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24 条记录 (耗时 0.033 秒)

    Antiulcer agent and process for preparing the same
    2.
    发明授权
    Antiulcer agent and process for preparing the same 失效
    抗溃疡剂及其制备方法

    公开(公告)号：US5698534A

    公开(公告)日：1997-12-16

    申请号：US202642

    申请日：1994-02-28

    申请人： Masato Nagaoka ,  Shusuke Hashimoto ,  Tsunekazu Watanabe ,  Teruo Yokokura

    发明人： Masato Nagaoka ,  Shusuke Hashimoto ,  Tsunekazu Watanabe ,  Teruo Yokokura

    IPC分类号： A61K31/70 ,  A61K31/715 ,  A61P1/04 ,  C07H3/08 ,  C08B37/00 ,  C12P19/06 ,  C12R1/01

    CPC分类号： A61K31/7004 ,  A61K31/715

    摘要： An antiulcer agent effective on prevention of ulceration and acceleration of healing of ulcers and processes for preparing the same are disclosed. The antiulcer agent comprises rhamnan (a homopolysaccharide), rhamnose or a rhamnose oligomer as an active ingredient. Rhamnan is prepared by separating rhamnan sulfate from rhamnan sulfate-containing algae and desulfurating the rhamnan sulfate. Rhamnan oligomers are prepared by hydrolyzing rhamnan obtained by desulfuration of rhamnan sulfate or by hydrolyzing microbial cells of a Bifidobacterium or polysaccharides separated therefrom.

    摘要翻译： 公开了一种有效预防溃疡溃疡和加速溃疡愈合的抗溃疡剂及其制备方法。 抗溃疡剂含有作为活性成分的鼠李糖（均聚多糖），鼠李糖或鼠李糖寡聚物。 鼠李糖通过从含有硫酸鼠李糖的藻类中分离出硫酸鼠李糖并且将硫酸鼠李糖硫酸盐脱硫来制备。 通过水解通过硫酸鼠李糖硫酸脱硫获得的鼠李糖或通过水解分离的双歧杆菌或多糖的微生物细胞来制备鼠李糖低聚物。

    Antibacterial agents and process for producing the same
    7.
    发明授权
    Antibacterial agents and process for producing the same 失效
    抗菌剂及其制造方法

    公开(公告)号：US07498317B2

    公开(公告)日：2009-03-03

    申请号：US11049423

    申请日：2005-02-02

    申请人： Masato Nagaoka ,  Hideyuki Shibata ,  Itsuko Takagi ,  Shusuke Hashimoto

    发明人： Masato Nagaoka ,  Hideyuki Shibata ,  Itsuko Takagi ,  Shusuke Hashimoto

    IPC分类号： A61K31/731 ,  A61K31/737

    CPC分类号： A61K31/702 ,  A61K31/731 ,  A61K31/737

    摘要： An antibacterial agent showing a high affinity for Helicobactor pyroli and having an antibacterial effect specific to H. Pyroli. The agent has a chemical structure wherein an antibacterial substance is bonded to a sulfated polysaccharide or an oligosaccharide prepared by partial decomposition of the sulfated polysaccharide. Preferable embodiments are those having the chemical structure represented by Y—OCH(AH2NHR)n or Y—BH2NHR, wherein Y represents a sulfated polysaccharide or an oligosaccharide prepared by partial decomposition of the sulfated polysaccharide; A a carbon derived from aldehyde group occurring through the reduction of the reduced end sugar of Y and subsequent oxidation of the resulting product with an oxidant; B a carbon derived from the aldehyde group at the reduced end sugar of Y; R an antibacterial substance with a primary amino group or with an amino group introduced therein or represents an antibacterial substance derivative prepared by bonding an antibacterial substance through a spacer to the carbon A or the carbon B; and n=1 or 2.

    摘要翻译： 对Helicobactor pyroli具有高亲和力并具有对H. Pyroli特异性的抗菌作用的抗菌剂。 该药剂具有抗菌物质与通过硫酸化多糖的部分分解制备的硫酸化多糖或寡糖结合的化学结构。 优选的实施方案是具有由Y-OCH（AH2NHR）n或Y-BH2NHR表示的化学结构的那些，其中Y表示硫酸化多糖或通过硫酸化多糖的部分分解制备的寡糖; 衍生自醛基的碳通过还原末端糖的Y而发生，随后用氧化剂氧化所得产物; B是衍生自Y的还原末端糖的醛基的碳; R是具有伯氨基或在其中引入氨基的抗菌物质，或代表通过间隔剂将抗菌物质与碳A或碳B结合而制备的抗菌物质衍生物; n = 1或2。

    Medical lighting apparatus and medical imaging apparatus
    8.
    发明申请
    Medical lighting apparatus and medical imaging apparatus 有权
    医疗照明器具及医疗成像仪器

    公开(公告)号：US20080239697A1

    公开(公告)日：2008-10-02

    申请号：US12075715

    申请日：2008-03-13

    申请人： Naoki Katsuda ,  Shusuke Hashimoto ,  Kazunari Matoba ,  Shinichi Okawa ,  Hiroaki Kusakabe ,  Yuzo Nakayama

    发明人： Naoki Katsuda ,  Shusuke Hashimoto ,  Kazunari Matoba ,  Shinichi Okawa ,  Hiroaki Kusakabe ,  Yuzo Nakayama

    IPC分类号： A61G13/00

    CPC分类号： A61B1/24 ,  A61B1/0607 ,  A61B1/0669 ,  A61B1/0684 ,  A61G13/10 ,  F21W2131/202 ,  F21Y2115/10

    摘要： An object of the preset invention is to provide a medical lighting apparatus capable of illuminating an affected part with proper illuminance while assuring a work space for an operator near the affected part. A medical lighting apparatus for irradiating an affected part with light includes: a light source (a light emitting element); a light condenser (a collimate lens and a condenser lens) for condensing light emitted from the light source; an image forming unit (an image lens) for forming an image on the affected part from the light condensed by the light condenser; and an aperture portion provided between the light condenser and the image forming unit and regulating passage of the light condensed by the light condenser.

    摘要翻译： 本发明的目的是提供一种能够以适当的照度照亮受影响部位的医疗照明装置，同时确保受影响部位附近的操作者的工作空间。 用于照射受影响部位的光的医疗照明装置包括：光源（发光元件）; 用于聚集从光源发出的光的光聚光器（准直透镜和聚光透镜）; 用于从由所述光聚光器会聚的光形成所述患部的图像的图像形成单元（图像透镜）; 以及设置在光聚光器和图像形成单元之间的开口部分，并且调节由光聚光器会聚的光的通过。

    Phenanthroindolizidine compound and NFκB inhibitor containing same as active ingredient
    9.
    发明授权
    Phenanthroindolizidine compound and NFκB inhibitor containing same as active ingredient 有权
    菲并吲哚哩啶化合物和含有与活性成分相同的NF＆kgr B抑制剂

    公开(公告)号：US09174979B2

    公开(公告)日：2015-11-03

    申请号：US13125698

    申请日：2009-10-23

    申请人： Takashi Ikeda ,  Seigo Sawada ,  Takashi Yaegashi ,  Takeshi Matsuzaki ,  Shusuke Hashimoto ,  Ryuta Yamazaki

    发明人： Takashi Ikeda ,  Seigo Sawada ,  Takashi Yaegashi ,  Takeshi Matsuzaki ,  Shusuke Hashimoto ,  Ryuta Yamazaki

    IPC分类号： C07D471/04 ,  A61K31/437 ,  A61P29/00 ,  A61P35/00 ,  C07D491/147

    CPC分类号： C07D471/04 ,  C07D491/147

    摘要： A novel compound having an excellent NFκB inhibitory effect is provided and specifically disclosed is a compound represented by the following formula (1) or a salt thereof:wherein, R1 represents a hydrogen atom, a lower alkyl group, a lower alkyloxy group, or a halogen atom;R2 represents a hydroxyl group, or a lower alkyloxy group;R3 represents a hydrogen atom, a lower alkyl group, or a halogen atom;R4 represents a hydrogen atom or a lower alkyloxy group;R5 represents a hydrogen atom, a lower alkyloxy group, a halogen atom, a hydroxyl group, or a methylenedioxy group formed together with R6 or an isopropylidenedioxy group formed together with R6;R6 represents a hydrogen atom, a lower alkyloxy group, or a methylenedioxy group formed together with R5 or an isopropylidenedioxy group formed together with R5;R7 represents a hydrogen atom or a lower alkyl group; andR8 represents a hydrogen atom, a hydroxyl group, an amino group, or a lower alkylcarbonyloxy group (excluding the case where R1, R3, R4 and R7 are hydrogen atoms, R2 and R8 are hydroxyl groups, and R5 and R6 are methoxy groups).

    摘要翻译： 提供了具有优异的NF＆Kgr B抑制效果的新化合物，具体公开了下式（1）表示的化合物或其盐：其中，R1表示氢原子，低级烷基，低级烷氧基， 或卤素原子; R2表示羟基或低级烷氧基; R3表示氢原子，低级烷基或卤素原子; R4表示氢原子或低级烷氧基; R5表示与R6一起形成的与R6或异丙烯二氧基一起形成的氢原子，低级烷氧基，卤素原子，羟基或亚甲二氧基; R6表示与R5一起形成的氢原子，低级烷氧基或亚甲二氧基，或与R5形成的异丙烯二氧基; R7表示氢原子或低级烷基; 并且R 8表示氢原子，羟基，氨基或低级烷基羰基氧基（R 1，R 3，R 4和R 7为氢原子的情况除外，R 2和R 8为羟基，R 5和R 6为甲氧基 ）。

    Banknote handling apparatus
    10.
    发明授权
    Banknote handling apparatus 有权
    钞票处理装置

    公开(公告)号：US08701858B2

    公开(公告)日：2014-04-22

    申请号：US13532294

    申请日：2012-06-25

    申请人： Michiharu Iwamura ,  Yoshikatsu Mizushima ,  Shusuke Hashimoto

    发明人： Michiharu Iwamura ,  Yoshikatsu Mizushima ,  Shusuke Hashimoto

    IPC分类号： G07F7/04

    CPC分类号： G07D11/0066 ,  G07D11/0063

    摘要： A banknote handling apparatus is operable in a code management mode in which banknotes stored in a storage unit are managed based on codes of the banknotes read by a recognition unit, and in a count management mode in which the banknotes stored in the storage unit are managed by counting the number of the banknotes to be stored in the storage unit. The banknote handling apparatus is switchable between the code management mode and the count management mode.

    摘要翻译： 纸币处理装置可以在代码管理模式下操作，其中存储在存储单元中的纸币基于由识别单元读取的纸币的代码进行管理，并且在存储在存储单元中的纸币被管理的计数管理模式 通过计数要存储在存储单元中的纸币的数量。 纸币处理装置可以在代码管理模式和计数管理模式之间切换。