeshi Hashimoto ,  Noriteru Furumoto ,  Naoki Okumura ,  Hideki Enomoto ,  Takeshi Sadamori ,  Shinichi Kishimoto ,  Tsutomu Shimomura ,  Kouji Sakai ,  Masami Hori

    发明人： Takeshi Hashimoto ,  Noriteru Furumoto ,  Naoki Okumura ,  Hideki Enomoto ,  Takeshi Sadamori ,  Shinichi Kishimoto ,  Tsutomu Shimomura ,  Kouji Sakai ,  Masami Hori

    IPC分类号： H01H51/22

    CPC分类号： H01H50/005 ,  H01H2050/007

    摘要： The micro relay of the present invention comprises a base substrate 3, an armature block 5, and a cover 7. The base substrate 3 has a storage recess 41 for accommodating an electromagnetic device 1. The storage recess is composed of a hole 41a penetrating the base substrate 3 and a thin storage recess lid fixed on the one surface of the base substrate to close the hole. The electromagnetic device 1 is isolated from a contact mechanism by the storage recess lid 41b to increase the reliability of the contacts. The electromagnetic device 1 includes a yoke 10, a coil 11 wound around the yoke to generate a flux in response to an exciting current, and a permanent magnet 12 secured to the yoke to generate a flux flowing through an armature 51 and the yoke 10. Because the permanent magnet 12 is secured to the yoke 10, this micro relay can reduce the thickness.

    摘要翻译： 本发明的微型继电器包括基底基板3，电枢块5和盖7.基底基底3具有用于容纳电磁装置1的储存凹部41.储存凹部由孔41穿透 基底基板3和固定在基底基板的一个表面上的薄的储存凹部盖以封闭孔。 电磁装置1通过存储凹部盖41b与接触机构隔离，以提高触点的可靠性。 电磁装置1包括磁轭10，卷绕在磁轭上以产生响应于励磁电流的磁通的线圈11和固定到磁轭的永磁体12，以产生流过电枢51和磁轭10的磁通。 因为永磁体12被固定到磁轭10上，所以这个微型继电器可以减小厚度。

    Method of measurement using scattered light
    10.
    发明授权
    Method of measurement using scattered light 失效
    使用散射光的测量方法

    公开(公告)号：US4697925A

    公开(公告)日：1987-10-06

    申请号：US665623

    申请日：1984-10-29

    申请人： Hiroshi Hyodo ,  Naoki Yamada ,  Kenichi Iwase ,  Shinichi Kishimoto

    发明人： Hiroshi Hyodo ,  Naoki Yamada ,  Kenichi Iwase ,  Shinichi Kishimoto

    IPC分类号： G01N21/17 ,  G01N21/49 ,  G01N21/51 ,  G01N21/59 ,  G01N21/75 ,  G01N21/82 ,  G01N33/86 ,  G01N21/00

    CPC分类号： G01N21/51 ,  G01N2021/5969 ,  G01N2201/08

    摘要： The test solution in the measuring cell is regarded to be divided into a plurality of sections, and the quantity of scattered light from each section is continuously measured to give a plurality of independent series of signal. This measurement is carried out by scanning the measuring cell with a minute light flux periodically to obtain a plurality of measurements in a period. Out of the series of signals obtained, those containing abnormal scattered light signal are eliminated to determine accurate concentration and reaction process.

    摘要翻译： 认为测量单元中的测试溶液被分成多个部分，并且连续地测量来自每个部分的散射光的量，以产生多个独立的信号序列。 该测量是通过周期性地以微小的光通量扫描测量单元以在一段时间内获得多个测量来进行的。 在获得的一系列信号中，消除了包含异常散射光信号的信号，以确定准确的浓度和反应过程。