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公开(公告)号：US09604978B2
公开(公告)日：2017-03-28
申请号：US14115506
申请日：2012-05-03
申请人： Shoujun Chen , Gary Bohnert , Jun Jiang , Zhiqiang Xia
发明人： Shoujun Chen , Gary Bohnert , Jun Jiang , Zhiqiang Xia
IPC分类号： A61K31/4965 , C07D401/12 , C07D417/14 , A61K31/165 , A61K31/44 , A61K31/497 , C07D401/14 , C07D405/14 , C07D413/14 , C07D213/82
CPC分类号： C07D417/14 , A61K31/165 , A61K31/44 , A61K31/497 , C07D213/82 , C07D401/12 , C07D401/14 , C07D405/14 , C07D413/14
摘要： The invention relates to certain compounds or pharmaceutically acceptable salts, solvates, clathrates, or prodrugs thereof, that are useful as immunosuppressive agents and for treating and preventing inflammatory conditions, allergic disorders, and immune disorders.
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公开(公告)号：US20120283272A1
公开(公告)日：2012-11-08
申请号：US13552755
申请日：2012-07-19
申请人： Shoujun Chen , Junyi Zhang , Jun Jiang , Gary Bohnert , Nha Vo , Qinglin Che , Zhiqiang Xia , Lijun Sun
发明人： Shoujun Chen , Junyi Zhang , Jun Jiang , Gary Bohnert , Nha Vo , Qinglin Che , Zhiqiang Xia , Lijun Sun
IPC分类号： A61K31/444 , C07D417/04 , A61K31/497 , A61K31/4436 , C07D409/06 , C07D409/14 , C07D417/14 , A61K31/4439
CPC分类号： C07D417/14 , C07D409/04 , C07D409/06 , C07D409/14 , C07D413/04 , C07D413/14 , C07D417/04
摘要： The invention relates to certain compounds, or pharmaceutically acceptable salts, solvates, clathrates, or prodrugs thereof, that are useful as immunosuppressive agents and for treating and preventing inflammatory conditions, allergic disorders, and immune disorders.
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公开(公告)号：US20140171446A1
公开(公告)日：2014-06-19
申请号：US14115506
申请日：2012-05-03
申请人： Shoujun Chen , Gary Bohnert , Jun Jiang , Zhiqiang Xia
发明人： Shoujun Chen , Gary Bohnert , Jun Jiang , Zhiqiang Xia
IPC分类号： C07D417/14 , C07D405/14 , C07D401/12 , C07D401/14 , C07D213/82
CPC分类号： C07D417/14 , A61K31/165 , A61K31/44 , A61K31/497 , C07D213/82 , C07D401/12 , C07D401/14 , C07D405/14 , C07D413/14
摘要： The invention relates to certain compounds or pharmaceutically acceptable salts, solvates, clathrates, or prodrugs thereof, that are useful as immunosuppressive agents and for treating and preventing inflammatory conditions, allergic disorders, and immune disorders.
摘要翻译： 本发明涉及可用作免疫抑制剂并用于治疗和预防炎性病症，过敏性疾病和免疫疾病的某些化合物或其药学上可接受的盐，溶剂合物，包合物或前药。
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公开(公告)号：US20130165451A9
公开(公告)日：2013-06-27
申请号：US13552755
申请日：2012-07-19
申请人： Shoujun Chen , Junyi Zhang , Jun Jiang , Gary Bohnert , Nha Vo , Qinglin Che , Zhiqiang Xia , Lijun Sun
发明人： Shoujun Chen , Junyi Zhang , Jun Jiang , Gary Bohnert , Nha Vo , Qinglin Che , Zhiqiang Xia , Lijun Sun
IPC分类号： A61K31/444 , C07D417/04 , A61K31/497 , A61K31/4436 , C07D409/06 , C07D409/14 , C07D417/14 , A61K31/4439
CPC分类号： C07D417/14 , C07D409/04 , C07D409/06 , C07D409/14 , C07D413/04 , C07D413/14 , C07D417/04
摘要： The invention relates to certain compounds, or pharmaceutically acceptable salts, solvates, clathrates, or prodrugs thereof, that are useful as immunosuppressive agents and for treating and preventing inflammatory conditions, allergic disorders, and immune disorders.
摘要翻译： 本发明涉及可用作免疫抑制剂并用于治疗和预防炎性病症，过敏性疾病和免疫疾病的某些化合物或其药学上可接受的盐，溶剂化物，包合物或前药。
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5.发明授权Compounds inclunding substituted pyridines for inflammation and immune-related uses 失效包含取代吡啶类化合物用于炎症和免疫相关用途的化合物公开(公告)号：US08314130B2
公开(公告)日：2012-11-20
申请号：US12572103
申请日：2009-10-01
申请人： Shoujun Chen , Junyi Zhang , Jun Jiang , Gary Bohnert , Nha Vo , Qinglin Che , Zhiqiang Xia , Lijun Sun
发明人： Shoujun Chen , Junyi Zhang , Jun Jiang , Gary Bohnert , Nha Vo , Qinglin Che , Zhiqiang Xia , Lijun Sun
IPC分类号： A61K31/44
CPC分类号： C07D417/14 , C07D409/04 , C07D409/06 , C07D409/14 , C07D413/04 , C07D413/14 , C07D417/04
摘要： The invention relates to certain compounds including substituted pyridines, or pharmaceutically acceptable salts, solvates, clathrates, or prodrugs thereof, that are useful as immunosuppressive agents and for treating and preventing inflammatory conditions, allergic disorders, and immune disorders.
摘要翻译： 本发明涉及可用作免疫抑制剂并用于治疗和预防炎性病症，过敏性疾病和免疫疾病的某些化合物，包括取代的吡啶或其药学上可接受的盐，溶剂合物，包合物或前药。
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公开(公告)号：US20100130510A1
公开(公告)日：2010-05-27
申请号：US12572103
申请日：2009-10-01
申请人： SHOUJUN CHEN , Junyi Zhang , Jun Jiang , Gary Bohnert , Nha Vo , Qinglin Che , Zhiqiang Xia , Lijun Sun
发明人： SHOUJUN CHEN , Junyi Zhang , Jun Jiang , Gary Bohnert , Nha Vo , Qinglin Che , Zhiqiang Xia , Lijun Sun
IPC分类号： A61K31/497 , A61K31/444 , A61K31/4439 , C07D409/14 , C07D401/14 , C07D417/04 , A61P25/28 , A61P19/02 , A61P3/10 , A61P17/00 , A61P37/00 , A61P11/06 , A61P19/08 , A61P25/16
CPC分类号： C07D417/14 , C07D409/04 , C07D409/06 , C07D409/14 , C07D413/04 , C07D413/14 , C07D417/04
摘要： The invention relates to certain compounds, or pharmaceutically acceptable salts, solvates, clathrates, or prodrugs thereof, that are useful as immunosuppressive agents and for treating and preventing inflammatory conditions, allergic disorders, and immune disorders.
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公开(公告)号：US20110118281A9
公开(公告)日：2011-05-19
申请号：US12572079
申请日：2009-10-01
申请人： Gary Bohnert , Zhiqiang Xia , Shoujun Chen , Lijun Sun
发明人： Gary Bohnert , Zhiqiang Xia , Shoujun Chen , Lijun Sun
IPC分类号： C07D401/04 , A61K31/497 , A61K31/4436 , C07D417/04 , C12N5/00 , A61P29/00 , A61P37/00 , A61P19/02 , A61P17/00 , A61P37/08
CPC分类号： C07D401/04 , A61K31/497 , A61K45/06 , C07D211/96 , C07D401/14 , C07D417/04 , C07D417/14
摘要： The invention relates to certain compounds, or pharmaceutically acceptable salts, solvates, clathrates, or prodrugs thereof, that are useful as immunosuppressive agents and for treating and preventing inflammatory conditions, allergic disorders, and immune disorders.
摘要翻译： 本发明涉及可用作免疫抑制剂并用于治疗和预防炎性病症，过敏性疾病和免疫疾病的某些化合物或其药学上可接受的盐，溶剂化物，包合物或前药。
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公开(公告)号：US20120183579A1
公开(公告)日：2012-07-19
申请号：US13351351
申请日：2012-01-17
申请人： Gary Bohnert , Zhiqiang Xia , Shoujun Chen , Lijun Sun
发明人： Gary Bohnert , Zhiqiang Xia , Shoujun Chen , Lijun Sun
IPC分类号： A61K45/00 , A61K31/56 , A61K31/497 , A61K31/444 , A61K31/4439 , A61K31/4418 , A61K31/44 , C07D417/14 , C07D401/14 , C07D401/04 , C07D417/04 , C07D211/98 , C07D211/96 , A61P37/06 , A61P29/00 , A61P37/08 , A61P25/00 , A61P7/06 , A61P19/02 , A61P17/06 , A61P1/00 , A61P3/10 , A61P19/08 , A61P11/00 , A61P11/06 , A61P31/14 , A61P25/28 , A61P9/10 , A61P15/00 , A61P1/16 , A61P35/00 , A61P25/16 , C12N5/02
CPC分类号： C07D401/04 , A61K31/497 , A61K45/06 , C07D211/96 , C07D401/14 , C07D417/04 , C07D417/14
摘要： The invention relates to certain compounds, or pharmaceutically acceptable salts, solvates, clathrates, or prodrugs thereof, that are useful as immunosuppressive agents and for treating and preventing inflammatory conditions, allergic disorders, and immune disorders.
摘要翻译： 本发明涉及可用作免疫抑制剂并用于治疗和预防炎性病症，过敏性疾病和免疫疾病的某些化合物或其药学上可接受的盐，溶剂化物，包合物或前药。
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公开(公告)号：US20100125080A1
公开(公告)日：2010-05-20
申请号：US12572079
申请日：2009-10-01
申请人： Gary Bohnert , Zhiqiang Xia , Shoujun Chen , Lijun Sun
发明人： Gary Bohnert , Zhiqiang Xia , Shoujun Chen , Lijun Sun
IPC分类号： C07D401/04 , A61K31/497 , A61K31/4436 , C07D417/04 , C12N5/00 , A61P29/00 , A61P37/00 , A61P19/02 , A61P17/00 , A61P37/08
CPC分类号： C07D401/04 , A61K31/497 , A61K45/06 , C07D211/96 , C07D401/14 , C07D417/04 , C07D417/14
摘要： The invention relates to certain compounds, or pharmaceutically acceptable salts, solvates, clathrates, or prodrugs thereof, that are useful as immunosuppressive agents and for treating and preventing inflammatory conditions, allergic disorders, and immune disorders.
摘要翻译： 本发明涉及可用作免疫抑制剂并用于治疗和预防炎性病症，过敏性疾病和免疫疾病的某些化合物或其药学上可接受的盐，溶剂化物，包合物或前药。
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公开(公告)号：US20130142831A1
公开(公告)日：2013-06-06
申请号：US13652878
申请日：2012-10-16
申请人： Shoujun Chen , Jun Jiang , Hao Li , David James , Dinesh Chimmanamada , Christopher Borella , Lijun Sun , Yu Xie , Mats Holmqvist , Jerome Mahiou , Zhiqiang Xia
发明人： Shoujun Chen , Jun Jiang , Hao Li , David James , Dinesh Chimmanamada , Christopher Borella , Lijun Sun , Yu Xie , Mats Holmqvist , Jerome Mahiou , Zhiqiang Xia
IPC分类号： A61K31/437
CPC分类号： A61K31/437 , A61K31/403 , A61K31/4184 , A61K31/4439 , A61K31/444 , A61K31/537 , C07D235/06 , C07D235/08 , C07D235/10 , C07D235/24 , C07D235/28 , C07D401/12 , C07D403/04 , C07D403/12 , C07D405/12 , C07D409/12 , C07D413/04 , C07D413/14 , C07D417/12 , C07D471/04 , Y02A50/422
摘要： The invention relates to compounds of formula (I): or a pharmaceutically acceptable salt, solvate, clathrate, or prodrug thereof wherein X, Y, A, Z, L and n are defined herein. These compounds are useful as immunosuppressive agents and for treating and preventing inflammatory conditions and immune disorders.
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