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公开(公告)号:US06589937B1
公开(公告)日:2003-07-08
申请号:US09171245
申请日:1998-10-14
申请人: Shuichi Tanabe , Yoshiyuki Shishido , Masayoshi Furushiro , Kunio Kado , Shusuke Hashimoto , Teruo Yokokura , Tetsuya Terasaki
发明人: Shuichi Tanabe , Yoshiyuki Shishido , Masayoshi Furushiro , Kunio Kado , Shusuke Hashimoto , Teruo Yokokura , Tetsuya Terasaki
IPC分类号: A61K3803
CPC分类号: C07K7/16 , A61K38/00 , C07K5/1019
摘要: New peptides represented by the following general formula (wherein X is OH or NH2, R is an amino acid residue selected from Arg, His, Lys, Methyl-Arg or Methyl-Tyr, n is an integer of 1-4, and in the case that n is 2-4, R may be identical with or different from each other) and an anti-dementia drug which contains one or more of these new peptides and has a high blood brain barrier (BBB) permeability and furthermore is low in a side effect.
摘要翻译: 由以下通式表示的新肽(其中X为OH或NH 2,R为选自Arg,His,Lys,Methyl-Arg或Methyl-Tyr的氨基酸残基,n为1-4的整数, n为2-4的情况,R可以相同或不同)和含有这些新肽中的一种或多种且具有高血脑屏障(BBB)渗透性的抗痴呆药物,此外,低 副作用。
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公开(公告)号:US5475089A
公开(公告)日:1995-12-12
申请号:US75545
申请日:1993-06-14
申请人: Osamu Matsuo , Masashi Sakai , Kisaku Shimura , Hiroshi Sansawa , Tsunekazu Watanabe , Tsuneo Matsumoto , Yoshiyuki Shishido , Shusuke Hashimoto , Teruo Yokokura , Masaharu Onoue , Tomoyuki Sako
发明人: Osamu Matsuo , Masashi Sakai , Kisaku Shimura , Hiroshi Sansawa , Tsunekazu Watanabe , Tsuneo Matsumoto , Yoshiyuki Shishido , Shusuke Hashimoto , Teruo Yokokura , Masaharu Onoue , Tomoyuki Sako
CPC分类号: C07K14/31
摘要: A thrombolytic peptide composed of 136 amino acids residues, which has little problems of antigenicity and is efficacious in only small doses as compared with staphylokinase (SAK). This peptide is obtained by cleaving amino acids or peptides which do not affect the activity of SAK by using a trypsin protease. In particular, SAK-11, which is obtained by cleaving a peptide composed of ten amino acid residues at the N-terminal of SAK, is superior to SAK in the fibrinolysis, plasminogen activation, and fibrin specificity.
摘要翻译: PCT No.PCT / JP91 / 01722 Sec。 371日期:1993年6月14日 102(e)日期1993年6月14日PCT 1991年12月17日PCT公布。 出版物WO92 / 11356 日期:1992年7月9日。一种由136个氨基酸残基组成的血栓溶解肽,与葡萄球菌激酶(SAK)相比,其抗原性问题很小,仅有小剂量有效。 通过使用胰蛋白酶蛋白酶切割不影响SAK活性的氨基酸或肽来获得该肽。 特别地,通过在SAK的N末端切割由10个氨基酸残基构成的肽获得的SAK-11在纤维蛋白溶解,纤溶酶原激活和纤维蛋白特异性方面优于SAK。
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公开(公告)号:US20050000375A1
公开(公告)日:2005-01-06
申请号:US10898331
申请日:2004-07-26
CPC分类号: B41L13/06
摘要: A stencil printer of the present invention perforates, or cuts, a thermosensitive stencil with a thermal head to thereby make a master. The stencil printer includes a stencil distinguishing device for automatically identifying the kind of the stencil or a master setting device for allowing the operator of the printer to set the kind of the stencil. An adjusting device selects, among master making conditions experimentally determined beforehand, a master making condition matching with information output from the stencil distinguishing device or the stencil setting device. The operator can easily change the master making condition in accordance with the kind of a stencil to use.
摘要翻译: 本发明的模版印刷机用热敏头打孔或切割热敏蜡纸,从而制成主机。 模板印刷机包括用于自动识别模板的种类的模板识别装置或用于允许打印机的操作者设置模板的种类的主设置装置。 调整装置在预先通过实验确定的主制作条件中选择与从模板识别装置或模板设定装置输出的信息相匹配的主制作条件。 操作员可以根据使用的模板的种类轻松地改变主制作条件。
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4.
公开(公告)号:US06836276B2
公开(公告)日:2004-12-28
申请号:US10650766
申请日:2003-08-29
IPC分类号: B41J236
摘要: A thermal master making device and a thermal printer including the same are disclosed. A thermistor senses ambient temperature around a thermal head. A correcting device corrects the amount of heat to be generated by the thermal head, i.e., the duration of energization at least two times during a single master making operation. This configuration reduces a change in the perforation conditions of a thermosensitive medium ascribable to the heat accumulation characteristic of the head. The printer achieves high resolution, high-speed master making and space saving.
摘要翻译: 公开了一种热敏主制造装置和包括其的热敏打印机。 热敏电阻感测热头周围的环境温度。 校正装置在单个主制造操作期间校正由热头产生的热量,即通电持续时间至少两次。 该构造减少了由于头部的热积聚特性引起的热敏介质的穿孔条件的变化。 打印机实现了高分辨率,高速的制作和节省空间。
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公开(公告)号:US20160248336A1
公开(公告)日:2016-08-25
申请号:US15044066
申请日:2016-02-15
IPC分类号: H02M5/458
CPC分类号: H02M5/458 , H02M7/537 , H02M2001/0009
摘要: An inverter device applies an excitation current to an excitation winding of a step-up transformer through a switching element, and outputs an output voltage with an alternating-current half-wave waveform from an output winding of the step-up transformer. The inverter device includes: an input-voltage detecting unit that detects a state of the input voltage, as a voltage; a current detecting unit that converts a current flowing through the switching element into a voltage to detects the current; and a comparing unit that compares a detected current value detected by the current detecting unit with a detected input voltage value detected by the input-voltage detecting unit, and detects a high-current period in which the detected current value exceeds the detected input voltage value. Based on information indicating the high-current period detected by the comparing unit, the control circuit adjusts a period in which the switching element is turned on.
摘要翻译: 逆变器装置通过开关元件向升压变压器的励磁绕组施加励磁电流,并且从升压变压器的输出绕组输出具有交流半波形的输出电压。 逆变器装置包括:输入电压检测单元,其将输入电压的状态检测为电压; 电流检测单元,其将流过开关元件的电流转换成电压以检测电流; 以及比较单元,其将由所述电流检测单元检测到的检测电流值与由所述输入电压检测单元检测出的检测输入电压值进行比较,并且检测检测到的电流值超过所检测的输入电压值的高电流周期 。 基于表示由比较部检测出的高电流期间的信息,控制电路调整开关元件导通的期间。
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公开(公告)号:US20090179928A1
公开(公告)日:2009-07-16
申请号:US12354267
申请日:2009-01-15
申请人: Yusuke NEMOTO , Yoshihiko Kudoh , Akira Saito , Yoshiyuki Shishido , Yukitaka Watarai , Hiroyuki Hiratsuka , Susumu Shirauchi , Shin-ichi Shoji
发明人: Yusuke NEMOTO , Yoshihiko Kudoh , Akira Saito , Yoshiyuki Shishido , Yukitaka Watarai , Hiroyuki Hiratsuka , Susumu Shirauchi , Shin-ichi Shoji
IPC分类号: B41J25/308
CPC分类号: B41J2/16585
摘要: An image-forming apparatus includes a head unit configured to include line-type recording heads for ejecting ink droplets, a transport mechanism disposed facing the recording head and configured to transport a sheet, a maintain-recovery mechanism disposed downstream from the transport mechanism in a direction in which the sheet is transported and configured to maintain and recover the line type recording heads, and a head drive mechanism configured to move the head unit between a position facing the transport mechanism and a position facing the maintain-recovery mechanism in the direction in which the sheet is transported.
摘要翻译: 图像形成装置包括头单元,该头单元被配置为包括用于喷射墨滴的线型记录头,与该记录头相对设置并构造成输送片材的输送机构,在该输送机构的下游设置的维持恢复机构 方向,其中片材被输送和构造成维持和恢复线型记录头;以及头驱动机构,其构造成使头单元在面向输送机构的位置和面向维护恢复机构的位置之间沿着 该片材被运送。
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公开(公告)号:US06747682B2
公开(公告)日:2004-06-08
申请号:US09773915
申请日:2001-02-02
IPC分类号: B41J236
摘要: A thermal master making device and a thermal printer including the same are disclosed. A thermistor senses ambient temperature around a thermal head. A correcting device corrects the amount of heat to be generated by the thermal head, i.e., the duration of energization at least two times during a single master making operation. This configuration reduces a change in the perforation conditions of a thermosensitive medium ascribable to the heat accumulation characteristic of the head. The printer achieves high resolution, high-speed master making and space saving.
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公开(公告)号:US06664992B1
公开(公告)日:2003-12-16
申请号:US09528032
申请日:2000-03-17
IPC分类号: B41J2335
CPC分类号: B41C1/144 , B41J2/33545 , B41J2/3356 , B41J2/3357 , B41J2202/32
摘要: A master making device includes a thermal head with heat generating elements and a platen roller. While the head and platen roller convey a thermosensitive medium in a subscanning direction perpendicular to a main scanning direction, the heat generating elements selectively generate heat in order to perforate the medium in accordance with an image signal. The head includes a stepped portion formed at a medium outlet side in the subscanning direction. The edges of the heat generating elements adjoining the medium outside side are located at a distance of 0.018 mm to 0.5 mm from the end of the stepped portion adjoining the above edges. It is not necessary to position the head with respect to an effective nip between it and the platen roller by a troublesome procedure. Further, the distance over which the perforated medium is conveyed is reduced to obviate the reduction or contraction of an image ascribable to the sticking of the medium to the head.
摘要翻译: 主制造装置包括具有发热元件的热敏头和压纸辊。 当头部和压纸辊在垂直于主扫描方向的副扫描方向上传送热敏介质时,发热元件选择性地产生热量,以便根据图像信号对介质进行穿孔。 头包括形成在副扫描方向上的介质出口侧的台阶部分。 与介质外侧相邻的发热元件的边缘位于与上述边缘相邻的台阶部分的端部0.018mm至0.5mm的距离处。 通过麻烦的过程,不需要相对于其与压纸辊之间的有效压区来定位头部。 此外,减少了穿孔介质被输送的距离,以消除由于介质粘附到头部而引起的图像的减少或收缩。
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公开(公告)号:US5685222A
公开(公告)日:1997-11-11
申请号:US398943
申请日:1995-03-02
摘要: A control device for a thermosensitive stencil printer which is capable of perforating a stencil in an optimal configuration matching a desired resolution in the subscanning direction and thereby producing desirable images. The device allows perforations to be formed in a stencil in an adequate size in the subscanning direction. Heating portions included in a thermal head are each sized, in the subscanning direction, smaller than a feed pitch corresponding to the highest resolution available with a resolution setting device.
摘要翻译: 一种用于热敏模版印刷机的控制装置,其能够以与副扫描方向上的期望分辨率匹配的最佳配置穿孔模板,从而产生期望的图像。 该装置允许在副扫描方向上以足够的尺寸在模板中形成穿孔。 包括在热敏头中的加热部分在副扫描方向上的尺寸均大于对应于分辨率设置装置可用的最高分辨率的进给间距。
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公开(公告)号:US09819280B2
公开(公告)日:2017-11-14
申请号:US15044066
申请日:2016-02-15
CPC分类号: H02M5/458 , H02M7/537 , H02M2001/0009
摘要: An inverter device applies an excitation current to an excitation winding of a step-up transformer through a switching element, and outputs an output voltage with an alternating-current half-wave waveform from an output winding of the step-up transformer. The inverter device includes: an input-voltage detecting unit that detects a state of the input voltage, as a voltage; a current detecting unit that converts a current flowing through the switching element into a voltage to detects the current; and a comparing unit that compares a detected current value detected by the current detecting unit with a detected input voltage value detected by the input-voltage detecting unit, and detects a high-current period in which the detected current value exceeds the detected input voltage value. Based on information indicating the high-current period detected by the comparing unit, the control circuit adjusts a period in which the switching element is turned on.
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