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1.发明授权
公开(公告)号：US5785969A
公开(公告)日：1998-07-28
申请号：US600988
申请日：1996-07-22
IPC分类号： A61K47/48 , A61K49/00 , G01N33/543 , G01N33/569 , G01N33/94 , A61K39/395 , A61K47/44
CPC分类号： A61K49/0052 , A61K47/48038 , A61K47/48507 , A61K47/488 , A61K49/0043 , G01N33/5432 , G01N33/56966 , G01N33/94 , Y10S514/943 , Y10S977/808 , Y10S977/906 , Y10S977/918 , Y10S977/927
摘要： The new pharmaceutical and diagnostic compositions comprise antibody-aggregates and hydrophobic drug or marker molecules. The drug or marker molecules are solubilized inside micelle-like antibody-aggregates. In a process for preparing such types of compositions, hydrophobic residues are attached to the antibodies in the presence of a surface active agent. After removal of this agent the hydrophobic drug or marker molecules are solubilized inside the resulting antibody aggregates. A method for targeting molecules towards specific cells and sites within a living body is also disclosed.
摘要翻译： PCT No.PCT / EP94 / 02827 Sec。 371日期：1996年7月22日 102（e）日期1996年7月22日PCT 1994年8月25日PCT公布。 公开号WO95 / 06483 日期1995年3月9日新的药物和诊断组合物包含抗体聚集体和疏水性药物或标记分子。 药物或标记分子溶解在胶束样抗体聚集体内。 在制备这种类型的组合物的方法中，疏水残基在表面活性剂存在下连接到抗体上。 除去该试剂后，疏水性药物或标记物分子溶解在所得抗体聚集体内。 还公开了将分子靶向生物体内的特定细胞和位点的方法。
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2.发明授权Composition exhibiting enhanced formulation stability and delivery of topical active ingredients 有权表现出增强的制剂稳定性和局部活性成分递送的组合物公开(公告)号：US08449918B2
公开(公告)日：2013-05-28
申请号：US13243189
申请日：2011-09-23
申请人： Noa Lapidot , Shlomo Magdassi , David Avnir , Claudi Rottman , Orit Gans , Alon Seri-Levy
发明人： Noa Lapidot , Shlomo Magdassi , David Avnir , Claudi Rottman , Orit Gans , Alon Seri-Levy
IPC分类号： A61K9/14 , A61K9/00 , A61K31/07 , A61K31/19 , A61K31/327
CPC分类号： A61K8/042 , A61K8/11 , A61K8/25 , A61K8/37 , A61K8/38 , A61K8/602 , A61K8/671 , A61K9/501 , A61K9/5031 , A61K9/5115 , A61K9/5138 , A61K2800/412 , A61K2800/75 , A61Q1/00 , A61Q5/02 , A61Q5/12 , A61Q11/00 , A61Q17/04 , A61Q19/00 , B82Y5/00 , Y10S514/844 , Y10S514/937 , Y10S514/944 , Y10S514/945
摘要： A therapeutic, cosmetic or cosmeceutic composition for topical application, capable of stabilizing an active ingredient and delivering the active ingredient, comprising a plurality of microcapsules having a core-shell structure. The microcapsules have a diameter of approximately 0.1 to 100 micron. The core of each microcapsule includes at least one active ingredient, and is encapsulated within a microcapsular shell. The shell is comprised of at least one inorganic polymer obtained by a sol-gel process, and the shell protects the active ingredient before topical application and is designed to release the active ingredient from the microcapsules following application. The composition is useful in encapsulating active ingredients, such as benzoyl peroxide, that are unstable in other formulation, or are irritating to the skin.
摘要翻译： 一种用于局部施用的治疗性，化妆品或药妆组合物，其能够稳定活性成分并递送活性成分，其包含多个具有核 - 壳结构的微胶囊。 微胶囊的直径约为0.1至100微米。 每个微胶囊的核心包含至少一种活性成分，并被包封在微胶囊壳内。 该壳由至少一种通过溶胶 - 凝胶法获得的无机聚合物组成，并且外壳在局部施用之前保护活性成分，并且被设计成在施用后从微胶囊中释放活性成分。 该组合物可用于包封在其它制剂中不稳定或对皮肤有刺激性的活性成分，例如过氧化苯甲酰。
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公开(公告)号：US20090214840A1
公开(公告)日：2009-08-27
申请号：US11992536
申请日：2006-09-28
申请人： Gera Eron , Avi Feinschmidt , Shlomo Magdassi , Yelena Vinetsky , Eliane Liraz
发明人： Gera Eron , Avi Feinschmidt , Shlomo Magdassi , Yelena Vinetsky , Eliane Liraz
CPC分类号： C09D11/02 , B41J3/407 , B41J11/002 , B41M5/0023 , B41M5/007 , B41M7/0081 , C03C8/02 , C03C8/12 , C09D11/322 , Y10T428/24926
摘要： The invention relates to an ink-jet ink composition for printing on a ceramic substrate comprising: (a) a liquid vehicle; (b) sub-micron particles of binding composition having a melting point below 6000 C; and (c) sub-micron particles causing an etch-like effect, said sub-micron particles are selected from metal oxide particles, high melting point frit particles, and a combination thereof, said sub-micron particles causing an etch-like effect have a melting point of at least 500 C above the melting point of said sub-micron particles of binding composition. The invention further relates to a printing process using such ink and to a ceramic substrate printed with a pattern or image having an etch-like effect, by means of the printing process.
摘要翻译： 本发明涉及一种用于在陶瓷基片上印刷的喷墨油墨组合物，包括：（a）液体载体; （b）熔点低于6000℃的亚微米结合组合物颗粒; 所述亚微米颗粒选自金属氧化物颗粒，高熔点玻璃料颗粒及其组合，所述亚微米颗粒引起蚀刻效应具有 比所述亚微米结合组合物颗粒的熔点高至少500℃的熔点。 本发明还涉及使用这种油墨和通过印刷方法印刷有具有蚀刻效果的图案或图像的陶瓷基板的印刷方法。
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公开(公告)号：US20060051389A1
公开(公告)日：2006-03-09
申请号：US11250027
申请日：2005-10-13
申请人： Arnon Shani , Shlomo Magdassi , Ido Yosha
发明人： Arnon Shani , Shlomo Magdassi , Ido Yosha
CPC分类号： A01N25/18
摘要： The invention provides a sustained release, polymer-based, water insoluble bead, comprising a polymeric matrix containing a plurality of emulsion droplets, said droplets being formed from at least one surface active molecule, at lease one volatile hydrophobic component and water, wherein said volatile component is released from said water insoluble bead in atmospheric air.
摘要翻译： 本发明提供了一种持续释放的基于聚合物的水不溶性珠，其包含含有多个乳液液滴的聚合物基质，所述液滴由至少一种表面活性分子，至少一种挥发性疏水组分和水形成，其中所述挥发性 组分在大气中从所述水不溶性珠粒释放出来。
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5.发明授权Method of making positively charged microcapsules of emulsions of oils and its uses 失效制备带正电荷的乳状液微胶囊及其用途的方法
公开(公告)号：US5753264A
公开(公告)日：1998-05-19
申请号：US578855
申请日：1995-12-26
申请人： Shlomo Magdassi , Kosta Mumcuoglu , Uri Bach , Yulia Rosen
发明人： Shlomo Magdassi , Kosta Mumcuoglu , Uri Bach , Yulia Rosen
IPC分类号： A01N25/04 , A01N25/28 , A61K9/50 , A61K9/52 , A61K36/61 , A61K47/36 , B01J13/02 , A61K7/42 , A61K35/78
CPC分类号： B01J13/02 , A01N25/04 , A01N25/28 , A01N49/00 , A01N65/00 , A01N65/22 , A01N65/28 , A01N65/44 , A61K47/36 , A61K9/5036 , Y10S424/10 , Y10S514/88 , Y10S514/881 , Y10S514/919 , Y10S514/937 , Y10S514/938 , Y10S514/963 , Y10S514/975
摘要： The invention relates to a process for preparing a chitosan-containing microcapsules and emulsions of an oil including the steps of (a) forming an oil-in-water emulsion by homogenizing said oil into an aqueous solution containing an anionic emulsifier; and (b) adding to the emulsion obtained in (a) an aqueous chitosan solution while continuously homogenizing the mixture to give a stable emulsion, which is converted into microcapsules by using the proper electrolyte and pH changes. Also encompassed are preparations including as active ingredient a lice repelling agent, vitamin E or a UV radiation photoprotectant. The preparations may be sustained-release or long acting preparations.
摘要翻译： 本发明涉及一种制备含壳聚糖的微胶囊和油的乳液的方法，包括以下步骤：（a）通过将所述油均质化成含有阴离子乳化剂的水溶液形成水包油乳液; 和（b）将混合物中的（a）壳聚糖水溶液中得到的乳液加入，同时连续均化混合物，得到稳定的乳液，通过使用适当的电解质和pH变化将其转化成微胶囊。 还包括作为活性成分的虱子排斥剂，维生素E或UV辐射光保护剂的制剂。 制剂可以是持续释放或长效制剂。
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6.发明授权公开(公告)号：US09095133B2
公开(公告)日：2015-08-04
申请号：US12441321
申请日：2007-09-16
申请人： Shlomo Magdassi , Benny Dayan , Ganit Levi-Ruso
发明人： Shlomo Magdassi , Benny Dayan , Ganit Levi-Ruso
摘要： The present invention provides a redispersible powder and aqueous dispersions of nanoparticles of water insoluble organic pesticides. The invention further provides methods for preparing the redispersible powder and the aqueous dispersion, wherein the methods include preparation of an oil-in-water nanoemulsion or microemulsion and solvent removal. The present invention also provides pesticidal compositions of the redispersible powder or aqueous dispersions, and their agricultural use in combating pests.
摘要翻译： 本发明提供了可再分散粉末和水不溶性有机农药纳米颗粒的水分散体。 本发明还提供了制备可再分散粉末和水分散体的方法，其中所述方法包括制备水包油纳米乳液或微乳液和溶剂去除。 本发明还提供可再分散粉末或水性分散体的农药组合物及其在防治害虫中的农业用途。
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公开(公告)号：US20130287708A1
公开(公告)日：2013-10-31
申请号：US13992309
申请日：2011-12-08
申请人： Tova Silberstein , Rachel Lutz , Shlomo Magdassi , Barak Tzadok
发明人： Tova Silberstein , Rachel Lutz , Shlomo Magdassi , Barak Tzadok
CPC分类号： A61K31/70 , A61K8/345 , A61K8/44 , A61K8/553 , A61K8/63 , A61K8/64 , A61K8/73 , A61K8/737 , A61K8/922 , A61K8/97 , A61K8/988 , A61K36/00 , A61K45/06 , A61K2236/30 , A61Q5/02 , A61Q11/00 , A61Q19/00
摘要： Provided is an all natural composition including naturally-obtained plant extracts.
摘要翻译： 提供包括天然获得的植物提取物的全天然组合物。
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8.发明申请COMPOSITION EXHIBITING ENHANCED FORMULATION STABILITY AND DELIVERY OF TOPICAL ACTIVE INGREDIENTS 有权组合物展示增强配方稳定性和局部活性成分的输送公开(公告)号：US20120015014A1
公开(公告)日：2012-01-19
申请号：US13243189
申请日：2011-09-23
申请人： Noa LAPIDOT , Shlomo Magdassi , David Avnir , Claudi Rottman , Orit Gans , Alon Seri-Levy
发明人： Noa LAPIDOT , Shlomo Magdassi , David Avnir , Claudi Rottman , Orit Gans , Alon Seri-Levy
IPC分类号： A61K9/50 , A61K31/327 , A61P3/02 , A61Q19/00 , A61K31/07 , A61K8/67 , A61K8/38 , A61K8/11 , A61P17/10
CPC分类号： A61K8/042 , A61K8/11 , A61K8/25 , A61K8/37 , A61K8/38 , A61K8/602 , A61K8/671 , A61K9/501 , A61K9/5031 , A61K9/5115 , A61K9/5138 , A61K2800/412 , A61K2800/75 , A61Q1/00 , A61Q5/02 , A61Q5/12 , A61Q11/00 , A61Q17/04 , A61Q19/00 , B82Y5/00 , Y10S514/844 , Y10S514/937 , Y10S514/944 , Y10S514/945
摘要： A therapeutic, cosmetic or cosmeceutic composition for topical application, capable of stabilizing an active ingredient and delivering the active ingredient, comprising a plurality of microcapsules having a core-shell structure. The microcapsules have a diameter of approximately 0.1 to 100 micron. The core of each microcapsule includes at least one active ingredient, and is encapsulated within a microcapsular shell. The shell is comprised of at least one inorganic polymer obtained by a sol-gel process, and the shell protects the active ingredient before topical application and is designed to release the active ingredient from the microcapsules following application. The composition is useful in encapsulating active ingredients, such as benzoyl peroxide, that are unstable in other formulation, or are irritating to the skin.
摘要翻译： 一种用于局部施用的治疗性，化妆品或药妆组合物，其能够稳定活性成分并递送活性成分，其包含多个具有核 - 壳结构的微胶囊。 微胶囊的直径约为0.1至100微米。 每个微胶囊的核心包含至少一种活性成分，并被包封在微胶囊壳内。 壳由至少一种通过溶胶 - 凝胶法获得的无机聚合物组成，并且外壳在局部施用之前保护活性成分，并被设计成在施用后从微胶囊中释放活性成分。 该组合物可用于包封在其它制剂中不稳定或对皮肤有刺激性的活性成分，例如过氧化苯甲酰。
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公开(公告)号：US20100068409A1
公开(公告)日：2010-03-18
申请号：US12418016
申请日：2009-04-03
申请人： Arkady Garbar , Dmitry Lekhtman , Fernando De La Vega , Shlomo Magdassi , Alexander Kamyshny , Frigita Kahana
发明人： Arkady Garbar , Dmitry Lekhtman , Fernando De La Vega , Shlomo Magdassi , Alexander Kamyshny , Frigita Kahana
CPC分类号： C09D11/36 , C09D11/322 , H01B1/22 , H05K1/097 , H05K3/125 , H05K2203/013
摘要： In jet printable compositions that include nano metal powders in a liquid carrier.
摘要翻译： 在包括液体载体中的纳米金属粉末的喷墨印刷组合物中。
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公开(公告)号：US20090074910A1
公开(公告)日：2009-03-19
申请号：US11884791
申请日：2006-02-22
IPC分类号： A23G4/06
CPC分类号： A23G4/06
摘要： Disclosed are chewing gums that are organoleptically acceptable, and have high adherence to plaque bacteria. A chewing gum according to an exemplary embodiment contains a gum base, at least one edible acid, and optionally other ingredients. The invention also provides a method for preparing a chewing gum composition, which includes triturating of coloring agent, and a method for commercially producing and marketing chewing gums, which includes testing the chewing gums for adhesion to bacteria, such as plaque bacteria.
摘要翻译： 公开了具有感觉上可接受的口香糖，并且对斑块细菌具有高粘附性。 根据示例性实施方案的口香糖包含胶基，至少一种食用酸和任选的其它成分。 本发明还提供了一种制备口香糖组合物的方法，其包括着色剂的研磨，以及用于商业生产和销售口香糖的方法，其包括测试口香糖以粘附细菌如斑块细菌。
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